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ALEC logo ALEC
Upturn stock ratingUpturn stock rating
ALEC logo

Alector Inc (ALEC)

Upturn stock ratingUpturn stock rating
$1.16
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Time period over
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Upturn Advisory Summary

04/01/2025: ALEC (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -72.7%
Avg. Invested days 19
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 127.82M USD
Price to earnings Ratio -
1Y Target Price 4.22
Price to earnings Ratio -
1Y Target Price 4.22
Volume (30-day avg) 724526
Beta 0.65
52 Weeks Range 1.16 - 6.78
Updated Date 03/31/2025
52 Weeks Range 1.16 - 6.78
Updated Date 03/31/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.23

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -118.39%
Operating Margin (TTM) -13.37%

Management Effectiveness

Return on Assets (TTM) -16.37%
Return on Equity (TTM) -91.24%

Valuation

Trailing PE -
Forward PE 526.32
Enterprise Value -243057205
Price to Sales(TTM) 1.27
Enterprise Value -243057205
Price to Sales(TTM) 1.27
Enterprise Value to Revenue 2.38
Enterprise Value to EBITDA -8.4
Shares Outstanding 99085904
Shares Floating 73332475
Shares Outstanding 99085904
Shares Floating 73332475
Percent Insiders 13.37
Percent Institutions 83.1

Analyst Ratings

Rating 3.89
Target Price 4.59
Buy 1
Strong Buy 5
Buy 1
Strong Buy 5
Hold 1
Sell 1
Strong Sell 1
Strong Sell 1

ai summary icon Upturn AI SWOT

Alector Inc

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Company Overview

History and Background

Alector Inc. was founded in 2013 and is focused on developing therapies to treat neurodegenerative diseases by targeting the immune system. The company aims to harness the power of the brain's immune system to fight diseases like Alzheimer's and frontotemporal dementia (FTD).

Core Business Areas

  • Immuno-Neurology: Alector's primary focus is on developing immunotherapies for neurodegenerative diseases by targeting microglia and other immune cells in the brain.
  • Drug Discovery: The company employs a drug discovery platform to identify and develop novel therapeutic targets and candidates within the immuno-neurology field.

Leadership and Structure

Alector is led by a management team with experience in immunology, neuroscience, and drug development. The company has a board of directors overseeing its strategic direction.

Top Products and Market Share

Key Offerings

  • AL001: Alectoru2019s lead product candidate, AL001, is a monoclonal antibody targeting SIGLEC3, a protein expressed on microglia. It is being developed for the treatment of frontotemporal dementia (FTD) due to GRN mutations. Clinical trial data is underway. Competitors include companies developing other FTD therapies.
  • AL101: AL101 is a progranulin boosting therapy in development for frontotemporal dementia (FTD). Partnered with GSK.

Market Dynamics

Industry Overview

The neurodegenerative disease market is large and growing, driven by an aging population and increasing prevalence of diseases like Alzheimer's and Parkinson's. There is a significant unmet need for effective therapies to treat these conditions.

Positioning

Alector is positioned as a leader in the emerging field of immuno-neurology, with a focus on developing therapies that target the brain's immune system. Their competitive advantage lies in their novel approach and proprietary drug discovery platform.

Total Addressable Market (TAM)

The TAM for neurodegenerative disease treatments is estimated to be billions of dollars annually. Alector is targeting specific segments within this market, such as FTD, with significant potential for growth.

Upturn SWOT Analysis

Strengths

  • Novel immuno-neurology approach
  • Proprietary drug discovery platform
  • Experienced management team
  • Strategic partnerships

Weaknesses

  • Clinical trial risks and uncertainty
  • Reliance on strategic partnerships
  • Limited commercialized products
  • High R&D expenses

Opportunities

  • Expansion into new neurodegenerative disease areas
  • Advancement of pipeline candidates into late-stage development
  • Potential for breakthrough therapies
  • Increasing awareness of immuno-neurology

Threats

  • Clinical trial failures
  • Competition from established pharmaceutical companies
  • Regulatory hurdles
  • Intellectual property challenges

Competitors and Market Share

Key Competitors

  • BMY
  • ABBV
  • LLY
  • SNY

Competitive Landscape

Alector competes with larger pharmaceutical companies that have established positions in the neurodegenerative disease market. Its competitive advantage lies in its novel immuno-neurology approach, while its disadvantage is its smaller size and limited resources.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Alector's historical growth is primarily reflected in its pipeline development and partnerships, rather than revenue generation.

Future Projections: Future growth is dependent on the success of its clinical trials and the potential for commercialization of its drug candidates. Analyst estimates vary.

Recent Initiatives: Recent initiatives include advancing its clinical programs, expanding its research collaborations, and strengthening its intellectual property portfolio.

Summary

Alector is a biotechnology company focusing on immuno-neurology, a promising field for treating neurodegenerative diseases. They have novel pipeline products, however are in early development stage which increases risk. Success hinges on positive clinical trial outcomes and effective commercialization strategies. Partnerships are essential for financial stability and expanding reach. The company faces competition from larger, well-established pharmaceutical players.

Similar Companies

  • BMY
  • ABBV
  • LLY
  • SNY
  • GSK

Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Analyst Reports
  • Industry Publications

Disclaimers:

The information provided is for informational purposes only and should not be construed as investment advice. Investment decisions should be based on thorough research and consultation with a financial advisor.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Alector Inc

Exchange NASDAQ
Headquaters South San Francisco, CA, United States
IPO Launch date 2019-02-07
Co-Founder, CEO & Director Dr. Arnon Rosenthal Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 238
Full time employees 238

Alector, Inc., a late-stage clinical biotechnology company, develops therapies that is focused on counteracting the devastating progression of neurodegenerative diseases. The company's products under development include Latozinemab (AL001), an investigational human recombinant monoclonal antibody designed to elevate progranulin (PGRN), a protein encoded by the granulin (GRN) gene that regulates lysosomal function, neuronal survival, and inflammation in the brain. Its lead PGRN-elevating candidate is being developed for the potential treatment of frontotemporal dementia with a granulin gene mutation (FTD-GRN) which is caused by heterozygous loss-of-function (LOF) mutations in the GRN gene and results in PGRN haploinsufficiency and is in Phase 3 clinical trial. It also develops AL101/GSK4527226 that is in Phase 2 clinical trial for the treatment of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. In addition, the company's preclinical and research pipeline products include ADP037-ABC, a proprietary anti-amyloid beta (Aß) antibody paired with proprietary ABC for the treatment of AD; ADP050-ABC, a GCase replacement therapy paired with proprietary ABC for GBA gene mutation carriers with Parkinson's disease and Lewy body dementia; ADP056, a Reelin modulator designed to block tau pathology and promote synaptic function in AD; and ADP063-ABC and ADP064-ABC that are therapeutic candidates paired with proprietary ABC that target tau pathology in AD through distinct approaches. It has a strategic collaboration agreement with GlaxoSmithKline plc for the development and commercialization of progranulin-elevating monoclonal antibodies, including latozinemab and AL101 to treat neurodegenerative diseases. The company was founded in 2013 and is headquartered in South San Francisco, California.

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