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VTYX
Upturn stock ratingUpturn stock rating

Ventyx Biosciences Inc (VTYX)

Upturn stock ratingUpturn stock rating
$1.07
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

04/01/2025: VTYX (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type Stock
Historic Profit -51.19%
Avg. Invested days 27
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 85.69M USD
Price to earnings Ratio -
1Y Target Price 12
Price to earnings Ratio -
1Y Target Price 12
Volume (30-day avg) 777188
Beta 0.58
52 Weeks Range 1.07 - 5.66
Updated Date 04/1/2025
52 Weeks Range 1.07 - 5.66
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.88

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -33.48%
Return on Equity (TTM) -54.27%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -124372788
Price to Sales(TTM) -
Enterprise Value -124372788
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -22.93
Shares Outstanding 71130096
Shares Floating 49589028
Shares Outstanding 71130096
Shares Floating 49589028
Percent Insiders 4.46
Percent Institutions 84.53

Analyst Ratings

Rating 4.22
Target Price 11.14
Buy 1
Strong Buy 5
Buy 1
Strong Buy 5
Hold 3
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Ventyx Biosciences Inc

stock logo

Company Overview

overview logo History and Background

Ventyx Biosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative medicines for autoimmune and inflammatory diseases. Founded in 2020, the company rapidly advanced its pipeline through strategic acquisitions and internal development programs.

business area logo Core Business Areas

  • TYK2 Inhibitor Program: Development of oral, selective allosteric TYK2 inhibitors for the treatment of autoimmune and inflammatory diseases like psoriasis, psoriatic arthritis, Crohn's disease, and ulcerative colitis.
  • S1P1R Modulator Program: Development of S1P1R modulators for the treatment of autoimmune diseases, potentially offering differentiated safety and efficacy profiles.
  • NLRP3 Inhibitor Program: Development of NLRP3 inhibitors to target inflammatory conditions driven by the NLRP3 inflammasome.

leadership logo Leadership and Structure

Ventyx is led by a management team with experience in drug development and commercialization. The company has a board of directors providing strategic oversight.

Top Products and Market Share

overview logo Key Offerings

  • VAY736 (TYK2 inhibitor): VAY736 is an oral, selective allosteric TYK2 inhibitor currently in clinical development for psoriasis, psoriatic arthritis, and Crohn's disease. Competing TYK2 inhibitors include BMS's Sotyktu (deucravacitinib) and Takeda's TAK-279.
  • VTX3232 (S1P1R modulator): VTX3232 is an oral S1P1R modulator being developed for autoimmune diseases. Competitors include Novartis' Gilenya (fingolimod), Bristol Myers Squibb's Zeposia (ozanimod), and Johnson & Johnson's Ponvory (ponesimod).
  • VTX2735 (NLRP3 inhibitor): VTX2735 is a peripherally restricted NLRP3 inhibitor targeting inflammatory conditions. Competitors in NLRP3 inhibition are numerous, including large pharma pursuing systemic NLRP3 inhibitors.

Market Dynamics

industry overview logo Industry Overview

The autoimmune and inflammatory disease market is a large and growing market with unmet medical needs. The industry is characterized by high research and development costs and complex regulatory pathways.

Positioning

Ventyx aims to differentiate itself by developing oral, selective inhibitors and modulators with improved safety and efficacy profiles. Their approach targets specific pathways involved in autoimmune and inflammatory diseases.

Total Addressable Market (TAM)

The TAM for autoimmune and inflammatory disease therapies is estimated to be over $100 billion annually. Ventyx aims to capture a significant portion of this market by addressing unmet needs with its novel therapies.

Upturn SWOT Analysis

Strengths

  • Strong pipeline of clinical-stage assets
  • Experienced management team
  • Targeting large and growing market
  • Differentiated approach with oral, selective inhibitors

Weaknesses

  • Clinical trial risks and potential setbacks
  • Reliance on successful development and commercialization
  • Competition from established pharmaceutical companies
  • High cash burn rate

Opportunities

  • Positive clinical trial results
  • Partnerships with larger pharmaceutical companies
  • Expansion into new indications
  • Regulatory approvals

Threats

  • Failure to demonstrate efficacy in clinical trials
  • Adverse safety events
  • Regulatory delays or rejection
  • Competition from new therapies

Competitors and Market Share

competitor logo Key Competitors

  • BMY
  • NVS
  • JNJ
  • TAK

Competitive Landscape

Ventyx faces competition from established pharmaceutical companies with greater resources and established market presence. Ventyx aims to differentiate itself through innovative therapies and strategic partnerships.

Major Acquisitions

Oppilan Pharma

  • Year: 2022
  • Acquisition Price (USD millions): 105
  • Strategic Rationale: Expanded Ventyx's pipeline with an oral peripherally restricted NLRP3 inhibitor program for inflammatory diseases.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is limited due to the company's relatively recent founding.

Future Projections: Future growth is dependent on the successful development and commercialization of its pipeline assets. Analyst estimates vary based on clinical trial outcomes and regulatory approvals.

Recent Initiatives: Recent initiatives include advancing clinical trials for VAY736, VTX3232 and VTX2735 and expanding the pipeline through strategic acquisitions.

Summary

Ventyx Biosciences is a clinical-stage biopharmaceutical company with a promising pipeline focused on autoimmune and inflammatory diseases. The company's success hinges on positive clinical trial outcomes and successful commercialization. They face significant competition from established pharmaceutical companies, but their differentiated approach offers potential advantages. Ventyx needs to continue to execute its clinical programs and secure partnerships to enhance its market position.

Similar Companies

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JNJratingrating

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NVSratingrating

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TAKratingrating

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Sources and Disclaimers

Data Sources:

  • Company filings
  • Analyst reports
  • Company press releases
  • ClinicalTrials.gov

Disclaimers:

This analysis is for informational purposes only and does not constitute investment advice. Investment decisions should be based on individual risk tolerance and due diligence.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Ventyx Biosciences Inc

Exchange NASDAQ
Headquaters San Diego, CA, United States
IPO Launch date 2021-10-21
Founder, CEO, President & Director Dr. Raju S. Mohan Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 79
Full time employees 79

Ventyx Biosciences, Inc., a clinical-stage biopharmaceutical company, develops oral therapies for patients with autoimmune, inflammatory, and neurodegenerative diseases. The company's lead clinical product candidate is VTX958, a selective allosteric tyrosine kinase type 2 inhibitor for Crohn's disease. It is also developing Tamuzimod, a sphingosine 1 phosphate receptor modulator that is in Phase II clinical trials for the treatment of ulcerative colitis; and VTX2735, a peripheral NOD-like receptor protein 3 inflammasome inhibitor to treat patients with cryopyrin-associated periodic syndrome. In addition, the company develops VTX3232, a CNS-penetrant NLRP3 inhibitor that is in Phase 2a trial for patients with early Parkinson's disease and is in Phase 2 trial for patients with obesity and additional risk factors for cardiovascular disease. Ventyx Biosciences, Inc. was incorporated in 2018 and is headquartered in San Diego, California.

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