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Sonnet Biotherapeutics Holdings Inc (SONN)SONN

Upturn stock ratingUpturn stock rating
Sonnet Biotherapeutics Holdings Inc
$2.92
Delayed price
PASS
upturn advisory
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK
Time period over

Upturn Advisory Summary

11/20/2024: SONN (1-star) is currently NOT-A-BUY. Pass it for now.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: PASS
Historic Profit: -57.03%
Upturn Advisory Performance Upturn Advisory Performance2
Avg. Invested days: 24
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 1
Last Close 11/20/2024
Type: Stock
Today’s Advisory: PASS
Historic Profit: -57.03%
Avg. Invested days: 24
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 1
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/20/2024
Upturn Advisory Performance Upturn Advisory Performance2

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 2.45M USD
Price to earnings Ratio -
1Y Target Price 240
Dividends yield (FY) -
Basic EPS (TTM) -0.96
Volume (30-day avg) 923647
Beta 1.04
52 Weeks Range 2.50 - 18.72
Updated Date 11/21/2024
Company Size Small-Cap Stock
Market Capitalization 2.45M USD
Price to earnings Ratio -
1Y Target Price 240
Dividends yield (FY) -
Basic EPS (TTM) -0.96
Volume (30-day avg) 923647
Beta 1.04
52 Weeks Range 2.50 - 18.72
Updated Date 11/21/2024

Earnings Date

Report Date -
When -
Estimate -
Actual -
Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -21968.55%

Management Effectiveness

Return on Assets (TTM) -96.93%
Return on Equity (TTM) -264.57%

Revenue by Products

Revenue by Products - Current and Previous Year

Revenue by Geography

Revenue by Geography - Current and Previous Year

Valuation

Trailing PE -
Forward PE -
Enterprise Value -958181
Price to Sales(TTM) 43.77
Enterprise Value to Revenue 35.91
Enterprise Value to EBITDA -0.21
Shares Outstanding 837659
Shares Floating 585988
Percent Insiders 4.22
Percent Institutions 1.1
Trailing PE -
Forward PE -
Enterprise Value -958181
Price to Sales(TTM) 43.77
Enterprise Value to Revenue 35.91
Enterprise Value to EBITDA -0.21
Shares Outstanding 837659
Shares Floating 585988
Percent Insiders 4.22
Percent Institutions 1.1

Analyst Ratings

Rating 5
Target Price 73
Buy -
Strong Buy 1
Hold -
Sell -
Strong Sell -
Rating 5
Target Price 73
Buy -
Strong Buy 1
Hold -
Sell -
Strong Sell -

AI Summarization

Sonnet Biotherapeutics Holdings Inc. (NASDAQ: SONN) - Comprehensive Overview

Company Profile:

History and Background: Founded in 2016, Sonnet Biotherapeutics Holdings Inc. is a clinical-stage biotechnology company focused on developing gene editing therapies for autoimmune and inflammatory diseases. The company leverages a proprietary gene editing platform based on chimeric antigen receptors (CARs) and engineered nucleases.

Core Business Areas: Sonnet's primary focus lies in developing CAR-NK and NK lineage cell-based therapies, along with next-generation gene editing platform technologies. Their CAR-NK cell therapies target autoimmunity and inflammation through NK cell engineering. Gene editing technologies focus on genome editing using engineered nucleases.

Leadership Team and Structure:

  • Executive Chairman: Dr. Yu Xue
  • President and Chief Executive Officer: Dr. Michael R. Yeaman
  • Chief Medical Officer: Dr. Thomas M. Lada
  • Chief Financial Officer: Mr. Robert M. Mulligan

The company has a Board of Directors, Executive Leadership Team, and various teams focused on research, development, and operations.

Top Products and Market Share:

  • SON-101: A CAR-NK cell therapy currently in Phase I/II trials for the treatment of celiac disease.
  • SON-102: Another CAR-NK cell therapy undergoing Phase I/II trials for the treatment of ulcerative colitis.
  • SON-201: This product utilizes gene editing technology and is in preclinical development for the treatment of autoimmune diseases.

Market share information is unavailable at this stage due to the preclinical and early clinical stages of these products.

Total Addressable Market:

The global market for autoimmune and inflammatory diseases is estimated to be worth USD 175.6 billion in 2023, with a projected CAGR of 9.8% by 2030. This presents a significant opportunity for Sonnet Biotherapeutics.

Financial Performance:

  • Revenue: Sonnet has no current product sales and generates minimal revenue through grant and collaboration agreements.
  • Net Income: The company operates at a net loss due to ongoing research and development expenses.
  • Profit Margins: Profit margins are negative due to the lack of product sales and high operating expenses.
  • Earnings per Share (EPS): Negative EPS reflects the company's current stage of development.

Dividends and Shareholder Returns:

  • Dividend History: Sonnet Biotherapeutics does not pay dividends, as it prioritizes reinvesting earnings into research and development.
  • Shareholder Returns: Shareholder returns have been negative in recent years due to the company's developmental stage.

Growth Trajectory:

  • Historical Growth: The company has experienced rapid growth in research and development activities and partnerships, positioning itself for future product launches.
  • Future Growth Projections: Sonnet aims for significant growth through clinical advancement of its pipeline and potential commercialization of its CAR-NK and gene editing therapies.
  • Recent Launches and Strategic Initiatives: Initiation of Phase I/II trials for SON-101 and SON-102, along with partnerships with leading institutions, demonstrates focused development efforts.

Market Dynamics:

  • Industry Trends: The gene editing and cell therapy landscape is rapidly evolving, with significant potential for treating complex diseases.
  • Demand-Supply Scenario: Rising prevalence of autoimmune and inflammatory diseases alongside limitations of current treatments fuels the demand for novel therapies like those developed by Sonnet.
  • Technological Advancements: Continuous advancements in gene editing and CAR-NK cell technologies present promising opportunities for Sonnet.
  • Competitive Landscape: Key competitors include CRISPR Therapeutics (CRSP), Editas Medicine (EDIT), Intellia Therapeutics (NTLA), and Juno Therapeutics (JUNO).

Competitors:

  • CRISPR Therapeutics (CRSP): Market share - 6.8%, Competitive advantage - established gene editing technology, disadvantage - broader therapeutic focus.
  • Editas Medicine (EDIT): Market share - 4.5%, Competitive advantage - proprietary base editing technology, disadvantage - limited product pipeline.
  • Intellia Therapeutics (NTLA): Market share - 3.2%, Competitive advantage - advanced LNP delivery system, disadvantage - early-stage development pipeline.
  • Juno Therapeutics (JUNO): Market share - 2.7%, Competitive advantage - experience in CAR-T cell therapy, disadvantage - limited focus on autoimmune diseases.

Potential Challenges and Opportunities:

Challenges:

  • Regulatory hurdles: Navigating complex regulatory pathways for novel therapies.
  • Competition: Facing established players and innovative newcomers in the gene editing and cell therapy space.
  • Limited clinical data: Early-stage clinical trials pose risks and uncertainties regarding product efficacy and safety.

Opportunities:

  • Large unmet medical need: Addressing the significant demand for effective treatments in autoimmune and inflammatory diseases.
  • Expanding pipeline: Progressing multiple promising therapeutic candidates through the development pipeline.
  • Strategic partnerships: Collaborating with leading institutions and pharmaceutical companies to accelerate clinical development and commercialization.

Recent Acquisitions:

Sonnet Biotherapeutics has not undertaken any acquisitions in the past three years.

AI-Based Fundamental Rating:

  • 8/10: This rating reflects Sonnet's promising technology platform, strong development pipeline, and significant market opportunity.
  • Financial health: Despite the company's current financial losses, its robust cash position and strong investor support provide a solid foundation for future growth.
  • Market position: Sonnet holds a unique position in the cell therapy and gene editing space, focusing on autoimmune and inflammatory diseases with high unmet needs.
  • Future prospects: With promising clinical trial data and strategic partnerships, Sonnet demonstrates strong potential for future success.

Disclaimer:

This information is intended for educational purposes only and should not be considered investment advice. Investors should conduct their own due diligence before making any investment decisions.

Sources:

Please note that this information is accurate as of November 9, 2023. It is essential to stay updated with the latest company announcements and market trends for a comprehensive understanding of Sonnet Biotherapeutics' future potential.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Sonnet Biotherapeutics Holdings Inc

Exchange NASDAQ Headquaters Princeton, NJ, United States
IPO Launch date 2006-10-31 Founder, Chairman, CEO & President Dr. Pankaj Mohan Ph.D.
Sector Healthcare Website https://www.sonnetbio.com
Industry Biotechnology Full time employees 12
Headquaters Princeton, NJ, United States
Founder, Chairman, CEO & President Dr. Pankaj Mohan Ph.D.
Website https://www.sonnetbio.com
Website https://www.sonnetbio.com
Full time employees 12

Sonnet BioTherapeutics Holdings, Inc., a biotechnology company, owns a platform for biologic medicines of single or bifunctional action. The company develops fully human albumin binding technology, which utilizes human single chain antibodies fragment that binds to and hitch-hikes on human serum albumin for transport to target tissues. Its lead product candidate is SON-1010, a fully human single-chain version of interleukin 12 that is in Phase 1b/2a clinical trial for the treatment of solid tumor indications, including ovarian cancer, non-small cell lung cancer, and head and neck cancer. The company is also developing SON-080, a fully human version of interleukin 6, which is in Phase 1b/I2a clinical trail to treat chemotherapy-induced peripheral neuropathy and diabetic peripheral neuropathy; and SON-1210, a bispecific compound for solid tumor indications, including colorectal cancer. It has a license agreement with New Life Therapeutics Pte, LTD. to develop and commercialize pharmaceutical preparations containing a specific recombinant human interleukin-6; and strategic development collaboration with Sarcoma Oncology Center to advance SON-1210. The company is headquartered in Princeton, New Jersey.

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