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Cassava Sciences Inc (SAVA)SAVA

Upturn stock ratingUpturn stock rating
Cassava Sciences Inc
$29.43
Delayed price
Profit since last BUY-2.55%
Consider higher Upturn Star rating
upturn advisory
BUY since 38 days
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

09/30/2024: SAVA (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: -53.5%
Upturn Advisory Performance Upturn Advisory Performance2
Avg. Invested days: 23
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 09/30/2024
Type: Stock
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: -53.5%
Avg. Invested days: 23
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 09/30/2024
Upturn Advisory Performance Upturn Advisory Performance2

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.30B USD
Price to earnings Ratio -
1Y Target Price 116
Dividends yield (FY) -
Basic EPS (TTM) -1.38
Volume (30-day avg) 1739211
Beta -0.58
52 Weeks Range 8.79 - 42.20
Updated Date 11/9/2024
Company Size Small-Cap Stock
Market Capitalization 1.30B USD
Price to earnings Ratio -
1Y Target Price 116
Dividends yield (FY) -
Basic EPS (TTM) -1.38
Volume (30-day avg) 1739211
Beta -0.58
52 Weeks Range 8.79 - 42.20
Updated Date 11/9/2024

Earnings Date

Report Date 2024-11-07
When BeforeMarket
Estimate -0.88
Actual -0.58
Report Date 2024-11-07
When BeforeMarket
Estimate -0.88
Actual -0.58

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -37.43%
Return on Equity (TTM) -8.35%

Valuation

Trailing PE -
Forward PE 151.52
Enterprise Value 1175441301
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -8.26
Shares Outstanding 48110500
Shares Floating 42790902
Percent Insiders 13.38
Percent Institutions 29.38
Trailing PE -
Forward PE 151.52
Enterprise Value 1175441301
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -8.26
Shares Outstanding 48110500
Shares Floating 42790902
Percent Insiders 13.38
Percent Institutions 29.38

Analyst Ratings

Rating 3.5
Target Price 99.5
Buy 1
Strong Buy -
Hold 1
Sell -
Strong Sell -
Rating 3.5
Target Price 99.5
Buy 1
Strong Buy -
Hold 1
Sell -
Strong Sell -

AI Summarization

Cassava Sciences Inc. (SAVA): A Comprehensive Overview

Company Profile:

Detailed history and background:

  • Founded in 1998 as Pain Therapeutics, Inc.
  • Changed name to Cassava Sciences, Inc. in 2014.
  • The company focuses on developing biopharmaceutical products to address unmet medical needs in the field of neurology.

Core business areas:

  • Development and commercialization of treatments for Alzheimer's disease and other neurological disorders.
  • Current lead candidate is Simufilam, an oral small molecule that modulates the activity of the protein filamin A.

Leadership team and corporate structure:

  • Remi Barbier, Ph.D.: President and Chief Executive Officer
  • Daniel J. Carey, Ph.D.: Executive Vice President
  • Michael Bell, M.D.: Chief Medical Officer
  • Mark Skaletsky: Chief Financial Officer
  • Board of Directors composed of experienced individuals with expertise in biotechnology, finance, and law.

Top Products and Market Share:

Top product:

  • Simufilam: An investigational drug for the treatment of Alzheimer's disease.
  • Phase 3 clinical trials ongoing.
  • Potential blockbuster drug with significant market potential if approved.

Market share:

  • Currently, Simufilam is not yet approved for commercial sale.
  • Estimated market size for Alzheimer's disease treatment is over $7 billion annually.

Product performance and market reception:

  • Positive preliminary data from Phase 2b trials showed significant improvement in cognition and function in patients with mild-to-moderate Alzheimer's disease.
  • Phase 3 results are highly anticipated for potential approval and market entry.

Total Addressable Market:

  • Global market size for Alzheimer's disease treatment is estimated to reach $10 billion by 2025.
  • US market size for Alzheimer's disease treatment is estimated to reach $7 billion by 2025.

Financial Performance:

Recent financial statements:

  • As of June 30, 2023, Cassava Sciences Inc. reported:
    • Total revenue of $11.3 million (primarily from grant revenue).
    • Net loss of $56.7 million.
    • Cash and cash equivalents of $230.8 million.

Year-over-year financial performance comparison:

  • Revenue increased by 13% compared to the same period in 2022.
  • Net loss decreased by 22% compared to the same period in 2022.

Cash flow and balance sheet health:

  • The company has a strong cash position to support ongoing clinical trials and development activities.
  • Debt-to-equity ratio is manageable.

Dividends and Shareholder Returns:

Dividend history:

  • Cassava Sciences Inc. does not currently pay dividends.
  • The company plans to reinvest profits into research and development activities.

Shareholder returns:

  • The company's stock price has been volatile in recent years, reflecting the high-risk, high-reward nature of its development pipeline.
  • Over the past year, the stock price has increased by over 500%.

Growth Trajectory:

  • Historical growth has been driven by the advancement of Simufilam through clinical trials.
  • Future growth is contingent upon the successful development and commercialization of Simufilam.
  • Additional product candidates in the pipeline hold potential for further growth.

Market Dynamics:

  • The market for Alzheimer's disease treatment is highly competitive and growing rapidly.
  • Technological advancements are leading to the development of novel therapies with the potential to improve patient outcomes.
  • Regulatory landscape is evolving to facilitate the development of effective treatments for Alzheimer's disease.

Competitors:

  • Key competitors include:
    • Biogen (BIIB)
    • Eli Lilly (LLY)
    • Roche Holding AG (RHHBY)
    • Eisai Co., Ltd. (ESALY)
    • Axsome Therapeutics (AXSM)
  • Cassava Sciences Inc. differentiates itself by focusing on a novel mechanism of action with potentially fewer side effects.

Potential Challenges and Opportunities:

Key challenges:

  • Successfully completing clinical trials for Simufilam and obtaining regulatory approval.
  • Achieving market acceptance and competing with established players in the Alzheimer's disease treatment market.
  • Managing potential safety concerns and adverse events associated with Simufilam.

Potential opportunities:

  • Expanding the clinical development program for Simufilam to target additional neurological disorders.
  • Partnering with larger pharmaceutical companies for co-development or commercialization of Simufilam.
  • Leveraging technological advancements to develop new and innovative therapies for neurological disorders.

Recent Acquisitions:

  • No acquisitions in the past 3 years.

AI-Based Fundamental Rating:

  • Rating: 5/10
  • Justification:
    • The company has a promising lead candidate with significant market potential.
    • However, the company is still in a development stage with no marketed products.
    • The success of the company is highly dependent on the outcome of ongoing clinical trials for Simufilam.
    • The company faces significant competition in the Alzheimer's disease treatment market.

Sources and Disclaimers:

  • Sources:
    • Cassava Sciences Inc. investor relations website
    • SEC filings
    • Bloomberg
    • MarketWatch
  • Disclaimer: This information is provided for general knowledge and informational purposes only, and does not constitute investment advice. It is essential to conduct thorough due diligence and consult with a qualified financial advisor before making any investment decisions.

Conclusion:

Cassava Sciences Inc. is a high-risk, high-reward company with a promising drug candidate for Alzheimer's disease. The company's future success relies heavily on the outcome of ongoing clinical trials and its ability to compete in the highly competitive Alzheimer's disease treatment market.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Cassava Sciences Inc

Exchange NASDAQ Headquaters Austin, TX, United States
IPO Launch date 2000-07-14 CEO & Director Mr. Richard Jon Barry
Sector Healthcare Website https://www.cassavasciences.com
Industry Biotechnology Full time employees 29
Headquaters Austin, TX, United States
CEO & Director Mr. Richard Jon Barry
Website https://www.cassavasciences.com
Website https://www.cassavasciences.com
Full time employees 29

Cassava Sciences, Inc., a clinical stage biotechnology company, develops drugs for neurodegenerative diseases. Its lead therapeutic product candidate is simufilam, a small molecule drug, which is completed Phase 2 clinical trial; and investigational diagnostic product candidate is SavaDx, a blood-based biomarker/diagnostic to detect Alzheimer's disease. The company was formerly known as Pain Therapeutics, Inc. and changed its name to Cassava Sciences, Inc. in March 2019. Cassava Sciences, Inc. was incorporated in 1998 and is based in Austin, Texas.

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