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PRME
Upturn stock ratingUpturn stock rating

Prime Medicine, Inc. Common Stock (PRME)

Upturn stock ratingUpturn stock rating
$1.3
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

04/07/2025: PRME (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

ratingratingratingratingrating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

ratingratingratingratingrating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -73.14%
Avg. Invested days 22
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/07/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 184.94M USD
Price to earnings Ratio -
1Y Target Price 13.1
Price to earnings Ratio -
1Y Target Price 13.1
Volume (30-day avg) 1498766
Beta 1.89
52 Weeks Range 1.26 - 8.27
Updated Date 04/6/2025
52 Weeks Range 1.26 - 8.27
Updated Date 04/6/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.65

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -2025.74%

Management Effectiveness

Return on Assets (TTM) -51.51%
Return on Equity (TTM) -136.88%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 35288787
Price to Sales(TTM) 62
Enterprise Value 35288787
Price to Sales(TTM) 62
Enterprise Value to Revenue 11.83
Enterprise Value to EBITDA -3.1
Shares Outstanding 131161000
Shares Floating 60638823
Shares Outstanding 131161000
Shares Floating 60638823
Percent Insiders 23.91
Percent Institutions 59.07

Analyst Ratings

Rating 4.5
Target Price 13.7
Buy 4
Strong Buy 7
Buy 4
Strong Buy 7
Hold 1
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Prime Medicine, Inc. Common Stock

stock logo

Company Overview

overview logo History and Background

Prime Medicine, Inc. was founded in 2020, focusing on developing prime editing, a versatile gene editing technology. It went public in 2022. The company is still in the early stages of development and pre-revenue.

business area logo Core Business Areas

  • Gene Editing Therapeutics: Prime Medicine is dedicated to creating potentially curative gene editing therapies using its prime editing technology across a range of diseases.

leadership logo Leadership and Structure

Keith Gottesdiener is the CEO. The company has a management team focused on research, development, and business operations. The organizational structure supports its research-driven focus.

Top Products and Market Share

overview logo Key Offerings

  • Prime Editing Technology: Prime editing is Prime Medicine's core technology, aimed at precisely correcting genetic defects. It is currently in pre-clinical development. Competitors include companies using CRISPR-Cas9 and other gene editing technologies such as Beam Therapeutics (BEAM) and Editas Medicine (EDIT).

Market Dynamics

industry overview logo Industry Overview

The gene editing industry is rapidly evolving, with significant potential for treating genetic diseases. However, it also faces regulatory hurdles and challenges related to safety and efficacy.

Positioning

Prime Medicine is positioned as a leader in prime editing technology. Its competitive advantage lies in the precision and versatility of its prime editing approach, which addresses limitations of previous gene editing methods.

Total Addressable Market (TAM)

The TAM for gene editing therapies is estimated to be in the tens of billions of dollars. Prime Medicine is positioned to capture a significant portion of this market if its technology proves successful and scalable.

Upturn SWOT Analysis

Strengths

  • Novel prime editing technology
  • Strong intellectual property position
  • Experienced leadership team
  • Potential for precise and versatile gene editing

Weaknesses

  • Early stage of development
  • High cash burn rate
  • Dependence on a single technology
  • Unproven clinical efficacy

Opportunities

  • Partnerships with pharmaceutical companies
  • Expansion of pipeline into new disease areas
  • Advancements in delivery technologies
  • Regulatory approvals for prime editing therapies

Threats

  • Competition from other gene editing technologies
  • Regulatory setbacks
  • Clinical trial failures
  • Ethical concerns surrounding gene editing

Competitors and Market Share

competitor logo Key Competitors

  • CRSP
  • EDIT
  • BEAM
  • NTLA

Competitive Landscape

Prime Medicine's prime editing technology distinguishes it, but it faces intense competition from established gene editing companies. Success depends on demonstrating superior efficacy and safety.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by the progression of its pre-clinical programs and expansion of its intellectual property portfolio.

Future Projections: Future growth is contingent on successful clinical trials and regulatory approvals. Analyst estimates vary depending on the perceived potential of prime editing.

Recent Initiatives: Recent initiatives include advancing lead programs towards clinical trials and securing partnerships to expand its platform.

Summary

Prime Medicine is a high-risk, high-reward biotech company focused on prime editing. Its strength lies in its novel technology and experienced team. However, it faces significant challenges in clinical development, competition, and regulatory hurdles. Success depends on demonstrating the efficacy and safety of its prime editing technology.

Similar Companies

BEAMratingrating

Beam Therapeutics Inc

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BEAMratingrating

Beam Therapeutics Inc

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CRSPratingrating

Crispr Therapeutics AG

$32.38
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CRSPratingrating

Crispr Therapeutics AG

$32.38
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EDITratingrating

Editas Medicine Inc

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EDITratingrating

Editas Medicine Inc

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NTLAratingrating

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Intellia Therapeutics Inc

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VRTXratingrating

Vertex Pharmaceuticals Inc

$474.56
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Consider higher Upturn Star rating
BUY since 45 days

VRTXratingrating

Vertex Pharmaceuticals Inc

$474.56
Large-Cap Stock
BUY since 45 days
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Consider higher Upturn Star rating

Sources and Disclaimers

Data Sources:

  • Company filings (SEC)
  • Analyst reports
  • Industry publications
  • Company Website

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. The biotechnology industry is inherently risky, and results are subject to change.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Prime Medicine, Inc. Common Stock

Exchange NASDAQ
Headquaters Cambridge, MA, United States
IPO Launch date 2022-10-20
President, CEO, Secretary & Director Dr. Keith Michael Gottesdiener M.D., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 214
Full time employees 214

Prime Medicine, Inc., a biotechnology company, engages in delivering genetic therapies to address the spectrum of diseases by deploying gene editing technology in the United States. It offers Prime Editing technology comprising a programmable DNA binding domains, such as Cas domains, are typically modified such that they do not cause a double-stranded break in the DNA, as well as a RT domain that copies the edited DNA sequence directly into the target genomic site where the edit is made; and pegRNA which contains a search sequence, also known as a spacer, which provides a target genomic address for the Prime Editor. The company has a research collaboration with Cimeio Therapeutics to develop Prime Edited Shielded-Cell & Immunotherapy Pairs for genetic diseases, acute myeloid leukemia, and myelodysplastic syndrome. Prime Medicine, Inc. was incorporated in 2019 and is headquartered in Cambridge, Massachusetts.

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