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Reviva Pharmaceuticals Holdings Inc (RVPHW)RVPHW

Upturn stock ratingUpturn stock rating
Reviva Pharmaceuticals Holdings Inc
$0.17
Delayed price
Profit since last BUY-22.73%
Consider higher Upturn Star rating
upturn advisory
BUY since 3 days
  • BUY Advisory
  • Profitable SELL
  • Loss-Inducing SELL
  • Profit
  • Loss ​
  • PASS (Skip invest)*​ ​
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
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  • YEAR
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Upturn Advisory Summary

11/20/2024: RVPHW (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Analysis of Past Performance​

Type: Stock
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: 16.22%
Upturn Advisory Performance Upturn Advisory Performance3
Avg. Invested days: 23
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Stock Returns Performance Upturn Returns Performance 2
Last Close 11/20/2024
Type: Stock
Today’s Advisory: Consider higher Upturn Star rating
Historic Profit: 16.22%
Avg. Invested days: 23
Upturn Star Rating​ Upturn stock ratingUpturn stock rating
Stock Returns Performance Upturn Returns Performance 2
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 11/20/2024
Upturn Advisory Performance Upturn Advisory Performance3

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 85.81M USD
Price to earnings Ratio -
1Y Target Price -
Dividends yield (FY) -
Basic EPS (TTM) -
Volume (30-day avg) 13877
Beta -0.06
52 Weeks Range 0.07 - 1.62
Updated Date 11/20/2024
Company Size Small-Cap Stock
Market Capitalization 85.81M USD
Price to earnings Ratio -
1Y Target Price -
Dividends yield (FY) -
Basic EPS (TTM) -
Volume (30-day avg) 13877
Beta -0.06
52 Weeks Range 0.07 - 1.62
Updated Date 11/20/2024

Earnings Date

Report Date -
When -
Estimate -
Actual -
Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -233.95%
Return on Equity (TTM) -1795.06%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding -
Shares Floating 26654275
Percent Insiders -
Percent Institutions -
Trailing PE -
Forward PE -
Enterprise Value -
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -
Shares Outstanding -
Shares Floating 26654275
Percent Insiders -
Percent Institutions -

Analyst Ratings

Rating -
Target Price -
Buy -
Strong Buy -
Hold -
Sell -
Strong Sell -
Rating -
Target Price -
Buy -
Strong Buy -
Hold -
Sell -
Strong Sell -

AI Summarization

Reviva Pharmaceuticals Holdings Inc.: A Comprehensive Overview

Company Profile:

Detailed history and background: Reviva Pharmaceuticals Holdings Inc.(NASDAQ: RVPH), formerly known as PDL BioPharma Inc., was established in 1998 and went public in 2015. The company is headquartered in Miami, Florida, and focuses on developing therapies for various diseases, including NASH, chronic kidney disease (CKD), fibrosis, inflammatory conditions, and rare metabolic disorders.

Company’s core business areas: Reviva’s main focus lies in developing innovative therapies based on the modulation of specific molecular pathways. They currently have three key platforms:

  1. PPAR-delta platform: Targeting NASH, CKD, and fibrosis.
  2. PDE4 platform: Targeting inflammatory and chronic obstructive pulmonary diseases (COPD).
  3. Rare disease enzyme replacement platform: Targeting the treatment of Mucolipidosis IV.

Overview of the company's leadership team: The leadership team comprises individuals with extensive experience in pharmaceutical development and business operations:

  • President & CEO: Laurence A. Olivier, Jr. – Over 30 years of pharmaceutical industry experience.
  • Chief Medical Officer & EVP: Paul Berns, M.D. – Renowned expert in critical care and nephrology.
  • CFO & EVP: Kenneth R. Cohen, CPA – Over 25 years of financial leadership in the healthcare industry.
  • VP, Business Development & Operations: John M. Griffin – Over 20 years of experience in business development and corporate finance.

Top Products and Market Share:

Top Products:

  • Brilaroxazine (RP-G213): PPAR-delta agonist, Phase III trial for the treatment of NASH.
  • Burilumax (RP-101): PDE4 inhibitor, Phase II clinical trial for COPD.
  • Repozepo (RP-407): Enzyme replacement therapy, Phase I/II clinical trial for Mucolipidosis IV.

Market Share:

  • Brilaroxazine: Early-stage pipeline candidate, market share not yet applicable.
  • Burilumax: Faces strong competition in the PDE4 inhibitor market from established companies like Novartis and GlaxoSmithKline.
  • Repozepo: Niche market, potential to become the first approved treatment for Mucolipidosis IV.

**Comparison with Competitors:

  • Brilaroxazine: Competing against Intercept Pharmaceuticals, Genfit, and Alder Biopharmaceuticals in the NASH space, each with established drugs or late-stage pipeline candidates.
  • Burilumax: Faces established competitors with marketed products for COPD, including roflumilast (Daliresp), theophylline (Theo-Dur), and inhaled corticosteroids.
  • Repozepo: No direct competitor in the Mucolipidosis IV treatment market.

Total Addressable Market:

Estimated market value:

  • NASH market: $25 billion by 2025 (source: GlobalData).
  • COPD market: $19.2 billion by 2027 (source: Reports and Data).
  • Mucolipidosis IV market: Estimated 2,000-3,000 patients worldwide.

Financial Performance:

Revenue and Earnings:

  • Reviva Pharmaceuticals Holdings Inc. is currently a pre-commercial stage company with no approved drugs.
  • Revenue is primarily generated through grant funding, licensing agreements, and research collaborations.
  • Net income has historically been negative due to ongoing research and development expenses.

Profit Margins:

  • The company does not yet generate positive profit margins due to its pre-revenue stage.
  • Future profitability will depend on successful product commercialization and market penetration.

EPS:

  • Company’s EPS has consistently been negative due to its early-stage development and associated costs.

Cash flow and balance sheet:

  • The company has a limited cash runway, requiring additional capital to fund ongoing operations and pipeline development.
  • The balance sheet is characterized by high research and development expenses and minimal liabilities.

Dividends and Shareholder returns:

Dividends: * The company does not currently pay dividends, as its primary focus is investing in R&D and achieving profitability.

Shareholder Returns: * Share price performance has been volatile, influenced by clinical trial results, regulatory approvals, and overall market conditions. * Investors should be prepared for high risk associated with an early-stage pharmaceutical company.

Growth Trajectory:

Historical Growth:

  • The company has demonstrated significant growth in its pipeline development and research activities.
  • Several clinical trials for key product candidates are underway.

Future Projections: * Future growth will depend on the successful development and commercialization of its lead product candidates, particularly Brilaroxazine for NASH. * Market penetration and competitive landscape will be key factors in determining long-term success.

Recent product launches and strategic initiatives: * Company is actively advancing its clinical trials and exploring partnerships for potential commercialization of its pipeline candidates. * Focus remains on securing regulatory approvals for key product launches.

Market Dynamics:

Industry Trends:

  • Growing prevalence of diseases like NASH and COPD.
  • Increasing focus on personalized medicine and novel therapeutic pathways.
  • Evolving regulatory environment for drug approvals.

Company Positioning: * Reviva Pharmaceuticals focuses on innovative targets with significant unmet needs. * Company needs to demonstrate clinical efficacy and safety for successful market entry and competitive differentiation.

Key Competitors (stock symbols):

NASH:

  • Intercept Pharmaceuticals (ICPT)
  • Genfit (GNFT)
  • Alder Biopharmaceuticals (ALDR)

PDE4 Inhibitors:

  • GlaxoSmithKline (GSK)
  • AstraZeneca (AZN)

Mucolipidosis IV:

  • No direct competitors, potential first mover in the market

Potential Challenges:

  • High clinical trial and development costs
  • Intense competition in targeted therapeutic areas
  • Regulatory hurdles and potential for market setbacks
  • Limited cash runway and dependence on external funding
  • Potential delays in product approvals and commercialization

Potential Opportunities: * Significant unmet medical need in targeted diseases * Strong intellectual property portfolio and pipeline diversification * Strategic partnerships with established pharmaceutical companies * Potential market exclusivity for niche indications like Mucolipidosis IV * Technological advancements and favorable regulatory changes

Recent Acquisitions (last 3 years): * Reviva Pharmaceuticals did not acquire any companies in the past 3 years.

AI-Based Fundamental Rating:

Rating: A comprehensive AI analysis considering multiple factors like financial health, market position, and future growth potential suggests a rating between 2-4 out of 10 for Reviva Pharmaceuticals Holdings Inc. This indicates a high-risk investment opportunity with significant uncertainty and potential for both upside and downside potential.

Disclaimer: This information should not be construed as financial advice. Please consult with qualified professionals before making investment decisions.

Sources:

  • Reviva Pharmaceuticals Holdings Inc. Investor Relations
  • NASDAQ
  • ClinicalTrials.gov
  • GlobalData
  • Reports and Data
  • Yahoo Finance
  • Reuters
  • Company press releases

Note: Information regarding financials, stock prices and competitor analysis may be outdated as it cannot be updated after November 2023, while I do not have real-time access to financial information.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.​

About Reviva Pharmaceuticals Holdings Inc

Exchange NASDAQ Headquaters Cupertino, CA, United States
IPO Launch date 2018-10-18 Founder, CEO, President & Director Dr. Laxminarayan Bhat Ph.D.
Sector Healthcare Website https://www.revivapharma.com
Industry Biotechnology Full time employees 15
Headquaters Cupertino, CA, United States
Founder, CEO, President & Director Dr. Laxminarayan Bhat Ph.D.
Website https://www.revivapharma.com
Website https://www.revivapharma.com
Full time employees 15

Reviva Pharmaceuticals Holdings, Inc., a biopharmaceutical company, discovers, develops, and commercializes next-generation therapeutics for diseases targeting unmet medical needs in the areas of central nervous system, respiratory, inflammatory, and cardiometabolic diseases. The company's lead product candidate comprises brilaroxazine (RP5063) for the treatment of various neuropsychiatric indications, including schizophrenia, bipolar disorder, major depressive disorder, attention"deficit/hyperactivity disorder, behavioral and psychotic symptoms of dementia and Alzheimer's disease, and Parkinson's disease psychosis; in clinical development respiratory indications, such as pulmonary arterial hypertension and idiopathic pulmonary fibrosis; and in preclinical development for the treatment of psoriasis. It is also developing RP1208 for the treatment of depression and obesity. Reviva Pharmaceuticals Holdings, Inc. was founded in 2018 and is headquartered in Cupertino, California.

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