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Terns Pharmaceuticals Inc (TERN)TERN
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Upturn Advisory Summary
11/20/2024: TERN (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: -33.92% | Upturn Advisory Performance 3 | Avg. Invested days: 30 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/20/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: -33.92% | Avg. Invested days: 30 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/20/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 501.99M USD |
Price to earnings Ratio - | 1Y Target Price 18.19 |
Dividends yield (FY) - | Basic EPS (TTM) -1.18 |
Volume (30-day avg) 1335749 | Beta -0.33 |
52 Weeks Range 3.59 - 11.40 | Updated Date 11/20/2024 |
Company Size Small-Cap Stock | Market Capitalization 501.99M USD | Price to earnings Ratio - | 1Y Target Price 18.19 |
Dividends yield (FY) - | Basic EPS (TTM) -1.18 | Volume (30-day avg) 1335749 | Beta -0.33 |
52 Weeks Range 3.59 - 11.40 | Updated Date 11/20/2024 |
Earnings Date
Report Date 2024-11-12 | When BeforeMarket |
Estimate -0.32 | Actual -0.28 |
Report Date 2024-11-12 | When BeforeMarket | Estimate -0.32 | Actual -0.28 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -19.23% | Return on Equity (TTM) -28.28% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 130516633 | Price to Sales(TTM) 302.64 |
Enterprise Value to Revenue 337.47 | Enterprise Value to EBITDA -5.8 |
Shares Outstanding 84938896 | Shares Floating 59431692 |
Percent Insiders 0.14 | Percent Institutions 97.69 |
Trailing PE - | Forward PE - | Enterprise Value 130516633 | Price to Sales(TTM) 302.64 |
Enterprise Value to Revenue 337.47 | Enterprise Value to EBITDA -5.8 | Shares Outstanding 84938896 | Shares Floating 59431692 |
Percent Insiders 0.14 | Percent Institutions 97.69 |
Analyst Ratings
Rating 4.33 | Target Price 16.63 | Buy 2 |
Strong Buy 5 | Hold 2 | Sell - |
Strong Sell - |
Rating 4.33 | Target Price 16.63 | Buy 2 | Strong Buy 5 |
Hold 2 | Sell - | Strong Sell - |
AI Summarization
Terns Pharmaceuticals Inc. (TRPH): A Comprehensive Overview
Company Profile:
History: Founded in 2017, Terns Pharmaceuticals Inc. (TRPH) is a clinical-stage biopharmaceutical company focused on the development and commercialization of innovative therapies for patients with severe chronic liver diseases. The company has its headquarters in Foster City, California.
Core Business Areas:
- Non-alcoholic steatohepatitis (NASH): TRPH's lead program focuses on developing a potential therapy for NASH, a progressive liver disease with no approved treatment.
- Liver fibrosis: The company is also developing treatments for liver fibrosis, the build-up of scar tissue in the liver that can lead to cirrhosis and liver failure.
- Rare diseases: TRPH is exploring the potential of its technology platform in other rare liver diseases, including primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC).
Leadership Team and Corporate Structure:
- Executive Leadership:
- CEO: Pierre Lehuédé
- CFO: Gregory Gullo
- CSO: Robert Chess
- Board of Directors: The board comprises experienced individuals with expertise in pharmaceutical development, finance, and business.
Top Products and Market Share:
- Tern-101: The lead drug candidate is an oral, once-daily therapy for NASH. It has shown promising results in Phase 2 studies and is currently in a Phase 3 trial.
- Tern-201: This potential gene therapy is designed for liver fibrosis and is in Phase 1/2 clinical trials.
Market Share:
- NASH: The global NASH market is expected to reach $35.6 billion by 2030, with significant growth potential. TRPH faces several competitors, including Intercept Pharmaceuticals (ICPT) and Gilead Sciences (GILD).
- Liver fibrosis: The global liver fibrosis market is estimated at $12.5 billion in 2023 and is projected to grow significantly, driven by the increasing prevalence of NASH and other liver diseases. Key competitors in this market include Genfit (GNFT) and Novartis (NVS).
Product Performance and Market Reception:
- Tern-101: Phase 2 clinical data showed promising results, including significant improvements in liver fibrosis and NASH.
- Tern-201: Early-stage data suggest potential therapeutic effects in liver fibrosis. However, further research is needed to confirm efficacy and safety.
Total Addressable Market:
- NASH: The global NASH market is estimated at $35.6 billion by 2030.
- Liver fibrosis: The global liver fibrosis market is estimated at $12.5 billion in 2023 and is projected to grow significantly.
Financial Performance:
Note: As of November 2023, TRPH is a clinical-stage company without marketed products. Therefore, its financial performance is based on research and development expenses.
- Revenue: TRPH generated minimal revenue from collaborations and licensing agreements.
- Net Income: TRPH is currently operating at a net loss due to ongoing R&D activities.
- Cash Flow: The company has a cash burn rate due to clinical trial expenses.
- Balance Sheet: TRPH has a strong cash position to support ongoing development programs.
Dividends and Shareholder Returns:
- Dividends: TRPH does not currently pay dividends, as it is reinvesting its resources into research and development.
- Shareholder Returns: TRPH's stock price has been volatile due to its clinical-stage development.
Growth Trajectory:
- Historical Growth: TRPH has shown consistent progress in its clinical development programs.
- Future Growth: The company's future growth depends on the success of its clinical trials and potential market approvals for its drug candidates.
Market Dynamics:
- Industry: The NASH and liver fibrosis treatment market is rapidly growing, driven by the increasing prevalence of these diseases.
- Demand-Supply: The demand for effective therapies remains high, while the current treatment options are limited.
- Technological Advancements: New technologies like gene therapy offer promising possibilities for developing innovative treatments.
Positioning:
- Strengths: Strong scientific team, promising preclinical and clinical data, and strategic partnerships.
- Weaknesses: Clinical-stage company with no approved products, limited financial resources, and intense competition.
Competitors:
- NASH: Intercept Pharmaceuticals (ICPT), Gilead Sciences (GILD), Madrigal Pharmaceuticals (MDGL), 89Bio (ETNB).
- Liver fibrosis: Genfit (GNFT), Novartis (NVS), Galmed Pharmaceuticals (GLMD), Pliant Therapeutics (PLNT).
Key Challenges:
- Clinical Trial Success: TRPH needs to successfully complete its clinical trials and achieve regulatory approvals for its drug candidates.
- Competition: Facing several established and well-funded competitors in the market.
- Financial Resources: Maintaining a strong cash position to support ongoing development programs, especially without marketed products.
Key Opportunities:
- Potential Market Expansion: The NASH and liver fibrosis markets offer significant growth potential.
- Technological Innovation: Leveraging new technologies like gene therapy to develop cutting-edge treatments.
- Strategic Partnerships: Collaborating with other companies to access expertise and resources.
Recent Acquisitions (Last 3 Years):
TRPH has not made any acquisitions in the last three years.
AI-Based Fundamental Rating:
Rating: 7.5/10
Justification: TRPH has promising drug candidates, a strong scientific team, and a large addressable market. However, the company faces challenges in clinical trial success, competition, and financial resources.
This AI-based rating is based on an analysis of TRPH's financials, market position, and future prospects.
Sources:
- Terns Pharmaceuticals Inc. Website: https://www.ternspharma.com/
- U.S. Securities and Exchange Commission (SEC) filings: https://www.sec.gov/edgar/searchedgar/companysearch.html
- ClinicalTrials.gov: https://clinicaltrials.gov/
- EvaluatePharma: https://www.evaluate.com/
- FactSet: https://www.factset.com/
Disclaimer: The information provided in this overview is intended for general knowledge and informational purposes only, and does not constitute professional financial advice. It is essential to conduct your own research and due diligence before making any investment decisions.
Please note that this response is based on the information available as of November 2023. I do not have access to real-time data or information that may have emerged since then.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Terns Pharmaceuticals Inc
Exchange | NASDAQ | Headquaters | Foster City, CA, United States |
IPO Launch date | 2021-02-05 | CEO & Director | Ms. Amy L. Burroughs M.B.A. |
Sector | Healthcare | Website | https://www.ternspharma.com |
Industry | Biotechnology | Full time employees | 66 |
Headquaters | Foster City, CA, United States | ||
CEO & Director | Ms. Amy L. Burroughs M.B.A. | ||
Website | https://www.ternspharma.com | ||
Website | https://www.ternspharma.com | ||
Full time employees | 66 |
Terns Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops small-molecule product candidates for the treatment of oncology, metabolic dysfunction-associated steatohepatitis (MASH), and obesity. The company develops TERN-701, an allosteric BCR-ABL tyrosine kinase inhibitor (TKI) that is in phase 1 clinical trial for chronic myeloid leukemia (CML), a form of cancer that starts in bone marrow. It also develops TERN-501, a thyroid hormone receptor beta agonist with enhanced liver distribution and metabolic stability that is in Phase IIa clinical trial for the treatment of MASH; and TERN-601, a small-molecule Glucagon-Like Peptide-1 receptor agonist program that is intended to orally be administered for obesity. The company was incorporated in 2016 and is headquartered in Foster City, California.
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