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Voyager Therapeutics Inc (VYGR)VYGR
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Upturn Advisory Summary
11/07/2024: VYGR (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: 40.94% | Upturn Advisory Performance 3 | Avg. Invested days: 32 |
Profits based on simulation | Stock Returns Performance 3 | Last Close 11/07/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: 40.94% | Avg. Invested days: 32 |
Upturn Star Rating | Stock Returns Performance 3 |
Profits based on simulation Last Close 11/07/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 387.19M USD |
Price to earnings Ratio 26.3 | 1Y Target Price 17.33 |
Dividends yield (FY) - | Basic EPS (TTM) 0.27 |
Volume (30-day avg) 655455 | Beta 0.89 |
52 Weeks Range 5.71 - 11.72 | Updated Date 11/8/2024 |
Company Size Small-Cap Stock | Market Capitalization 387.19M USD | Price to earnings Ratio 26.3 | 1Y Target Price 17.33 |
Dividends yield (FY) - | Basic EPS (TTM) 0.27 | Volume (30-day avg) 655455 | Beta 0.89 |
52 Weeks Range 5.71 - 11.72 | Updated Date 11/8/2024 |
Earnings Date
Report Date 2024-11-04 | When AfterMarket |
Estimate -0.45 | Actual - |
Report Date 2024-11-04 | When AfterMarket | Estimate -0.45 | Actual - |
Profitability
Profit Margin 6.28% | Operating Margin (TTM) -50.8% |
Management Effectiveness
Return on Assets (TTM) -1.11% | Return on Equity (TTM) 3.38% |
Revenue by Products
Valuation
Trailing PE 26.3 | Forward PE - |
Enterprise Value 63106103 | Price to Sales(TTM) 2.69 |
Enterprise Value to Revenue 0.44 | Enterprise Value to EBITDA 2.59 |
Shares Outstanding 54533300 | Shares Floating 36236257 |
Percent Insiders 17.01 | Percent Institutions 68.91 |
Trailing PE 26.3 | Forward PE - | Enterprise Value 63106103 | Price to Sales(TTM) 2.69 |
Enterprise Value to Revenue 0.44 | Enterprise Value to EBITDA 2.59 | Shares Outstanding 54533300 | Shares Floating 36236257 |
Percent Insiders 17.01 | Percent Institutions 68.91 |
Analyst Ratings
Rating 4.7 | Target Price 13.67 | Buy 1 |
Strong Buy 8 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.7 | Target Price 13.67 | Buy 1 | Strong Buy 8 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Voyager Therapeutics Inc.: A Comprehensive Overview
Company Profile
Detailed History and Background:
Voyager Therapeutics Inc. (VYGR) is a clinical-stage gene therapy company founded in 2014 and headquartered in Cambridge, Massachusetts. It focuses on developing treatments for neurological disorders, primarily targeting severe diseases with high unmet medical needs. Voyager leverages its proprietary AAV gene therapy platform to deliver therapeutic genes directly to the central nervous system.
Core Business Areas:
- Gene Therapy Development: Voyager's core business involves developing and commercializing gene therapies for neurological disorders. The company's pipeline includes therapies for Huntington's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and Friedreich's ataxia.
- Gene Therapy Platform: Voyager has developed a proprietary adeno-associated virus (AAV) vector platform for delivering therapeutic genes to the central nervous system. This platform enables targeted delivery and sustained expression of the therapeutic gene.
Leadership Team and Corporate Structure:
- **总裁兼首席执行官:**D. Lansing Taylor
- **首席科學官:**Diana J. Brain, 醫學博士
- **首席財務官:**兼務會計官,Elizabeth A. Croom
The company's Board of Directors includes experienced professionals from the biotech and pharmaceutical industries.
Top Products and Market Share
Top Products and Offerings:
Voyager does not currently have any marketed products. Its lead product candidates include:
- VY-HTT01: A gene therapy for Huntington's disease
- VY-AADC: A gene therapy for Parkinson's disease
- VY-SOD1: A gene therapy for ALS
- VY-FXT01: A gene therapy for Friedreich's ataxia
Market Share Analysis:
As Voyager does not have any marketed products, it does not have a market share in the global or US markets. However, its product candidates target markets with significant unmet medical needs and potential for growth.
Product Performance and Market Reception:
Voyager's product candidates are still in clinical development stages. Early-stage clinical data for VY-HTT01 and VY-AADC have shown promising results in terms of safety and efficacy. However, long-term safety and efficacy data are still needed before these therapies can be approved for commercialization.
Total Addressable Market
The total addressable market for Voyager's gene therapy products is estimated to be significant. For example, the global market for Huntington's disease treatments was valued at approximately $1.3 billion in 2022 and is expected to grow to $2.2 billion by 2028. Similarly, the global market for Parkinson's disease treatments was valued at approximately $13.4 billion in 2022 and is expected to grow to $22.4 billion by 2028.
Financial Performance
Recent Financial Statements Analysis:
Voyager is a clinical-stage company with no marketed products. As a result, it does not generate any revenue. The company's financial performance is primarily driven by research and development expenses, administrative expenses, and non-operating income.
Year-over-Year Financial Performance Comparison:
Voyager's R&D expenses have increased significantly in recent years as the company advances its clinical development programs. In 2022, R&D expenses were $134.3 million, compared to $91.4 million in 2021. The company's net loss has also increased, from $116.2 million in 2021 to $153.2 million in 2022.
Cash Flow and Balance Sheet Health:
As of December 31, 2022, Voyager had cash and cash equivalents of $247.2 million. The company's balance sheet appears to be healthy, with sufficient cash to fund its ongoing operations and clinical development programs.
Dividends and Shareholder Returns
Dividend History:
Voyager does not currently pay dividends.
Shareholder Returns:
Voyager's stock price has been volatile in recent years. The company's stock price has a 5-year total return of approximately -65%.
Growth Trajectory
Historical Growth Analysis:
Voyager has experienced significant growth in recent years as the company advances its clinical development programs. The company's R&D expenses have increased substantially, and its clinical pipeline has expanded.
Future Growth Projections:
Voyager's future growth potential is tied to the success of its clinical development programs. If the company's lead product candidates are approved for commercialization, it could generate significant revenue and盈利. However, the path to commercialization is uncertain, and there is no guarantee that Voyager's therapies will be successful.
Recent Product Launches and Strategic Initiatives:
Voyager has recently initiated several strategic initiatives to advance its clinical development programs. The company has also entered into partnerships with other companies to develop and commercialize its gene therapies.
Market Dynamics
Industry Overview:
The gene therapy industry is a rapidly growing market with significant potential. The global gene therapy market was valued at approximately $2.4 billion in 2022 and is expected to grow to $12.6 billion by 2028.
Voyager's Positioning and Adaptability:
Voyager is well-positioned within the gene therapy industry with its proprietary AAV platform and promising product candidates. The company is adaptable to market changes and has demonstrated a willingness to pursue strategic partnerships and collaborations.
Competitors
Key Competitors:
- AveXis (AVXS)
- BioMarin Pharmaceutical Inc. (BMRN)
- uniQure N.V. (QURE)
- Spark Therapeutics (ONCE)
Market Share and Comparison:
Voyager does not currently have any marketed products, so it does not have a market share in the gene therapy market. However, its competitors have approved gene therapies on the market. AveXis has Zolgensma, a gene therapy for spinal muscular atrophy, which generated $1.8 billion in revenue in 2022. BioMarin has Roctavian, a gene therapy for hemophilia A, which generated $448 million in revenue in 2022.
Competitive Advantages and Disadvantages:
Voyager's competitive advantages include its proprietary AAV platform, its promising product candidates, and its experienced management team. However, the company faces competition from larger and more established pharmaceutical companies with more resources and experience in developing and commercializing gene therapies.
Potential Challenges and Opportunities
Key Challenges:
- Clinical Development Risks: The success of Voyager's clinical development programs is uncertain, and there is a risk that its therapies may not be approved for commercialization.
- Competition: Voyager faces competition from larger and more established pharmaceutical companies developing gene therapies.
- Manufacturing and Supply Chain Challenges: Gene therapy development and manufacturing are complex and can be challenging to scale up.
Potential Opportunities:
- Market Growth: The gene therapy market is expected to grow significantly in the coming years, providing Voyager with a large potential market for its products.
- Strategic Partnerships: Voyager can leverage strategic partnerships to develop and commercialize its gene therapies.
- New Product Innovations: Voyager continues to explore new gene therapy targets and technologies, which could lead to future growth opportunities.
Recent Acquisitions
Voyager has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating
Based on an AI-based analysis of Voyager's fundamentals, the company receives a rating of 6 out of 10.
Justification:
- Financial Health: Voyager has a limited cash runway and no revenue, which raises concerns about its financial health.
- Market Position: Voyager is in a rapidly growing market with significant potential, but it faces competition from larger and more established companies.
- Future Prospects: Voyager's future prospects are tied to the success of its clinical development programs. If the company's therapies are approved for commercialization, it could generate significant revenue and earnings. However, the path to commercialization is uncertain.
Sources and Disclaimers
Sources:
- Voyager Therapeutics Inc. Investor Relations website
- Bloomberg Terminal
- Securities and Exchange Commission (SEC) filings
Disclaimer:
The information provided in this analysis should not be considered financial advice. It is essential to conduct your research and consult with a qualified financial professional before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Voyager Therapeutics Inc
Exchange | NASDAQ | Headquaters | Lexington, MA, United States |
IPO Launch date | 2015-11-11 | President, CEO & Director | Dr. Alfred W. Sandrock Jr., M.D., Ph.D. |
Sector | Healthcare | Website | https://www.voyagertherapeutics.com |
Industry | Biotechnology | Full time employees | 162 |
Headquaters | Lexington, MA, United States | ||
President, CEO & Director | Dr. Alfred W. Sandrock Jr., M.D., Ph.D. | ||
Website | https://www.voyagertherapeutics.com | ||
Website | https://www.voyagertherapeutics.com | ||
Full time employees | 162 |
Voyager Therapeutics, Inc., a biotechnology company, focuses on the treatment of gene therapy and neurology diseases. The company's lead clinical candidate is VY-TAU01, an anti-tau antibody program for the treatment of alzheimer's disease. Its product pipeline includes superoxide dismutase 1 silencing gene therapy, which is in preclinical trial for the treatment of amyotrophic lateral sclerosis; tau silencing gene therapy, which is in preclinical trial for the treatment of alzheimer's disease; and vectorized anti-amyloid antibody, a gene therapy targeting anti-amyloid for the treatment of alzheimer's disease and is in preclinical trial. In addition, the company develops VY-FXN01, which is in preclinical trial to treat friedreich's ataxia; and GBA1 gene replacement to treat parkinson's disease and is in preclinical trial. Further, it provides research program for the treatment of Huntington's disease. The company has collaboration and license agreements with Alexion; AstraZeneca Rare Disease; Novartis Pharma AG; Neurocrine Biosciences, Inc; and Sangamo Therapeutics, Inc. Voyager Therapeutics, Inc. was incorporated in 2013 and is headquartered in Lexington, Massachusetts.
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