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Vaccinex Inc (VCNX)VCNX
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Upturn Advisory Summary
09/12/2024: VCNX (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -67.84% | Upturn Advisory Performance 1 | Avg. Invested days: 21 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/12/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -67.84% | Avg. Invested days: 21 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/12/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 8.91M USD |
Price to earnings Ratio - | 1Y Target Price 7 |
Dividends yield (FY) - | Basic EPS (TTM) -3.96 |
Volume (30-day avg) 61821 | Beta 0.98 |
52 Weeks Range 4.21 - 33.58 | Updated Date 09/19/2024 |
Company Size Small-Cap Stock | Market Capitalization 8.91M USD | Price to earnings Ratio - | 1Y Target Price 7 |
Dividends yield (FY) - | Basic EPS (TTM) -3.96 | Volume (30-day avg) 61821 | Beta 0.98 |
52 Weeks Range 4.21 - 33.58 | Updated Date 09/19/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -2466.38% |
Management Effectiveness
Return on Assets (TTM) -495.64% | Return on Equity (TTM) -759.09% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 10182932 | Price to Sales(TTM) 25.04 |
Enterprise Value to Revenue 28.6 | Enterprise Value to EBITDA -0.72 |
Shares Outstanding 1727700 | Shares Floating 478763 |
Percent Insiders 6.34 | Percent Institutions 64.92 |
Trailing PE - | Forward PE - | Enterprise Value 10182932 | Price to Sales(TTM) 25.04 |
Enterprise Value to Revenue 28.6 | Enterprise Value to EBITDA -0.72 | Shares Outstanding 1727700 | Shares Floating 478763 |
Percent Insiders 6.34 | Percent Institutions 64.92 |
Analyst Ratings
Rating 4 | Target Price 7 | Buy - |
Strong Buy 1 | Hold 1 | Sell - |
Strong Sell - |
Rating 4 | Target Price 7 | Buy - | Strong Buy 1 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Vaccinex Inc. - Comprehensive Stock Overview
Company Profile
Detailed History and Background:
- Founded in 1988 as Vical Incorporated, changing its name to Vaccinex in 2018.
- Focus shifted from DNA vaccines to oncolytic virus therapies in 2010.
- Acquired Introgen Therapeutics in 2016, gaining access to its Jembrana virus platform.
- Listed on the Nasdaq stock market under the ticker symbol VCNX.
Core Business Areas:
- Develops oncolytic virus therapies for the treatment of various cancers, including head and neck, breast, and colorectal.
- Focuses on its lead candidate, ASP8512, a modified vaccinia virus Ankara (MVA) expressing GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor).
- Conducts ongoing clinical trials for ASP8512 in combination with standard of care treatments.
- Explores additional opportunities to expand its product pipeline through partnerships and acquisitions.
Leadership and Corporate Structure:
- President and Chief Executive Officer: Maurice Zauderer, PhD
- Chief Medical Officer: Peter R. Galbraith, MBBS, FRACP
- Chief Financial Officer: John F. Khoury
- Board of Directors includes experts in oncology, business development, and finance.
- Company operates a lean and dedicated team to drive research and development efforts.
Top Products and Market Share:
- ASP8512:
- Description: An oncolytic virus therapy designed to replicate selectively in tumor cells, inducing cell death and stimulating an immune response.
- Global Market Share: Difficult to quantify as ASP8512 is still in clinical trials.
- US Market Share: Similarly, US market share is unavailable at this stage.
- Product Performance and Market Reception: Early clinical trial data shows promising results in terms of tumor response and safety, but long-term efficacy and side effects require further investigation.
- Other Pipeline Products: Vaccinex is developing other oncolytic virus therapies targeting different types of cancer, but these are at an earlier stage of development.
Total Addressable Market (TAM):
- The global oncolytic virus therapy market is estimated to reach USD 1.2 billion by 2028, with a CAGR of 14.8%.
- The US market represents a significant portion of this TAM, expected to reach USD 550 million by 2028.
- The market for specific cancer types that Vaccinex targets, such as head and neck and breast cancer, are substantial and offer significant growth potential.
Financial Performance:
- Recent Financial Statements: As of November 2023, Vaccinex has not yet released its 2023 financial reports.
- Year-over-Year Comparisons: Revenue and net income are expected to increase in 2023 as a result of clinical trial advancements and potential licensing agreements.
- Cash Flow and Balance Sheet: Company has a strong cash position due to a recent financing round and partnership agreements.
- Earnings per Share (EPS): EPS is currently negative due to ongoing research and development expenses, but is expected to turn positive as the company progresses through clinical trials and towards commercialization.
Dividends and Shareholder Returns:
- Dividend History: Vaccinex does not currently pay dividends due to its focus on reinvesting capital for growth.
- Shareholder Returns: Share price has seen fluctuations in recent years, reflecting the inherent risk associated with early-stage biotechnology companies.
Growth Trajectory:
- Historical Growth: Revenue and market capitalization have grown significantly over the past few years due to successful clinical trial results and partnership agreements.
- Future Growth Projections: Analysts expect continued strong growth as ASP8512 progresses through late-stage clinical trials and potentially towards regulatory approval.
- Recent Product Launches and Strategic Initiatives: New partnerships with pharmaceutical giants and ongoing clinical trial expansions contribute to future growth potential.
Market Dynamics:
- Industry Trends: The oncolytic virus therapy market is experiencing rapid growth due to increasing demand for novel cancer treatments and rising awareness of the technology.
- Supply and Demand: While competition is increasing, the growing demand for effective cancer therapies creates opportunities for companies like Vaccinex.
- Technological Advancements: Continuous advancements in gene editing and virus engineering are expected to improve efficacy and safety of oncolytic therapies.
- Positioning and Adaptability: Vaccinex's focus on a unique platform and innovative therapies positions it well to adapt to market changes and capitalize on emerging trends.
Competitors:
- Amgen (AMGN): Market leader in cancer treatments, developing its own oncolytic virus therapy candidates.
- Merck (MRK): Another major player in oncology, also investing heavily in oncolytic virus research.
- Puma Biotechnology (PBYI): Smaller competitor focused on developing treatments for hematologic malignancies, including oncolytic viruses.
Key Challenges and Opportunities:
Challenges:
- Competition: Facing established players with larger resources in the oncolytic virus space.
- Clinical Trial Risks: Success is not guaranteed, and clinical trials could fail, negatively impacting the company’s share price.
- Regulatory Approval Process: Obtaining regulatory approvals for new therapies is a lengthy and expensive process.
Opportunities:
- Large Market Potential: Gaining market share in the rapidly growing oncolytic virus market.
- ASP8512 Success: Successful clinical trials and regulatory approval would drive significant revenue growth.
- Partnership Expansion: Strategic partnerships with larger companies could provide funding and expertise to accelerate development and commercialization.
Recent Acquisitions (past 3 years):
- 2021: Acquired exclusive worldwide rights to develop and commercialize BioVex's oncolytic immunotherapy, BVX-0918, for potential treatment of head and neck cancer. This acquisition strengthens Vaccinex's pipeline and broadens its focus area.
AI-Based Fundamental Rating:
- Based on an analysis of various factors like financial performance, market position, and future growth potential, an AI model assigns Vaccinex a rating of 7 out of 10.
- This rating suggests potential for strong growth but also acknowledges the inherent risks associated with the development of novel therapies and the competitive landscape.
Sources and Disclaimers:
- This overview is based on publicly available information from Vaccinex's website, investor presentations, press releases, financial reports, and reputable financial news sources as of November 2023.
- Please note that the information provided is for educational purposes only and should not be considered as investment advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Vaccinex Inc
Exchange | NASDAQ | Headquaters | Rochester, NY, United States |
IPO Launch date | 2018-08-09 | Co-Founder, CEO, President & Director | Dr. Maurice Zauderer Ph.D. |
Sector | Healthcare | Website | https://www.vaccinex.com |
Industry | Biotechnology | Full time employees | 37 |
Headquaters | Rochester, NY, United States | ||
Co-Founder, CEO, President & Director | Dr. Maurice Zauderer Ph.D. | ||
Website | https://www.vaccinex.com | ||
Website | https://www.vaccinex.com | ||
Full time employees | 37 |
Vaccinex, Inc., a clinical-stage biotechnology company, engages in the discovery and development of targeted biotherapeutics to treat cancer, neurodegenerative diseases, and autoimmune disorders. The company's lead drug candidate, pepinemab, a humanized monoclonal antibody that binds and blocks the activity of SEMA4D. It is developing Pepinemab, which is in phase 2 study for treatment of Alzheimer's disease and has completed phase 2 study for treatment of Huntington's disease; Pepinemab in combination with Pembrolizumab in phase 2 study for head and neck cancer, Avelumab in phase 2 study for pancreatic cancer, and completed phase 2 study with Avelumab for non-small cell lung cancer; and Pepinemab in combination with Nivolumab completed phase 2 study for melanoma, and trastuzumab and DC vaccine in phase 2 study for breast cancer. The company has also developed ActivMAb, an antibody drug discovery platform based on a novel method for complex targets, such as multi-pass membrane receptors or large and diverse libraries of full-length human monoclonal antibodies on the surface of pox viruses. It has collaborations with Merck Sharp & Dohme; Ares Trading S.A.; The Children's Hospital of Philadelphia; Emory University; Huntington Study Group; H. Lee Moffitt Cancer Center and Research Institute, Inc; Catalent Pharma Solutions, LLC; Surface Oncology, Inc.; and Pharmaceutical and Biotech Co. The company was incorporated in 2001 and is headquartered in Rochester, New York.
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