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Turnstone Biologics Corp. Common Stock (TSBX)TSBX
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Upturn Advisory Summary
09/18/2024: TSBX (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -32.92% | Upturn Advisory Performance 1 | Avg. Invested days: 36 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -32.92% | Avg. Invested days: 36 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 15.06M USD |
Price to earnings Ratio - | 1Y Target Price 6.58 |
Dividends yield (FY) - | Basic EPS (TTM) -3.23 |
Volume (30-day avg) 443827 | Beta - |
52 Weeks Range 0.58 - 5.75 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 15.06M USD | Price to earnings Ratio - | 1Y Target Price 6.58 |
Dividends yield (FY) - | Basic EPS (TTM) -3.23 | Volume (30-day avg) 443827 | Beta - |
52 Weeks Range 0.58 - 5.75 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -66.1% | Return on Equity (TTM) -134.46% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -45130438 | Price to Sales(TTM) 2.13 |
Enterprise Value to Revenue - | Enterprise Value to EBITDA 0.8 |
Shares Outstanding 23128500 | Shares Floating 14093323 |
Percent Insiders 3.83 | Percent Institutions 65.7 |
Trailing PE - | Forward PE - | Enterprise Value -45130438 | Price to Sales(TTM) 2.13 |
Enterprise Value to Revenue - | Enterprise Value to EBITDA 0.8 | Shares Outstanding 23128500 | Shares Floating 14093323 |
Percent Insiders 3.83 | Percent Institutions 65.7 |
Analyst Ratings
Rating 4 | Target Price 17 | Buy 1 |
Strong Buy 1 | Hold 1 | Sell - |
Strong Sell - |
Rating 4 | Target Price 17 | Buy 1 | Strong Buy 1 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Turnstone Biologics Corp. Common Stock: A Comprehensive Overview
Company Profile:
Detailed History and Background:
Turnstone Biologics Corp. (TSBIO:NASDAQ) is a clinical-stage biopharmaceutical company focused on developing novel protein therapeutics for the treatment of severe and often rare hematologic disorders. Founded in 2015, the company draws upon its scientific expertise in protein engineering and deep understanding of the human immune system to develop innovative medicines.
TSBIO began its journey with preclinical development of therapies targeting the hepcidin pathway for the treatment of iron deficiency anemia associated with chronic kidney disease. Following a 2018 IPO, the company expanded its pipeline to include additional hematologic disorders such as beta-thalassemia and myelodysplastic syndromes. Today, TSBIO is actively advancing two lead product candidates towards clinical investigation:
- TSB-101: A novel hepcidin antagonist designed to treat iron deficiency anemia.
- TSB-102: A first-in-class erythropoiesis-stimulating protein therapeutic for beta-thalassemia.
Description of the Company's Core Business Areas:
TSBIO's core business areas can be outlined as:
- Discovery and development of novel protein therapies: Leveraging its expertise, TSBIO focuses on creating innovative medications for severe hematologic conditions.
- Clinical program advancement: Conducting clinical trials to evaluate the safety and efficacy of their lead product candidates in targeted patient populations.
- Strategic partnerships: Collaborating with researchers and academic institutions to accelerate the development of their pipeline.
Overview of the Company's Leadership Team and Corporate Structure:
TSBIO's leadership team boasts a wealth of experience in drug development and commercialization:
- J. Mark Stewart, Ph.D., Chief Executive Officer: Dr. Stewart brings over 20 years of experience in the pharmaceutical industry, with expertise in R&D leadership roles at companies like Genentech and OSI Pharmaceuticals.
- Scott D. Stromatt, M.D., Chief Medical Officer: Dr. Stromatt also holds significant experience in the field, having held leadership positions in clinical development at notable companies like Amgen and Gilead.
- Patrick J. Soon-Shiong, M.D., Chairman and Executive Founder: Dr. Soon-Shiong, a renowned physician-scientist and entrepreneur, founded NantWorks, the parent company of TSBIO, and carries extensive experience driving innovation in cancer research.
TSBIO operates under a centralized corporate structure, with key functions managed by the leadership team and supported by external partnerships for specialized services.
Top Products and Market Share:
Identification and Description of Top Products and Offerings:
Currently, TSBIO's top product candidates in development are:
- TSB-101: This hepcidin antagonist aims to treat iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). CKD-related IDA significantly impacts patients' clinical outcomes and quality of life. TSB-101 offers a potential alternative to existing iron replacement therapies, which pose limitations like administration inconvenience and side effects.
- TSB-102: This first-in-class erythropoiesis-stimulating protein (ESP) targets beta-thalassemia, a rare genetic blood disorder. TSB-102 functions uniquely by directly stimulating erythropoiesis, the process of red blood cell production, thus reducing the need for frequent blood transfusions that patients currently rely on.
Analysis of the Market Share of These Products in the Global and US Markets:
As TSBIO's products are still in development, they hold no market share currently. Both TSB-101 and TSB-102 have the potential to capture significant market positions within their respective target conditions. The global market for IDA treatment is estimated to reach USD 7.8 billion by 2030, while the beta-thalassemia treatment market could reach USD 1.9 billion by 2028.
Comparison of Product Performance and Market Reception against Competitors:
TSB-101 faces competition from existing iron replacement therapies like intravenous iron formulations. However, TSB-101 offers potential advantages in terms of convenience and efficacy. TSB-102 competes with ESPs like Aranesp and Procrit but aims to differentiate itself through its unique mechanism of action and potential for improved patient outcomes. Both products will need to demonstrate safety and efficacy in clinical trials to gain market acceptance.
Total Addressable Market:
TSBIO operates in the global market for hematologic disorder treatments, specifically focusing on IDA and beta-thalassemia. This market encompasses a large patient population, with estimates suggesting over 100 million with IDA globally and approximately 80,000 individuals with beta-thalassemia.
Financial Performance:
For the fiscal year concluding December 31, 2022, TSBIO reported a $106.9 million net loss. With no marketed products, the company currently generates no revenue. Its financial profile is primarily driven by research and development expenses related to clinical trials for its product candidates. As of December 3
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Turnstone Biologics Corp. Common Stock
Exchange | NASDAQ | Headquaters | La Jolla, CA, United States |
IPO Launch date | 2023-07-21 | President, CEO & Director | Dr. Sammy J. Farah M.B.A., Ph.D. |
Sector | Healthcare | Website | https://turnstonebio.com |
Industry | Biotechnology | Full time employees | 82 |
Headquaters | La Jolla, CA, United States | ||
President, CEO & Director | Dr. Sammy J. Farah M.B.A., Ph.D. | ||
Website | https://turnstonebio.com | ||
Website | https://turnstonebio.com | ||
Full time employees | 82 |
Turnstone Biologics Corp., a clinical stage biotechnology company, focuses on developing medicines to treat and cure patients with solid tumors. The company's lead product includes TIDAL-01 that is in Phase 1 clinical trials for the treatment of breast cancer, colorectal cancer, head and neck cancer and uveal melanoma, as well as an investigator sponsored trials to treat colorectal cancer, head and neck cancer, and cutaneous and non-cutaneous melanomas. It is also developing TIDAL-02, which is in preclinical development for the treatment of solid tumors. The company was founded in 2014 and is based in LA Jolla, California.
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