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Upturn stock ratingUpturn stock rating
ASND logo

Ascendis Pharma AS (ASND)

Upturn stock ratingUpturn stock rating
$125.09
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

02/03/2025: ASND (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type Stock
Historic Profit -14.15%
Avg. Invested days 39
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 02/03/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 9.10B USD
Price to earnings Ratio -
1Y Target Price 209.53
Price to earnings Ratio -
1Y Target Price 209.53
Volume (30-day avg) 391986
Beta 0.61
52 Weeks Range 111.09 - 169.37
Updated Date 04/2/2025
52 Weeks Range 111.09 - 169.37
Updated Date 04/2/2025
Dividends yield (FY) -
Basic EPS (TTM) -7.07

Analyzing Revenue: Products, Geography and Growth

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -103.97%
Operating Margin (TTM) 0.22%

Management Effectiveness

Return on Assets (TTM) -17.38%
Return on Equity (TTM) -818.43%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 9426210879
Price to Sales(TTM) 25.04
Enterprise Value 9426210879
Price to Sales(TTM) 25.04
Enterprise Value to Revenue 23.95
Enterprise Value to EBITDA -20.75
Shares Outstanding 60124700
Shares Floating 59372631
Shares Outstanding 60124700
Shares Floating 59372631
Percent Insiders 0.78
Percent Institutions 110.47

Analyst Ratings

Rating 4.73
Target Price 189.53
Buy 2
Strong Buy 12
Buy 2
Strong Buy 12
Hold 1
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Ascendis Pharma AS

stock logo

Company Overview

overview logo History and Background

Ascendis Pharma AS was founded in 2006 in Denmark and focuses on developing therapies for unmet medical needs. The company has evolved through strategic partnerships and a focus on innovative endocrinology solutions.

business area logo Core Business Areas

  • Endocrinology: Focuses on therapies for growth disorders, particularly utilizing TransCon technology for sustained release of drugs.

leadership logo Leadership and Structure

The leadership team consists of experienced executives in the pharmaceutical industry. The organizational structure is designed to support research, development, and commercialization of endocrinology therapies.

Top Products and Market Share

overview logo Key Offerings

  • Skytrofa (lonapegsomatropin-tcgd): A long-acting growth hormone for pediatric growth hormone deficiency (GHD). Competitors include Pfizer's Genotropin and Novo Nordisk's Norditropin. Skytrofa had US sales of $227.3 million in 2023.

Market Dynamics

industry overview logo Industry Overview

The endocrinology market is growing, driven by increasing prevalence of growth disorders and advancements in therapeutic options.

Positioning

Ascendis Pharma AS is positioning itself as a leader in endocrinology, particularly with its TransCon technology and long-acting hormone therapies.

Total Addressable Market (TAM)

The global growth hormone deficiency market is expected to reach billions of dollars. Ascendis Pharma AS aims to capture a significant portion of this market with Skytrofa and future products.

Upturn SWOT Analysis

Strengths

  • Innovative TransCon technology
  • Strong intellectual property portfolio
  • Successful launch of Skytrofa
  • Experienced management team

Weaknesses

  • Reliance on a single primary product (Skytrofa)
  • High R&D expenses
  • Limited commercial infrastructure compared to larger competitors
  • Dependence on regulatory approvals

Opportunities

  • Expansion into new indications for TransCon technology
  • Geographic expansion
  • Strategic partnerships
  • Development of next-generation endocrinology therapies

Threats

  • Competition from established pharmaceutical companies
  • Regulatory hurdles
  • Patent challenges
  • Pricing pressures

Competitors and Market Share

competitor logo Key Competitors

  • PFE
  • NVO

Competitive Landscape

Ascendis Pharma AS competes with established pharmaceutical companies in the endocrinology market. Its TransCon technology offers a competitive advantage, but it faces challenges in terms of scale and resources.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Ascendis Pharma AS has experienced rapid revenue growth following the approval and launch of Skytrofa.

Future Projections: Analysts project continued revenue growth driven by Skytrofa sales and potential new product approvals.

Recent Initiatives: Expansion of the Skytrofa label to younger patients and geographic expansion of its availability are key initiatives.

Summary

Ascendis Pharma AS is a growing pharmaceutical company with an innovative technology platform. It has experienced significant revenue growth but is still operating at a net loss due to high R&D spending. The company needs to successfully expand the market for Skytrofa and its pipeline. Regulatory hurdles and increasing competition represent threats to its long-term success.

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NVOratingrating

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Sources and Disclaimers

Data Sources:

  • Ascendis Pharma AS Financial Reports
  • Analyst Reports
  • Company Presentations

Disclaimers:

This analysis is for informational purposes only and should not be considered financial advice. Market data is subject to change and may not be entirely accurate.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Ascendis Pharma AS

Exchange NASDAQ
Headquaters -
IPO Launch date 2015-01-28
President, CEO, Member of Executive Board & Executive Director Mr. Jan Moller Mikkelsen
Sector Healthcare
Industry Biotechnology
Full time employees 1017
Full time employees 1017

Ascendis Pharma A/S, a biopharmaceutical company, focuses on developing TransCon-based therapies for unmet medical needs in Denmark, rest of Europe, North America, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency; and YORVIPATH, a once-daily subcutaneous injection for the treatment of adults with chronic hypoparathyroidism. It also develops a pipeline of three independent endocrinology rare disease product candidates in clinical development, as well as focuses on advancing oncology therapeutic candidates. Ascendis Pharma A/S was incorporated in 2006 and is headquartered in Hellerup, Denmark.

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