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Sagimet Biosciences Inc. Series A Common Stock (SGMT)



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Upturn Advisory Summary
04/07/2025: SGMT (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit 3.88% | Avg. Invested days 30 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 66.97M USD | Price to earnings Ratio - | 1Y Target Price 30.5 |
Price to earnings Ratio - | 1Y Target Price 30.5 | ||
Volume (30-day avg) 481333 | Beta - | 52 Weeks Range 1.73 - 7.38 | Updated Date 04/6/2025 |
52 Weeks Range 1.73 - 7.38 | Updated Date 04/6/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.45 |
Earnings Date
Report Date 2025-03-12 | When - | Estimate -0.5853 | Actual -0.5 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -26.49% | Return on Equity (TTM) -36.92% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -84527637 | Price to Sales(TTM) 52.5 |
Enterprise Value -84527637 | Price to Sales(TTM) 52.5 | ||
Enterprise Value to Revenue 0.28 | Enterprise Value to EBITDA -1.93 | Shares Outstanding 30674900 | Shares Floating 19428281 |
Shares Outstanding 30674900 | Shares Floating 19428281 | ||
Percent Insiders 14.65 | Percent Institutions 57.75 |
Analyst Ratings
Rating 4.38 | Target Price 32.6 | Buy 3 | Strong Buy 4 |
Buy 3 | Strong Buy 4 | ||
Hold 1 | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Sagimet Biosciences Inc. Series A Common Stock
Company Overview
History and Background
Sagimet Biosciences Inc. is a clinical-stage biopharmaceutical company focused on developing novel therapeutics targeting dysfunctional metabolic pathways in diseases such as nonalcoholic steatohepatitis (NASH) and certain cancers. Founded in 2006, they went public in 2023.
Core Business Areas
- NASH Drug Development: Sagimet's primary focus is developing Denifanstat, a fatty acid synthase (FASN) inhibitor for the treatment of NASH.
- Oncology Drug Development: Developing FASN inhibitors for specific cancer indications.
Leadership and Structure
The leadership team includes key executives in drug development, clinical trials, and finance. They have a board of directors with expertise in biotech and pharmaceuticals.
Top Products and Market Share
Key Offerings
- Denifanstat: Denifanstat is Sagimet's lead product candidate for the treatment of NASH. Phase 2b clinical trial data is available. NASH market is still emerging. No specific market share at this time. Competitors include Madrigal Pharmaceuticals (MDGL) and Viking Therapeutics (VKTX).
Market Dynamics
Industry Overview
The biopharmaceutical industry is highly competitive, with significant investments in research and development. The NASH market is large and growing, with significant unmet medical need.
Positioning
Sagimet is positioning itself as a leader in FASN inhibitor therapeutics for NASH and oncology. They are competing with larger, more established pharmaceutical companies.
Total Addressable Market (TAM)
NASH TAM is estimated to be $30-40 billion. Sagimet is positioning itself to capture a significant portion of this market with Denifanstat, pending successful clinical trials and regulatory approval.
Upturn SWOT Analysis
Strengths
- Novel FASN inhibitor technology
- Promising Phase 2b clinical trial results for Denifanstat
- Experienced management team
Weaknesses
- Limited financial resources compared to larger pharmaceutical companies
- Dependence on a single lead product candidate
- Clinical trial risks and regulatory hurdles
Opportunities
- Potential for FDA approval of Denifanstat for NASH
- Expansion into other therapeutic areas with FASN inhibitors
- Strategic partnerships with larger pharmaceutical companies
Threats
- Competition from other NASH therapies in development
- Unsuccessful clinical trials
- Changes in regulatory requirements
Competitors and Market Share
Key Competitors
- MDGL
- VKTX
- AKRO
Competitive Landscape
Sagimet faces competition from larger pharmaceutical companies with more resources and established products. Their competitive advantage lies in their novel FASN inhibitor technology and promising clinical trial results. None of the products are approved at this time, so all are zero
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth is characterized by progress in clinical trials and securing funding.
Future Projections: Future growth depends on the successful completion of clinical trials and regulatory approval for Denifanstat. Analyst estimates will be available as the company progresses.
Recent Initiatives: Recent initiatives include the completion of Phase 2b clinical trials and preparation for Phase 3 trials.
Summary
Sagimet Biosciences is a clinical-stage company with potential in the NASH market. The strength of the company is its novel drug Denifanstat and promising clinical results. The company's weaknesses include limited financial resources and the risks associated with drug development. Sagimet needs to closely monitor its cash burn rate and navigate regulatory hurdles to succeed.
Similar Companies

GILD

Gilead Sciences Inc



GILD

Gilead Sciences Inc

MDGL

Madrigal Pharmaceuticals Inc



MDGL

Madrigal Pharmaceuticals Inc

VKTX

Viking Therapeutics Inc



VKTX

Viking Therapeutics Inc
Sources and Disclaimers
Data Sources:
- Company filings, Investor presentations, Market research reports
Disclaimers:
This analysis is for informational purposes only and should not be considered investment advice. Financial data is subject to change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Sagimet Biosciences Inc. Series A Common Stock
Exchange NASDAQ | Headquaters San Mateo, CA, United States | ||
IPO Launch date 2023-07-14 | CEO, President & Director Mr. David A. Happel | ||
Sector Healthcare | Industry Biotechnology | Full time employees 14 | Website https://www.sagimet.com |
Full time employees 14 | Website https://www.sagimet.com |
Sagimet Biosciences Inc., a clinical-stage biopharmaceutical company, develops novel therapeutics called fatty acid synthase (FASN) inhibitors for the treatment of diseases that result from dysfunctional metabolic pathways in the United States. The company's lead drug candidate is Denifanstat, an oral, once-daily pill and selective FASN inhibitor for the treatment of metabolic dysfunction-associated steatohepatitis. It also develops TVB-3567, a FASN inhibitor for the treatment of acne; and other oncology programs, such as various solid tumor and glioblastoma. The company was formerly known as 3-V Biosciences, Inc. and changed its name to Sagimet Biosciences Inc. in August 2019. Sagimet Biosciences Inc. was incorporated in 2006 and is headquartered in San Mateo, California.
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