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SRZN
Upturn stock ratingUpturn stock rating

Surrozen Inc (SRZN)

Upturn stock ratingUpturn stock rating
$11.12
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

04/01/2025: SRZN (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Analysis of Past Performance

Type Stock
Historic Profit -81.82%
Avg. Invested days 23
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 37.89M USD
Price to earnings Ratio -
1Y Target Price 38.5
Price to earnings Ratio -
1Y Target Price 38.5
Volume (30-day avg) 12202
Beta 0.74
52 Weeks Range 6.00 - 18.17
Updated Date 04/1/2025
52 Weeks Range 6.00 - 18.17
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -18.1

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) 12.32%

Management Effectiveness

Return on Assets (TTM) -32.65%
Return on Equity (TTM) -173.59%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 8736849
Price to Sales(TTM) 3.79
Enterprise Value 8736849
Price to Sales(TTM) 3.79
Enterprise Value to Revenue 0.87
Enterprise Value to EBITDA 0.71
Shares Outstanding 3249800
Shares Floating 219491
Shares Outstanding 3249800
Shares Floating 219491
Percent Insiders 1.67
Percent Institutions 83.56

Analyst Ratings

Rating 5
Target Price 45
Buy -
Strong Buy 1
Buy -
Strong Buy 1
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Surrozen Inc

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Company Overview

History and Background

Surrozen, Inc. was founded in 2016 and is a biotechnology company that discovers and develops antibody-based therapeutics to selectively modulate Wnt signaling for tissue repair and regeneration. It went public via SPAC merger in 2021. The company has focused on developing therapies for liver and intestinal diseases.

Core Business Areas

  • Liver Disease Therapeutics: Focuses on developing antibody therapeutics that target Wnt signaling to regenerate and repair damaged liver tissue in diseases like severe alcohol-associated hepatitis (sAH).
  • Intestinal Disease Therapeutics: Develops therapeutics aimed at intestinal regeneration and repair, targeting conditions like inflammatory bowel disease (IBD).
  • Discovery and Research: Continues to research and identify novel targets and develop platform technologies to further advance tissue regeneration.

Leadership and Structure

Surrozen has a board of directors and an executive leadership team responsible for strategic direction and operational execution. The CEO leads the management team, overseeing research, development, and business operations.

Top Products and Market Share

Key Offerings

  • SZN-1326 (Liver): An antibody targeting FZD5 for liver regeneration. Currently in clinical development for severe alcohol-associated hepatitis (sAH). Market share is not yet applicable as it is still in clinical trials. Competitors include companies developing other therapies for sAH, such as Gilead Sciences and Genfit, although these don't necessarily target the same Wnt pathway.
  • SZN-043 (Intestine): An antibody targeting R-spondin 3 for intestinal regeneration. Preclinical development focuses on inflammatory bowel disease (IBD). Market share is not applicable as it is still preclinical. Competitors developing IBD therapies include AbbVie (Humira, Rinvoq), Johnson & Johnson (Stelara), and Takeda (Entyvio).

Market Dynamics

Industry Overview

The biotechnology industry is characterized by high R&D spending, long development timelines, and regulatory scrutiny. Regenerative medicine, particularly targeting Wnt signaling, is an area of growing interest.

Positioning

Surrozen is positioned as a company focused on Wnt signaling modulation for tissue regeneration, differentiating itself through its specific antibody-based approach. Its competitive advantage lies in its expertise in Wnt pathway biology and its proprietary antibody technology.

Total Addressable Market (TAM)

The combined TAM for liver diseases and IBD is significant, estimated to be in the tens of billions of dollars. Surrozen aims to capture a portion of this market by addressing unmet needs in regenerative therapies for these conditions. The specific TAM will depend on the success of their clinical trials and regulatory approvals.

Upturn SWOT Analysis

Strengths

  • Proprietary antibody technology targeting Wnt signaling
  • Expertise in tissue regeneration and Wnt pathway biology
  • Potential to address unmet needs in liver and intestinal diseases

Weaknesses

  • Limited cash runway
  • Dependence on successful clinical trial outcomes
  • Early-stage development pipeline

Opportunities

  • Partnerships with larger pharmaceutical companies
  • Expansion of pipeline into new disease areas
  • Positive clinical trial data leading to increased investor confidence

Threats

  • Clinical trial failures
  • Competition from other biotechnology and pharmaceutical companies
  • Regulatory hurdles and delays

Competitors and Market Share

Key Competitors

  • GILD
  • ABBV
  • JNJ
  • TAK

Competitive Landscape

Surrozen differentiates itself through its Wnt-signaling-targeted approach. It competes with companies developing other therapies for liver and intestinal diseases but has the potential to offer a regenerative solution.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical growth is limited as the company is pre-revenue. Growth is measured by the progress of its pipeline and preclinical assets to clinical studies.

Future Projections: Future growth depends on the success of clinical trials for SZN-1326 and SZN-043. Analyst projections are based on estimates of potential market share and pricing if these therapies are approved.

Recent Initiatives: Recent initiatives include advancing SZN-1326 into clinical trials, ongoing preclinical development of SZN-043, and exploring potential partnerships.

Summary

Surrozen is an early-stage biotech company focused on innovative regenerative therapies. Its technology targeting the Wnt pathway for liver and intestinal diseases holds significant promise. However, the company faces typical biotech challenges, including cash constraints and clinical trial risks. Positive trial data and strategic partnerships are vital for Surrozen's success.

Similar Companies

  • GILD
  • ABBV
  • JNJ
  • TAK

Sources and Disclaimers

Data Sources:

  • Surrozen Inc. SEC Filings
  • Company Website
  • Analyst Reports
  • Industry Publications

Disclaimers:

This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be based on thorough research and consultation with a qualified financial advisor. Market share data is estimated.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Surrozen Inc

Exchange NASDAQ
Headquaters South San Francisco, CA, United States
IPO Launch date 2021-01-11
CEO, President & Director Mr. Craig C. Parker M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 42
Full time employees 42

Surrozen, Inc., a clinical stage biotechnology company, discovers and develops drug candidates to selectively modulate the Wnt pathway for tissue repair. The company is developing antibody-based therapeutics which targets various disease areas, including diseases of the intestine, liver, retina, cornea, lung, kidney, cochlea, skin, pancreas, and central nervous system. Its products in pipeline include SZN-043, a hepatocyte-specific R-spondin mimetic bispecific fusion protein, which is in Phase 1b clinical trial for the treatment of severe liver diseases, including alcohol-associated hepatitis. The company develops SZN-413, a Fzd4 targeted bi-specific antibody for the treatment of retinal vascular associated diseases. Surrozen, Inc. has collaboration and license agreement with Boehringer Ingelheim International GmbH to research, develop, and commercialize Fzd4 bi-specific antibodies. Surrozen, Inc. is based in South San Francisco, California.

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