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Terns Pharmaceuticals Inc (TERN)TERN

Upturn stock ratingUpturn stock rating
Terns Pharmaceuticals Inc
$5.6
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

11/20/2024: TERN (1-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: -33.92%
Upturn Advisory Performance Upturn Advisory Performance3
Avg. Invested days: 30
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/20/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: -33.92%
Avg. Invested days: 30
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/20/2024
Upturn Advisory Performance Upturn Advisory Performance3

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 501.99M USD
Price to earnings Ratio -
1Y Target Price 18.19
Dividends yield (FY) -
Basic EPS (TTM) -1.18
Volume (30-day avg) 1335749
Beta -0.33
52 Weeks Range 3.59 - 11.40
Updated Date 11/20/2024
Company Size Small-Cap Stock
Market Capitalization 501.99M USD
Price to earnings Ratio -
1Y Target Price 18.19
Dividends yield (FY) -
Basic EPS (TTM) -1.18
Volume (30-day avg) 1335749
Beta -0.33
52 Weeks Range 3.59 - 11.40
Updated Date 11/20/2024

Earnings Date

Report Date 2024-11-12
When BeforeMarket
Estimate -0.32
Actual -0.28
Report Date 2024-11-12
When BeforeMarket
Estimate -0.32
Actual -0.28

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -19.23%
Return on Equity (TTM) -28.28%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 130516633
Price to Sales(TTM) 302.64
Enterprise Value to Revenue 337.47
Enterprise Value to EBITDA -5.8
Shares Outstanding 84938896
Shares Floating 59431692
Percent Insiders 0.14
Percent Institutions 97.69
Trailing PE -
Forward PE -
Enterprise Value 130516633
Price to Sales(TTM) 302.64
Enterprise Value to Revenue 337.47
Enterprise Value to EBITDA -5.8
Shares Outstanding 84938896
Shares Floating 59431692
Percent Insiders 0.14
Percent Institutions 97.69

Analyst Ratings

Rating 4.33
Target Price 16.63
Buy 2
Strong Buy 5
Hold 2
Sell -
Strong Sell -
Rating 4.33
Target Price 16.63
Buy 2
Strong Buy 5
Hold 2
Sell -
Strong Sell -

AI Summarization

Terns Pharmaceuticals Inc. (TRPH): A Comprehensive Overview

Company Profile:

History: Founded in 2017, Terns Pharmaceuticals Inc. (TRPH) is a clinical-stage biopharmaceutical company focused on the development and commercialization of innovative therapies for patients with severe chronic liver diseases. The company has its headquarters in Foster City, California.

Core Business Areas:

  • Non-alcoholic steatohepatitis (NASH): TRPH's lead program focuses on developing a potential therapy for NASH, a progressive liver disease with no approved treatment.
  • Liver fibrosis: The company is also developing treatments for liver fibrosis, the build-up of scar tissue in the liver that can lead to cirrhosis and liver failure.
  • Rare diseases: TRPH is exploring the potential of its technology platform in other rare liver diseases, including primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC).

Leadership Team and Corporate Structure:

  • Executive Leadership:
    • CEO: Pierre Lehuédé
    • CFO: Gregory Gullo
    • CSO: Robert Chess
  • Board of Directors: The board comprises experienced individuals with expertise in pharmaceutical development, finance, and business.

Top Products and Market Share:

  • Tern-101: The lead drug candidate is an oral, once-daily therapy for NASH. It has shown promising results in Phase 2 studies and is currently in a Phase 3 trial.
  • Tern-201: This potential gene therapy is designed for liver fibrosis and is in Phase 1/2 clinical trials.

Market Share:

  • NASH: The global NASH market is expected to reach $35.6 billion by 2030, with significant growth potential. TRPH faces several competitors, including Intercept Pharmaceuticals (ICPT) and Gilead Sciences (GILD).
  • Liver fibrosis: The global liver fibrosis market is estimated at $12.5 billion in 2023 and is projected to grow significantly, driven by the increasing prevalence of NASH and other liver diseases. Key competitors in this market include Genfit (GNFT) and Novartis (NVS).

Product Performance and Market Reception:

  • Tern-101: Phase 2 clinical data showed promising results, including significant improvements in liver fibrosis and NASH.
  • Tern-201: Early-stage data suggest potential therapeutic effects in liver fibrosis. However, further research is needed to confirm efficacy and safety.

Total Addressable Market:

  • NASH: The global NASH market is estimated at $35.6 billion by 2030.
  • Liver fibrosis: The global liver fibrosis market is estimated at $12.5 billion in 2023 and is projected to grow significantly.

Financial Performance:

Note: As of November 2023, TRPH is a clinical-stage company without marketed products. Therefore, its financial performance is based on research and development expenses.

  • Revenue: TRPH generated minimal revenue from collaborations and licensing agreements.
  • Net Income: TRPH is currently operating at a net loss due to ongoing R&D activities.
  • Cash Flow: The company has a cash burn rate due to clinical trial expenses.
  • Balance Sheet: TRPH has a strong cash position to support ongoing development programs.

Dividends and Shareholder Returns:

  • Dividends: TRPH does not currently pay dividends, as it is reinvesting its resources into research and development.
  • Shareholder Returns: TRPH's stock price has been volatile due to its clinical-stage development.

Growth Trajectory:

  • Historical Growth: TRPH has shown consistent progress in its clinical development programs.
  • Future Growth: The company's future growth depends on the success of its clinical trials and potential market approvals for its drug candidates.

Market Dynamics:

  • Industry: The NASH and liver fibrosis treatment market is rapidly growing, driven by the increasing prevalence of these diseases.
  • Demand-Supply: The demand for effective therapies remains high, while the current treatment options are limited.
  • Technological Advancements: New technologies like gene therapy offer promising possibilities for developing innovative treatments.

Positioning:

  • Strengths: Strong scientific team, promising preclinical and clinical data, and strategic partnerships.
  • Weaknesses: Clinical-stage company with no approved products, limited financial resources, and intense competition.

Competitors:

  • NASH: Intercept Pharmaceuticals (ICPT), Gilead Sciences (GILD), Madrigal Pharmaceuticals (MDGL), 89Bio (ETNB).
  • Liver fibrosis: Genfit (GNFT), Novartis (NVS), Galmed Pharmaceuticals (GLMD), Pliant Therapeutics (PLNT).

Key Challenges:

  • Clinical Trial Success: TRPH needs to successfully complete its clinical trials and achieve regulatory approvals for its drug candidates.
  • Competition: Facing several established and well-funded competitors in the market.
  • Financial Resources: Maintaining a strong cash position to support ongoing development programs, especially without marketed products.

Key Opportunities:

  • Potential Market Expansion: The NASH and liver fibrosis markets offer significant growth potential.
  • Technological Innovation: Leveraging new technologies like gene therapy to develop cutting-edge treatments.
  • Strategic Partnerships: Collaborating with other companies to access expertise and resources.

Recent Acquisitions (Last 3 Years):

TRPH has not made any acquisitions in the last three years.

AI-Based Fundamental Rating:

Rating: 7.5/10

Justification: TRPH has promising drug candidates, a strong scientific team, and a large addressable market. However, the company faces challenges in clinical trial success, competition, and financial resources.

This AI-based rating is based on an analysis of TRPH's financials, market position, and future prospects.

Sources:

Disclaimer: The information provided in this overview is intended for general knowledge and informational purposes only, and does not constitute professional financial advice. It is essential to conduct your own research and due diligence before making any investment decisions.


Please note that this response is based on the information available as of November 2023. I do not have access to real-time data or information that may have emerged since then.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Terns Pharmaceuticals Inc

Exchange NASDAQ Headquaters Foster City, CA, United States
IPO Launch date 2021-02-05 CEO & Director Ms. Amy L. Burroughs M.B.A.
Sector Healthcare Website https://www.ternspharma.com
Industry Biotechnology Full time employees 66
Headquaters Foster City, CA, United States
CEO & Director Ms. Amy L. Burroughs M.B.A.
Website https://www.ternspharma.com
Website https://www.ternspharma.com
Full time employees 66

Terns Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops small-molecule product candidates for the treatment of oncology, metabolic dysfunction-associated steatohepatitis (MASH), and obesity. The company develops TERN-701, an allosteric BCR-ABL tyrosine kinase inhibitor (TKI) that is in phase 1 clinical trial for chronic myeloid leukemia (CML), a form of cancer that starts in bone marrow. It also develops TERN-501, a thyroid hormone receptor beta agonist with enhanced liver distribution and metabolic stability that is in Phase IIa clinical trial for the treatment of MASH; and TERN-601, a small-molecule Glucagon-Like Peptide-1 receptor agonist program that is intended to orally be administered for obesity. The company was incorporated in 2016 and is headquartered in Foster City, California.

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