
Cancel anytime
- Chart
- Upturn Summary
- Highlights
- Revenue
- Valuation
- Analyst Ratings
Upturn AI SWOT
- About


Alector Inc (ALEC)



- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- Pass (Skip investing)


(see disclosures)
- ALL
- YEAR
- MONTH
- WEEK
Upturn Advisory Summary
04/01/2025: ALEC (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -72.7% | Avg. Invested days 19 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
![]() ![]() | ![]() ![]() |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 127.82M USD | Price to earnings Ratio - | 1Y Target Price 4.22 |
Price to earnings Ratio - | 1Y Target Price 4.22 | ||
Volume (30-day avg) 724526 | Beta 0.65 | 52 Weeks Range 1.16 - 6.78 | Updated Date 03/31/2025 |
52 Weeks Range 1.16 - 6.78 | Updated Date 03/31/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.23 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -118.39% | Operating Margin (TTM) -13.37% |
Management Effectiveness
Return on Assets (TTM) -16.37% | Return on Equity (TTM) -91.24% |
Valuation
Trailing PE - | Forward PE 526.32 | Enterprise Value -243057205 | Price to Sales(TTM) 1.27 |
Enterprise Value -243057205 | Price to Sales(TTM) 1.27 | ||
Enterprise Value to Revenue 2.38 | Enterprise Value to EBITDA -8.4 | Shares Outstanding 99085904 | Shares Floating 73332475 |
Shares Outstanding 99085904 | Shares Floating 73332475 | ||
Percent Insiders 13.37 | Percent Institutions 83.1 |
Analyst Ratings
Rating 3.89 | Target Price 4.59 | Buy 1 | Strong Buy 5 |
Buy 1 | Strong Buy 5 | ||
Hold 1 | Sell 1 | Strong Sell 1 | |
Strong Sell 1 |
Upturn AI SWOT
Alector Inc

Company Overview
History and Background
Alector Inc. was founded in 2013 and is focused on developing therapies to treat neurodegenerative diseases by targeting the immune system. The company aims to harness the power of the brain's immune system to fight diseases like Alzheimer's and frontotemporal dementia (FTD).
Core Business Areas
- Immuno-Neurology: Alector's primary focus is on developing immunotherapies for neurodegenerative diseases by targeting microglia and other immune cells in the brain.
- Drug Discovery: The company employs a drug discovery platform to identify and develop novel therapeutic targets and candidates within the immuno-neurology field.
Leadership and Structure
Alector is led by a management team with experience in immunology, neuroscience, and drug development. The company has a board of directors overseeing its strategic direction.
Top Products and Market Share
Key Offerings
- AL001: Alectoru2019s lead product candidate, AL001, is a monoclonal antibody targeting SIGLEC3, a protein expressed on microglia. It is being developed for the treatment of frontotemporal dementia (FTD) due to GRN mutations. Clinical trial data is underway. Competitors include companies developing other FTD therapies.
- AL101: AL101 is a progranulin boosting therapy in development for frontotemporal dementia (FTD). Partnered with GSK.
Market Dynamics
Industry Overview
The neurodegenerative disease market is large and growing, driven by an aging population and increasing prevalence of diseases like Alzheimer's and Parkinson's. There is a significant unmet need for effective therapies to treat these conditions.
Positioning
Alector is positioned as a leader in the emerging field of immuno-neurology, with a focus on developing therapies that target the brain's immune system. Their competitive advantage lies in their novel approach and proprietary drug discovery platform.
Total Addressable Market (TAM)
The TAM for neurodegenerative disease treatments is estimated to be billions of dollars annually. Alector is targeting specific segments within this market, such as FTD, with significant potential for growth.
Upturn SWOT Analysis
Strengths
- Novel immuno-neurology approach
- Proprietary drug discovery platform
- Experienced management team
- Strategic partnerships
Weaknesses
- Clinical trial risks and uncertainty
- Reliance on strategic partnerships
- Limited commercialized products
- High R&D expenses
Opportunities
- Expansion into new neurodegenerative disease areas
- Advancement of pipeline candidates into late-stage development
- Potential for breakthrough therapies
- Increasing awareness of immuno-neurology
Threats
- Clinical trial failures
- Competition from established pharmaceutical companies
- Regulatory hurdles
- Intellectual property challenges
Competitors and Market Share
Key Competitors
- BMY
- ABBV
- LLY
- SNY
Competitive Landscape
Alector competes with larger pharmaceutical companies that have established positions in the neurodegenerative disease market. Its competitive advantage lies in its novel immuno-neurology approach, while its disadvantage is its smaller size and limited resources.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Alector's historical growth is primarily reflected in its pipeline development and partnerships, rather than revenue generation.
Future Projections: Future growth is dependent on the success of its clinical trials and the potential for commercialization of its drug candidates. Analyst estimates vary.
Recent Initiatives: Recent initiatives include advancing its clinical programs, expanding its research collaborations, and strengthening its intellectual property portfolio.
Summary
Alector is a biotechnology company focusing on immuno-neurology, a promising field for treating neurodegenerative diseases. They have novel pipeline products, however are in early development stage which increases risk. Success hinges on positive clinical trial outcomes and effective commercialization strategies. Partnerships are essential for financial stability and expanding reach. The company faces competition from larger, well-established pharmaceutical players.
Similar Companies
- BMY
- ABBV
- LLY
- SNY
- GSK
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
- Industry Publications
Disclaimers:
The information provided is for informational purposes only and should not be construed as investment advice. Investment decisions should be based on thorough research and consultation with a financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Alector Inc
Exchange NASDAQ | Headquaters South San Francisco, CA, United States | ||
IPO Launch date 2019-02-07 | Co-Founder, CEO & Director Dr. Arnon Rosenthal Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 238 | Website https://www.alector.com |
Full time employees 238 | Website https://www.alector.com |
Alector, Inc., a late-stage clinical biotechnology company, develops therapies that is focused on counteracting the devastating progression of neurodegenerative diseases. The company's products under development include Latozinemab (AL001), an investigational human recombinant monoclonal antibody designed to elevate progranulin (PGRN), a protein encoded by the granulin (GRN) gene that regulates lysosomal function, neuronal survival, and inflammation in the brain. Its lead PGRN-elevating candidate is being developed for the potential treatment of frontotemporal dementia with a granulin gene mutation (FTD-GRN) which is caused by heterozygous loss-of-function (LOF) mutations in the GRN gene and results in PGRN haploinsufficiency and is in Phase 3 clinical trial. It also develops AL101/GSK4527226 that is in Phase 2 clinical trial for the treatment of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. In addition, the company's preclinical and research pipeline products include ADP037-ABC, a proprietary anti-amyloid beta (Aß) antibody paired with proprietary ABC for the treatment of AD; ADP050-ABC, a GCase replacement therapy paired with proprietary ABC for GBA gene mutation carriers with Parkinson's disease and Lewy body dementia; ADP056, a Reelin modulator designed to block tau pathology and promote synaptic function in AD; and ADP063-ABC and ADP064-ABC that are therapeutic candidates paired with proprietary ABC that target tau pathology in AD through distinct approaches. It has a strategic collaboration agreement with GlaxoSmithKline plc for the development and commercialization of progranulin-elevating monoclonal antibodies, including latozinemab and AL101 to treat neurodegenerative diseases. The company was founded in 2013 and is headquartered in South San Francisco, California.
Note: This website is maintained by Upturn Corporation, which is an investment adviser registered with the U.S. Securities and Exchange Commission. Such registration does not imply a certain level of skill or training. Investing in securities has risks. Past performance is no guarantee of future returns. No assurance is provided as to any particular investment return, and you may lose money using our services. You are strongly advised to consult appropriate counsel before making any investments in companies you learn about through our services. You should obtain appropriate legal, tax, investment, accounting, and other advice that takes into account your investment portfolio and overall financial situation. You are solely responsible for conducting due diligence on a potential investment. We do not affect trades for you. You will select your own broker through which to transact. Investments are not FDIC insured, they are not guaranteed, and they may lose value. Please see the Privacy Policy, Terms of Use, and Disclosure for more information.