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STRO logo STRO
Upturn stock ratingUpturn stock rating
STRO logo

Sutro Biopharma (STRO)

Upturn stock ratingUpturn stock rating
$0.6
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

04/01/2025: STRO (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -70%
Avg. Invested days 27
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 49.87M USD
Price to earnings Ratio -
1Y Target Price 3.43
Price to earnings Ratio -
1Y Target Price 3.43
Volume (30-day avg) 1756223
Beta 1.22
52 Weeks Range 0.58 - 5.28
Updated Date 04/1/2025
52 Weeks Range 0.58 - 5.28
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -2.96

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date 2025-03-24
When Before Market
Estimate -0.955
Actual -0.6332

Profitability

Profit Margin -
Operating Margin (TTM) -440.66%

Management Effectiveness

Return on Assets (TTM) -34.74%
Return on Equity (TTM) -234.19%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -243869536
Price to Sales(TTM) 1
Enterprise Value -243869536
Price to Sales(TTM) 1
Enterprise Value to Revenue 0.36
Enterprise Value to EBITDA 0.41
Shares Outstanding 83775296
Shares Floating 75352564
Shares Outstanding 83775296
Shares Floating 75352564
Percent Insiders 4.1
Percent Institutions 73.94

Analyst Ratings

Rating 4.55
Target Price 11.5
Buy 3
Strong Buy 7
Buy 3
Strong Buy 7
Hold 1
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Sutro Biopharma

stock logo

Company Overview

overview logo History and Background

Sutro Biopharma, founded in 2003, is a clinical-stage drug discovery, development and manufacturing company. It focuses on oncology and autoimmune disorders using its cell-free protein synthesis platform, XpressCFu00ae, and site-specific conjugation, XpressCFu00ae+.

business area logo Core Business Areas

  • Drug Discovery and Development: Sutro Biopharma focuses on discovering and developing antibody-drug conjugates (ADCs) and bispecific antibodies for cancer therapy.
  • Manufacturing: The company also engages in the manufacturing of clinical trial material and commercial products through partnerships.
  • Platform Technology: Sutro develops and uses its XpressCFu00ae and XpressCFu00ae+ platforms for improved antibody and ADC designs.

leadership logo Leadership and Structure

The leadership team includes Bill Newell (CEO), Arturo Molina (CMO), and Jane Chung (CFO). The company is structured around research and development, clinical operations, and manufacturing.

Top Products and Market Share

overview logo Key Offerings

  • STRO-002: An antibody-drug conjugate (ADC) targeting folate receptor alpha (FolRu03b1). It is being evaluated in clinical trials for ovarian cancer and endometrial cancer. Revenue from this product is currently negligible as it is still in clinical trials. Competitors include ImmunoGen (ELAHERE) and others developing FolRu03b1-targeted therapies.
  • STRO-003: An antibody-drug conjugate (ADC) targeting ROR1. Currently in phase 1 clinical trial for hematological malignancies and solid tumors. Revenue from this product is currently negligible as it is still in clinical trials. Competitors include NBE-Therapeutics and others developing ROR1-targeted therapies.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is characterized by intense competition, rapid technological advancements, and stringent regulatory requirements. The ADC market is growing significantly.

Positioning

Sutro Biopharma is positioned as an innovative company with a proprietary technology platform for ADC development. It holds a competitive advantage in the creation and manufacturing of unique ADCs.

Total Addressable Market (TAM)

The total addressable market for ADCs is expected to reach billions of dollars. Sutro Biopharma aims to capture a significant share of this market by developing innovative ADC therapies.

Upturn SWOT Analysis

Strengths

  • Proprietary XpressCFu00ae and XpressCFu00ae+ technology platforms
  • Strong pipeline of ADC and bispecific antibody candidates
  • Manufacturing capabilities
  • Strategic partnerships with major pharmaceutical companies

Weaknesses

  • Reliance on clinical trial success
  • Limited revenue stream compared to larger pharmaceutical companies
  • High research and development expenses
  • Dependence on partnerships for funding

Opportunities

  • Potential for breakthrough therapies in oncology and autoimmune diseases
  • Expansion of partnerships with pharmaceutical companies
  • Advancement of clinical programs to regulatory approval
  • Application of technology platform to new therapeutic areas

Threats

  • Clinical trial failures
  • Competition from larger pharmaceutical companies with greater resources
  • Regulatory hurdles
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • IMGN
  • MRNA
  • BGEN
  • MYOV
  • ALNY
  • ARWR
  • AVXL
  • BLUE
  • CRSP
  • EDIT
  • NTLA
  • INMD

Competitive Landscape

Sutro Biopharma has a focused approach with ADC technology, distinguishing it from larger, diversified pharmaceutical companies. However, these larger companies have substantially more resources.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical growth is tied to clinical milestones and partnerships, resulting in fluctuations.

Future Projections: Future growth projections are dependent on the success of clinical trials and regulatory approvals.

Recent Initiatives: Recent initiatives include advancing STRO-002 and STRO-003 clinical trials, securing partnerships, and expanding the pipeline.

Summary

Sutro Biopharma is a clinical-stage company with a promising ADC technology platform and a diverse pipeline. Success is dependent on clinical trial outcomes and regulatory approvals. The company's partnerships provide financial support, but it faces competition from larger pharmaceutical companies. Sutro needs to successfully navigate clinical trials and regulatory approval process while seeking to expand its strategic partnerships.

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Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Analyst Reports
  • ClinicalTrials.gov

Disclaimers:

This analysis is based on publicly available information and is not financial advice. Market share data is estimated.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Sutro Biopharma

Exchange NASDAQ
Headquaters South San Francisco, CA, United States
IPO Launch date 2018-09-27
CEO & Director Ms. Jane Chung R.Ph.
Sector Healthcare
Industry Biotechnology
Full time employees 310
Full time employees 310

Sutro Biopharma, Inc. operates as a oncology company. The company develops site-specific and novel-format antibody drug conjugates (ADCs) that enables its proprietary integrated cell-free protein synthesis platform, XpressCF; and site-specific conjugation platform, XpressCF+. Its lead product candidate includes STRO-004, a tissue factor (TF) targeting ADC for the treatment of TF-expressing solid tumors, including cervical, lung, and breast cancer. The company also develops VAX-24 and Vax-31 pneumococcal conjugate vaccine candidates that is in Phase II/III clinical trials for the treatment of invasive pneumococcal disease; and STRO-003, an ADC directed against an anti-receptor tyrosine kinase-like orphan receptor 1 (ROR1) for the treatment of solid tumors, such as triple negative breast cancer, non-small cell lung cancer, and ovarian cancer, as well as hematological cancers. Sutro Biopharma, Inc. has collaboration and license agreements with Vaxcyte to discover and develop vaccine candidates for the treatment or prophylaxis of infectious diseases; Tasly Biopharmaceuticals Co., Ltd. to develop and commercialize STRO-002 in Greater China; Ipsen to develop and commercialize STRO-003, an ADC targeting ROR1; and Astellas Pharma Inc. to develop immunostimulatory ADC. The company was formerly known as Fundamental Applied Biology, Inc. Sutro Biopharma, Inc. was incorporated in 2003 and is headquartered in South San Francisco, California.

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