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Kura Oncology Inc (KURA)KURA
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Upturn Advisory Summary
09/18/2024: KURA (2-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -4.9% | Upturn Advisory Performance 1 | Avg. Invested days: 28 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -4.9% | Avg. Invested days: 28 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.54B USD |
Price to earnings Ratio - | 1Y Target Price 30.42 |
Dividends yield (FY) - | Basic EPS (TTM) -2.23 |
Volume (30-day avg) 507786 | Beta 0.84 |
52 Weeks Range 7.41 - 24.17 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 1.54B USD | Price to earnings Ratio - | 1Y Target Price 30.42 |
Dividends yield (FY) - | Basic EPS (TTM) -2.23 | Volume (30-day avg) 507786 | Beta 0.84 |
52 Weeks Range 7.41 - 24.17 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -24.77% | Return on Equity (TTM) -39.27% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 1070165439 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.48 |
Shares Outstanding 76634496 | Shares Floating 49085927 |
Percent Insiders 1.07 | Percent Institutions 107.33 |
Trailing PE - | Forward PE - | Enterprise Value 1070165439 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.48 | Shares Outstanding 76634496 | Shares Floating 49085927 |
Percent Insiders 1.07 | Percent Institutions 107.33 |
Analyst Ratings
Rating 4.64 | Target Price 29.88 | Buy 3 |
Strong Buy 10 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.64 | Target Price 29.88 | Buy 3 | Strong Buy 10 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Comprehensive Overview of Kura Oncology Inc.
Company Profile
Detailed history and background:
Kura Oncology is a clinical-stage biopharmaceutical company focused on the development and commercialization of therapies for oncology indications with unmet medical need. Founded in 2006 as a spin-off from DuPont, the company initially focused on the development of vaccines for infectious diseases. However, in 2013, Kura shifted its focus to oncology, and in 2016, it completed its initial public offering (IPO).
Core business areas:
Kura Oncology's core business areas are:
- Development of novel therapies for oncology indications: The company primarily focuses on developing therapies that target the tumor microenvironment (TME) and modulate the immune system to fight cancer.
- Utilizing its differentiated drug platform: Kura leverages its expertise in macrocycles and protein engineering to develop new therapies with improved efficacy and safety profiles.
Leadership team and corporate structure:
The leadership team at Kura Oncology includes:
- Troy Wilson, Ph.D.: President and Chief Executive Officer
- Nima Sharifi, M.D.: Chief Medical Officer
- Elizabeth A. O'Day, Ph.D.: Chief Development Officer
- James D. Ezell, Ph.D.: Chief Scientific Officer
- Michael G. Sgamboti, Jr.: Chief Financial Officer
The company operates with a Board of Directors and executive leadership team responsible for driving its strategic direction and overall operations.
Top Products and Market Share
Top products and offerings:
Kura Oncology's current pipeline includes three clinical-stage drug candidates:
- Tipifarnib: A first-in-class, orally bioavailable, farnesyltransferase inhibitor (FTI) currently in Phase 2 development for the treatment of advanced solid tumors.
- KRT-232: A second-generation FTI in Phase 1 development for advanced solid tumors, specifically targeting Kirsten rat sarcoma viral oncogene homolog (KRAS) mutant tumors.
- KO-539: A first-in-class, macrocyclic small molecule designed to selectively target and degrade Bruton's tyrosine kinase (BTK) for the treatment of B-cell malignancies. It is currently in Phase 1 development.
Market share and competitor comparison:
Kura Oncology's products are currently in development and have not yet received regulatory approval. Therefore, they do not have a market share in the global or US markets. However, once approved, they will compete with existing therapies for their respective indications.
Total Addressable Market
Market size:
The global oncology market is estimated to be worth over $150 billion and is expected to continue growing due to the increasing prevalence of cancer and advancements in treatment options. The specific markets for Kura's drug candidates are:
- Tipifarnib: The market for advanced solid tumors is estimated to be over $50 billion.
- KRT-232: The market for KRAS mutant tumors is estimated to be over $10 billion.
- KO-539: The market for B-cell malignancies is estimated to be over $20 billion.
Financial Performance
Financial statements analysis:
Kura is a clinical-stage company and does not currently generate significant revenue. As of June 30, 2023, the company had a net loss of $43.8 million and a cash and cash equivalents balance of $160.6 million.
Year-over-year comparison:
Kura's net losses have been increasing in recent years as the company invests in clinical development activities.
Cash flow and balance sheet:
Kura has a strong cash position and is well-funded to support its ongoing clinical trials.
Dividends and Shareholder Returns
Dividend history:
Kura Oncology has never paid dividends and does not currently intend to do so.
Shareholder returns:
Kura's stock price has been volatile in recent years, reflecting the risks associated with its clinical-stage development programs.
Growth Trajectory
Historical growth analysis:
Kura has experienced significant growth in its research and development activities in recent years.
Future growth projections:
The company's future growth will depend on the success of its clinical trials and the commercialization of its drug candidates.
Recent strategic initiatives:
Kura has recently partnered with other companies to develop and commercialize its drug candidates.
Market Dynamics
Industry trends:
The oncology market is characterized by rapid innovation and increasing competition.
Demand-supply scenarios:
The demand for new and effective cancer treatments is high, and the supply of these treatments is constantly evolving.
Technological advancements:
Advances in areas such as immunotherapy and targeted therapies are driving the development of new cancer treatments.
Kura's positioning and adaptability:
Kura is well-positioned in the oncology market due to its focus on novel therapies and its differentiated drug platform. The company is also adaptable to market changes through its strategic partnerships and development of new drug candidates.
Competitors
Key competitors:
- Amgen (AMGN)
- Bristol-Myers Squibb (BMY)
- Pfizer (PFE)
- Merck (MRK)
- Roche (RHHBY)
Market share and competitive advantages:
Kura's competitors have a larger market share and more established product portfolios. However, Kura has several competitive advantages, including its novel therapeutic approach, its differentiated drug platform, and its strong cash position.
Potential Challenges and Opportunities
Key challenges:
- Kura faces the challenge of developing and commercializing its drug candidates successfully.
- The company also faces competition from larger and more established pharmaceutical companies.
- Clinical trial results and regulatory approvals are key risks for Kura's future.
Potential opportunities:
- Kura has the opportunity to develop first-in-class therapies for cancer patients with unmet medical needs.
- The company can also leverage its expertise and partnerships to expand its product portfolio and market reach.
Recent Acquisitions
Kura has not made any acquisitions in the last three years.
AI-Based Fundamental Rating
Based on an AI-based rating system, Kura Oncology receives a rating of 6 out of 10. This rating is based on the company's strong cash position, its differentiated drug platform, and its potential for growth. However, the company also faces significant risks associated with its clinical-stage development programs and competition from larger pharmaceutical companies.
Sources and Disclaimers
Sources:
- Kura Oncology website
- SEC filings
- Market research reports
Disclaimer:
This information is provided for educational purposes only and should not be considered investment advice. Investors should conduct their independent research and due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Kura Oncology Inc
Exchange | NASDAQ | Headquaters | San Diego, CA, United States |
IPO Launch date | 2015-09-22 | Chairman, CEO & President | Dr. Troy Edward Wilson J.D., Ph.D. |
Sector | Healthcare | Website | https://kuraoncology.com |
Industry | Biotechnology | Full time employees | 142 |
Headquaters | San Diego, CA, United States | ||
Chairman, CEO & President | Dr. Troy Edward Wilson J.D., Ph.D. | ||
Website | https://kuraoncology.com | ||
Website | https://kuraoncology.com | ||
Full time employees | 142 |
Kura Oncology, Inc., a clinical-stage biopharmaceutical company, develops medicines for the treatment of cancer. The company's pipeline consists of small molecule product candidates that target cancer. Its lead product candidates are ziftomenib, an orally bioavailable small molecule inhibitor of the menin-KMT2A interaction for the treatment of genetically defined subsets of acute leukemias, including acute myeloid leukemia and acute lymphoblastic leukemia; tipifarnib, an orally bioavailable farnesyl transferase inhibitor combination with alpelisib for patients with PIK3CA-dependent HNSCC; and KO-2806, a farnesyl transferase inhibitor for the treatment of solid tumors. It has a clinical collaboration with Novartis Pharma AG to evaluate the combination of tipifarnib and alpelisib in patients with head and neck squamous cell carcinoma whose tumors have HRAS overexpression and/or PIK3CA mutation and/or amplification. The company was founded in 2014 and is headquartered in San Diego, California.
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