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GeneDx Holdings Corp. (WGS)



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Upturn Advisory Summary
03/06/2025: WGS (2-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Performance
Type Stock | Historic Profit 396.06% | Avg. Invested days 37 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 2.71B USD | Price to earnings Ratio - | 1Y Target Price 107.33 |
Price to earnings Ratio - | 1Y Target Price 107.33 | ||
Volume (30-day avg) 1282233 | Beta 1.98 | 52 Weeks Range 8.53 - 115.60 | Updated Date 03/27/2025 |
52 Weeks Range 8.53 - 115.60 | Updated Date 03/27/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.9 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -17.12% | Operating Margin (TTM) 10.98% |
Management Effectiveness
Return on Assets (TTM) -3.2% | Return on Equity (TTM) -22.1% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 2681887344 | Price to Sales(TTM) 8.86 |
Enterprise Value 2681887344 | Price to Sales(TTM) 8.86 | ||
Enterprise Value to Revenue 8.78 | Enterprise Value to EBITDA -0.83 | Shares Outstanding 28068300 | Shares Floating 18485204 |
Shares Outstanding 28068300 | Shares Floating 18485204 | ||
Percent Insiders 12.71 | Percent Institutions 88.06 |
Analyst Ratings
Rating 4 | Target Price 88 | Buy - | Strong Buy 3 |
Buy - | Strong Buy 3 | ||
Hold 3 | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
GeneDx Holdings Corp.
Company Overview
History and Background
GeneDx Holdings Corp. (formerly Sema4 Holdings Corp.) was founded in 2000 and became a public company through a reverse merger in 2021. It focuses on genomic testing to provide personalized health insights to patients and their families. Initially focused on reproductive health, they expanded to rare diseases and cancer diagnostics.
Core Business Areas
- Rare Disease Testing: Offers comprehensive genomic testing for diagnosing rare genetic disorders, helping identify causative mutations and guide treatment decisions.
- Reproductive Health Testing: Provides screening and diagnostic tests for family planning, including carrier screening, non-invasive prenatal testing (NIPT), and preimplantation genetic testing (PGT).
- Oncology Testing: Offers genomic profiling of tumors to identify actionable mutations that can inform personalized cancer treatment strategies.
Leadership and Structure
The leadership team includes prominent figures in genomics and healthcare management. The organizational structure is built around its core business segments, with dedicated teams for research and development, commercial operations, and clinical support.
Top Products and Market Share
Key Offerings
- Whole Exome Sequencing (WES): Comprehensive test that sequences all protein-coding regions of the genome. Market share is difficult to pinpoint precisely but significant within rare disease diagnostics. Competitors include Invitae (NVTA) and Labcorp (LH).
- Whole Genome Sequencing (WGS): Sequences the entire genome providing a more comprehensive analysis than WES. Market share is growing but still smaller than WES. Competitors include Illumina (ILMN) and Veritas Genetics.
- Carrier Screening: Screens individuals for genetic mutations that they could pass on to their children. Competitors include Natera (NTRA) and Myriad Genetics (MYGN).
Market Dynamics
Industry Overview
The genomic testing industry is experiencing rapid growth, driven by technological advancements, decreasing sequencing costs, and increasing demand for personalized medicine. Key trends include the adoption of WGS, liquid biopsies for cancer diagnostics, and the integration of genomic data into clinical decision-making.
Positioning
GeneDx Holdings Corp. positions itself as a leader in genomic testing, particularly in rare diseases and reproductive health. They aim to provide comprehensive and accurate results to improve patient outcomes. Competitive advantages include proprietary technology and extensive database. Market positioning is currently challenged by significant losses, raising concerns about long-term viability.
Total Addressable Market (TAM)
The global genomic testing market is estimated to reach over $62.9 billion by 2032. GeneDx aims to capture a significant portion of this market, particularly in rare disease diagnosis, carrier screening, and oncology testing. However, current losses represent a major challenge to its TAM positioning.
Upturn SWOT Analysis
Strengths
- Comprehensive genomic testing services
- Expertise in rare disease diagnostics
- Strong R&D capabilities
- Extensive genomic database
Weaknesses
- Significant net losses
- High operating expenses
- Challenging reimbursement environment
- Potential for test result misinterpretation
Opportunities
- Expanding partnerships with healthcare providers
- Developing new genomic tests
- Entering new geographic markets
- Leveraging data analytics for personalized medicine
Threats
- Intense competition
- Changing regulatory landscape
- Price pressure from insurers
- Ethical concerns surrounding genomic testing
Competitors and Market Share
Key Competitors
- Invitae (NVTA)
- Natera (NTRA)
- Myriad Genetics (MYGN)
- Illumina (ILMN)
- Exact Sciences (EXAS)
Competitive Landscape
GeneDx Holdings Corp. faces intense competition from established players with broader product portfolios and stronger financial positions. Its competitive advantages lie in its expertise in rare disease diagnostics and its extensive genomic database. However, its financial challenges hinder its ability to compete effectively.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth has been characterized by revenue growth coupled with substantial net losses.
Future Projections: Future projections depend heavily on the company's ability to reduce operating expenses and achieve profitability. Analysts' estimates vary widely.
Recent Initiatives: Recent strategic initiatives include focusing on core testing services and reducing operating costs. Streamlining operations for profitability is a key focus.
Summary
GeneDx Holdings Corp. is facing significant headwinds given continuous net losses and a challenging reimbursement environment. While its expertise in rare disease diagnostics and its extensive genomic database are key strengths, the company needs to focus on improving its financial performance and achieving profitability to remain viable. Focus on core competencies and improving efficiency are critical, but survival is not guaranteed at its current trajectory. It needs to innovate and demonstrate an ability to generate profit or the company's share price will continue to weaken.
Similar Companies
- NVTA
- NTRA
- ILMN
- EXAS
- MYGN
Sources and Disclaimers
Data Sources:
- Company filings (SEC)
- Industry reports
- Analyst estimates
Disclaimers:
This analysis is based on publicly available information and is not financial advice. Market conditions and company-specific factors can change rapidly, impacting the accuracy of this analysis.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About GeneDx Holdings Corp.
Exchange NASDAQ | Headquaters Stamford, CT, United States | ||
IPO Launch date 2020-11-04 | President, CEO & Director Ms. Katherine A. Stueland | ||
Sector Healthcare | Industry Diagnostics & Research | Full time employees 1000 | Website https://www.genedx.com |
Full time employees 1000 | Website https://www.genedx.com |
GeneDx Holdings Corp., a genomics company, provides genetic testing services. It primarily offers pediatric and rare disease diagnostics with a focus on whole exome and genome sequencing, as well as data and information services. The company is headquartered in Stamford, Connecticut.
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