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Shattuck Labs Inc (STTK)



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Upturn Advisory Summary
04/01/2025: STTK (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit 83.25% | Avg. Invested days 26 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 40.52M USD | Price to earnings Ratio - | 1Y Target Price 2.6 |
Price to earnings Ratio - | 1Y Target Price 2.6 | ||
Volume (30-day avg) 185120 | Beta 1.67 | 52 Weeks Range 0.85 - 11.76 | Updated Date 04/1/2025 |
52 Weeks Range 0.85 - 11.76 | Updated Date 04/1/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.49 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -1404.39% |
Management Effectiveness
Return on Assets (TTM) -40.07% | Return on Equity (TTM) -67.23% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -24223504 | Price to Sales(TTM) 7.08 |
Enterprise Value -24223504 | Price to Sales(TTM) 7.08 | ||
Enterprise Value to Revenue 18.32 | Enterprise Value to EBITDA -3.62 | Shares Outstanding 47739700 | Shares Floating 24176183 |
Shares Outstanding 47739700 | Shares Floating 24176183 | ||
Percent Insiders 14.26 | Percent Institutions 65.16 |
Analyst Ratings
Rating 3.8 | Target Price 1.2 | Buy - | Strong Buy 2 |
Buy - | Strong Buy 2 | ||
Hold 3 | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Shattuck Labs Inc

Company Overview
History and Background
Shattuck Labs, Inc. is a clinical-stage biotechnology company pioneering the development of novel cancer therapeutics. It was founded with the goal of creating a new class of oncology drugs by modulating the immune system. Details on founding year and early milestones are not publicly available.
Core Business Areas
- Agonist Redirected Checkpoint (ARC) platform: Shattuck's ARC platform engineers novel fusion proteins that combine checkpoint inhibition with T cell costimulation to enhance the antitumor immune response.
- Gamma Delta T Cell Engager (GADLEN) Platform: The GADLEN platform is used to create novel fusion proteins that target and activate gamma delta T cells to kill cancer cells.
Leadership and Structure
The leadership team includes key executives focused on research, development, and commercialization. The organizational structure likely involves dedicated teams for each platform (ARC and GADLEN) and other functional areas.
Top Products and Market Share
Key Offerings
- SL-172154 (SIRPu03b1-Fc-CD40L): SL-172154 is an ARC fusion protein targeting the SIRPu03b1 checkpoint and the CD40 costimulatory molecule. It is currently in clinical development. Market share data and revenue are not yet available as it is pre-revenue. Competitors include companies developing other CD40 agonists and SIRPu03b1 inhibitors (e.g., ALBO, JTX).
- SL-279252 (MAGEA4-CD3 bispecific): SL-279252 is a GADLEN bispecific antibody targeting the MAGEA4 tumor antigen and the CD3 receptor on gamma delta T cells. It is in preclinical development. Market share data and revenue are not yet available. Competitors include companies developing bispecific antibodies (e.g., XOMA) and gamma delta T-cell therapies.
Market Dynamics
Industry Overview
The biotechnology industry, particularly the oncology therapeutics sector, is highly competitive and innovative. Companies are focused on developing new therapies to improve cancer treatment outcomes.
Positioning
Shattuck Labs aims to differentiate itself through its ARC and GADLEN platforms, which offer unique approaches to modulating the immune system for cancer therapy. Its competitive advantage lies in the novelty of these platforms.
Total Addressable Market (TAM)
The total addressable market for cancer immunotherapies is estimated to be in the tens of billions of dollars. Shattuck Labs is positioned to capture a portion of this market by developing novel therapies that address unmet needs in cancer treatment.
Upturn SWOT Analysis
Strengths
- Novel ARC and GADLEN platforms
- Experienced management team
- Promising preclinical and clinical data
- Strong intellectual property position
Weaknesses
- Limited financial resources compared to larger pharmaceutical companies
- Early-stage clinical development risks
- Dependence on the success of its lead programs
- High attrition rate in drug development
Opportunities
- Potential for strategic partnerships with larger pharmaceutical companies
- Expansion of the ARC and GADLEN platforms to new cancer targets
- Advancement of clinical programs to late-stage development
- Potential for breakthrough therapy designations
Threats
- Competition from other immunotherapy companies
- Regulatory hurdles and approval delays
- Clinical trial failures
- Patent challenges
Competitors and Market Share
Key Competitors
- ALBO
- JTX
- XOMA
Competitive Landscape
Shattuck Labs is competing in the highly competitive immuno-oncology space. It faces competition from established pharmaceutical companies and other biotechnology companies developing novel cancer therapies. Its advantages lie in its novel ARC and GADLEN platforms, but it needs to successfully translate its science into clinical success.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth data is not included due to lack of specifics.
Future Projections: Future growth is dependent on the successful development and commercialization of its ARC and GADLEN-based therapies.
Recent Initiatives: Recent initiatives include progressing lead clinical candidates through Phase 1/2 trials, expanding preclinical programs, and forging strategic partnerships.
Summary
Shattuck Labs is an early-stage biotechnology company pioneering novel immuno-oncology therapies, specifically utilizing its ARC and GADLEN platforms. It's working well with its novel platforms and preclinical development but it needs to progress to clinical trials. The company faces competition and relies on successful program development, which carries risk.
Similar Companies
XOMA

XOMA Corp


XOMA

XOMA Corp
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
- Press Releases
Disclaimers:
The data provided is for informational purposes only and should not be considered investment advice. Market share data is estimated and may not be precise. Financial data is based on publicly available information and may be subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Shattuck Labs Inc
Exchange NASDAQ | Headquaters Austin, TX, United States | ||
IPO Launch date 2020-10-09 | Co-Founder, CEO & Director Dr. Taylor H. Schreiber M.D., Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 44 | Website https://www.shattucklabs.com |
Full time employees 44 | Website https://www.shattucklabs.com |
Shattuck Labs, Inc., a clinical-stage biotechnology company, develops therapeutics for the treatment of cancer and autoimmune disease in the United States. The company's lead product candidate is SL-172154, which is in Phase 1 clinical trial for the treatment of ovarian, fallopian tube, and peritoneal cancers. Shattuck Labs, Inc. was incorporated in 2016 and is headquartered in Austin, Texas.
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