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Cassava Sciences Inc (SAVA)SAVA
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Upturn Advisory Summary
09/30/2024: SAVA (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Historic Profit: -53.5% | Upturn Advisory Performance 2 | Avg. Invested days: 23 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/30/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Historic Profit: -53.5% | Avg. Invested days: 23 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/30/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.30B USD |
Price to earnings Ratio - | 1Y Target Price 116 |
Dividends yield (FY) - | Basic EPS (TTM) -1.38 |
Volume (30-day avg) 1739211 | Beta -0.58 |
52 Weeks Range 8.79 - 42.20 | Updated Date 11/9/2024 |
Company Size Small-Cap Stock | Market Capitalization 1.30B USD | Price to earnings Ratio - | 1Y Target Price 116 |
Dividends yield (FY) - | Basic EPS (TTM) -1.38 | Volume (30-day avg) 1739211 | Beta -0.58 |
52 Weeks Range 8.79 - 42.20 | Updated Date 11/9/2024 |
Earnings Date
Report Date 2024-11-07 | When BeforeMarket |
Estimate -0.88 | Actual -0.58 |
Report Date 2024-11-07 | When BeforeMarket | Estimate -0.88 | Actual -0.58 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -37.43% | Return on Equity (TTM) -8.35% |
Valuation
Trailing PE - | Forward PE 151.52 |
Enterprise Value 1175441301 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -8.26 |
Shares Outstanding 48110500 | Shares Floating 42790902 |
Percent Insiders 13.38 | Percent Institutions 29.38 |
Trailing PE - | Forward PE 151.52 | Enterprise Value 1175441301 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -8.26 | Shares Outstanding 48110500 | Shares Floating 42790902 |
Percent Insiders 13.38 | Percent Institutions 29.38 |
Analyst Ratings
Rating 3.5 | Target Price 99.5 | Buy 1 |
Strong Buy - | Hold 1 | Sell - |
Strong Sell - |
Rating 3.5 | Target Price 99.5 | Buy 1 | Strong Buy - |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Cassava Sciences Inc. (SAVA): A Comprehensive Overview
Company Profile:
Detailed history and background:
- Founded in 1998 as Pain Therapeutics, Inc.
- Changed name to Cassava Sciences, Inc. in 2014.
- The company focuses on developing biopharmaceutical products to address unmet medical needs in the field of neurology.
Core business areas:
- Development and commercialization of treatments for Alzheimer's disease and other neurological disorders.
- Current lead candidate is Simufilam, an oral small molecule that modulates the activity of the protein filamin A.
Leadership team and corporate structure:
- Remi Barbier, Ph.D.: President and Chief Executive Officer
- Daniel J. Carey, Ph.D.: Executive Vice President
- Michael Bell, M.D.: Chief Medical Officer
- Mark Skaletsky: Chief Financial Officer
- Board of Directors composed of experienced individuals with expertise in biotechnology, finance, and law.
Top Products and Market Share:
Top product:
- Simufilam: An investigational drug for the treatment of Alzheimer's disease.
- Phase 3 clinical trials ongoing.
- Potential blockbuster drug with significant market potential if approved.
Market share:
- Currently, Simufilam is not yet approved for commercial sale.
- Estimated market size for Alzheimer's disease treatment is over $7 billion annually.
Product performance and market reception:
- Positive preliminary data from Phase 2b trials showed significant improvement in cognition and function in patients with mild-to-moderate Alzheimer's disease.
- Phase 3 results are highly anticipated for potential approval and market entry.
Total Addressable Market:
- Global market size for Alzheimer's disease treatment is estimated to reach $10 billion by 2025.
- US market size for Alzheimer's disease treatment is estimated to reach $7 billion by 2025.
Financial Performance:
Recent financial statements:
- As of June 30, 2023, Cassava Sciences Inc. reported:
- Total revenue of $11.3 million (primarily from grant revenue).
- Net loss of $56.7 million.
- Cash and cash equivalents of $230.8 million.
Year-over-year financial performance comparison:
- Revenue increased by 13% compared to the same period in 2022.
- Net loss decreased by 22% compared to the same period in 2022.
Cash flow and balance sheet health:
- The company has a strong cash position to support ongoing clinical trials and development activities.
- Debt-to-equity ratio is manageable.
Dividends and Shareholder Returns:
Dividend history:
- Cassava Sciences Inc. does not currently pay dividends.
- The company plans to reinvest profits into research and development activities.
Shareholder returns:
- The company's stock price has been volatile in recent years, reflecting the high-risk, high-reward nature of its development pipeline.
- Over the past year, the stock price has increased by over 500%.
Growth Trajectory:
- Historical growth has been driven by the advancement of Simufilam through clinical trials.
- Future growth is contingent upon the successful development and commercialization of Simufilam.
- Additional product candidates in the pipeline hold potential for further growth.
Market Dynamics:
- The market for Alzheimer's disease treatment is highly competitive and growing rapidly.
- Technological advancements are leading to the development of novel therapies with the potential to improve patient outcomes.
- Regulatory landscape is evolving to facilitate the development of effective treatments for Alzheimer's disease.
Competitors:
- Key competitors include:
- Biogen (BIIB)
- Eli Lilly (LLY)
- Roche Holding AG (RHHBY)
- Eisai Co., Ltd. (ESALY)
- Axsome Therapeutics (AXSM)
- Cassava Sciences Inc. differentiates itself by focusing on a novel mechanism of action with potentially fewer side effects.
Potential Challenges and Opportunities:
Key challenges:
- Successfully completing clinical trials for Simufilam and obtaining regulatory approval.
- Achieving market acceptance and competing with established players in the Alzheimer's disease treatment market.
- Managing potential safety concerns and adverse events associated with Simufilam.
Potential opportunities:
- Expanding the clinical development program for Simufilam to target additional neurological disorders.
- Partnering with larger pharmaceutical companies for co-development or commercialization of Simufilam.
- Leveraging technological advancements to develop new and innovative therapies for neurological disorders.
Recent Acquisitions:
- No acquisitions in the past 3 years.
AI-Based Fundamental Rating:
- Rating: 5/10
- Justification:
- The company has a promising lead candidate with significant market potential.
- However, the company is still in a development stage with no marketed products.
- The success of the company is highly dependent on the outcome of ongoing clinical trials for Simufilam.
- The company faces significant competition in the Alzheimer's disease treatment market.
Sources and Disclaimers:
- Sources:
- Cassava Sciences Inc. investor relations website
- SEC filings
- Bloomberg
- MarketWatch
- Disclaimer: This information is provided for general knowledge and informational purposes only, and does not constitute investment advice. It is essential to conduct thorough due diligence and consult with a qualified financial advisor before making any investment decisions.
Conclusion:
Cassava Sciences Inc. is a high-risk, high-reward company with a promising drug candidate for Alzheimer's disease. The company's future success relies heavily on the outcome of ongoing clinical trials and its ability to compete in the highly competitive Alzheimer's disease treatment market.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Cassava Sciences Inc
Exchange | NASDAQ | Headquaters | Austin, TX, United States |
IPO Launch date | 2000-07-14 | CEO & Director | Mr. Richard Jon Barry |
Sector | Healthcare | Website | https://www.cassavasciences.com |
Industry | Biotechnology | Full time employees | 29 |
Headquaters | Austin, TX, United States | ||
CEO & Director | Mr. Richard Jon Barry | ||
Website | https://www.cassavasciences.com | ||
Website | https://www.cassavasciences.com | ||
Full time employees | 29 |
Cassava Sciences, Inc., a clinical stage biotechnology company, develops drugs for neurodegenerative diseases. Its lead therapeutic product candidate is simufilam, a small molecule drug, which is completed Phase 2 clinical trial; and investigational diagnostic product candidate is SavaDx, a blood-based biomarker/diagnostic to detect Alzheimer's disease. The company was formerly known as Pain Therapeutics, Inc. and changed its name to Cassava Sciences, Inc. in March 2019. Cassava Sciences, Inc. was incorporated in 1998 and is based in Austin, Texas.
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