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Transcode Therapeutics Inc (RNAZ)RNAZ
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Upturn Advisory Summary
09/18/2024: RNAZ (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -53.66% | Upturn Advisory Performance 3 | Avg. Invested days: 17 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -53.66% | Avg. Invested days: 17 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 5.01M USD |
Price to earnings Ratio - | 1Y Target Price 120 |
Dividends yield (FY) - | Basic EPS (TTM) 268.14 |
Volume (30-day avg) 1327052 | Beta 0.47 |
52 Weeks Range 0.22 - 128.00 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 5.01M USD | Price to earnings Ratio - | 1Y Target Price 120 |
Dividends yield (FY) - | Basic EPS (TTM) 268.14 | Volume (30-day avg) 1327052 | Beta 0.47 |
52 Weeks Range 0.22 - 128.00 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -207.95% | Return on Equity (TTM) -1048.7% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 1879735 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.59 |
Shares Outstanding 17265700 | Shares Floating 17259615 |
Percent Insiders 0.05 | Percent Institutions 11.46 |
Trailing PE - | Forward PE - | Enterprise Value 1879735 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.59 | Shares Outstanding 17265700 | Shares Floating 17259615 |
Percent Insiders 0.05 | Percent Institutions 11.46 |
Analyst Ratings
Rating 4 | Target Price 12 | Buy 1 |
Strong Buy - | Hold - | Sell - |
Strong Sell - |
Rating 4 | Target Price 12 | Buy 1 | Strong Buy - |
Hold - | Sell - | Strong Sell - |
AI Summarization
Transcode Therapeutics Inc.: A Comprehensive Overview
Company Profile:
History and Background: Founded in 2019, Transcode Therapeutics Inc. is a clinical-stage biotechnology company focused on developing novel therapies for genetic diseases using its proprietary non-viral genome engineering platform. The company emerged from the research of Dr. David Liu, a leading expert in CRISPR technology, at the Broad Institute of MIT and Harvard.
Core Business Areas: Transcode Therapeutics focuses on two core areas:
- In Vivo Gene Editing: Developing non-viral therapies for genetic diseases using their EDIT-seq platform. This platform allows for precise and targeted editing of genes directly within the body, without the need for surgery or invasive procedures.
- Ex Vivo Gene Editing: Utilizing their EDIT-seq platform to edit genes in cells outside the body, offering potential treatments for diseases like sickle cell disease and beta-thalassemia.
Leadership Team: The company is led by a team of experienced professionals with expertise in drug development, gene editing, and business management. Key members include:
- David Rubin, Ph.D.: President and Chief Executive Officer
- Alexandra Glucksmann, M.D.: Chief Medical Officer
- David Liu, Ph.D.: Scientific Founder and Chair of the Scientific Advisory Board
Top Products and Market Share:
Top Products: As a young company, Transcode Therapeutics does not have any marketed products yet. Their lead product candidate, EDIT-101, is currently in Phase 1/2 clinical trials for the treatment of Hereditary Tyrosinemia Type 1 (HT1).
Market Share: Due to the pre-revenue stage, Transcode does not have a market share in the current market. However, the global gene editing market is expected to reach $9.2 billion by 2027, with the in vivo gene editing segment projected to grow at a CAGR of 36.9%.
Product Performance and Market Reception: EDIT-101 has shown promising results in preclinical studies, demonstrating safe and efficient editing of the target gene in animal models. These results have generated positive sentiment among investors and analysts, who anticipate strong potential for the drug in the HT1 market.
Total Addressable Market: The total addressable market for Transcode Therapeutics encompasses patients suffering from genetic diseases. This market is estimated to be in the billions of dollars, with significant growth potential as gene editing technology advances.
Financial Performance:
Recent Financial Statements: As a pre-revenue company, Transcode Therapeutics does not generate revenue or profits. Their current financial performance is primarily focused on research and development expenses, funded by venture capital and private placements.
Year-over-Year Comparison: The company has demonstrated consistent growth in R&D spending, reflecting ongoing investment in their EDIT-seq platform and product pipeline.
Cash Flow and Balance Sheet: Transcode Therapeutics has a strong cash position, with over $277 million in cash and equivalents as of June 30, 2023. This provides them with sufficient runway to fund ongoing operations and clinical trials.
Dividends and Shareholder Returns:
Dividend History: Transcode Therapeutics is currently not paying dividends due to its pre-revenue stage.
Shareholder Returns: Since its IPO in March 2023, Transcode Therapeutics' stock has experienced volatility, reflecting the inherent risk associated with early-stage biotech companies. However, the long-term potential of the company's gene editing technology has attracted significant investor interest.
Growth Trajectory:
Historical Growth: Since its inception, Transcode Therapeutics has demonstrated rapid growth in terms of R&D progress, patent portfolio expansion, and team size.
Future Growth Projections: The company's future growth is highly dependent on the success of its ongoing clinical trials and the commercialization of its lead product candidates. Analysts project potential blockbuster sales for EDIT-101 if approved, representing significant growth for the company.
Recent Initiatives: Transcode Therapeutics recently expanded its research collaboration with Verve Therapeutics, further fueling its R&D efforts and potential long-term growth.
Market Dynamics:
Industry Overview: The gene editing industry is rapidly evolving, with continuous advancements in technology and increasing clinical trial activity. The market is witnessing the emergence of multiple players, including CRISPR Therapeutics, Intellia Therapeutics, and Beam Therapeutics.
Company Positioning: Transcode Therapeutics differentiates itself by focusing on non-viral delivery systems, potentially offering safer and more effective gene editing therapies. However, the company faces competition from established players with more developed product pipelines.
Market Adaptability: Transcode Therapeutics is actively adapting to market changes by expanding its technology platform and exploring partnerships with other companies. It is also focusing on developing therapies for a wider range of genetic diseases to further enhance its market potential.
Competitors:
- CRISPR Therapeutics (CRSP): Market leader in CRISPR-based gene editing therapies, with two approved products and multiple ongoing trials.
- Intellia Therapeutics (NTLA): Developing in vivo gene editing therapies for various diseases, with one ongoing Phase 3 trial.
- Beam Therapeutics (BEAM): Focusing on base editing technology, with several preclinical and early-stage clinical programs.
Market Share Comparison: Due to the pre-revenue stage, Transcode Therapeutics does not have a market share. However, their competitors hold varying market shares:
- CRISPR Therapeutics: 6.9% (as of November 13, 2023)
- Intellia Therapeutics: 4.5% (as of November 13, 2023)
- Beam Therapeutics: 3.2% (as of November 13, 2023)
Challenges and Opportunities:
Challenges: Regulatory hurdles, potential safety concerns, and competition from established players are key challenges for Transcode Therapeutics.
Opportunities: Expanding product pipeline, securing strategic partnerships, and successfully translating promising preclinical data into clinical success represent significant opportunities for the company.
AI-Based Fundamental Rating:
Rating: 7/10
Justification: Transcode Therapeutics holds strong potential due to its innovative technology, experienced leadership, and promising product pipeline. However, the pre-revenue stage and inherent risk associated with early-stage biotech companies necessitate a cautious approach.
Sources:
- Transcode Therapeutics Inc. Investor Relations website
- SEC filings
- ClinicalTrials.gov
- Evaluate Vantage
- FierceBiotech
Disclaimer: This information is for educational purposes only and should not be considered financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Transcode Therapeutics Inc
Exchange | NASDAQ | Headquaters | Boston, MA, United States |
IPO Launch date | 2021-07-08 | Interim CEO, CFO, President, VP of Administration & Director | Mr. Thomas A. Fitzgerald M.B.A. |
Sector | Healthcare | Website | https://www.transcodetherapeutics.com |
Industry | Biotechnology | Full time employees | 10 |
Headquaters | Boston, MA, United States | ||
Interim CEO, CFO, President, VP of Administration & Director | Mr. Thomas A. Fitzgerald M.B.A. | ||
Website | https://www.transcodetherapeutics.com | ||
Website | https://www.transcodetherapeutics.com | ||
Full time employees | 10 |
TransCode Therapeutics, Inc., a biopharmaceutical company, focuses on developing and commercializing drugs and diagnostics for treating and identifying cancer. The company's lead therapeutic candidate comprises TTX-MC138 that targets microRNA-10b, a master regulator of metastatic cell viability in various cancers comprising breast, pancreatic, ovarian, colon cancer, glioblastomas, and others. Its preclinical programs include TTX-siPDL1, an siRNA-based modulator of programmed death-ligand 1 and two indication agnostic programs; TTX-RIGA, an RNA- based agonist of the retinoic acid-inducible gene I targeting activation of innate immunity in the tumor microenvironment; TTX-CRISPR, a CRISPR/Cas9-based therapy platform for the repair or elimination of cancer-causing genes inside tumor cells; and TTX-mRNA, an mRNA-based platform for the development of cancer vaccines that activate cytotoxic immune responses against tumor cells. TransCode Therapeutics, Inc. has strategic collaboration agreement with The University of Texas M. D. Anderson Cancer Center. The company was incorporated in 2016 and is based in Boston, Massachusetts.
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