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Cartesian Therapeutics Inc. (RNAC)



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Upturn Advisory Summary
04/04/2025: RNAC (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -33.33% | Avg. Invested days 23 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 259.07M USD | Price to earnings Ratio - | 1Y Target Price 37.33 |
Price to earnings Ratio - | 1Y Target Price 37.33 | ||
Volume (30-day avg) 103686 | Beta 0.83 | 52 Weeks Range 9.12 - 41.87 | Updated Date 04/5/2025 |
52 Weeks Range 9.12 - 41.87 | Updated Date 04/5/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -4.49 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin -198.97% | Operating Margin (TTM) 2523.32% |
Management Effectiveness
Return on Assets (TTM) -6% | Return on Equity (TTM) -7029.26% |
Valuation
Trailing PE - | Forward PE 25.45 | Enterprise Value 59926867 | Price to Sales(TTM) 6.66 |
Enterprise Value 59926867 | Price to Sales(TTM) 6.66 | ||
Enterprise Value to Revenue 1.54 | Enterprise Value to EBITDA -1.17 | Shares Outstanding 25907100 | Shares Floating 9459460 |
Shares Outstanding 25907100 | Shares Floating 9459460 | ||
Percent Insiders 59.28 | Percent Institutions 26.66 |
Analyst Ratings
Rating 4.25 | Target Price 43 | Buy 2 | Strong Buy 4 |
Buy 2 | Strong Buy 4 | ||
Hold 2 | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Cartesian Therapeutics Inc.

Company Overview
History and Background
Cartesian Therapeutics, Inc. is a clinical-stage biotechnology company pioneering RNA cell therapy for autoimmune diseases. Founded in 2016, the company focuses on developing engineered cell therapies that address the underlying causes of these diseases. The company has transitioned from preclinical research to clinical trials.
Core Business Areas
- RNA Cell Therapy: Developing and commercializing RNA cell therapies targeting autoimmune diseases.
- Descartes-DNA platform: Using its proprietary Descartes-DNA platform to design and manufacture RNA cell therapies. The Descartes-DNA platform is a cell engineering platform where cells are engineered ex vivo using mRNA.
Leadership and Structure
Dr. Murat V. Kalayoglu is the President and CEO. The company has a board of directors and a management team focused on research, development, and clinical operations.
Top Products and Market Share
Key Offerings
- Descartes-08: An RNA-engineered CAR-T cell therapy in clinical development for the treatment of generalized myasthenia gravis (gMG). There is no market share data available as it is still in development. Competitors include companies developing other CAR-T therapies, as well as those offering existing treatments such as acetylcholinesterase inhibitors and immunotherapies.
- Descartes-30: An RNA-engineered CAR-T cell therapy in clinical development for the treatment of relapsed or refractory multiple myeloma (RRMM). There is no market share data available as it is still in development. Competitors include companies developing other CAR-T therapies, as well as those offering existing treatments such as proteasome inhibitors, immunomodulatory drugs, and chemotherapy.
Market Dynamics
Industry Overview
The biotechnology industry, particularly the cell and gene therapy sector, is experiencing rapid growth driven by technological advancements and increasing investment. The autoimmune disease market is a large and growing segment with significant unmet medical needs.
Positioning
Cartesian Therapeutics is positioned as an innovator in RNA cell therapy for autoimmune diseases. Its competitive advantage lies in its Descartes-DNA platform, which enables precise and controlled engineering of cells.
Total Addressable Market (TAM)
The total addressable market for autoimmune disease therapies is estimated to be in the tens of billions of dollars annually. Cartesian is positioned to capture a portion of this market by offering potentially curative therapies for specific autoimmune conditions.
Upturn SWOT Analysis
Strengths
- Proprietary Descartes-DNA platform
- Focus on RNA cell therapy
- Strong leadership team
- Clinical-stage assets
Weaknesses
- Limited revenue stream (clinical stage)
- High research and development costs
- Reliance on successful clinical trial outcomes
- Relatively small company size
Opportunities
- Successful clinical trial results
- Partnerships with larger pharmaceutical companies
- Expansion into new autoimmune indications
- Advancements in cell therapy technology
Threats
- Clinical trial failures
- Regulatory hurdles
- Competition from established pharmaceutical companies
- Patent disputes
Competitors and Market Share
Key Competitors
- BLUE
- CRSP
- EDIT
Competitive Landscape
Cartesian differentiates itself with its Descartes-DNA platform for RNA cell therapy, targeting a specific approach to treat autoimmune diseases and cancers. Major competitors have diverse portfolios of gene editing and cell therapy technologies.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth is characterized by preclinical and early clinical development activities.
Future Projections: Future growth depends on successful completion of clinical trials and regulatory approvals. Analyst estimates depend on specific clinical data, with potential for significant revenue upon commercialization.
Recent Initiatives: Recent initiatives include advancing clinical trials for Descartes-08 and Descartes-30, presenting clinical data at scientific conferences, and securing funding.
Summary
Cartesian Therapeutics is a clinical-stage biotech company focused on RNA cell therapy for autoimmune diseases, possessing a novel technology platform and addressing substantial unmet medical needs. Its success hinges on favorable clinical trial results, adept navigation of the regulatory landscape, and its ability to carve out a significant share in a highly competitive market. Given it's a clinical-stage company, investors should monitor developments closely. The company is high risk and high reward.
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GILD

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Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Industry Reports
- Analyst Reports
Disclaimers:
This analysis is for informational purposes only and should not be considered investment advice. Financial data and market information are subject to change. Invest at your own risk.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Cartesian Therapeutics Inc.
Exchange NASDAQ | Headquaters Frederick, MD, United States | ||
IPO Launch date 2016-06-22 | President, CEO & Director Dr. Carsten Brunn Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 66 | |
Full time employees 66 |
Cartesian Therapeutics, Inc., a clinical-stage biotechnology company, engages in the provision of mRNA cell therapies for the treatment of autoimmune diseases. The company's lead product candidate is Descartes-08, an autologous mRNA CAR-T directed against the B cell maturation antigen (BCMA) for the treatment of autoimmune diseases, currently under Phase 2b clinical development for generalized myasthenia gravis, systemic lupus erythematosus, as well as rare pediatric disease designation for the treatment of juvenile dermatomyositis. It develops Descartes-15, an autologous anti-BCMA mRNA CAR-T to treat autoimmune diseases such as relapsed/refractory multiple myeloma. Cartesian Therapeutics, Inc. is headquartered in Frederick, Maryland.
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