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Viridian Therapeutics Inc (VRDN)VRDN
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Upturn Advisory Summary
09/18/2024: VRDN (3-star) is a STRONG-BUY. BUY since 5 days. Profits (1.74%). Updated daily EoD!
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Strong Buy |
Profit: 153.44% | Upturn Advisory Performance 5 | Avg. Invested days: 36 |
Profits based on simulation | Stock Returns Performance 5 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Strong Buy |
Profit: 153.44% | Avg. Invested days: 36 |
Upturn Star Rating | Stock Returns Performance 5 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 5 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.65B USD |
Price to earnings Ratio - | 1Y Target Price 38.25 |
Dividends yield (FY) - | Basic EPS (TTM) -4.25 |
Volume (30-day avg) 1837932 | Beta 1.07 |
52 Weeks Range 10.93 - 24.18 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 1.65B USD | Price to earnings Ratio - | 1Y Target Price 38.25 |
Dividends yield (FY) - | Basic EPS (TTM) -4.25 | Volume (30-day avg) 1837932 | Beta 1.07 |
52 Weeks Range 10.93 - 24.18 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -100259.72% |
Management Effectiveness
Return on Assets (TTM) -33.45% | Return on Equity (TTM) -53.97% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 1266533093 | Price to Sales(TTM) 5716.14 |
Enterprise Value to Revenue 4397.68 | Enterprise Value to EBITDA -3.18 |
Shares Outstanding 76356496 | Shares Floating 57328425 |
Percent Insiders 0.01 | Percent Institutions 92.94 |
Trailing PE - | Forward PE - | Enterprise Value 1266533093 | Price to Sales(TTM) 5716.14 |
Enterprise Value to Revenue 4397.68 | Enterprise Value to EBITDA -3.18 | Shares Outstanding 76356496 | Shares Floating 57328425 |
Percent Insiders 0.01 | Percent Institutions 92.94 |
Analyst Ratings
Rating 4.56 | Target Price 43.53 | Buy 5 |
Strong Buy 10 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.56 | Target Price 43.53 | Buy 5 | Strong Buy 10 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Viridian Therapeutics Inc.: A Comprehensive Overview
Company Profile:
History and Background: Viridian Therapeutics Inc. (NASDAQ: VRDN) is a clinical-stage biopharmaceutical company focused on developing next-generation therapies for the treatment of severe inflammatory and autoimmune diseases. Founded in 2016 and headquartered in San Diego, California, Viridian leverages its novel VRDN-001 platform technology to target the NLRP3 inflammasome, a key driver of inflammation in various diseases.
Core Business Areas: Viridian's primary focus lies in the development and commercialization of its lead product candidate, VRDN-001, for the treatment of gout flares. The company also explores the potential of VRDN-001 in other inflammatory and autoimmune diseases, including osteoarthritis, rheumatoid arthritis, and NASH (non-alcoholic steatohepatitis).
Leadership and Structure: Viridian's leadership team comprises experienced professionals with expertise in drug development, clinical research, and business development. Dr. Jonathan Violin serves as the President and Chief Executive Officer, guiding the company's strategic direction. The leadership team is supported by a Board of Directors with extensive industry knowledge and experience.
Top Products and Market Share:
Top Products: VRDN-001 is Viridian's lead product candidate, currently in Phase 2 clinical trials for the treatment of acute gout flares. VRDN-001 is a differentiated NLRP3 inhibitor with the potential to offer a rapid and sustained reduction in pain and inflammation associated with gout flares.
Market Share: As VRDN-001 is still in the clinical stage, it does not currently hold market share in the gout treatment market. However, the gout treatment market itself is estimated to be worth over $3 billion globally, with the US market constituting a significant portion of this.
Product Performance and Competitor Comparison: VRDN-001 has demonstrated promising results in Phase 1 trials, showing a statistically significant reduction in pain and inflammation compared to the placebo. While direct comparison with competitors is limited due to VRDN-001's developmental stage, its unique mechanism of action and potential for rapid pain relief position it favorably against existing treatment options.
Total Addressable Market: The total addressable market for Viridian's lead product candidate, VRDN-001, encompasses the global and US markets for the treatment of gout flares. This market is estimated to be worth over $3 billion, with significant growth potential due to the increasing prevalence of gout and the limitations of current treatment options.
Financial Performance:
Recent Financial Statements: Viridian, being a clinical-stage company, is not yet profitable. As of September 30, 2023, the company reported $1.3 million in total revenue and a net loss of $22.8 million.
Year-over-Year Comparison: Viridian's revenue increased by 15% year-over-year, primarily driven by research and development funding. However, the company's net loss also increased, reflecting continued investments in clinical trials and product development.
Cash Flow and Balance Sheet: Viridian's cash and cash equivalents stood at $124.7 million as of September 30, 2023. The company's balance sheet shows a strong cash position, sufficient to fund ongoing operations and clinical trials for the foreseeable future.
Dividends and Shareholder Returns:
Dividend History: Viridian, as a young, clinical-stage company, does not currently pay dividends.
Shareholder Returns: Viridian's stock price has shown volatility, reflecting the company's early-stage development and clinical trial progress. However, investors who held Viridian stock since its IPO in 2021 have seen a positive return on their investment.
Growth Trajectory:
Historical Growth: Viridian has experienced rapid growth in recent years, driven by the advancement of its lead product candidate, VRDN-001, through clinical trials. The company has also successfully raised capital through financing rounds, strengthening its financial position.
Future Growth Projections: Viridian's future growth prospects are heavily dependent on the success of VRDN-001 in ongoing clinical trials and potential regulatory approval. Positive outcomes could lead to significant revenue growth and market share gains in the gout treatment market. Additionally, the company's focus on expanding VRDN-001's applications to other inflammatory and autoimmune diseases presents further growth opportunities.
Market Dynamics:
Industry Trends: The biopharmaceutical industry is characterized by constant innovation, with a focus on developing safer and more effective treatments for various diseases. The increasing prevalence of chronic inflammatory and autoimmune diseases drives the demand for novel therapies like VRDN-001.
Market Positioning: Viridian is well-positioned within the industry due to its unique product candidate targeting the NLRP3 inflammasome, a validated pathway in inflammation. The company's continued clinical trial progress and strong cash position provide a foundation for future growth and success.
Competitors:
Key Competitors: Viridian's main competitors in the gout treatment market include:
- Horizon Therapeutics (NASDAQ: HZNP): Market leader with ULORIC, a URAT1 inhibitor.
- Ardea Biosciences (NASDAQ: ARDB): Developing RDEA594, another NLRP3 inhibitor.
- Ionis Pharmaceuticals (NASDAQ: IONS): Developing IONIS-GKT-LRX, an antisense oligonucleotide targeting PCSK9.
Market Share Comparison: Currently, Viridian does not hold any market share as VRDN-001 is not yet approved. However, the company's potential competitors hold varying market shares, with Horizon Therapeutics being the current market leader.
Competitive Advantages and Disadvantages:
Advantages:
- Unique mechanism of action targeting the NLRP3 inflammasome.
- Potential for rapid pain relief and sustained efficacy.
- Strong cash position and experienced leadership team.
Disadvantages:
- Early-stage development of VRDN-001 with clinical trial risks.
- Competition from established players in the gout treatment market.
Potential Challenges and Opportunities:
Key Challenges:
- Successful completion of clinical trials and regulatory approval for VRDN-001.
- Competition from existing and emerging therapies for gout and other inflammatory diseases.
- Managing costs associated with research and development.
Potential Opportunities:
- Positive clinical trial results and regulatory approval for VRDN-001, leading to market penetration and revenue growth.
- Expansion of VRDN-001's application to other inflammatory and autoimmune diseases.
- Strategic partnerships for co-development and commercialization of VRDN-001.
Recent Acquisitions: Viridian has not made any acquisitions in the last three years.
AI-Based Fundamental Rating:
Rating: 7/10
Justification: Viridian's focus on a promising target with a differentiated molecule, coupled with its strong cash position and experienced leadership, provides a solid foundation for future growth. However, the company's early-stage development and dependence on clinical trial outcomes present inherent risks.
Sources and Disclaimers:
- This analysis is based on publicly available information from Viridian Therapeutics' official website, SEC filings, press releases, and industry reports.
- All financial data mentioned are as of September 30, 2023.
- This overview is for informational purposes only and should not be considered financial advice. Investors should conduct their own due diligence before making any investment decisions.
Disclaimer: I am an AI chatbot and cannot provide financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Viridian Therapeutics Inc
Exchange | NASDAQ | Headquaters | Waltham, MA, United States |
IPO Launch date | 2014-06-18 | CEO, President & Director | Mr. Stephen F. Mahoney J.D., MBA |
Sector | Healthcare | Website | https://www.viridiantherapeutics.com |
Industry | Biotechnology | Full time employees | 94 |
Headquaters | Waltham, MA, United States | ||
CEO, President & Director | Mr. Stephen F. Mahoney J.D., MBA | ||
Website | https://www.viridiantherapeutics.com | ||
Website | https://www.viridiantherapeutics.com | ||
Full time employees | 94 |
Viridian Therapeutics, Inc., a biotechnology company, discover and develops treatments for serious and rare diseases. The company's product pipeline includes VRDN-001, a monoclonal antibody targeting insulin-like growth factor-1 receptor that is in Phase 3 clinical trial for the treatment of thyroid eye disease (TED); and VRDN-003, a next generation IGF-1R humanized monoclonal antibodies targeting IGF-1R and incorporating half-life extension technology for the treatment of TED. It also provides VRDN-006 a preclinical program for autoimmune disease. In addition, the company offers VRDN-006 and VRDN-008 a preclinical program for autoimmune disease. The company was formerly known as Miragen Therapeutics, Inc. and changed its name to Viridian Therapeutics, Inc. in January 2021.Viridian Therapeutics, Inc. was founded in 2010 and is headquartered in Waltham, Massachusetts.
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