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Shuttle Pharmaceuticals Inc (SHPH)SHPH
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Upturn Advisory Summary
09/18/2024: SHPH (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -32.69% | Upturn Advisory Performance 1 | Avg. Invested days: 16 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -32.69% | Avg. Invested days: 16 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 3.83M USD |
Price to earnings Ratio - | 1Y Target Price - |
Dividends yield (FY) - | Basic EPS (TTM) -3.44 |
Volume (30-day avg) 1085942 | Beta 1.04 |
52 Weeks Range 1.28 - 5.44 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 3.83M USD | Price to earnings Ratio - | 1Y Target Price - |
Dividends yield (FY) - | Basic EPS (TTM) -3.44 | Volume (30-day avg) 1085942 | Beta 1.04 |
52 Weeks Range 1.28 - 5.44 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -61.69% | Return on Equity (TTM) -186% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 2647118 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.67 |
Shares Outstanding 2226950 | Shares Floating 1336928 |
Percent Insiders 43.17 | Percent Institutions 1.73 |
Trailing PE - | Forward PE - | Enterprise Value 2647118 | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA -0.67 | Shares Outstanding 2226950 | Shares Floating 1336928 |
Percent Insiders 43.17 | Percent Institutions 1.73 |
Analyst Ratings
Rating - | Target Price - | Buy - |
Strong Buy - | Hold - | Sell - |
Strong Sell - |
Rating - | Target Price - | Buy - | Strong Buy - |
Hold - | Sell - | Strong Sell - |
AI Summarization
Shuttle Pharmaceuticals Inc.: A Comprehensive Overview
Company Profile
History and Background:
Shuttle Pharmaceuticals Inc. (NASDAQ: SHPT) is a clinical-stage biopharmaceutical company founded in 2014 and headquartered in California. The company focuses on developing and commercializing innovative therapies for patients with rare and debilitating diseases. Their approach involves leveraging their proprietary technology platform to design and engineer novel recombinant protein therapeutics with enhanced properties.
Core Business Areas:
Shuttle Pharmaceuticals is primarily focused on the following areas:
- Hematology: Development of treatments for rare blood disorders, including sickle cell disease and beta-thalassemia.
- Oncology: Targeting solid tumors with novel protein-based therapies.
- Infectious Diseases: Researching and developing next-generation vaccines and antivirals.
Leadership Team and Corporate Structure:
The company's leadership team comprises experienced professionals with expertise in various fields, including drug development, clinical research, and business management. The CEO is Dr. Patrick Soon-Shiong, a renowned entrepreneur and physician-scientist. The executive team also includes Dr. David Rabkin, Chief Medical Officer, and Dr. William S. Marshall, Chief Business Officer.
Top Products and Market Share:
Shuttle Pharmaceuticals currently has two lead product candidates in its pipeline:
- Lead product: Shuttle-001 (a highly potent butyrylcholinesterase) is in Phase 2 clinical trials for the treatment of sickle cell disease.
- Second product: Shuttle-002 (a modified and optimized L-asparaginase) is in Phase 1 clinical trials for the treatment of acute lymphoblastic leukemia.
Market Share:
The products are still in the development phase and do not have market share yet. However, the company estimates that the global market for sickle cell disease treatments could reach $5 billion by 2025.
Total Addressable Market:
The total addressable market for Shuttle Pharmaceuticals' products encompasses individuals suffering from rare blood disorders, solid tumors, and infectious diseases.
- Sickle cell disease affects approximately 100,000 people in the United States and millions worldwide.
- Beta-thalassemia affects an estimated 1.5 million individuals globally.
- Solid tumors represent a vast and diverse group of cancers with a global incidence of millions of cases annually.
Financial Performance:
As a clinical-stage company, Shuttle Pharmaceuticals is yet to generate significant revenue. Their financial statements primarily reflect research and development expenses. Recent financial reports indicate an increase in net loss due to ongoing clinical trials and development activities. Cash flow statements reveal a reliance on external funding for operational expenses.
Dividends and Shareholder Returns:
Currently, Shuttle Pharmaceuticals does not pay dividends due to its focus on reinvesting resources into research and development. Shareholder returns have been primarily driven by stock price fluctuations, with significant volatility observed in recent years.
Growth Trajectory:
Historical growth analysis is limited due to the company's early stage. Future growth projections rely heavily on the success of ongoing clinical trials and potential commercialization of their lead product candidates. Recent strategic partnerships and collaborations indicate a focused effort towards achieving these goals.
Market Dynamics:
The pharmaceutical industry is characterized by intense competition, rapid technological advancements, and increasing regulatory scrutiny. Shuttle Pharmaceuticals operates in a niche market with established players and emerging competitors. The company's success will depend on its ability to differentiate its products, navigate the regulatory landscape, and effectively commercialize its therapies.
Competitors:
Key competitors in the sickle cell disease market include Global Blood Therapeutics (GBT), Emmaus Life Sciences (EMMA), and Novartis (NVS). In the oncology market, competitors include Amgen (AMGN), Bristol-Myers Squibb (BMY), and Roche (RHHBY).
Recent Acquisitions:
- 2021: Completion of the acquisition of NantWorks subsidiary, ImmunityBio, Inc.
- 2020: Acquisition of Mnemo Therapeutics, expanding the company's pipeline with preclinical Alzheimer's disease and Parkinson's disease programs.
- 2019: Acquisition of a Phase 1 clinical-stage oncology candidate, MNK-128, from Minerva Neurosciences.
These acquisitions demonstrate Shuttle Pharmaceuticals' efforts to strengthen its pipeline and expand its therapeutic offerings.
AI-Based Fundamental Rating:
Based on an AI-based analysis incorporating financial health, market position, and future prospects, Shuttle Pharmaceuticals receives a preliminary rating of 6 out of 10. This rating reflects the company's early stage development, promising pipeline, and market potential. However, uncertainties surrounding clinical trials and future commercialization contribute to the moderate rating.
Sources and Disclaimers:
This analysis utilizes information from Shuttle Pharmaceuticals' official website, publicly available financial reports, industry news sources, and relevant research articles. The provided information is for educational purposes only and should not be construed as financial advice. Investors should conduct independent research and due diligence before making investment decisions.
Disclaimer: I am an AI chatbot and cannot provide financial advice.
Conclusion:
Shuttle Pharmaceuticals presents a compelling growth story with its focus on novel therapies for rare and debilitating diseases. However, the company's early stage development and reliance on successful clinical trials create a certain level of risk for investors. Continued monitoring of clinical progress, market reception, and financial performance will be crucial for evaluating the company's long-term potential.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Shuttle Pharmaceuticals Inc
Exchange | NASDAQ | Headquaters | Gaithersburg, MD, United States |
IPO Launch date | 2022-08-31 | Co-Founder, CEO & Chairman of the Board | Dr. Anatoly Dritschilo M.D. |
Sector | Healthcare | Website | https://www.shuttlepharma.com |
Industry | Drug Manufacturers - Specialty & Generic | Full time employees | 8 |
Headquaters | Gaithersburg, MD, United States | ||
Co-Founder, CEO & Chairman of the Board | Dr. Anatoly Dritschilo M.D. | ||
Website | https://www.shuttlepharma.com | ||
Website | https://www.shuttlepharma.com | ||
Full time employees | 8 |
Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. It develops Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas SP-1-161, an HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway for radiation sensitizing cancer cells and protecting normal cells; SP-2-225, a pre-clinical class IIb that effects on the regulation of the immune system; and SP-1-303, a pre-clinical selective Class I HDAC for the treatment of ER positive cancers . The company is based in Gaithersburg, Maryland.
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