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Personalis Inc (PSNL)

Upturn stock ratingUpturn stock rating
$3.45
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

04/01/2025: PSNL (3-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

AI Based Fundamental Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -41.27%
Avg. Invested days 26
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 304.51M USD
Price to earnings Ratio -
1Y Target Price 7.33
Price to earnings Ratio -
1Y Target Price 7.33
Volume (30-day avg) 1047126
Beta 1.73
52 Weeks Range 1.14 - 7.20
Updated Date 04/1/2025
52 Weeks Range 1.14 - 7.20
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.37

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -96.06%
Operating Margin (TTM) -107.81%

Management Effectiveness

Return on Assets (TTM) -17.23%
Return on Equity (TTM) -48.91%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 168159441
Price to Sales(TTM) 3.6
Enterprise Value 168159441
Price to Sales(TTM) 3.6
Enterprise Value to Revenue 1.99
Enterprise Value to EBITDA -0.03
Shares Outstanding 88263296
Shares Floating 52082390
Shares Outstanding 88263296
Shares Floating 52082390
Percent Insiders 31.34
Percent Institutions 42.75

Analyst Ratings

Rating 4.33
Target Price 7.98
Buy 2
Strong Buy 3
Buy 2
Strong Buy 3
Hold 1
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Personalis Inc

stock logo

Company Overview

overview logo History and Background

Personalis, Inc. was founded in 2011 and is based in Menlo Park, California. It focuses on advanced genomics for cancer and other complex diseases. Initially focused on whole genome sequencing, it has evolved to provide comprehensive genomic analysis solutions for cancer immunotherapy and precision medicine.

business area logo Core Business Areas

  • NeXT Platform: Offers comprehensive genomic and proteomic analysis, including whole genome and exome sequencing, RNA sequencing, and proteomic profiling. Primarily used in immuno-oncology and clinical trials.
  • Pharma Services: Provides customized genomic solutions for pharmaceutical companies, supporting drug development and clinical trials. This includes biomarker discovery, patient stratification, and monitoring treatment response.

leadership logo Leadership and Structure

John West is the CEO. The company operates with a functional organizational structure, with departments for research and development, commercial operations, and finance.

Top Products and Market Share

overview logo Key Offerings

  • NeXT Personal: A comprehensive cancer genomic profiling test designed to identify personalized treatment options. Data on market share or revenue specifically attributed to this product is not publicly available. Competitors include Foundation Medicine (FMI), Guardant Health (GH), and Exact Sciences (EXAS).
  • ImmunoID NeXT Platform: A platform to comprehensively profile both the tumor and the immune microenvironment. Data on market share or revenue specifically attributed to this product is not publicly available. Competitors include NanoString Technologies (NSTG) and Adaptive Biotechnologies (ADPT).

Market Dynamics

industry overview logo Industry Overview

The market for cancer genomics and precision medicine is growing, driven by advancements in sequencing technologies and the increasing adoption of personalized treatment approaches. Key drivers include demand for more targeted therapies, expanding use of liquid biopsies, and increased investment in genomics research.

Positioning

Personalis is positioned as a provider of comprehensive genomic and proteomic profiling solutions, focusing on advanced sequencing technologies and immuno-oncology. Its competitive advantage lies in the breadth and depth of its platform, enabling detailed analysis of both tumor and immune system interactions.

Total Addressable Market (TAM)

The TAM for precision oncology is estimated to be in the tens of billions of dollars annually and is growing. Personalis is positioned to capture a share of this market through its advanced genomic solutions for biopharma companies.

Upturn SWOT Analysis

Strengths

  • Comprehensive genomic and proteomic platform
  • Expertise in immuno-oncology
  • Strong relationships with pharmaceutical companies
  • Advanced sequencing technologies

Weaknesses

  • Reliance on a limited number of key customers
  • High operating expenses
  • Negative profitability
  • Stock Dilution

Opportunities

  • Expanding applications of genomics in drug development
  • Increasing demand for personalized cancer therapies
  • Partnerships with leading research institutions
  • Growth in liquid biopsy market

Threats

  • Competition from larger, more established genomics companies
  • Pricing pressure from commoditization of sequencing services
  • Regulatory hurdles for new genomic tests
  • Economic downturn affecting research budgets

Competitors and Market Share

competitor logo Key Competitors

  • FMI
  • GH
  • EXAS
  • NSTG
  • ADPT

Competitive Landscape

Personalis competes with larger, more established genomics companies. Its competitive advantage lies in its comprehensive genomic and proteomic platform, but it faces challenges in terms of market share and financial resources.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Personalis's historical growth has been driven by its collaborations with pharmaceutical companies and its increasing adoption in clinical trials.

Future Projections: Future growth projections would depend on analyst estimates. However, growth is expected to be driven by demand for personalized cancer therapies and expanding applications of genomics in drug development.

Recent Initiatives: Recent strategic initiatives would require gathering the latest information from press releases, investor presentations, and corporate filings.

Summary

Personalis is a specialized genomics company focused on cancer, with strengths in its platform and pharma partnerships. However, it faces stiff competition and has yet to achieve profitability. Future growth depends on capitalizing on opportunities in personalized medicine and expanding its customer base. The company needs to closely monitor cash flow, maintain key customer relationships, and leverage its technological advantages.

Similar Companies

  • FMI
  • GH
  • EXAS
  • NSTG
  • ADPT

Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Analyst Reports
  • Press Releases

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Market share estimates are approximate and based on available data. Financial data may be outdated and should be verified with official sources.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Personalis Inc

Exchange NASDAQ
Headquaters Fremont, CA, United States
IPO Launch date 2019-06-20
President, CEO & Director Mr. Christopher M. Hall
Sector Healthcare
Industry Diagnostics & Research
Full time employees 228
Full time employees 228

Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD), therapy response and recurrence monitoring in solid tumor cancers; and ImmunoID NeXT, a tissue-based service that combines whole exome and whole transcriptome sequencing data with advanced analytics to provide a multi-dimensional view of the tumor and the tumor microenvironment from a single sample. It also provides NeXT Personal Dx, a tumor-informed liquid biopsy test for the detection of MRD; and NeXT Dx, a tumor profiling test that is used to help select therapy for a cancer patient and identify potential clinical trials for a patient. In addition, the company performs whole exome sequencing of cancer tissue and matched blood samples for diagnostic companies as an input to their products; and whole genome sequencing on human samples for research projects, such as population sequencing initiatives. Its services are used by pharmaceutical companies for translational research, biomarker discovery, the development of personalized cancer therapies, and for clinical trials, as well as tests are used by physicians to detect residual or recurrent cancer in patients, monitor cancer response to therapy, and uncover insights for therapy selection. The company's customers include pharmaceutical companies, biopharmaceutical companies, diagnostics companies, universities, non-profits, government entities, and patients. Personalis, Inc. was incorporated in 2011 and is headquartered in Fremont, California.

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