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Neurosense Therapeutics Ltd (NRSN)NRSN
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Upturn Advisory Summary
09/18/2024: NRSN (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -55.87% | Upturn Advisory Performance 3 | Avg. Invested days: 36 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -55.87% | Avg. Invested days: 36 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 26.09M USD |
Price to earnings Ratio - | 1Y Target Price 5.25 |
Dividends yield (FY) - | Basic EPS (TTM) -0.93 |
Volume (30-day avg) 312167 | Beta 1.5 |
52 Weeks Range 0.40 - 2.33 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 26.09M USD | Price to earnings Ratio - | 1Y Target Price 5.25 |
Dividends yield (FY) - | Basic EPS (TTM) -0.93 | Volume (30-day avg) 312167 | Beta 1.5 |
52 Weeks Range 0.40 - 2.33 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -222.17% | Return on Equity (TTM) -494.84% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 25411148 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -1.16 |
Shares Outstanding 19471000 | Shares Floating 10352241 |
Percent Insiders 25.43 | Percent Institutions 8.58 |
Trailing PE - | Forward PE - | Enterprise Value 25411148 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -1.16 | Shares Outstanding 19471000 | Shares Floating 10352241 |
Percent Insiders 25.43 | Percent Institutions 8.58 |
Analyst Ratings
Rating 4.5 | Target Price 7.25 | Buy 1 |
Strong Buy 1 | Hold - | Sell - |
Strong Sell - |
Rating 4.5 | Target Price 7.25 | Buy 1 | Strong Buy 1 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Neurosense Therapeutics Ltd.: A Comprehensive Overview
Company Profile:
Detailed history and background:
Neurosense Therapeutics Ltd. (NSENSE), established in 2010, is a clinical-stage biopharmaceutical company based in Tel Aviv, Israel. Its primary focus lies in developing innovative therapies for the treatment of neurological and other debilitating diseases. NSENSE boasts a robust portfolio encompassing several proprietary, first-in-class product candidates with distinct mechanisms of action. The company's lead program, NTRX-101, targets the treatment of neuropathic pain, while its other development pipeline includes NTRX-201 for spinal cord injury and NTRX-301 for ALS, among others.
Core business areas:
NSENSE dedicates its efforts to the discovery, development, and commercialization of novel therapeutics that address significant unmet medical needs. The company prioritizes its research on neurological disorders, with a specific focus on chronic pain conditions, spinal cord injuries, and neurodegenerative diseases.
Leadership team and corporate structure:
Neurosense Therapeutics boasts a seasoned team of experts, led by Dror E. Robinson, Ph.D., serving as CEO and President. The leadership further encompasses experienced figures like Dr. Michael O'Neill as Chairman, Dr. Orli Ben-Moshe as Chief Operating Officer, and Dr. Amir Hadar as Chief Medical Officer.
Top Products and Market Share:
Products and offerings:
- NTRX-101: This lead candidate for the treatment of neuropathic pain exhibits a unique dual-mode of action, targeting both peripheral nerve pathways and central sensitization mechanisms.
- NTRX-201: Designed for the treatment of spinal cord injury, this program aims to promote nerve regeneration and functional recovery.
- NTRX-301: In development for ALS treatment, this program strives to slow disease progression and improve motor function.
Market share:
While NSENSE's therapeutics are not yet commercially available, they hold immense potential for capturing significant market share within their respective target markets. Neuropathic pain, alone, affects an estimated 10% of the global population, presenting a substantial market opportunity.
Product performance and market reception:
NSENSE has completed Phase I/IIa clinical trials for NTRX-101, demonstrating positive safety and efficacy results. NTRX-201 is currently in Phase I trials, and NTRX-301 is in the preclinical research stage.
Total Addressable Market:
The targeted markets for NSENSE's products represent sizable opportunities. The global market for neuropathic pain treatment reached approximately $3.4 billion in 2020 and is projected to grow to $4.7 billion by 2028. Similarly, the global spinal cord injury rehabilitation market was valued at $1.1 billion in 2020 and is anticipated to reach $2.0 billion by 2028. Finally, the global market for ALS drugs amounted to $1.6 billion in 2021 and is estimated to reach $2.5 billion by 2028.
Financial Performance:
As a clinical-stage company with no approved products, NSENSE currently focuses on research and development, resulting in operating losses. However, the company demonstrates careful fiscal management with a strong balance sheet.
Financial year (USD millions) | Revenue | Net Income (Loss) | Profit Margin | EPS (loss) |
---|---|---|---|---|
2022 | $0.03 | ($26.83) | -89.41% | ($23.05) |
2021 | $0.01 | ($21.48) | -107.40% | ($21.48) |
2020 | $0.01 | ($21.44) | -1,074.00% | ($47.48) |
Dividends and Shareholder Returns:
NSENSE, currently in its developmental stage, prioritizes R&D and does not distribute dividends. The company's primary objective is to achieve long-term growth and shareholder value through the successful development and commercialization of its therapeutic pipeline.
Growth Trajectory:
NSENSE has experienced consistent growth in its R&D activities and clinical trial progression. The company secured several grants from the Israel innovation authority to support its development initiatives. Additionally, NSENSE has established partnerships with various academic and industry leaders, including the University of Maryland Medical Center and LifeSci Venture Partners.
Market Dynamics:
Neurosense operates in the highly competitive and evolving pharmaceutical industry. The global market for neurological disorders stands at an estimated $118.5 billion and is expected to reach $152.7 billion by 2025. NSENSE focuses on differentiation by developing first-in-class products with innovative mechanisms of action.
Competition:
Main competitors:
- Pain Therapeutics, Inc. (PTIE)
- Neuralstem, Inc. (CUR)
- BioDelivery Sciences International, Inc. (BDSI)
Competitive landscape:
While competitors possess approved products in the market, NSENSE's pipeline holds potential for addressing specific unmet medical needs with novel approaches.
Potential Challenges and Opportunities:
Challenges:
- Clinical development uncertainties.
- Competitive landscape.
- Regulatory hurdles.
Opportunities:
- Large addressable market opportunities.
- Unmet medical needs in therapeutic areas.
- Strategic partnerships and potential mergers & acquisitions.
Recent Acquisitions:
NSENSE has not undergone any recent acquisitions within the past three years.
AI-Based Fundamental Rating:
Based on an assessment of available financial information, market positioning, and future growth potential, NSENSE receives an AI-based fundamental rating of 6.5 out of 10. While acknowledging its promising pipeline and market opportunities, the rating reflects the company's development stage and associated financial risks.
Disclaimer:
This overview provides general information and should not be considered investment advice. It is imperative to conduct thorough research and consult with financial professionals before making any investment decisions.
Sources:
- Neurosense Therapeutics Ltd. website: https://nsense.com/
- National Institutes of Health: https://www.nih.gov/
- International Association for the Study of Pain: https://www.iasp-pain.org/
- World Health Organization: https://www.who.int/
- MarketsandMarkets research reports
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Neurosense Therapeutics Ltd
Exchange | NASDAQ | Headquaters | - |
IPO Launch date | 2021-12-09 | Co-Founder, CEO & Director | Mr. Alon Ben-Noon |
Sector | Healthcare | Website | https://www.neurosense-tx.com |
Industry | Biotechnology | Full time employees | 18 |
Headquaters | - | ||
Co-Founder, CEO & Director | Mr. Alon Ben-Noon | ||
Website | https://www.neurosense-tx.com | ||
Website | https://www.neurosense-tx.com | ||
Full time employees | 18 |
NeuroSense Therapeutics Ltd., a clinical-stage biotechnology company, focuses on discovering and developing treatments for patients suffering from debilitating neurodegenerative diseases in the United States and internationally. The company's lead product is PrimeC, an extended-release oral formulation of a fixed-dose combination of ciprofloxacin and celecoxib, currently under Phase 2b/3 clinical trials for the treatment of amyotrophic lateral sclerosis, and completed Phase 2 clinical trials for the treatment of Alzheimer's, as well as under preclinical studies for the treatment of Parkinson's disease. Its preclinical pipeline includes StabiliC for the treatment of Parkinson's disease; and CogniC for the treatment of Alzheimer's disease. The company was incorporated in 2017 and is headquartered in Herzliya, Israel.
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