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Sonnet Biotherapeutics Holdings Inc (SONN)

Upturn stock ratingUpturn stock rating
$1.27
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

04/01/2025: SONN (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Analysis of Past Performance

Type Stock
Historic Profit -57.03%
Avg. Invested days 24
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 3.89M USD
Price to earnings Ratio -
1Y Target Price 20
Price to earnings Ratio -
1Y Target Price 20
Volume (30-day avg) 57257
Beta 1.01
52 Weeks Range 1.22 - 16.80
Updated Date 04/1/2025
52 Weeks Range 1.22 - 16.80
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -10.45

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -284.94%

Management Effectiveness

Return on Assets (TTM) -133.99%
Return on Equity (TTM) -285.35%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -642507
Price to Sales(TTM) 3.89
Enterprise Value -642507
Price to Sales(TTM) 3.89
Enterprise Value to Revenue 35.91
Enterprise Value to EBITDA -0.21
Shares Outstanding 3065700
Shares Floating 3007943
Shares Outstanding 3065700
Shares Floating 3007943
Percent Insiders 1.58
Percent Institutions 3.06

Analyst Ratings

Rating 5
Target Price 160
Buy -
Strong Buy 1
Buy -
Strong Buy 1
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Sonnet Biotherapeutics Holdings Inc

stock logo

Company Overview

overview logo History and Background

Sonnet Biotherapeutics Holdings, Inc. is a clinical-stage oncology company focused on developing innovative immunotherapeutic medicines. Founded to exploit targeted cytokine therapeutics, they aim to improve the safety and efficacy of cancer treatment. The company has progressed through various research and development stages, focusing on its Fully Human Albumin Binding (FHAB) platform to deliver cytokines to the tumor microenvironment.

business area logo Core Business Areas

  • Oncology Therapeutics Development: Focuses on developing and commercializing innovative immunotherapies for cancer patients using its FHAB technology.
  • FHAB Platform Technology: Developing and utilizing their proprietary FHAB platform to enhance the delivery of cytokines to tumor sites, improving treatment outcomes.

leadership logo Leadership and Structure

The company's leadership team consists of experienced professionals in the fields of oncology, drug development, and biotechnology. The organizational structure likely includes departments for research and development, clinical trials, regulatory affairs, and corporate management. Pankaj Mohan serves as CEO.

Top Products and Market Share

overview logo Key Offerings

  • SON-1010: An IL-12 FHAB intended for systemic administration. Currently in Phase 1 clinical trials. Competitors include companies developing IL-12 therapeutics or other cancer immunotherapies. Market share information is not publicly available as it is pre-commercialization.
  • SON-080: IL-6 FHAB for myelosuppression indications. Competitors are companies developing products for Chemotherapy-Induced Neutropenia (CIN) such as Amgen (Neulasta) or Coherus BioSciences (UDENYCA). Currently in pre-clinical development. Market share information is not publicly available as it is pre-clinical.

Market Dynamics

industry overview logo Industry Overview

The oncology therapeutics market is highly competitive and rapidly evolving, with significant investment in novel immunotherapies and targeted treatments. Key trends include personalized medicine, combination therapies, and the development of therapies that modulate the tumor microenvironment.

Positioning

Sonnet Biotherapeutics is positioned as a clinical-stage company focused on cytokine-based immunotherapies using its proprietary FHAB technology. Its competitive advantage lies in its ability to target cytokines to the tumor microenvironment, potentially improving efficacy and reducing systemic toxicity.

Total Addressable Market (TAM)

The global oncology market is projected to reach hundreds of billions of USD in the coming years. Sonnet aims to capture a portion of this market by developing effective immunotherapies.

Upturn SWOT Analysis

Strengths

  • Proprietary FHAB technology
  • Focus on targeted cytokine delivery
  • Experienced leadership team
  • Novel approach to cancer immunotherapy

Weaknesses

  • Early-stage clinical development
  • Limited financial resources
  • High risk associated with drug development
  • Reliance on successful clinical trial outcomes

Opportunities

  • Potential for strategic partnerships
  • Expansion into new cancer indications
  • Advancements in immuno-oncology
  • Growing demand for targeted therapies

Threats

  • Competition from larger pharmaceutical companies
  • Regulatory hurdles
  • Clinical trial failures
  • Technological advancements from competitors

Competitors and Market Share

competitor logo Key Competitors

  • NVS
  • MRK
  • BMY

Competitive Landscape

Sonnet competes with larger pharmaceutical companies and other biotechnology firms developing cancer immunotherapies. Its FHAB technology offers a potential competitive advantage, but it faces significant challenges in terms of resources and market access.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been characterized by research and development progress, clinical trial initiations, and strategic partnerships.

Future Projections: Future projections are dependent on successful clinical trial outcomes, regulatory approvals, and market acceptance of its products. Analyst estimates vary.

Recent Initiatives: Recent initiatives include advancing its clinical trials for SON-1010 and pre-clinical development of SON-080, seeking strategic partnerships, and securing funding.

Summary

Sonnet Biotherapeutics is an early-stage oncology company leveraging its FHAB platform. Its strength lies in innovative cytokine-based therapies and targeted drug delivery. The company needs to successfully navigate clinical trials and secure funding to realize its potential. Competition and regulatory hurdles remain critical challenges.

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Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Third-party Financial Data Providers
  • Industry Reports

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Investment decisions should be based on individual research and consultation with a qualified financial advisor. Market share data is estimated and may not be precise.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Sonnet Biotherapeutics Holdings Inc

Exchange NASDAQ
Headquaters Princeton, NJ, United States
IPO Launch date 2006-10-31
Founder, Chairman, CEO & President Dr. Pankaj Mohan Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 13
Full time employees 13

Sonnet BioTherapeutics Holdings, Inc., a biotechnology company, owns a platform for biologic medicines of single or bifunctional action. The company develops fully human albumin binding technology, which utilizes human single chain antibodies fragment that binds to and hitch-hikes on human serum albumin for transport to target tissues. Its lead product candidate is SON-1010, a fully human single-chain version of interleukin 12 for the treatment of solid tumor indications, including ovarian cancer, non-small cell lung cancer, and head and neck cancer. The company is also developing SON-080, a fully human version of interleukin 6 to treat chemotherapy-induced peripheral neuropathy (CIPN), and diabetic peripheral neuropathy; SON-1210, a bispecific compound for solid tumor indications, including colorectal cancer; SON-1411, a bifunctional combination of human interleukin 18 (IL-18) inhibitor binding protein and single-chain human IL-12 (IL-12) for solid tumor cancers; and SON-1400, a monofunctional fusion protein comprising the IL-18 binding protein resistant domain linked to the FHAB. It has a license agreement with New Life Therapeutics Pte, Ltd. to develop and commercialize pharmaceutical preparations containing a specific recombinant human interleukin-6; and strategic development collaboration with Sarcoma Oncology Center to advance SON-1210. The company is headquartered in Princeton, New Jersey.

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