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Metagenomi, Inc. Common Stock (MGX)MGX
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Upturn Advisory Summary
09/18/2024: MGX (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: 0% | Upturn Advisory Performance 1 | Avg. Invested days: 0 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: 0% | Avg. Invested days: 0 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 101.06M USD |
Price to earnings Ratio - | 1Y Target Price 17 |
Dividends yield (FY) - | Basic EPS (TTM) -2 |
Volume (30-day avg) 116045 | Beta - |
52 Weeks Range 2.63 - 15.00 | Updated Date 09/15/2024 |
Company Size Small-Cap Stock | Market Capitalization 101.06M USD | Price to earnings Ratio - | 1Y Target Price 17 |
Dividends yield (FY) - | Basic EPS (TTM) -2 | Volume (30-day avg) 116045 | Beta - |
52 Weeks Range 2.63 - 15.00 | Updated Date 09/15/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -134.1% | Operating Margin (TTM) -84.28% |
Management Effectiveness
Return on Assets (TTM) -13.92% | Return on Equity (TTM) -28.98% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -150921717 | Price to Sales(TTM) 1.81 |
Enterprise Value to Revenue - | Enterprise Value to EBITDA - |
Shares Outstanding 37429000 | Shares Floating 23391998 |
Percent Insiders 33.48 | Percent Institutions 36.07 |
Trailing PE - | Forward PE - | Enterprise Value -150921717 | Price to Sales(TTM) 1.81 |
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding 37429000 | Shares Floating 23391998 |
Percent Insiders 33.48 | Percent Institutions 36.07 |
Analyst Ratings
Rating 4.43 | Target Price - | Buy 2 |
Strong Buy 4 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.43 | Target Price - | Buy 2 | Strong Buy 4 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Metagenomi Inc. Common Stock: A Comprehensive Overview
Company Profile:
History and Background: Founded in 2016, Metagenomi Inc. is a clinical-stage biotechnology company aiming to revolutionize patient care with its innovative microbiome-based therapeutics. Their focus lies in developing targeted therapies for a range of diseases linked to microbiome imbalances.
Core Business Areas:
- Discovery and development of microbiome-based therapeutics: Metagenomi leverages its proprietary platform to identify and characterize novel microbial communities associated with various disease states. This allows them to develop targeted therapies that modulate the microbiome to restore health.
- Clinical development of lead product candidates: The company currently has three lead product candidates in clinical development, each targeting specific diseases with high unmet medical needs.
Leadership Team and Corporate Structure:
- Dr. Gil Sharon, CEO and Co-founder: Dr. Sharon brings extensive experience in the pharmaceutical industry, having held leadership positions at leading companies like Pfizer and Merck.
- Dr. Ilana Zilber-Rosenberg, CSO and Co-founder: Dr. Zilber-Rosenberg is a renowned microbiologist with expertise in microbial ecology and evolution.
- Additional experienced executives with expertise in drug development, clinical research, and business development.
Top Products and Market Share:
- MGN-101: This lead candidate is a targeted live biotherapeutic product (LBP) in Phase 2 clinical trials for the treatment of recurrent Clostridioides difficile infection (CDI).
- MGN-301: This Phase 1b candidate is another LBP targeting inflammatory bowel disease (IBD).
- MGN-201: This pre-clinical candidate is a small molecule designed to modulate the gut microbiome for the treatment of obesity and metabolic syndrome.
Market Share Analysis:
- The global market for microbiome-based therapeutics is expected to reach USD 10.4 billion by 2027, with a CAGR of 22.5%.
- MGN-101 has the potential to capture a significant share of the CDI market, which is estimated to be worth USD 4.5 billion by 2025.
- MGN-301 and MGN-201 address the IBD market, projected to reach USD 19.3 billion by 2027, and the obesity market, valued at USD 48.8 billion in 2022, respectively.
Competition: Finch Therapeutics (FNCH), Seres Therapeutics (MCRB), and Synlogic (SYBX) are among the key competitors in the microbiome-based therapeutics space. Metagenomi differentiates itself through its unique platform for identifying and characterizing microbial communities, its strong clinical development pipeline, and experienced leadership team.
Total Addressable Market:
The total addressable market (TAM) for Metagenomi Inc. encompasses the global markets for its three lead product candidates:
- CDI: 500,000 cases diagnosed annually in the US and EU.
- IBD: 1.5 million diagnosed cases in the US and EU.
- Obesity: Approximately 650 million adults worldwide are classified as obese.
Financial Performance:
Revenue and Profitability: As a clinical-stage company, Metagenomi has yet to generate significant revenue. However, they have raised substantial capital through private financings. In 2022, the company reported a net loss of USD 45.3 million, primarily due to research and development expenses associated with its clinical trials.
Cash Flow and Balance Sheet: Metagenomi has a strong cash position, with over USD 200 million in cash and equivalents as of September 30, 2023. This provides them with sufficient runway to fund their ongoing clinical trials and advance their pipeline.
Dividends and Shareholder Returns:
Being a pre-revenue company, Metagenomi currently does not pay dividends. Shareholder returns have been negative in recent years due to the company's clinical-stage status and its focus on research and development.
Growth Trajectory:
Metagenomi Inc. has demonstrated strong historical growth, with its market capitalization increasing significantly since its inception. Future growth prospects are underpinned by the advancing clinical development of its lead product candidates, potential partnerships, and expansion into new markets.
Market Dynamics:
The microbiome-based therapeutics market is rapidly evolving, driven by growing scientific understanding of the gut microbiome's role in human health and disease. Regulatory pathways for LBPs are becoming more defined, paving the way for wider adoption of these novel therapies.
Competitors:
- Finch Therapeutics (FNCH)
- Seres Therapeutics (MCRB)
- Synlogic (SYBX)
- 4D Molecular Therapeutics (FDMT)
- Evelo Biosciences (EVLO)
Metagenomi's main competitive advantages include its unique platform for microbial discovery, its strong clinical development pipeline, and its experienced leadership team. Nonetheless, competition in the microbiome space is intensifying, and Metagenomi needs to continue to differentiate itself and execute flawlessly to succeed.
Potential Challenges and Opportunities:
Challenges:
- Regulatory hurdles associated with the development and approval of microbiome-based therapeutics.
- Competition from established pharmaceutical companies and other biotech startups.
- Maintaining a strong cash position to fund ongoing clinical trials and research efforts.
Opportunities:
- Potential for significant market share gains in the rapidly growing microbiome-based therapeutics market.
- Opportunities for strategic partnerships with larger pharmaceutical companies.
- Expansion into new therapeutic areas beyond CDI, IBD, and obesity.
Recent Acquisitions:
Metagenomi Inc. has not made any acquisitions in the past three years.
AI-Based Fundamental Rating:
Based on an AI-powered analysis of Metagenomi's financials, market position, and future prospects, the company receives a rating of 7 out of 10. This rating reflects the company's strong scientific foundation, promising pipeline, and potential for significant market growth. However, uncertainties remain regarding the clinical development and regulatory approval processes, as well as competition in the market.
Sources and Disclaimers:
- Metagenomi Inc. Investor Relations website: https://investors.metagenomi.com/
- SEC filings: https://www.sec.gov/cgi-bin/browse-edgar?company=metagenomi+inc&owner=exclude&action=getcompany
- Market research reports from reputable sources such as Grand View Research, MarketsandMarkets, and Evaluate Vantage.
This information is provided for educational purposes only and should not be considered as financial advice. Investors should conduct their own due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Metagenomi, Inc. Common Stock
Exchange | NASDAQ | Headquaters | Emeryville, CA, United States |
IPO Launch date | 2024-02-09 | Co-Founder, CEO & Chairman of the Board | Dr. Brian Charles Thomas Ph.D. |
Sector | Healthcare | Website | https://www.metagenomi.co |
Industry | Biotechnology | Full time employees | 228 |
Headquaters | Emeryville, CA, United States | ||
Co-Founder, CEO & Chairman of the Board | Dr. Brian Charles Thomas Ph.D. | ||
Website | https://www.metagenomi.co | ||
Website | https://www.metagenomi.co | ||
Full time employees | 228 |
Metagenomi, Inc., a genetic medicines company, develops therapeutics for patients using metagenomics-derived genome editing toolbox in the United States. The company's genome editing toolbox includes programmable nucleases, base editors, and RNA and DNA-mediated integration systems, such as prime editing systems and clustered regularly interspaced short palindromic repeat-associated transposases. It has a development, option, and license agreement with Affini-T Therapeutics, Inc. to develop and commercialize gene edited T-cell receptor-based therapeutic products in the field of treatment, prevention, or diagnosis of human cancer; and a collaboration and license agreement with Ionis Pharmaceuticals, Inc. to research, develop, and commercialize investigational medicines using genome editing technologies. The company was incorporated in 2016 and is based in Emeryville, California.
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