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PMN
Upturn stock ratingUpturn stock rating

ProMIS Neurosciences Inc. (PMN)

Upturn stock ratingUpturn stock rating
$0.73
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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  • WEEK

Upturn Advisory Summary

03/06/2025: PMN (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type Stock
Historic Profit -53.5%
Avg. Invested days 28
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 03/06/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 22.88M USD
Price to earnings Ratio 17.39
1Y Target Price 7.69
Price to earnings Ratio 17.39
1Y Target Price 7.69
Volume (30-day avg) 50056
Beta 0.58
52 Weeks Range 0.62 - 2.61
Updated Date 04/1/2025
52 Weeks Range 0.62 - 2.61
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) 0.04

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -43.35%
Return on Equity (TTM) -8.03%

Valuation

Trailing PE 17.39
Forward PE -
Enterprise Value 1166075
Price to Sales(TTM) 5168.19
Enterprise Value 1166075
Price to Sales(TTM) 5168.19
Enterprise Value to Revenue 3868.08
Enterprise Value to EBITDA -1.74
Shares Outstanding 32689200
Shares Floating 17461912
Shares Outstanding 32689200
Shares Floating 17461912
Percent Insiders 27.56
Percent Institutions 29.84

Analyst Ratings

Rating 4.67
Target Price 7.7
Buy 1
Strong Buy 2
Buy 1
Strong Buy 2
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

ProMIS Neurosciences Inc.

stock logo

Company Overview

overview logo History and Background

ProMIS Neurosciences Inc. is a biotechnology company focused on discovering and developing antibody therapeutics selectively targeting toxic oligomers implicated in the development of neurodegenerative diseases, in particular Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD). Founded to address the need for more effective therapies for these diseases.

business area logo Core Business Areas

  • Drug Discovery: Discovery of antibody therapeutics against misfolded proteins in neurodegenerative diseases.
  • Preclinical Development: Advancing antibody candidates through preclinical testing.
  • Partnerships and Licensing: Establishing partnerships to advance clinical development and commercialization.

leadership logo Leadership and Structure

ProMIS Neurosciences Inc. is led by a team of scientists and business professionals with expertise in neurodegenerative disease research and drug development. The organizational structure includes research, development, and corporate functions.

Top Products and Market Share

overview logo Key Offerings

  • PMN310: A monoclonal antibody targeting toxic amyloid-beta oligomers in Alzheimer's disease. Currently in preclinical development. Competitors include Biogen, Eisai, Eli Lilly.
  • ALS Programs: Developing antibody therapeutics for ALS. Competitors include Amylyx Pharmaceuticals and Biogen.

Market Dynamics

industry overview logo Industry Overview

The neurodegenerative disease market is large and growing, driven by an aging population and increasing prevalence of diseases such as Alzheimer's and Parkinson's. There is a significant unmet need for effective therapies.

Positioning

ProMIS Neurosciences Inc. focuses on targeting toxic protein aggregates, a differentiated approach in the neurodegenerative disease field. Competitive advantages include its discovery platform and selective antibody candidates.

Total Addressable Market (TAM)

The global Alzheimer's disease market is estimated to reach billions of dollars. ProMIS Neurosciences Inc. aims to capture a portion of this market with its targeted antibody therapeutics.

Upturn SWOT Analysis

Strengths

  • Proprietary discovery platform
  • Selective antibody candidates
  • Experienced leadership team
  • Focus on disease-modifying therapies

Weaknesses

  • Early stage of development
  • High dependence on financing
  • Limited clinical data
  • Small company size

Opportunities

  • Partnerships with larger pharmaceutical companies
  • Advancement of clinical programs
  • Expansion into new indications
  • Increasing prevalence of neurodegenerative diseases

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from established pharmaceutical companies
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • BIIB
  • LLY
  • ESAI

Competitive Landscape

ProMIS Neurosciences Inc. faces competition from larger pharmaceutical companies with more resources. However, its focus on targeting toxic protein aggregates provides a differentiated approach.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by expansion of research programs and preclinical development activities.

Future Projections: Future growth is contingent on successful clinical development of antibody candidates and partnerships. Analyst estimates vary depending on program progress.

Recent Initiatives: Focus on advancing PMN310 into clinical trials and expanding collaborations.

Summary

ProMIS Neurosciences Inc. is an early-stage biotechnology company with a promising approach to treating neurodegenerative diseases. Its strengths lie in its proprietary technology and selective antibody candidates. However, it faces challenges related to financing, clinical development, and competition. Success hinges on advancing its programs and securing partnerships.

Similar Companies

  • BIIB
  • LLY
  • ESAI

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports
  • Industry publications

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. The information provided is based on publicly available data and may not be complete or accurate.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About ProMIS Neurosciences Inc.

Exchange NASDAQ
Headquaters Toronto, ON, Canada
IPO Launch date 2007-07-17
CEO, President & Director Mr. Neil K. Warma M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 6
Full time employees 6

ProMIS Neurosciences, Inc. discovers and develops antibody therapies and therapeutic vaccines neurodegenerative diseases and other misfolded protein diseases in Canada. The company's proprietary discovery platform comprises ProMIS and Collective Coordinates algorithms to predict novel targets known as disease specific epitopes on the molecular surface of misfolded proteins. Its lead product candidates comprise of PMN310, a monoclonal antibody (mAb) for toxic oligomers in AD; PMN267, a TDP-43; and PMN442, a mAb targeting toxic a-syn oligomers and seeding fibrils. The company was formerly known as Amorfix Life Sciences Ltd. and changed its name to ProMIS Neurosciences, Inc. in July 2015. ProMIS Neurosciences, Inc. was incorporated in 2004 and is headquartered in Toronto, Canada.

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