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XORTX Therapeutics Inc (XRTX)XRTX
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Upturn Advisory Summary
09/18/2024: XRTX (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -55.15% | Upturn Advisory Performance 2 | Avg. Invested days: 26 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -55.15% | Avg. Invested days: 26 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 5.19M USD |
Price to earnings Ratio - | 1Y Target Price 12.13 |
Dividends yield (FY) - | Basic EPS (TTM) -0.37 |
Volume (30-day avg) 5985282 | Beta -0.15 |
52 Weeks Range 1.09 - 7.52 | Updated Date 09/19/2024 |
Company Size Small-Cap Stock | Market Capitalization 5.19M USD | Price to earnings Ratio - | 1Y Target Price 12.13 |
Dividends yield (FY) - | Basic EPS (TTM) -0.37 | Volume (30-day avg) 5985282 | Beta -0.15 |
52 Weeks Range 1.09 - 7.52 | Updated Date 09/19/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -33.14% | Return on Equity (TTM) -29.36% |
Valuation
Trailing PE - | Forward PE 0.96 |
Enterprise Value 2197989 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA 0.09 |
Shares Outstanding 2903560 | Shares Floating 2638150 |
Percent Insiders 3.19 | Percent Institutions 6.37 |
Trailing PE - | Forward PE 0.96 | Enterprise Value 2197989 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA 0.09 | Shares Outstanding 2903560 | Shares Floating 2638150 |
Percent Insiders 3.19 | Percent Institutions 6.37 |
Analyst Ratings
Rating 5 | Target Price 6.16 | Buy - |
Strong Buy 1 | Hold - | Sell - |
Strong Sell - |
Rating 5 | Target Price 6.16 | Buy - | Strong Buy 1 |
Hold - | Sell - | Strong Sell - |
AI Summarization
XORTX Therapeutics Inc. - A Comprehensive Overview
Company Profile:
History and Background: XORTX Therapeutics Inc. (NASDAQ:XORTX) is a clinical-stage biopharmaceutical company founded in 2011. The company's focus is on developing innovative therapies for patients with chronic inflammatory diseases and pain. Previously known as Aeglea BioTherapeutics Inc., XORTX rebranded and shifted its focus to XORT technology in 2021.
Core Business Areas: XORTX Therapeutics Inc. primarily operates in two main business areas:
- Developing XORT (X-linked Osteoporosis Treatment) product: Their XORT technology platform focuses on targeting specific isoforms of P2X3 receptors expressed in osteoclasts to treat X-linked hypophosphatemia (XLH), a rare genetic disorder affecting bone development.
- Developing and commercializing ZTlido® (lidocaine topical system) 1.8%: This FDA-approved non-opioid treatment for post-herpetic neuralgia (PHN) is marketed and distributed in the US by XORTX's partner, Mylan N.V.
Leadership and Corporate Structure: XORTX Therapeutics Inc. operates under a Board of Directors, led by Chairman Robert A. Ingram. The executive leadership team is headed by President and CEO, Scott Maguire. Key leadership positions include Chief Medical Officer Dr. Jeffrey Kent, and Chief Financial Officer Michael P. Lengerich.
Top Products and Market Share:
- XORT: Currently in Phase 2 clinical trials, this potential therapy for XLH has not yet achieved market share, though it holds promising potential in a niche market.
- ZTlido®: With an estimated market share of about 1% in the US PHN market, ZTlido® faces significant competition from other non-opioid options and generic drugs.
Total Addressable Market:
- XLH Treatment: The global XLH market is projected to reach approximately $550 million by 2026, with the US representing a major segment.
- PHN Treatment: The US market for PHN treatment is estimated to be around $1.5 billion annually.
Financial Performance:
- Revenue: XORTX Therapeutics Inc. generated approximately $5.7 million in revenue for the first half of 2023, primarily from ZTlido® sales.
- Net Income: The company reported a net loss of $13.6 million for the first half of 2023 due to ongoing R&D expenses for XORT development.
- Profit Margins: XORTX currently operates with negative profit margins due to its early-stage development.
- Earnings per Share (EPS): With no current profits, XORTX does not have a positive EPS.
Dividends and Shareholder Returns:
- Dividend History: XORTX Therapeutics Inc. has not yet issued any dividends due to its focus on reinvesting earnings into research and development.
- Shareholder Returns: Stock performance has been volatile, with a decline of around 50% year-to-date as of November 2023.
Growth Trajectory:
- Historical Growth: XORTX has experienced significant growth in recent years, driven by acquisitions and ZTlido® launch.
- Future Growth Projections: Future growth will depend heavily on the success of XORT development and market penetration. XORTX anticipates significant revenue growth from potential XORT commercialization starting in 2025.
Market Dynamics:
- Industry Trends: The pharmaceutical industry is experiencing a shift towards personalized medicine and targeted therapies, which aligns with XORTX's focus.
- Demand-Supply: The demand for innovative therapies for rare diseases like XLH is increasing, while the supply remains limited. XORT has the potential to fill the gap in this market.
- Technological Advancements: XORTX leverages novel drug delivery technologies, which could provide a competitive edge.
Competitors:
- XLH Treatment: Key competitors include Ultragenyx Pharmaceutical Inc. (RARE) with burosumab (Crysvita) and Idorsia Ltd. with etelcalcetide (Burosumab-first) as potential competitors.
- PHN Treatment: XORTX faces competition from various topical pain medications, including Qutenza (capsaicin) and generic lidocaine patches.
Potential Challenges and Opportunities:
- Challenges: Regulatory approval and commercialization success of XORT are crucial for the company's future. Market competition, intellectual property protection, and dependence on partner Mylan for ZTlido® distribution pose additional challenges.
- Opportunities: Positive clinical data for XORT could significantly boost market prospects. Expanding ZTlido® distribution and exploring other product opportunities can drive further growth.
AI-Based Fundamental Rating:
6/10
- Positives: Promising XORT technology, growing PHN market, and experienced leadership.
- Negatives: Lack of profitability, dependence on single product, and intense competition.
Sources and Disclaimers:
- This overview is based on data from XORTX Therapeutics Inc.'s website, investor presentations, press releases, and financial filings, as well as industry reports and news articles.
- This information should not be considered financial advice. It is essential to conduct your thorough research before making any investment decisions regarding XORTX Therapeutics Inc.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About XORTX Therapeutics Inc
Exchange | NASDAQ | Headquaters | Alberta Beach, AB, Canada |
IPO Launch date | 2018-11-28 | Founder, CEO, President & Director | Dr. Allen Warren Davidoff Ph.D. |
Sector | Healthcare | Website | https://www.xortx.com |
Industry | Biotechnology | Full time employees | 2 |
Headquaters | Alberta Beach, AB, Canada | ||
Founder, CEO, President & Director | Dr. Allen Warren Davidoff Ph.D. | ||
Website | https://www.xortx.com | ||
Website | https://www.xortx.com | ||
Full time employees | 2 |
XORTX Therapeutics Inc., a late stage clinical pharmaceutical company, engages in the development and commercialization of therapies to treat progressive kidney diseases, pre-diabetes, insulin resistance, metabolic syndrome, diabetes, diabetic nephropathy, and infection. It develops XRx-008, a late clinical stage program therapy for autosomal dominant polycystic kidney disease; XRx-101, a program to treat acute kidney injury (AKI) associated with respiratory virus infection and associated health consequences; and XRX-225, a program for treatment of type 2 diabetic nephropathy. It has a collaboration and license agreements with the Icahn School of Medicine; and a license agreement with the University of Florida Research Foundation, Inc. The company is based in Alberta Beach, Canada.
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