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ACRS
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Aclaris Therapeutics Inc (ACRS)

Upturn stock ratingUpturn stock rating
$1.62
Delayed price
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PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
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Upturn Advisory Summary

03/27/2025: ACRS (2-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

AI Based Fundamental Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type Stock
Historic Profit 4.95%
Avg. Invested days 32
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 03/27/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 171.96M USD
Price to earnings Ratio -
1Y Target Price 9.83
Price to earnings Ratio -
1Y Target Price 9.83
Volume (30-day avg) 963497
Beta 0.5
52 Weeks Range 0.95 - 5.17
Updated Date 03/30/2025
52 Weeks Range 0.95 - 5.17
Updated Date 03/30/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.71

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -152.75%

Management Effectiveness

Return on Assets (TTM) -15.72%
Return on Equity (TTM) -84.46%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 53275793
Price to Sales(TTM) 9.19
Enterprise Value 53275793
Price to Sales(TTM) 9.19
Enterprise Value to Revenue 2.85
Enterprise Value to EBITDA 0.28
Shares Outstanding 108148000
Shares Floating 66075457
Shares Outstanding 108148000
Shares Floating 66075457
Percent Insiders 2.65
Percent Institutions 82.48

Analyst Ratings

Rating 4.14
Target Price 10
Buy 2
Strong Buy 3
Buy 2
Strong Buy 3
Hold 2
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Aclaris Therapeutics Inc

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Company Overview

History and Background

Aclaris Therapeutics, Inc. was founded in 2012. It's a biopharmaceutical company focused on developing novel treatments for immuno-inflammatory diseases. It has evolved from focusing solely on dermatology to a broader range of immune-related conditions.

Core Business Areas

  • Immun-inflammatory disease segment: Developing novel treatments for immuno-inflammatory diseases. Focusing on oral and topical treatments targeting key pathways in immuno-inflammatory diseases.

Leadership and Structure

The leadership team includes Neal Walker as President and CEO. The company has a board of directors overseeing its operations.

Top Products and Market Share

Key Offerings

  • Zunseogep: Aclaris Therapeutics is developing Zunseogep, a novel oral MK2 inhibitor, as a potential treatment for hidradenitis suppurativa (HS) and other immuno-inflammatory diseases. Specific market share data for Zunseogep is currently unavailable as it is in clinical development. Competitors depend on indications and success. Competitors in Hidradenitis Suppurativa include AbbVie (Humira), Novartis (Cosentyx), and various companies developing new therapies.

Market Dynamics

Industry Overview

The biopharmaceutical industry is highly competitive and innovative. There is a growing demand for treatments for immuno-inflammatory diseases.

Positioning

Aclaris Therapeutics is positioned as a developer of novel treatments for immuno-inflammatory diseases, focusing on unmet medical needs. Its competitive advantage lies in its focus on novel targets and oral therapies.

Total Addressable Market (TAM)

The total addressable market (TAM) for immuno-inflammatory disease treatments is substantial, estimated to be worth tens of billions of dollars globally, and is projected to keep growing. Aclaris is positioned to tap into a portion of this TAM with their focus on novel therapies and new routes of administration.

Upturn SWOT Analysis

Strengths

  • Novel therapeutic candidates
  • Focus on immuno-inflammatory diseases
  • Experienced management team
  • Oral and topical drug delivery platforms

Weaknesses

  • Limited product portfolio
  • Reliance on clinical trial success
  • Limited commercialization experience
  • Dependence on financing

Opportunities

  • Expansion of pipeline
  • Partnerships and collaborations
  • Expansion into new indications
  • Potential for market exclusivity

Threats

  • Competition from established players
  • Regulatory hurdles
  • Clinical trial failures
  • Patent expirations

Competitors and Market Share

Key Competitors

  • ABBV
  • NVS
  • LLY

Competitive Landscape

Aclaris Therapeutics faces competition from larger, more established pharmaceutical companies with greater resources. Its advantages include its focus on novel therapies and oral formulations. Disadvantages include its limited product portfolio and dependence on clinical trial success.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical growth trends are dependent on revenue from marketed products and the progress of the drug pipeline. Aclaris Therapeutics has shifted its focus over time, which impacts historical growth analysis.

Future Projections: Future growth projections depend on clinical trial outcomes and regulatory approvals of its pipeline candidates. Analyst estimates are not readily available in this structured format.

Recent Initiatives: Recent initiatives include the development of Zunseogep and other pipeline candidates for immuno-inflammatory diseases.

Summary

Aclaris Therapeutics is a biopharmaceutical company with a focus on immuno-inflammatory diseases and novel therapeutics. Its strength lies in its innovative pipeline and oral drug delivery platform. Its weaknesses include its limited portfolio and dependence on clinical trials. The company needs to successfully develop and commercialize its lead product candidates to drive growth. Aclaris is a risky company that will need great science and great execution to survive, thrive and grow.

Similar Companies

  • ABBV
  • NVS
  • LLY
  • BMY

Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Industry reports
  • Analyst reports (limited access)

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Market share data is estimated and may not be precise. The AI rating is subjective and based on the available information.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Aclaris Therapeutics Inc

Exchange NASDAQ
Headquaters Wayne, PA, United States
IPO Launch date 2015-10-07
Co-Founder, CEO & Chairman Dr. Neal S. Walker D.O., M.D.
Sector Healthcare
Industry Diagnostics & Research
Full time employees 61
Full time employees 61

Aclaris Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of novel drug candidates for immune-inflammatory diseases in the United States. It operates through two segments, Therapeutics and Contract Research. The Therapeutics segment is involved in identifying and developing therapies to address significant unmet needs for immuno-inflammatory diseases. Its Contract Research segment provides laboratory services. The company also develops ATI-1777, a soft JAK 1/3 inhibitor in Phase 2b trial for the treatment of atopic dermatitis and other dermatologic conditions; Bosakitug (ATI-045), an anti-TSLP monoclonal antibody in Phase 2a trial to treat moderate to severe atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps, and moderate to severe chronic obstructive pulmonary disease; ATI-2138, an oral covalent inhibitor of ITK and JAK3 inhibitor in Phase 2a trial for the treatment for T cell-mediated autoimmune diseases; Zunsemetinib (ATI-450), a mitogen-activated protein kinase-activated protein kinase 2 inhibitor under Phase 1b/2 trials for the treatment of metastatic breast cancer and pancreatic ductal adenocarcinoma; and ATI-052, a humanized anti-TSLP and anti-IL4R bispecific antibody in preclinical stage to treat various atopic, immunologic, and respiratory diseases, as well as an ITK selective inhibitor candidate for the treatment of autoimmune diseases. Aclaris Therapeutics, Inc. was incorporated in 2012 and is headquartered in Wayne, Pennsylvania.

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