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WGS
Upturn stock ratingUpturn stock rating

GeneDx Holdings Corp. (WGS)

Upturn stock ratingUpturn stock rating
$97.27
Delayed price
Profit since last BUY-4.24%
upturn advisory
Consider higher Upturn Star rating
BUY since 11 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

03/06/2025: WGS (2-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

AI Based Fundamental Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type Stock
Historic Profit 396.06%
Avg. Invested days 37
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 5.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 03/06/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 2.71B USD
Price to earnings Ratio -
1Y Target Price 107.33
Price to earnings Ratio -
1Y Target Price 107.33
Volume (30-day avg) 1282233
Beta 1.98
52 Weeks Range 8.53 - 115.60
Updated Date 03/27/2025
52 Weeks Range 8.53 - 115.60
Updated Date 03/27/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.9

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -17.12%
Operating Margin (TTM) 10.98%

Management Effectiveness

Return on Assets (TTM) -3.2%
Return on Equity (TTM) -22.1%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 2681887344
Price to Sales(TTM) 8.86
Enterprise Value 2681887344
Price to Sales(TTM) 8.86
Enterprise Value to Revenue 8.78
Enterprise Value to EBITDA -0.83
Shares Outstanding 28068300
Shares Floating 18485204
Shares Outstanding 28068300
Shares Floating 18485204
Percent Insiders 12.71
Percent Institutions 88.06

Analyst Ratings

Rating 4
Target Price 88
Buy -
Strong Buy 3
Buy -
Strong Buy 3
Hold 3
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

GeneDx Holdings Corp.

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Company Overview

History and Background

GeneDx Holdings Corp. (formerly Sema4 Holdings Corp.) was founded in 2000 and became a public company through a reverse merger in 2021. It focuses on genomic testing to provide personalized health insights to patients and their families. Initially focused on reproductive health, they expanded to rare diseases and cancer diagnostics.

Core Business Areas

  • Rare Disease Testing: Offers comprehensive genomic testing for diagnosing rare genetic disorders, helping identify causative mutations and guide treatment decisions.
  • Reproductive Health Testing: Provides screening and diagnostic tests for family planning, including carrier screening, non-invasive prenatal testing (NIPT), and preimplantation genetic testing (PGT).
  • Oncology Testing: Offers genomic profiling of tumors to identify actionable mutations that can inform personalized cancer treatment strategies.

Leadership and Structure

The leadership team includes prominent figures in genomics and healthcare management. The organizational structure is built around its core business segments, with dedicated teams for research and development, commercial operations, and clinical support.

Top Products and Market Share

Key Offerings

  • Whole Exome Sequencing (WES): Comprehensive test that sequences all protein-coding regions of the genome. Market share is difficult to pinpoint precisely but significant within rare disease diagnostics. Competitors include Invitae (NVTA) and Labcorp (LH).
  • Whole Genome Sequencing (WGS): Sequences the entire genome providing a more comprehensive analysis than WES. Market share is growing but still smaller than WES. Competitors include Illumina (ILMN) and Veritas Genetics.
  • Carrier Screening: Screens individuals for genetic mutations that they could pass on to their children. Competitors include Natera (NTRA) and Myriad Genetics (MYGN).

Market Dynamics

Industry Overview

The genomic testing industry is experiencing rapid growth, driven by technological advancements, decreasing sequencing costs, and increasing demand for personalized medicine. Key trends include the adoption of WGS, liquid biopsies for cancer diagnostics, and the integration of genomic data into clinical decision-making.

Positioning

GeneDx Holdings Corp. positions itself as a leader in genomic testing, particularly in rare diseases and reproductive health. They aim to provide comprehensive and accurate results to improve patient outcomes. Competitive advantages include proprietary technology and extensive database. Market positioning is currently challenged by significant losses, raising concerns about long-term viability.

Total Addressable Market (TAM)

The global genomic testing market is estimated to reach over $62.9 billion by 2032. GeneDx aims to capture a significant portion of this market, particularly in rare disease diagnosis, carrier screening, and oncology testing. However, current losses represent a major challenge to its TAM positioning.

Upturn SWOT Analysis

Strengths

  • Comprehensive genomic testing services
  • Expertise in rare disease diagnostics
  • Strong R&D capabilities
  • Extensive genomic database

Weaknesses

  • Significant net losses
  • High operating expenses
  • Challenging reimbursement environment
  • Potential for test result misinterpretation

Opportunities

  • Expanding partnerships with healthcare providers
  • Developing new genomic tests
  • Entering new geographic markets
  • Leveraging data analytics for personalized medicine

Threats

  • Intense competition
  • Changing regulatory landscape
  • Price pressure from insurers
  • Ethical concerns surrounding genomic testing

Competitors and Market Share

Key Competitors

  • Invitae (NVTA)
  • Natera (NTRA)
  • Myriad Genetics (MYGN)
  • Illumina (ILMN)
  • Exact Sciences (EXAS)

Competitive Landscape

GeneDx Holdings Corp. faces intense competition from established players with broader product portfolios and stronger financial positions. Its competitive advantages lie in its expertise in rare disease diagnostics and its extensive genomic database. However, its financial challenges hinder its ability to compete effectively.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been characterized by revenue growth coupled with substantial net losses.

Future Projections: Future projections depend heavily on the company's ability to reduce operating expenses and achieve profitability. Analysts' estimates vary widely.

Recent Initiatives: Recent strategic initiatives include focusing on core testing services and reducing operating costs. Streamlining operations for profitability is a key focus.

Summary

GeneDx Holdings Corp. is facing significant headwinds given continuous net losses and a challenging reimbursement environment. While its expertise in rare disease diagnostics and its extensive genomic database are key strengths, the company needs to focus on improving its financial performance and achieving profitability to remain viable. Focus on core competencies and improving efficiency are critical, but survival is not guaranteed at its current trajectory. It needs to innovate and demonstrate an ability to generate profit or the company's share price will continue to weaken.

Similar Companies

  • NVTA
  • NTRA
  • ILMN
  • EXAS
  • MYGN

Sources and Disclaimers

Data Sources:

  • Company filings (SEC)
  • Industry reports
  • Analyst estimates

Disclaimers:

This analysis is based on publicly available information and is not financial advice. Market conditions and company-specific factors can change rapidly, impacting the accuracy of this analysis.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About GeneDx Holdings Corp.

Exchange NASDAQ
Headquaters Stamford, CT, United States
IPO Launch date 2020-11-04
President, CEO & Director Ms. Katherine A. Stueland
Sector Healthcare
Industry Diagnostics & Research
Full time employees 1000
Full time employees 1000

GeneDx Holdings Corp., a genomics company, provides genetic testing services. It primarily offers pediatric and rare disease diagnostics with a focus on whole exome and genome sequencing, as well as data and information services. The company is headquartered in Stamford, Connecticut.

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