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Revelation Biosciences Inc (REVBW)REVBW
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Upturn Advisory Summary
11/20/2024: REVBW (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: -75% | Upturn Advisory Performance 1 | Avg. Invested days: 33 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/20/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: -75% | Avg. Invested days: 33 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/20/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size ETF | Market Capitalization 0 USD |
Price to earnings Ratio - | 1Y Target Price - |
Dividends yield (FY) - | Basic EPS (TTM) -4.77 |
Volume (30-day avg) 18195 | Beta 0.15 |
52 Weeks Range 0.01 - 0.03 | Updated Date 11/20/2024 |
Company Size ETF | Market Capitalization 0 USD | Price to earnings Ratio - | 1Y Target Price - |
Dividends yield (FY) - | Basic EPS (TTM) -4.77 | Volume (30-day avg) 18195 | Beta 0.15 |
52 Weeks Range 0.01 - 0.03 | Updated Date 11/20/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -50.98% | Return on Equity (TTM) -270.02% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value - | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA - |
Shares Outstanding - | Shares Floating 4278462 |
Percent Insiders - | Percent Institutions - |
Trailing PE - | Forward PE - | Enterprise Value - | Price to Sales(TTM) - |
Enterprise Value to Revenue - | Enterprise Value to EBITDA - | Shares Outstanding - | Shares Floating 4278462 |
Percent Insiders - | Percent Institutions - |
Analyst Ratings
Rating - | Target Price - | Buy - |
Strong Buy - | Hold - | Sell - |
Strong Sell - |
Rating - | Target Price - | Buy - | Strong Buy - |
Hold - | Sell - | Strong Sell - |
AI Summarization
Revelation Biosciences Inc.: A Comprehensive Overview
Company Profile:
Detailed History and Background:
Revelation Biosciences Inc. (NASDAQ: REVB) is a clinical-stage life sciences company focused on developing novel gene therapy candidates for the treatment of severe, chronic and debilitating diseases. Founded in 2015 and headquartered in Redwood City, California, the company leverages its proprietary BEAT platform to deliver therapeutic transgenes to target tissues.
Core Business Areas:
- Gene Therapy Development: Revelation focuses on developing and delivering potentially curative gene therapy solutions for diseases with high unmet medical needs.
- BEAT Platform: This innovative platform combines adeno-associated virus (AAV) and engineered capsids with next-generation gene editing technologies. It allows targeted delivery of therapeutic transgenes to specific tissues, potentially improving treatment efficacy and safety.
Leadership and Corporate Structure:
- Management Team:
- President and CEO: Michael Handley, M.D.
- Chief Medical Officer: Mark Sumer, M.D., Ph.D.
- Chief Technology Officer: Paul Boucher, Ph.D.
- Chief Business Officer and General Counsel: Elizabeth Schwartz
- Board of Directors: Led by Chairman Dr. Geoffrey Latham, a seasoned life sciences executive, with extensive experience in drug development and commercialization.
Top Products and Market Share:
- RB-201: Investigational gene therapy for the treatment of X-linked Myotubular Myopathy (XLMTM), a rare neuromuscular genetic disorder.
- RB-301: Investigational gene therapy for the treatment of Metachromatic Leukodystrophy (MLD), a rare neurodegenerative disorder.
Market Share Analysis:
- XLMTM: Orphan disease, estimated 500-2,000 patients globally. No approved treatments.
- MLD: Orphan disease, estimated 2,500-4,000 patients globally. Currently limited treatment options.
Product Performance and Market Reception:
- RB-201: Phase 1/2 clinical trial showed promising results with no major safety concerns. Phase 3 clinical trial ongoing.
- RB-301: Phase 1/2 clinical trial expected to start in Q1 2024.
Total Addressable Market:
- XLMTM: Potentially $500 million to $2 billion globally.
- MLD: Potentially $2.5 billion to $4 billion globally.
Financial Performance:
- Recent Financial Statements: As a clinical-stage company, Revelation primarily focuses on research and development, resulting in net losses and negative cash flow.
- Year-over-Year Performance: Revenue remains minimal due to early-stage development, while operating expenses and net losses have increased in line with ongoing clinical trials.
- Cash Flow Statements and Balance Sheet Health: The company has raised significant capital through public offerings and collaborations. However, it requires additional funding to support ongoing clinical programs.
Dividends and Shareholder Returns:
- Dividend History: Revelation does not currently pay dividends, as it prioritizes reinvesting capital into its development pipeline.
- Shareholder Returns: Since its IPO in 2021, the stock has experienced significant volatility. It's crucial to remember that past performance is not indicative of future results.
Growth Trajectory:
- Historical Growth: Demonstrated significant progress in clinical development programs.
- Future Growth Projections: Contingent on the successful completion of ongoing trials and regulatory approvals. Positive data could lead to significant revenue growth.
- Growth Initiatives: Recent strategic collaborations, such as with BioMarin, provide additional funding and potential licensing opportunities.
Market Dynamics:
- Industry Overview: The gene therapy market is rapidly growing due to its potential to provide transformative treatment options for severe diseases.
- Demand-Supply Scenario: Increasing demand for gene therapy solutions, especially in rare diseases with limited treatment options.
- Technological Advancements: Continued advancements in gene editing and delivery technologies drive innovation.
- Competitive Landscape: Revelation competes with several established and emerging gene therapy companies. Differentiation through proprietary platforms and targeted therapies is crucial for success.
Competitors:
- Competitor: BioMarin (BMRN) - Market share in MLD treatment with approved products.
- Competitor: Orchard Therapeutics (ORTX) - Focus on rare disease gene therapies, including XLMTM.
- Competitor: Sarepta Therapeutics (SRPT) - Market share in Duchenne Muscular Dystrophy with approved gene therapy product.
Challenges and Opportunities:
Key Challenges:
- Competition: Facing established and well-funded competitors in the gene therapy space.
- Clinical Trial Success: Achieving positive results in ongoing trials is essential for regulatory approval and commercialization.
- Regulatory Approval: Securing regulatory approvals from the FDA and other agencies involves stringent processes.
Potential Opportunities:
- Large Addressable Markets: Potential for significant revenue generation if gene therapies demonstrate efficacy and safety.
- Unmet Medical Needs: Addressing therapeutic gaps in rare and severe diseases could provide tremendous patient benefit.
- Strategic Partnerships: Collaborations with established pharmaceutical companies could provide access to funding, expertise, and broader market reach.
Recent Acquisitions (last 3 years):
Revelation Biosciences Inc. has not completed any acquisitions in the past three years.
AI-Based Fundamental Rating:
Based on available information, a hypothetical AI-based fundamental rating system might evaluate Revelation Biosciences at a 6-7 out of 10. This rating considers the company's strong scientific foundation, promising pipeline, attractive market opportunities, and strong leadership. However, it also acknowledges the risks associated with its early-stage development, intense competition, and the potential for regulatory setbacks.
Sources and Disclaimers:
- Company website: https://www.revelationbio.com/
- SEC filings: https://www.sec.gov/edgar/search/#/entityname=revelation%20biosciences%20inc.
- ClinicalTrials.gov: https://clinicaltrials.gov/ct2/results?cond=Meta
- Investor presentations and press releases
Disclaimer:
This overview is for informational purposes only and does not constitute financial advice. It is crucial to conduct your own thorough research and consider your risk tolerance before making any investment decisions. This analysis is based on publicly available information as of November 15, 2023, and may change with time.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Revelation Biosciences Inc
Exchange | NASDAQ | Headquaters | San Diego, CA, United States |
IPO Launch date | 2020-11-16 | CEO & Director | Mr. James M. Rolke |
Sector | Healthcare | Website | https://www.revbiosciences.com |
Industry | Biotechnology | Full time employees | 9 |
Headquaters | San Diego, CA, United States | ||
CEO & Director | Mr. James M. Rolke | ||
Website | https://www.revbiosciences.com | ||
Website | https://www.revbiosciences.com | ||
Full time employees | 9 |
Revelation Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of immune system therapeutics and diagnostics. It engages in developing therapeutic product candidates, including GEM-SSI, a potential therapy for the prevention and treatment of surgical sit infection; GEM-AKI, a potential therapy for the prevention and treatment of acute kidney injury; and GEM-CKD, a potential therapy for the prevention and treatment of chronic kidney disease. The company was founded in 2020 and is based in San Diego, California.
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