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TYRA
Upturn stock ratingUpturn stock rating

Tyra Biosciences Inc (TYRA)

Upturn stock ratingUpturn stock rating
$7.74
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

04/04/2025: TYRA (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -73.91%
Avg. Invested days 24
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/04/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 410.92M USD
Price to earnings Ratio -
1Y Target Price 30
Price to earnings Ratio -
1Y Target Price 30
Volume (30-day avg) 337211
Beta 1.19
52 Weeks Range 7.52 - 29.60
Updated Date 04/6/2025
52 Weeks Range 7.52 - 29.60
Updated Date 04/6/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.51

Earnings Date

Report Date 2025-03-28
When -
Estimate -0.4671
Actual -0.43

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -22.09%
Return on Equity (TTM) -31.6%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 75697267
Price to Sales(TTM) -
Enterprise Value 75697267
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -6.95
Shares Outstanding 53090000
Shares Floating 21075120
Shares Outstanding 53090000
Shares Floating 21075120
Percent Insiders 4.17
Percent Institutions 95.73

Analyst Ratings

Rating 4.71
Target Price 30.57
Buy 2
Strong Buy 5
Buy 2
Strong Buy 5
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Tyra Biosciences Inc

stock logo

Company Overview

overview logo History and Background

Tyra Biosciences, Inc. is a precision oncology company founded in 2018. It focuses on developing therapies to overcome tumor resistance and improve outcomes for cancer patients. It has rapidly progressed through preclinical stages to clinical trials with its lead programs.

business area logo Core Business Areas

  • Drug Discovery and Development: Focuses on discovering and developing small molecule therapeutics targeting specific cancer-driving mutations.
  • Precision Oncology: Develops therapies based on a deep understanding of the molecular basis of cancer and patient stratification.
  • Clinical Trials: Conducts clinical trials to evaluate the safety and efficacy of its drug candidates.

leadership logo Leadership and Structure

The leadership team consists of experienced executives in drug development and oncology. The organizational structure typically includes departments for research, development, clinical operations, and business development.

Top Products and Market Share

overview logo Key Offerings

  • TYRA-300: An FGFR3-selective inhibitor targeting advanced urothelial carcinoma and other FGFR3-altered cancers. It is in clinical trials. Competitors include FGFR inhibitors developed by Johnson & Johnson (erdafitinib - Balversa) and others. Market share data is currently not available as TYRA-300 is in clinical development.
  • TYRA-200: Next generation RET inhibitor. Competitors include Eli Lilly's Retevmo (selpercatinib) and Blueprint Medicines' Gavreto (pralsetinib). Market share data is currently not available as TYRA-200 is in preclinical development.

Market Dynamics

industry overview logo Industry Overview

The oncology drug market is a large and rapidly growing market driven by increasing cancer incidence and advancements in cancer therapies. Precision oncology is a growing segment, focusing on targeted therapies for specific genetic mutations.

Positioning

Tyra Biosciences is positioned as a precision oncology company developing novel small molecule therapeutics. Its competitive advantage lies in its focus on overcoming drug resistance and its expertise in kinase inhibitor design.

Total Addressable Market (TAM)

The TAM for targeted cancer therapies is significant, estimated to be in the tens of billions of dollars. Tyra is positioning itself to capture a share of this market by developing targeted therapies for specific patient populations with unmet needs.

Upturn SWOT Analysis

Strengths

  • Strong focus on precision oncology and targeted therapies
  • Experienced management team
  • Proprietary drug discovery platform
  • Focus on overcoming drug resistance

Weaknesses

  • Limited clinical data to date
  • Dependence on successful clinical trials
  • High R&D expenses
  • Relatively small company size

Opportunities

  • Potential to develop first-in-class or best-in-class therapies
  • Expansion into new cancer indications
  • Partnerships with larger pharmaceutical companies
  • Advancements in cancer diagnostics and patient stratification

Threats

  • Clinical trial failures
  • Competition from larger pharmaceutical companies
  • Regulatory hurdles
  • Patent expirations
  • Economic downturn impacting R&D spending

Competitors and Market Share

competitor logo Key Competitors

  • LLY
  • BMY
  • JNJ

Competitive Landscape

Tyra Biosciences competes with larger pharmaceutical companies with established oncology portfolios. Its advantage lies in its focus on specific cancer-driving mutations and its potential to develop novel therapies that overcome drug resistance. TYRA's disadvantage is lack of established products/sales compared to larger Pharma.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical growth is measured by the progress of its drug candidates through preclinical and clinical development.

Future Projections: Future growth projections are based on analyst estimates of peak sales potential for its drug candidates if approved. These projections are highly speculative.

Recent Initiatives: Recent initiatives include advancing TYRA-300 in clinical trials, progressing TYRA-200 through IND-enabling studies, and expanding its pipeline of targeted therapies.

Summary

Tyra Biosciences is a clinical-stage precision oncology company with promising drug candidates targeting specific cancer mutations. The company has an experienced management team. Key risks include clinical trial failures, competition from established players, and high R&D spending. Successful clinical trial results and strategic partnerships are critical for its future growth.

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Sources and Disclaimers

Data Sources:

  • Company SEC Filings
  • Company Website
  • Analyst Reports
  • Industry Databases

Disclaimers:

The information provided is for informational purposes only and should not be considered investment advice. Investment decisions should be based on your own research and due diligence. Market share data for clinical-stage companies is limited and estimates.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Tyra Biosciences Inc

Exchange NASDAQ
Headquaters Carlsbad, CA, United States
IPO Launch date 2021-09-15
Co-Founder, President, CEO, Secretary, Treasurer & Director Dr. Todd Harris Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 60
Full time employees 60

Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SNÅP, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions. Its lead product candidate is TYRA-300, which is in clinical trials for the treatment of patients with metastatic urothelial carcinoma and other solid tumors. The company is also developing TYRA-300 for skeletal conditions, including achondroplasia, hypochondroplasia, thanatophoric dysplasia, and other FGFR3-driven genetic syndromes; TYRA-200, a candidate in clinical trial for bile duct and solid tumors; and TYRA-430 for the treatment of hepatocellular carcinoma. The company was incorporated in 2018 and is headquartered in Carlsbad, California.

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