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TRML
Upturn stock ratingUpturn stock rating

Tourmaline Bio Inc. (TRML)

Upturn stock ratingUpturn stock rating
$14.24
Delayed price
Profit since last BUY-15.64%
upturn advisory
WEAK BUY
BUY since 9 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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Upturn Advisory Summary

04/01/2025: TRML (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Analysis of Past Performance

Type Stock
Historic Profit 43.75%
Avg. Invested days 34
Today’s Advisory WEAK BUY
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 3.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 428.51M USD
Price to earnings Ratio -
1Y Target Price 56.44
Price to earnings Ratio -
1Y Target Price 56.44
Volume (30-day avg) 322557
Beta -
52 Weeks Range 11.87 - 29.79
Updated Date 04/1/2025
52 Weeks Range 11.87 - 29.79
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.89

Earnings Date

Report Date 2025-03-17
When Before Market
Estimate -0.87
Actual -0.86

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -21.6%
Return on Equity (TTM) -28.99%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 131845812
Price to Sales(TTM) -
Enterprise Value 131845812
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -281.95
Shares Outstanding 25685400
Shares Floating 15577956
Shares Outstanding 25685400
Shares Floating 15577956
Percent Insiders 22.58
Percent Institutions 85.74

Analyst Ratings

Rating 4.62
Target Price 57.29
Buy 3
Strong Buy 5
Buy 3
Strong Buy 5
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Tourmaline Bio Inc.

stock logo

Company Overview

overview logo History and Background

Tourmaline Bio, Inc. is a late-stage clinical biopharmaceutical company focused on developing transformative medicines to benefit patients with debilitating diseases. Founded in 2022, the company is relatively new and rapidly advancing its lead asset, TOUR006, an anti-IL-6 antibody.

business area logo Core Business Areas

  • Drug Development: Focuses on the research and development of novel therapeutics, particularly TOUR006, for autoimmune and inflammatory diseases.

leadership logo Leadership and Structure

The company is led by a management team with experience in drug development and biotechnology. Specific details on the complete organizational structure are not publicly available.

Top Products and Market Share

overview logo Key Offerings

  • TOUR006: TOUR006 is Tourmaline Bio's lead product candidate, a fully human, high affinity anti-IL-6 antibody being developed for Thyroid Eye Disease (TED) and other autoimmune and inflammatory conditions. As a clinical stage product, there is no current market share or revenue. Competitors in the IL-6 pathway include Roche (Actemra) and Sanofi (Kevzara).

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is highly competitive and characterized by rapid technological advancements. The autoimmune and inflammatory disease market is substantial and growing, driven by unmet medical needs and aging populations.

Positioning

Tourmaline Bio aims to establish itself as a key player in the autoimmune and inflammatory disease market through its novel anti-IL-6 antibody, TOUR006. Its competitive advantage lies in the potential for improved efficacy and safety compared to existing IL-6 inhibitors.

Total Addressable Market (TAM)

The total addressable market for IL-6 inhibitors in autoimmune and inflammatory diseases is estimated to be billions of dollars annually. Tourmaline Bio is targeting specific indications like Thyroid Eye Disease (TED) and others, hoping to capture a significant portion of this market.

Upturn SWOT Analysis

Strengths

  • Novel therapeutic approach (TOUR006)
  • Experienced management team
  • Strong financial backing
  • Focus on high unmet medical needs

Weaknesses

  • Single product pipeline (TOUR006)
  • Clinical stage development risk
  • Limited commercial infrastructure

Opportunities

  • Expansion into new indications for TOUR006
  • Partnerships with larger pharmaceutical companies
  • Positive clinical trial results
  • Potential for breakthrough therapy designation

Threats

  • Clinical trial failures
  • Competition from established IL-6 inhibitors
  • Regulatory hurdles
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • RHHBY
  • SNY

Competitive Landscape

Tourmaline Bio faces competition from established pharmaceutical companies with approved IL-6 inhibitors. Its competitive advantage depends on demonstrating superior efficacy and safety with TOUR006.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Tourmaline Bio's historical growth is characterized by the rapid advancement of TOUR006 through clinical development.

Future Projections: Future growth is contingent on positive clinical trial results and successful commercialization of TOUR006.

Recent Initiatives: Recent initiatives include initiating and progressing clinical trials for TOUR006 in various indications.

Summary

Tourmaline Bio is a clinical-stage company with a promising lead candidate, TOUR006, targeting autoimmune and inflammatory diseases. Its success hinges on positive clinical trial outcomes and navigating a competitive landscape. The company's strengths lie in its novel therapeutic approach and experienced management. However, it faces risks associated with clinical development and competition from established players.

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Sources and Disclaimers

Data Sources:

  • Company website
  • SEC filings
  • Analyst reports
  • ClinicalTrials.gov

Disclaimers:

The information provided is for informational purposes only and should not be considered investment advice. Investment decisions should be based on thorough research and consultation with a financial professional.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Tourmaline Bio Inc.

Exchange NASDAQ
Headquaters New York, NY, United States
IPO Launch date 2021-05-07
Co-Founder, CEO & Director Dr. Sandeep C. Kulkarni M.D.
Sector Healthcare
Industry Biotechnology
Full time employees 74
Full time employees 74

Tourmaline Bio, Inc. operates as a clinical biotechnology company that develops medicines for patients with life-altering immune and inflammatory diseases. It develops TOUR006, a human anti-IL-6 monoclonal antibody that selectively binds to interleukin-6, a key proinflammatory cytokine involved in the pathogenesis of many autoimmune and inflammatory disorders. The company's development pipeline comprises medicines and therapies for the atherosclerotic cardiovascular disease (ASCVD) and thyroid eye disease (TED). The company was formerly known as Tourmaline Bio, LLC and changed its name to Tourmaline Bio, Inc. in September 2022. Tourmaline Bio, Inc. was founded in 2021 and is headquartered in New York, New York.

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