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Actuate Therapeutics, Inc. Common stock (ACTU)



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Upturn Advisory Summary
04/04/2025: ACTU (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -31.27% | Avg. Invested days 25 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 152.89M USD | Price to earnings Ratio - | 1Y Target Price - |
Price to earnings Ratio - | 1Y Target Price - | ||
Volume (30-day avg) 33996 | Beta - | 52 Weeks Range 5.51 - 11.73 | Updated Date 04/3/2025 |
52 Weeks Range 5.51 - 11.73 | Updated Date 04/3/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.85 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) - | Return on Equity (TTM) - |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 158213735 | Price to Sales(TTM) - |
Enterprise Value 158213735 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding 19111600 | Shares Floating 546301 |
Shares Outstanding 19111600 | Shares Floating 546301 | ||
Percent Insiders 19.1 | Percent Institutions 52.21 |
Analyst Ratings
Rating - | Target Price - | Buy - | Strong Buy - |
Buy - | Strong Buy - | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Actuate Therapeutics, Inc. Common stock
Company Overview
History and Background
Actuate Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for cancers that have become resistant to standard treatments. Details regarding the founding year and early milestones are currently unavailable publicly. They primarily focus on developing kinase inhibitors.
Core Business Areas
- Drug Development: Actuate focuses on the research and development of novel small molecule therapeutics for cancer treatment, specifically targeting kinases involved in cancer progression.
Leadership and Structure
Information on Actuate Therapeutics, Inc. Common stock's leadership team and organizational structure is not available at the time of this analysis.
Top Products and Market Share
Key Offerings
- 9-ING-41: Actuate's lead drug candidate, 9-ING-41, is a selective GSK-3u03b2 inhibitor. It is currently in clinical trials for various cancers, including metastatic pancreatic cancer, ovarian cancer and acute myeloid leukemia. Market share data is unavailable due to being in clinical development. Potential competitors depend on the specific cancer indication and could include companies developing similar targeted therapies, chemotherapy drugs, or immunotherapies.
Market Dynamics
Industry Overview
The biopharmaceutical industry is highly competitive and innovative, with a constant need for new and effective cancer therapies. The market is driven by an aging population, increasing cancer incidence, and advancements in targeted therapies.
Positioning
Actuate Therapeutics, Inc. aims to establish itself as a leader in developing therapies for resistant cancers by targeting GSK-3u03b2. Its success depends on the clinical trial outcomes of 9-ING-41 and its ability to secure funding and partnerships.
Total Addressable Market (TAM)
The TAM for cancer therapies is substantial, estimated to be hundreds of billions of dollars globally. Actuate's positioning depends on the specific cancers 9-ING-41 targets and its efficacy compared to existing treatments.
Upturn SWOT Analysis
Strengths
- Novel drug target (GSK-3u03b2)
- Clinical-stage asset (9-ING-41)
- Potential for addressing unmet needs in resistant cancers
Weaknesses
- Limited financial resources
- Dependence on clinical trial success
- Single lead product
Opportunities
- Partnerships with larger pharmaceutical companies
- Expansion of 9-ING-41 to additional cancer indications
- Positive clinical trial results leading to accelerated approval
Threats
- Clinical trial failures
- Competition from other drug developers
- Regulatory hurdles
Competitors and Market Share
Key Competitors
- LLY
- MRK
- BMY
Competitive Landscape
Actuate Therapeutics, Inc. faces significant competition from established pharmaceutical companies with greater resources and broader pipelines. Its success depends on demonstrating the unique efficacy of 9-ING-41 in addressing resistant cancers.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth trends are not available due to limited public data.
Future Projections: Future growth projections are unavailable due to the company's stage of development.
Recent Initiatives: Actuate's recent initiatives focus on advancing the clinical development of 9-ING-41 and securing funding for future trials.
Summary
Actuate Therapeutics, Inc. is a clinical-stage biopharmaceutical company with a novel drug candidate targeting GSK-3u03b2 for cancer treatment. While it holds promise in addressing unmet needs in resistant cancers, it faces challenges related to clinical trial success, funding, and competition. The company's future is heavily dependent on the successful development and commercialization of 9-ING-41. Lack of publicly available financial data and established market presence presents increased risk. Securing strategic partnerships is crucial for sustained growth.
Similar Companies

BMY

Bristol-Myers Squibb Company



BMY

Bristol-Myers Squibb Company

LLY

Eli Lilly and Company



LLY

Eli Lilly and Company

MRK

Merck & Company Inc



MRK

Merck & Company Inc
Sources and Disclaimers
Data Sources:
- Company website
- Clinical trial databases
- Industry reports
Disclaimers:
This analysis is based on limited publicly available information and is subject to change. It is not financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Actuate Therapeutics, Inc. Common stock
Exchange NASDAQ | Headquaters Fort Worth, TX, United States | ||
IPO Launch date 2024-08-13 | CEO - | ||
Sector Healthcare | Industry Biotechnology | Full time employees 10 | Website https://actuatetherapeutics.com |
Full time employees 10 | Website https://actuatetherapeutics.com |
Actuate Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing therapies for the treatment of cancers. Its lead product candidate, Elraglusib Injection, is a novel glycogen synthase kinase-3 inhibitor to treat metastatic pancreatic ductal adenocarcinoma. The company also develops Elraglusib for the treatment of Ewing sarcoma, metastatic melanoma, and colorectal cancer. It has license agreements with the University of Illinois-Chicago and Northwestern University for the use of GSK-3B inhibitor. The company was formerly known as Apotheca Therapeutics, Inc. and changed its name to Actuate Therapeutics, Inc. in October 2015. Actuate Therapeutics, Inc. was incorporated in 2015 and is based in Fort Worth, Texas.
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