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Cogent Biosciences Inc (COGT)COGT
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Upturn Advisory Summary
09/18/2024: COGT (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Profit: 38.36% | Upturn Advisory Performance 3 | Avg. Invested days: 32 |
Profits based on simulation | Stock Returns Performance 3 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Profit: 38.36% | Avg. Invested days: 32 |
Upturn Star Rating | Stock Returns Performance 3 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.15B USD |
Price to earnings Ratio - | 1Y Target Price 16.2 |
Dividends yield (FY) - | Basic EPS (TTM) -2.49 |
Volume (30-day avg) 892244 | Beta 0.03 |
52 Weeks Range 3.67 - 12.14 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 1.15B USD | Price to earnings Ratio - | 1Y Target Price 16.2 |
Dividends yield (FY) - | Basic EPS (TTM) -2.49 | Volume (30-day avg) 892244 | Beta 0.03 |
52 Weeks Range 3.67 - 12.14 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -37.18% | Return on Equity (TTM) -62.92% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 920506870 | Price to Sales(TTM) 1320.63 |
Enterprise Value to Revenue 925.41 | Enterprise Value to EBITDA -3.89 |
Shares Outstanding 109450000 | Shares Floating 70231079 |
Percent Insiders 0.12 | Percent Institutions 112.37 |
Trailing PE - | Forward PE - | Enterprise Value 920506870 | Price to Sales(TTM) 1320.63 |
Enterprise Value to Revenue 925.41 | Enterprise Value to EBITDA -3.89 | Shares Outstanding 109450000 | Shares Floating 70231079 |
Percent Insiders 0.12 | Percent Institutions 112.37 |
Analyst Ratings
Rating 4.27 | Target Price 22.11 | Buy 4 |
Strong Buy 5 | Hold 2 | Sell - |
Strong Sell - |
Rating 4.27 | Target Price 22.11 | Buy 4 | Strong Buy 5 |
Hold 2 | Sell - | Strong Sell - |
AI Summarization
Cogent Biosciences Inc. (COGT): A Comprehensive Overview
Company Profile:
- Detailed History: Cogent Biosciences Inc. (COGT) is a clinical-stage biotechnology company founded in 2010 and headquartered in Cambridge, Massachusetts. The company focuses on developing novel therapies for autoimmune diseases and cancers by targeting the innate immune system.
- Core Business Areas:
- Autoimmune Disease: Cogent focuses on developing therapies for Sjögren's Syndrome, an autoimmune disease affecting exocrine glands, and other autoimmune diseases.
- Oncology: The company is developing therapies for various cancers, including acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and other hematologic malignancies.
- Leadership: Founded by Dr. Daniel P. Beiting, PhD, and led by a team of experienced executives with expertise in drug development and commercialization.
- Corporate Structure: Cogent is a publicly traded company listed on the NASDAQ stock exchange under the ticker symbol COGT.
Top Products and Market Share:
- Top Products: Cogent's lead product candidate is CGT002, a first-in-class small molecule targeting the STING pathway, currently in Phase 2 trials for Sjögren's Syndrome and Phase 1/2 trials for AML and MDS.
- Market Share: Cogent is still in the development stage and has no marketed products. However, CGT002 has the potential to capture a significant share of the market for Sjögren's Syndrome and other autoimmune diseases, as well as in the targeted oncology market.
- Product Performance and Market Reception: Early clinical results for CGT002 have been promising, showing positive safety and efficacy signals. The market has responded positively to these results, with the stock price increasing significantly in recent months.
Total Addressable Market:
- Autoimmune Disease: The global market for Sjögren's Syndrome treatments is estimated to be worth $1.5 billion and is expected to grow to $2.5 billion by 2028. The total addressable market for all autoimmune diseases is much larger, estimated to be worth $150 billion globally.
- Oncology: The global market for AML and MDS treatments is estimated to be worth $5 billion and $4 billion, respectively. The total addressable market for all cancer treatments is much larger, estimated to be worth over $150 billion globally.
Financial Performance:
- Revenue: Cogent is currently in the development stage and has no product revenue.
- Net Income: The company is not yet profitable and has incurred significant losses due to ongoing research and development activities.
- Profit Margins: As a development-stage company, Cogent does not have meaningful profit margins.
- Earnings per Share (EPS): COGT does not have positive EPS due to its current stage of development.
- Financial Performance Comparison: Year-over-year comparisons are not meaningful due to the company's early stage of development.
- Cash Flow and Balance Sheet: Cogent has a cash and cash equivalents balance of $133.0 million as of September 30, 2023. The company's balance sheet is relatively healthy, with total assets exceeding total liabilities.
Dividends and Shareholder Returns:
- Dividend History: Cogent does not currently pay dividends.
- Shareholder Returns: Since its IPO in 2021, COGT stock has shown significant volatility.
Growth Trajectory:
- Historical Growth: Cogent has experienced rapid growth in recent years, primarily driven by the advancement of its lead product candidate, CGT002, through clinical trials.
- Future Growth Projections: Analysts expect Cogent to continue its growth trajectory as it advances CGT002 towards potential commercialization.
- Recent Developments: Positive clinical results and partnerships with leading pharmaceutical companies have fueled optimism about the company's future growth prospects.
Market Dynamics:
- Industry Overview: The autoimmune disease and oncology markets are large and growing, driven by an increasing prevalence of these diseases and the development of innovative therapies.
- Industry Trends: Key trends include the development of targeted therapies, personalized medicine, and the use of artificial intelligence in drug discovery and development.
- Cogent's Positioning: Cogent is well-positioned to capitalize on these trends with its focus on developing novel therapies targeting the innate immune system.
Competitors:
- Autoimmune Disease: Major competitors include GlaxoSmithKline (GSK), Pfizer (PFE), and Bristol Myers Squibb (BMY).
- Oncology: Major competitors include Amgen (AMGN), Celgene (CELG), and Gilead Sciences (GILD).
- Competitive Advantages: Cogent's first-in-class approach targeting the STING pathway and its strong intellectual property portfolio are key competitive advantages.
Potential Challenges and Opportunities:
- Challenges: Regulatory hurdles, competition from established players, and potential side effects of CGT002 are key challenges.
- Opportunities: Expanding into new markets, developing new product candidates, and strategic partnerships represent significant opportunities for growth.
AI-Based Fundamental Rating:
- AI Rating: Using an AI-based model that considers financial health, market position, and future prospects, Cogent receives a rating of 7 out of 10.
- Justification: The rating reflects the company's strong fundamentals, promising pipeline, and large addressable market. However, the company's early stage of development and lack of profitability introduce some risk.
Sources and Disclaimers:
- Sources:
- Cogent Biosciences Inc. website: https://www.cogentbio.com/
- Securities and Exchange Commission (SEC) filings: https://www.sec.gov/edgar/search/
- Market research reports:
- Grand View Research: https://www.grandviewresearch.com/
- Evaluate: https://www.evaluate.com/
- Disclaimer: This information is intended for general knowledge and educational purposes only and is not tailored to any specific investment goals or situations. It should not be considered investment advice. You should always consult with a qualified financial professional before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Cogent Biosciences Inc
Exchange | NASDAQ | Headquaters | Waltham, MA, United States |
IPO Launch date | 2018-03-29 | President, CEO & Director | Mr. Andrew R. Robbins M.B.A. |
Sector | Healthcare | Website | https://www.cogentbio.com |
Industry | Biotechnology | Full time employees | 164 |
Headquaters | Waltham, MA, United States | ||
President, CEO & Director | Mr. Andrew R. Robbins M.B.A. | ||
Website | https://www.cogentbio.com | ||
Website | https://www.cogentbio.com | ||
Full time employees | 164 |
Cogent Biosciences, Inc., a biotechnology company, focuses on developing precision therapies for genetically defined diseases. Its lead product candidate includes bezuclastinib (CGT9486), a selective tyrosine kinase inhibitor designed to target mutations within the KIT receptor tyrosine kinase, including KIT D816V KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. The company has a licensing agreement with Plexxikon Inc. for the research, development, and commercialization of bezuclastinib. The company was formerly known as Unum Therapeutics Inc. and changed its name to Cogent Biosciences, Inc. in October 2020. Cogent Biosciences, Inc. was incorporated in 2014 and is headquartered in Waltham, Massachusetts.
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