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2Seventy Bio Inc (TSVT)TSVT
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Upturn Advisory Summary
09/18/2024: TSVT (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -15.13% | Upturn Advisory Performance 1 | Avg. Invested days: 31 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -15.13% | Avg. Invested days: 31 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 243.07M USD |
Price to earnings Ratio - | 1Y Target Price 10.75 |
Dividends yield (FY) - | Basic EPS (TTM) -3.06 |
Volume (30-day avg) 290640 | Beta 1.78 |
52 Weeks Range 1.53 - 6.40 | Updated Date 09/19/2024 |
Company Size Small-Cap Stock | Market Capitalization 243.07M USD | Price to earnings Ratio - | 1Y Target Price 10.75 |
Dividends yield (FY) - | Basic EPS (TTM) -3.06 | Volume (30-day avg) 290640 | Beta 1.78 |
52 Weeks Range 1.53 - 6.40 | Updated Date 09/19/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -227.01% |
Management Effectiveness
Return on Assets (TTM) -19.02% | Return on Equity (TTM) -51.89% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 292592220 | Price to Sales(TTM) 5.51 |
Enterprise Value to Revenue 6.63 | Enterprise Value to EBITDA -1.29 |
Shares Outstanding 51497900 | Shares Floating 49997278 |
Percent Insiders 4.07 | Percent Institutions 95.69 |
Trailing PE - | Forward PE - | Enterprise Value 292592220 | Price to Sales(TTM) 5.51 |
Enterprise Value to Revenue 6.63 | Enterprise Value to EBITDA -1.29 | Shares Outstanding 51497900 | Shares Floating 49997278 |
Percent Insiders 4.07 | Percent Institutions 95.69 |
Analyst Ratings
Rating 3.5 | Target Price 16.5 | Buy - |
Strong Buy 2 | Hold 3 | Sell 1 |
Strong Sell - |
Rating 3.5 | Target Price 16.5 | Buy - | Strong Buy 2 |
Hold 3 | Sell 1 | Strong Sell - |
AI Summarization
2Seventy Bio Inc.: A Comprehensive Overview
Company Profile:
Detailed History and Background:
2Seventy Bio Inc. is a clinical-stage biopharmaceutical company founded in 2018 and headquartered in Cambridge, Massachusetts. The company focuses on developing novel therapies for patients with severe and life-threatening diseases.
Core Business Areas:
2Seventy Bio's core business revolves around:
- Developing next-generation therapies: The company leverages its deep understanding of innate immunity and protein engineering to design highly targeted and effective treatments.
- Addressing unmet medical needs: 2Seventy Bio focuses on diseases with limited or no treatment options, aiming to improve the lives of patients facing significant health challenges.
- Building a robust pipeline: The company currently has a diverse portfolio of programs targeting various disease areas, including hematology, oncology, and inflammation.
Leadership Team and Corporate Structure:
2Seventy Bio boasts a seasoned leadership team with extensive experience in drug development and commercialization. Key members include:
- CEO and Co-founder: Dr. Thomas F. Bumol, PhD, a seasoned executive with over 25 years of experience in the biopharmaceutical industry.
- President and COO: Dr. George A. Donohue, MD, a physician-scientist with over 20 years of experience in research and development.
- Chief Medical Officer: Dr. Anne J. L. Hampson, MD, a renowned hematologist with extensive experience in clinical development.
The company operates with a Board of Directors composed of distinguished individuals with expertise in finance, science, and business.
Top Products and Market Share:
Currently, 2Seventy Bio has no marketed products as they are still in the clinical development stage. However, their pipeline includes several promising candidates:
- SBC-103: A novel Nanodecoy® targeting CCL2 for the treatment of hematologic malignancies and solid tumors. It is currently in Phase 1/2 clinical trials.
- SBC-105: A Nanodecoy® targeting CXCL12 for the treatment of hematologic malignancies and fibrosis. It is in the preclinical development stage.
- SBC-109: A Nanodecoy® targeting CCL21 for the treatment of autoimmune and inflammatory diseases. It is in the preclinical development stage.
While 2Seventy Bio does not have a market share yet, their innovative pipeline holds significant potential to disrupt the market in various therapeutic areas.
Total Addressable Market:
2Seventy Bio operates in several large and growing markets:
- Hematology: The global hematology market is estimated to reach USD 107.2 billion by 2028, growing at a CAGR of 9.3%.
- Oncology: The global oncology market is expected to reach USD 242.6 billion by 2028, with a CAGR of 10.2%.
- Inflammation: The global inflammatory disease market is projected to reach USD 34.4 billion by 2027, with a CAGR of 6.5%.
These significant market sizes highlight the vast opportunities for 2Seventy Bio's therapies.
Financial Performance:
As a clinical-stage company, 2Seventy Bio primarily focuses on research and development, resulting in no current revenue or profit. However, the company has raised significant capital through private placements and venture debt, demonstrating investor confidence in its pipeline's potential.
Dividends and Shareholder Returns:
2Seventy Bio does not currently pay dividends as it is a growth-stage company reinvesting its resources into R&D. Shareholder returns will depend on the success of their clinical trials and future commercialization efforts.
Growth Trajectory:
2Seventy Bio has experienced significant growth in recent years, driven by its promising pipeline and strategic partnerships. The company has expanded its team, advanced its lead programs into clinical trials, and secured substantial funding to support its development efforts.
Market Dynamics:
The biopharmaceutical industry is characterized by rapid innovation, intense competition, and stringent regulatory requirements. 2Seventy Bio is well-positioned within this dynamic environment with its differentiated technology platform and focus on unmet medical needs.
Competitors:
2Seventy Bio faces competition from established pharmaceutical companies and emerging biotech startups developing therapies in similar areas. Key competitors include:
- Macrogenics (MGNX)
- I-Mab (IMAB)
- Aclaris Therapeutics (ACRS)
- ADC Therapeutics (ADCT)
Potential Challenges and Opportunities:
Key Challenges:
- Clinical trial success: 2Seventy Bio's future is dependent on the successful outcome of its clinical trials, which involve inherent risks and uncertainties.
- Competition: The company faces intense competition from established players and innovative startups in the biopharmaceutical industry.
- Regulatory hurdles: Navigation of complex regulatory processes is crucial for 2Seventy Bio's eventual market entry.
Potential Opportunities:
- Large market potential: The markets 2Seventy Bio targets offer significant opportunities for growth and profitability.
- Promising pipeline: The company's unique pipeline holds the potential to address significant unmet medical needs and disrupt current treatment paradigms.
- Strategic partnerships: Collaborations with larger pharmaceutical companies could accelerate development and commercialization efforts.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About 2Seventy Bio Inc
Exchange | NASDAQ | Headquaters | Cambridge, MA, United States |
IPO Launch date | 2021-11-03 | CEO, President & Director | Mr. William D. Baird III, M.B.A. |
Sector | Healthcare | Website | https://www.2seventybio.com |
Industry | Biotechnology | Full time employees | 274 |
Headquaters | Cambridge, MA, United States | ||
CEO, President & Director | Mr. William D. Baird III, M.B.A. | ||
Website | https://www.2seventybio.com | ||
Website | https://www.2seventybio.com | ||
Full time employees | 274 |
2seventy bio, Inc., a cell and gene therapy company, focuses on the research, development, and commercialization of treatments for cancer in the United States. The company's products pipeline includes Abecma, a chimeric antigen receptor T-cell product candidates for the treatment of multiple myeloma. It has a collaboration arrangement with Bristol Myers Squibb Company. The company was incorporated in 2021 and is headquartered in Cambridge, Massachusetts.
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