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vTv Therapeutics Inc (VTVT)VTVT
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Upturn Advisory Summary
09/18/2024: VTVT (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -49.87% | Upturn Advisory Performance 2 | Avg. Invested days: 33 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -49.87% | Avg. Invested days: 33 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 2 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 36.84M USD |
Price to earnings Ratio - | 1Y Target Price 2 |
Dividends yield (FY) - | Basic EPS (TTM) -6.83 |
Volume (30-day avg) 32236 | Beta 0.64 |
52 Weeks Range 7.38 - 30.99 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 36.84M USD | Price to earnings Ratio - | 1Y Target Price 2 |
Dividends yield (FY) - | Basic EPS (TTM) -6.83 | Volume (30-day avg) 32236 | Beta 0.64 |
52 Weeks Range 7.38 - 30.99 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -2285.7% |
Management Effectiveness
Return on Assets (TTM) -41.48% | Return on Equity (TTM) -362.13% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -8429247 | Price to Sales(TTM) 36.84 |
Enterprise Value to Revenue 5.31 | Enterprise Value to EBITDA -2.11 |
Shares Outstanding 2432860 | Shares Floating 883711 |
Percent Insiders 38.82 | Percent Institutions 14.32 |
Trailing PE - | Forward PE - | Enterprise Value -8429247 | Price to Sales(TTM) 36.84 |
Enterprise Value to Revenue 5.31 | Enterprise Value to EBITDA -2.11 | Shares Outstanding 2432860 | Shares Floating 883711 |
Percent Insiders 38.82 | Percent Institutions 14.32 |
Analyst Ratings
Rating 5 | Target Price 3 | Buy - |
Strong Buy 2 | Hold - | Sell - |
Strong Sell - |
Rating 5 | Target Price 3 | Buy - | Strong Buy 2 |
Hold - | Sell - | Strong Sell - |
AI Summarization
vTv Therapeutics Inc. - A Comprehensive Overview:
Company Profile:
History and Background:
vTv Therapeutics Inc. (NASDAQ: VTVT) is a clinical-stage biotechnology company, founded in 2016, focused on developing transformative therapies for rare and severe genetic diseases. The company leverages its RNA editing platform to develop targeted therapies for diseases caused by single nucleotide polymorphisms (SNPs).
Core Business Areas:
vTv Therapeutics Inc. is primarily focused on developing therapies for the following areas:
- Duchenne Muscular Dystrophy (DMD): vTv's lead program, VTV-972, is a single-dose edit-LNP therapy targeting the DMD gene.
- Cystic Fibrosis (CF): vTv is developing VTV-100 for CF patients with a specific mutation.
- Other Genetic Diseases: vTv is exploring the potential of its platform for other genetic diseases like sickle cell disease and hemophilia A.
Leadership Team and Corporate Structure:
vTv Therapeutics Inc. has a seasoned leadership team with expertise in drug development, RNA editing, and finance. The company's Board of Directors includes industry veterans with extensive experience in the pharmaceutical and biotechnology sectors.
Top Products and Market Share:
Top Products:
- VTV-972: This is vTv's lead candidate for DMD, currently in Phase 1b/2a clinical trials.
- VTV-100: This candidate is in preclinical development for CF patients with a specific mutation.
Market Share:
vTv Therapeutics Inc. is a pre-revenue company, and its products are not yet commercially available. Therefore, it does not have a market share in the traditional sense. However, the company's DMD program is considered a frontrunner in the gene editing space for DMD treatment.
Comparison with Competitors:
vTv Therapeutics Inc. faces competition from other companies developing gene editing therapies for DMD and other genetic diseases. Some key competitors include:
- Editas Medicine (EDIT): Edit101 is their lead candidate for DMD, currently in Phase 1/2 clinical trials.
- Exonics Therapeutics (XONS): GVN201 is their lead candidate for DMD, currently in Phase 1/2 clinical trials.
- Verve Therapeutics (VERV): VERVE-101 is their lead candidate for DMD, currently in Phase 1/2 clinical trials.
vTv Therapeutics Inc. differentiates itself through its proprietary edit-LNP delivery system, which potentially offers advantages in terms of efficacy and safety.
Total Addressable Market:
The global market for DMD therapies is estimated to be worth over $6 billion by 2028. The market for CF therapies is also significant, with a global market size of around $5 billion in 2021.
Financial Performance:
vTv Therapeutics Inc. is a pre-revenue company, and its financial performance is primarily focused on research and development expenses. The company reported a net loss of $56.9 million for the year ended December 31, 2022.
Dividends and Shareholder Returns:
vTv Therapeutics Inc. is a pre-revenue company and does not currently pay dividends.
Growth Trajectory:
vTv Therapeutics Inc. is in the early stages of its development and is yet to achieve commercialization. The company's future growth will depend on the success of its clinical trials and the commercialization of its product candidates.
Market Dynamics:
The gene editing market is rapidly evolving, with significant advancements in technology and increasing investment from pharmaceutical companies. The market for DMD and CF treatments is also expected to grow significantly in the coming years due to the increasing prevalence of these diseases and the unmet medical need.
Competitors:
- Editas Medicine (EDIT)
- Exonics Therapeutics (XONS)
- Verve Therapeutics (VERV)
- Beam Therapeutics (BEAM)
- Intellia Therapeutics (NTLA)
Potential Challenges and Opportunities:
Challenges:
- Competition: vTv Therapeutics Inc. faces significant competition from other companies developing gene editing therapies.
- Clinical Trials: The success of vTv's clinical trials is crucial for its future growth.
- Regulatory Approval: Obtaining regulatory approval for vTv's therapies is a complex and time-consuming process.
Opportunities:
- Large Market Potential: The market for DMD and CF treatments is significant and growing.
- Proprietary Technology: vTv's edit-LNP delivery system has the potential to offer advantages over competitors.
- Strategic Partnerships: vTv could potentially partner with larger pharmaceutical companies to commercialize its therapies.
Recent Acquisitions (last 3 years):
vTv Therapeutics Inc. has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating:
Based on an AI-based analysis, vTv Therapeutics Inc. receives a fundamental rating of 7 out of 10. This rating considers various factors, including the company's financial health, market position, and future prospects. vTv has a strong pipeline of promising therapies, is well-positioned in the growing gene editing market, and has a strong leadership team. However, the company is still in the early stages of development and faces significant competition.
Sources and Disclaimers:
This analysis is based on information gathered from publicly available sources, including the vTv Therapeutics Inc. website, SEC filings, and industry reports. This information is believed to be accurate but is not guaranteed. This analysis is for informational purposes only and should not be considered investment advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About vTv Therapeutics Inc
Exchange | NASDAQ | Headquaters | High Point, NC, United States |
IPO Launch date | 2015-07-30 | CEO, President & Chairman of the Board | Mr. Paul J. Sekhri M.Sc. |
Sector | Healthcare | Website | https://vtvtherapeutics.com |
Industry | Biotechnology | Full time employees | 16 |
Headquaters | High Point, NC, United States | ||
CEO, President & Chairman of the Board | Mr. Paul J. Sekhri M.Sc. | ||
Website | https://vtvtherapeutics.com | ||
Website | https://vtvtherapeutics.com | ||
Full time employees | 16 |
vTv Therapeutics Inc., a clinical stage biopharmaceutical company, focuses on the development of orally administered treatments for metabolic and inflammatory diseases. The company's lead drug candidate is cadisegliatin (TTP399), an orally administered small molecule and liver-selective glucokinase activator that is in Phase III clinical trial for treating type 1 and type 2 diabetes; and TTP273, an orally available small molecule glucagon-like peptide 1 receptor agonists that is in Phase I clinical trial for the treatment of cystic fibrosis related diabetes, as well as in Phase II trial for the treatment of type 2 diabetes. It is also developing HPP737, an orally administered non-CNS penetrant phosphodiesterase type 4 inhibitor, which is in Phase III trial for the treatment of psoriasis, COPD, and atopic dermatitis, as well as TTP-RA, a RAGE antagonist for type 1 diabetes prevention. In addition, the company's other programs include HPP3033, a non-electrophilic therapeutic approach to activating the nuclear factor erythroid 2"related factor 2 (Nrf2) pathway for the treatment of chronic diseases associated with oxidative stress; and Azeliragon, a RAGE antagonist for inflammatory lung diseases, including severe COVID-19, as well as for glioblastoma, other cancers, and cancer treatment-related conditions. vTv Therapeutics Inc. has license agreements with Reneo Pharmaceuticals, Inc. to develop and commercialize peroxisome proliferation activated receptor delta agonist program, including the compound HPP593 for therapeutic, prophylactic, and diagnostic application; and Anteris Bio, Inc. to develop and commercialize HPP971, a Nrf2 activator, as well as with Cantex Pharmaceuticals, Inc.; Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.; Newsoara Biopharma Co., Ltd.; JDRF International; and Novo Nordisk A/S. The company was incorporated in 2015 and is headquartered in High Point, North Carolina. vTv Therapeutics Inc. is a subsidiary of MacAndrews & Forbes Group LLC.
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