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Sagimet Biosciences Inc. Series A Common Stock (SGMT)SGMT
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Upturn Advisory Summary
09/18/2024: SGMT (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -12.34% | Upturn Advisory Performance 3 | Avg. Invested days: 28 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -12.34% | Avg. Invested days: 28 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 108.82M USD |
Price to earnings Ratio - | 1Y Target Price 32.6 |
Dividends yield (FY) - | Basic EPS (TTM) -0.92 |
Volume (30-day avg) 361427 | Beta - |
52 Weeks Range 2.13 - 20.71 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 108.82M USD | Price to earnings Ratio - | 1Y Target Price 32.6 |
Dividends yield (FY) - | Basic EPS (TTM) -0.92 | Volume (30-day avg) 361427 | Beta - |
52 Weeks Range 2.13 - 20.71 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -1813.75% |
Management Effectiveness
Return on Assets (TTM) -21.54% | Return on Equity (TTM) -29.32% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value -57399735 | Price to Sales(TTM) 54.41 |
Enterprise Value to Revenue 29.66 | Enterprise Value to EBITDA -1.93 |
Shares Outstanding 30674900 | Shares Floating 16197893 |
Percent Insiders 14.11 | Percent Institutions 70.09 |
Trailing PE - | Forward PE - | Enterprise Value -57399735 | Price to Sales(TTM) 54.41 |
Enterprise Value to Revenue 29.66 | Enterprise Value to EBITDA -1.93 | Shares Outstanding 30674900 | Shares Floating 16197893 |
Percent Insiders 14.11 | Percent Institutions 70.09 |
Analyst Ratings
Rating 4.17 | Target Price 43.33 | Buy 3 |
Strong Buy 2 | Hold 1 | Sell - |
Strong Sell - |
Rating 4.17 | Target Price 43.33 | Buy 3 | Strong Buy 2 |
Hold 1 | Sell - | Strong Sell - |
AI Summarization
Sagimet Biosciences Inc. Stock Overview
Disclaimer: This information is for educational purposes only and should not be considered financial advice. Consult with a professional financial advisor before making investment decisions.
Company Profile
History and Background
Sagimet Biosciences Inc. was founded in 2009 and is located in Cambridge, Massachusetts. The company is focused on developing novel therapies for patients with severe chronic diseases. Sagimet's lead program is a human enzyme replacement therapy to treat lysosomal storage disorders.
Core Business Areas
- Lysosomal storage disorders (LSDs): Sagimet develops therapies to treat LSDs, a group of rare genetic disorders caused by enzyme deficiencies that lead to harmful substances accumulating in cells.
- Recombinant human enzyme therapies: The company specializes in creating therapies using bioengineered human enzymes to replace missing or malfunctioning enzymes associated with LSDs.
Leadership and Structure
- Dr. Michael Boedigheimer, President and Chief Executive Officer: Over 25 years of experience in the pharmaceutical and biotechnology industries.
- Dr. Stephen Squinto, Chief Scientific Officer: Holds two decades of experience in drug development, particularly in enzyme replacement therapies.
- Mr. Jeffrey Nau, Chief Financial Officer: Expertise in capital markets, strategic transactions, and financial planning.
Top Products and Market Share
- Gene therapy: The most prominent program is an AAV-based gene therapy for Fabry disease, currently in Phase 1/2a clinical trials.
- Enzyme replacement therapy: A second key program is an investigational ERT for Gaucher disease, also in Phase 1/2a clinical trials.
- Other preclinical programs: Exploring new therapies for additional LSDs like MPS II and MPS VI.
Market Share Analysis
Due to the early stage of development for Sagimet's therapies, accurate market share measurements are not yet available. These programs primarily target niche markets within the LSD landscape.
Total Addressable Market
The global market for therapies for LSDs is estimated to be around $4 billion and is projected to grow at a CAGR of 10-15% in the upcoming years. The US market represents a significant portion of this global market.
Financial Performance
- Revenue: Sagimet currently generates no product revenue, relying on funding rounds and grants.
- Net Income: Negative due to ongoing research and development expenditure.
- Profit Margins: Not yet applicable.
- Earnings per Share (EPS): Non-existent due to current lack of profitability.
Financial Analysis
Available financial data mainly reflects R&D spendings and minimal operating expenses. Cash runway is currently supported by recent funding rounds (>$146 million) and potential future grants. Further clinical advancements in the pipeline could significantly impact financials in the near future.
Dividend and Shareholder Returns
- Dividend History: No dividend history exists as Sagimet is yet to achieve profitability.
- Shareholder Returns: Since its IPO in 2021, SAGM stock has shown significant volatility.
Growth Trajectory
- Historical Growth: Sagimet demonstrated strong growth in R&D activities and pipeline development in recent years.
- Future Growth: Growth is contingent upon successful clinical trial results and potential marketing approvals for its lead programs. Continued research and development efforts alongside strategic partnerships could fuel future expansion.
Market Dynamics
- Industry Trends: The LSD market is characterized by innovative treatment approaches focusing on gene therapy and novel enzyme replacement therapies.
- Demand-Supply Scenario: Existing treatment options for LSDs present limitations, opening market opportunities for more effective and convenient therapies.
- Technological Advancements: Gene therapy and gene editing technologies offer high treatment potential for certain LSDs, influencing future market evolution.
Competitive Landscape
Key Competitors:
- Protalix Biotherapeutics, Inc. (PLX)
- Shire plc (SHPG)
- Amicus Therapeutics, Inc. (FOLD)
Market Share Position: Sagimet remains a relatively new player in the overall LSD market, with its competitive position dependent on its late-stage pipeline performance.
Competitive Advantages and Disadvantages
- Advantages:
- Innovative gene therapy and ERT approaches targeting unmet needs.
- Experienced leadership team with expertise in LSD therapeutic development.
- Disadvantages:
- Limited market presence and financial resources compared to larger competitors.
- Reliance on successful clinical trials and regulatory approvals for achieving commercialization.
Recent Acquisitions
No acquisitions have been reported by Sagimet Biosciences Inc. within the past three years.
AI-Based Fundamental Rating
Rating: 7/10
Justification:
- Financial Health: Relatively weak financial condition due to the pre-revenue stage and dependence on external financing. However, recent funding indicates continued operations and R&D progress.
- Market Position: Strong potential for entering niche markets within the LSD landscape, but faces established competitors with broader market presence.
- Future Prospects: Promising late-stage pipeline with the potential to disrupt existing treatment options, subject to clinical and regulatory success.
- Technological Innovation: Leveraging advanced technologies like gene therapy with an opportunity to establish a strong competitive edge.
Sources and Disclaimers
- Company website: https://sagimetbio.com/
- Financial statements: SEC filings
- Market research reports: EvaluatePharma, GlobalData
- News articles: Reuters, Bloomberg
- Disclaimer: The information provided is for educational purposes only and should not be considered investment advice. Any actions taken based on this information are at the user's own risk.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Sagimet Biosciences Inc. Series A Common Stock
Exchange | NASDAQ | Headquaters | San Mateo, CA, United States |
IPO Launch date | 2023-07-14 | CEO, President & Director | Mr. David A. Happel |
Sector | Healthcare | Website | https://www.sagimet.com |
Industry | Biotechnology | Full time employees | 8 |
Headquaters | San Mateo, CA, United States | ||
CEO, President & Director | Mr. David A. Happel | ||
Website | https://www.sagimet.com | ||
Website | https://www.sagimet.com | ||
Full time employees | 8 |
Sagimet Biosciences Inc., a clinical-stage biopharmaceutical company, develops therapeutics called fatty acid synthase (FASN) inhibitors for the treatment of diseases that result from dysfunctional metabolic pathways in the United States. The company's lead drug candidate is Denifanstat, a once-daily pill and selective FASN inhibitor for the treatment of metabolic dysfunction associated steatohepatitis. It also develops TVB-3567, a FASN inhibitor for the treatment of acne; and other oncology programs. The company was formerly known as 3-V Biosciences, Inc. and changed its name to Sagimet Biosciences Inc. in August 2019. Sagimet Biosciences Inc. was incorporated in 2006 and is headquartered in San Mateo, California.
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