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TG Therapeutics Inc (TGTX)TGTX
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Upturn Advisory Summary
09/18/2024: TGTX (4-star) is a STRONG-BUY. BUY since 23 days. Profits (14.36%). Updated daily EoD!
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Strong Buy |
Profit: 242.42% | Upturn Advisory Performance 5 | Avg. Invested days: 39 |
Profits based on simulation | Stock Returns Performance 5 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Strong Buy |
Profit: 242.42% | Avg. Invested days: 39 |
Upturn Star Rating | Stock Returns Performance 5 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 5 |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 3.91B USD |
Price to earnings Ratio 37.13 | 1Y Target Price 34.29 |
Dividends yield (FY) - | Basic EPS (TTM) 0.68 |
Volume (30-day avg) 3494704 | Beta 2.21 |
52 Weeks Range 6.46 - 26.41 | Updated Date 09/19/2024 |
Company Size Mid-Cap Stock | Market Capitalization 3.91B USD | Price to earnings Ratio 37.13 | 1Y Target Price 34.29 |
Dividends yield (FY) - | Basic EPS (TTM) 0.68 | Volume (30-day avg) 3494704 | Beta 2.21 |
52 Weeks Range 6.46 - 26.41 | Updated Date 09/19/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin 27.6% | Operating Margin (TTM) 12% |
Management Effectiveness
Return on Assets (TTM) 20.47% | Return on Equity (TTM) 87.78% |
Revenue by Products
Revenue by Products - Current and Previous Year
Revenue by Geography
Valuation
Trailing PE 37.13 | Forward PE 42.73 |
Enterprise Value 3804570209 | Price to Sales(TTM) 11.27 |
Enterprise Value to Revenue 10.97 | Enterprise Value to EBITDA 35.05 |
Shares Outstanding 154823008 | Shares Floating 133474909 |
Percent Insiders 9.59 | Percent Institutions 61.04 |
Trailing PE 37.13 | Forward PE 42.73 | Enterprise Value 3804570209 | Price to Sales(TTM) 11.27 |
Enterprise Value to Revenue 10.97 | Enterprise Value to EBITDA 35.05 | Shares Outstanding 154823008 | Shares Floating 133474909 |
Percent Insiders 9.59 | Percent Institutions 61.04 |
Analyst Ratings
Rating 4.22 | Target Price 26.61 | Buy 2 |
Strong Buy 5 | Hold 1 | Sell 1 |
Strong Sell - |
Rating 4.22 | Target Price 26.61 | Buy 2 | Strong Buy 5 |
Hold 1 | Sell 1 | Strong Sell - |
AI Summarization
TG Therapeutics Inc.: A Comprehensive Overview
Company Profile:
Detailed history and background: TG Therapeutics Inc. (NASDAQ: TGTX) is a biopharmaceutical company focused on the development and commercialization of novel treatments for B-cell malignancies and autoimmune diseases. Founded in 2007 and headquartered in New York City, TG Therapeutics has a rich history of research and development, leading to the approval of multiple innovative therapies.
Core business areas: TG Therapeutics focuses on two primary areas:
- B-cell malignancies: The company develops and markets Ukoniq (umbralisib), a PI3K delta inhibitor for the treatment of relapsed or refractory marginal zone lymphoma (MZL) and follicular lymphoma (FL).
- Autoimmune diseases: TG Therapeutics is currently in the late stages of development for ublituximab, an anti-CD20 monoclonal antibody for the treatment of multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD).
Leadership team and corporate structure: TG Therapeutics boasts a seasoned leadership team with extensive experience in the pharmaceutical industry. Michael S. Weiss is the Chairman and CEO, leading the company's strategic direction and operations. The company operates with a decentralized structure, with research and development, manufacturing, and commercialization activities spread across multiple locations in the United States and Europe.
Top Products and Market Share:
Top Products:
- Ukoniq (umbralisib): This PI3K delta inhibitor is approved for the treatment of relapsed or refractory MZL and FL. It achieved a peak market share of 3.7% in the second quarter of 2023 in the US MZL market.
- Ublituximab: This anti-CD20 monoclonal antibody is currently undergoing Phase 3 clinical trials for MS and NMOSD.
Market share: Ukoniq holds a 3.7% market share in the US MZL market, competing against other PI3K delta inhibitors like Gilead's Zydelig (idelalisib) and Verastem's Copiktra (duvelisib).
Product performance and market reception: Ukoniq has demonstrated promising clinical data and received generally positive market reception. However, its market share growth has been slower than anticipated due to the competitive landscape and limited patient population.
Total Addressable Market:
TG Therapeutics operates within the global market for B-cell malignancies and autoimmune diseases.
- B-cell malignancies: The global B-cell malignancies market is estimated to reach USD 35.7 billion by 2027, with MZL and FL representing a significant segment.
- Autoimmune diseases: The global autoimmune diseases market is projected to reach USD 216.3 billion by 2028, with MS and NMOSD being major contributors.
Financial Performance:
Recent financial statements: TG Therapeutics reported USD 73.3 million in revenue for the first half of 2023, primarily driven by Ukoniq sales. However, the company is yet to achieve profitability, reporting a net loss of USD 119.3 million for the same period.
Financial performance comparison: Year-over-year revenue growth has been encouraging, with a 43% increase in Q2 2023 compared to Q2 2022. However, the company's net loss has also widened due to increased operating expenses.
Cash flow statements and balance sheet health: TG Therapeutics has a healthy cash position of USD 611.4 million as of June 30, 2023. However, the company's cash burn rate remains high due to ongoing clinical trials and commercialization efforts.
Dividends and Shareholder Returns:
Dividend History: TG Therapeutics does not currently pay dividends to shareholders.
Shareholder Returns: Over the past year, the company's stock price has declined significantly, resulting in negative shareholder returns.
Growth Trajectory:
Historical growth: TG Therapeutics has experienced substantial revenue growth since the launch of Ukoniq. However, the company is still in the early stages of commercialization and faces challenges in scaling up market penetration.
Future growth projections: Analysts expect continued revenue growth for TG Therapeutics in the coming years, driven by increasing Ukoniq prescriptions and potential approvals of ublituximab for MS and NMOSD. Future growth is also contingent upon the success of ongoing clinical trials and the company's ability to expand its product portfolio.
Market Dynamics:
Industry overview: The B-cell malignancies and autoimmune diseases market is characterized by intense competition, rapid technological advancements, and evolving treatment paradigms.
TG Therapeutics' positioning: TG Therapeutics is well-positioned within this competitive landscape, with innovative and differentiated therapies like Ukoniq and ublituximab. However, the company needs to navigate effectively to maintain its market share and achieve profitability.
Competitors:
- Key competitors:
- Gilead Sciences (NASDAQ: GILD): Zydelig (idelalisib)
- Verastem Oncology (NASDAQ: VSTM): Copiktra (duvelisib)
- Roche Holding AG (OTCMKTS: RHHBY): Rituxan (rituximab)
- Biogen Inc. (NASDAQ: BIIB): Tysabri (natalizumab)
- Novartis AG (NYSE: NVS): Gilenya (fingolimod)
- Market share comparison: Gilead's Zydelig holds the leading market share in the US MZL market, followed by Verastem's Copiktra.
- Competitive advantages:
- Ukoniq's unique mechanism of action and efficacy in relapsed/refractory MZL and FL.
- Ublituximab's potential for best-in-class efficacy and safety profile in MS and NMOSD.
- Competitive disadvantages:
- Limited market experience compared to established competitors.
- Dependence on a single marketed product, Ukoniq.
Potential Challenges and Opportunities:
Key Challenges:
- Intense competition from established players.
- Regulatory uncertainties and delays in drug approvals.
- Managing operating expenses.
- Expanding market reach and increasing market share.
Potential Opportunities:
- Successful launch and commercialization of ublituximab.
- Expanding Ukoniq's label to include additional indications.
- Strategic collaborations and partnerships.
- Leveraging artificial intelligence and big data for drug development and market analysis.
Recent Acquisitions (last 3 years):
TGTX did not acquire any companies in the last 3 years.
AI-Based Fundamental Rating:
Based on publicly available data, an AI-based algorithm assigns TG Therapeutics a fundamental rating of 6.5 out of 10. This rating considers various factors, including financial performance, market position, growth potential, and competitive landscape. The rating indicates a moderate long-term investment potential, subject to the company's ability to overcome its challenges and capitalize on its opportunities.
Sources:
- TG Therapeutics Inc. investor relations website: https://ir.tgtx.com/
- SEC filings: https://www.sec.gov/edgar/search/
- Yahoo Finance: https://finance.yahoo.com/quote/TGTX/
- Market research reports: statista.com, grandviewresearch.com
Disclaimer: This analysis is for informational purposes only and should not be considered financial advice. Please conduct your own due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About TG Therapeutics Inc
Exchange | NASDAQ | Headquaters | Morrisville, NC, United States |
IPO Launch date | 1995-12-14 | Chairman, CEO & President | Mr. Michael S. Weiss Esq. |
Sector | Healthcare | Website | https://www.tgtherapeutics.com |
Industry | Biotechnology | Full time employees | 300 |
Headquaters | Morrisville, NC, United States | ||
Chairman, CEO & President | Mr. Michael S. Weiss Esq. | ||
Website | https://www.tgtherapeutics.com | ||
Website | https://www.tgtherapeutics.com | ||
Full time employees | 300 |
TG Therapeutics, Inc., a commercial stage biopharmaceutical company, focuses on the acquisition, development, and commercialization of novel treatments for B-cell mediated diseases in the United States and internationally. It provides BRIUMVI, an anti-CD20 monoclonal antibody for the treatment of adult patients with relapsing forms of multiple sclerosis (RMS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. The company's development pipeline comprises Umbralisib, an oral inhibitor of PI3K-delta inhibitor for the treatment of adult patients with relapsed or refractory marginal zone lymphoma and follicular lymphoma; TG-1701 is an orally available and covalently bound Bruton's tyrosine kinase (BTK) inhibitor that exhibits selectivity to BTK in vitro kinase screening; and TG-1801, a bispecific CD47 and CD19 antibody. Its research pipeline includes various investigational medicines. The company has license agreements with LFB Biotechnologies S.A.S; GTC Biotherapeutics; LFB/GTC LLC; Ildong Pharmaceutical Co. Ltd.; Rhizen Pharmaceuticals, S A. for the development and commercialization of umbralisib; Jiangsu Hengrui Medicine Co.; and Novimmune SA, as well as collaboration agreement with Checkpoint Therapeutics, Inc. for the development and commercialization of anti-PD-L1 and anti-GITR antibody research programs in the field of hematological malignancies. TG Therapeutics, Inc. was incorporated in 1993 and is based in Morrisville, North Carolina.
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