Upturn unsubscribed user
$1.14/ day, billed weekly
Cancel anytime
(Ad-Free, Unlimited access)​
NO CREDIT CARD REQUIRED
OKUR
Upturn stock ratingUpturn stock rating

OnKure Therapeutics, Inc. (OKUR)

Upturn stock ratingUpturn stock rating
$4.26
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

04/01/2025: OKUR (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

ratingratingratingratingrating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

ratingratingratingratingrating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit 119.59%
Avg. Invested days 34
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 5.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 76.57M USD
Price to earnings Ratio 71.75
1Y Target Price 34.2
Price to earnings Ratio 71.75
1Y Target Price 34.2
Volume (30-day avg) 30663
Beta -
52 Weeks Range 4.11 - 20.00
Updated Date 04/1/2025
52 Weeks Range 4.11 - 20.00
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) 0.08

Earnings Date

Report Date 2025-03-11
When -
Estimate -
Actual -2.755

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -
Return on Equity (TTM) -

Valuation

Trailing PE 71.75
Forward PE -
Enterprise Value 565252
Price to Sales(TTM) -
Enterprise Value 565252
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA 0.57
Shares Outstanding 12652900
Shares Floating 4190656
Shares Outstanding 12652900
Shares Floating 4190656
Percent Insiders 1.45
Percent Institutions 96.85

Analyst Ratings

Rating 4.75
Target Price -
Buy 1
Strong Buy 3
Buy 1
Strong Buy 3
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

OnKure Therapeutics, Inc.

stock logo

Company Overview

History and Background

OnKure Therapeutics, Inc. is a biopharmaceutical company focused on developing and commercializing innovative medicines to treat cancer. While specific founding details are not widely available, they are a clinical-stage company with programs targeting key cancer pathways.

Core Business Areas

  • Drug Development: Focuses on the discovery and development of small molecule therapeutics for cancer treatment. This includes pre-clinical research, clinical trials, and regulatory submissions.
  • Clinical Trials: Conducts clinical trials to evaluate the safety and efficacy of their drug candidates in various cancer types.
  • Commercialization: Aims to commercialize their approved therapies through partnerships or direct sales.

Leadership and Structure

Information on the specific leadership team and organizational structure of OnKure Therapeutics, Inc. is generally available on their corporate website and investor relations pages.

Top Products and Market Share

Key Offerings

  • OKI-179: A selective PI3Ku03b1 inhibitor in Phase 1b clinical trials for advanced solid tumors. Market share data not publicly available. Competitors include other PI3K inhibitors from companies like Novartis (NVS), Bayer (BAYRY), and Roche (RHHBY).
  • OKI-219: A novel small molecule in preclinical development, targeting a novel cancer target. Market share data not publicly available as it is in preclinical. Competitors are dependent on the specific target addressed.

Market Dynamics

Industry Overview

The biopharmaceutical industry is characterized by high R&D costs, lengthy regulatory approval processes, and intense competition. The oncology market is a major segment, driven by the increasing prevalence of cancer and advancements in targeted therapies and immunotherapies.

Positioning

OnKure Therapeutics, Inc. is positioned as an innovative drug developer focused on targeted therapies for cancer. Their competitive advantage lies in their novel drug candidates and expertise in specific cancer pathways.

Total Addressable Market (TAM)

The global oncology market is projected to reach hundreds of billions of dollars. OnKure Therapeutics, Inc. is targeting specific niches within this market with their novel therapies, aiming to capture a portion of the TAM.

Upturn SWOT Analysis

Strengths

  • Novel drug candidates
  • Targeted therapy approach
  • Experienced management team
  • Strong scientific expertise

Weaknesses

  • Limited financial resources
  • Dependence on clinical trial success
  • Small company size
  • No currently marketed products

Opportunities

  • Partnerships with larger pharmaceutical companies
  • Successful clinical trial outcomes
  • Expansion into new cancer indications
  • Acquisition by a larger company

Threats

  • Clinical trial failures
  • Competition from larger pharmaceutical companies
  • Regulatory hurdles
  • Patent expirations

Competitors and Market Share

Key Competitors

  • NVS
  • BAYRY
  • RHHBY

Competitive Landscape

OnKure faces competition from established pharmaceutical companies with greater resources. Their advantage lies in their unique drug candidates and targeted approach.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Growth is primarily driven by progress in clinical trials and securing funding. No specific revenue growth data available.

Future Projections: Future growth depends on the successful development and commercialization of their drug candidates. Analyst estimates are not readily available due to the company's private status or limited public information.

Recent Initiatives: Recent initiatives likely include advancing their clinical trials for OKI-179 and progressing preclinical development of OKI-219.

Summary

OnKure Therapeutics is a clinical-stage biopharmaceutical company focusing on targeted cancer therapies. Its strengths lie in its novel drug candidates and focused approach, while weaknesses include limited financial resources and reliance on clinical trial success. Opportunities include partnerships and expansion into new indications, but threats include competition and regulatory hurdles. The future of OnKure hinges on successfully navigating the complex drug development and commercialization process.

Similar Companies

  • NVS
  • BAYRY
  • RHHBY

Sources and Disclaimers

Data Sources:

  • Company Website
  • Publicly Available Clinical Trial Data
  • Industry Reports
  • Analyst Reports (if available)

Disclaimers:

This analysis is based on publicly available information and may not be entirely comprehensive. The biopharmaceutical industry is inherently risky, and past performance is not indicative of future results. Market share estimations are rough and for illustrative purposes only.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About OnKure Therapeutics, Inc.

Exchange NASDAQ
Headquaters Boulder, CO, United States
IPO Launch date 2024-10-07
President, CEO & Director Dr. Nicholas A. Saccomano Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 46
Full time employees 46

OnKure Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision medicines that target biologically validated drivers of cancers. Its lead product candidate includes OKI-219, a selective inhibitor of phosphoinositide 3 kinase alpha harboring the H1047R mutation that is in Phase 1 clinical trial for the treatment of solid tumors, including breast cancer. The company is headquartered in Boulder, Colorado.

Upturn is now on iOS and Android!

Experience Upturn on your mobile. Install it now!​