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Pyxis Oncology Inc (PYXS)
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Upturn Advisory Summary
02/20/2025: PYXS (2-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit 176.36% | Avg. Invested days 35 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 76.12M USD | Price to earnings Ratio - | 1Y Target Price 8.83 |
Price to earnings Ratio - | 1Y Target Price 8.83 | ||
Volume (30-day avg) 597281 | Beta 1.07 | 52 Weeks Range 1.23 - 6.85 | Updated Date 02/21/2025 |
52 Weeks Range 1.23 - 6.85 | Updated Date 02/21/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.06 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -398.68% |
Management Effectiveness
Return on Assets (TTM) -21.06% | Return on Equity (TTM) -39.34% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -43404609 | Price to Sales(TTM) 4.71 |
Enterprise Value -43404609 | Price to Sales(TTM) 4.71 | ||
Enterprise Value to Revenue 5.08 | Enterprise Value to EBITDA 1.09 | Shares Outstanding 59465700 | Shares Floating 39234299 |
Shares Outstanding 59465700 | Shares Floating 39234299 | ||
Percent Insiders 24.57 | Percent Institutions 41.52 |
AI Summary
Pyxis Oncology Inc.: A Comprehensive Overview
Company Profile:
History and Background:
Pyxis Oncology Inc. (Nasdaq: PYXS) is a clinical-stage biopharmaceutical company based in Boston, Massachusetts. Founded in 2019, Pyxis is focused on developing innovative therapies for patients with cancer. The company leverages its proprietary Antibody-Drug Conjugate (ADC) technology platform to design and develop highly targeted cancer therapies.
Core Business Areas:
Pyxis's core business areas include:
- Developing and commercializing ADC-based therapies for the treatment of various cancers.
- Utilizing its ADC platform to partner with other pharmaceutical companies.
Leadership Team and Corporate Structure:
- Dr. Michael Fritsch, President and CEO
- Dr. David E. Smith, Chief Medical Officer
- Dr. David M. Goldenberg, Chief Scientific Officer
- Board of Directors comprises experienced professionals from the pharmaceutical and biotechnology industries.
Top Products and Market Share:
Pyxis is currently in the clinical development stage and does not have any marketed products. Its lead product candidate, PYX-201, is an ADC targeting HER2-positive cancers. PYX-201 is currently in Phase 1 clinical trials.
Total Addressable Market:
The global market for cancer therapies is estimated to be over $150 billion and is expected to grow significantly in the coming years.
Financial Performance:
As a clinical-stage company, Pyxis does not yet generate significant revenue. The company's financial performance is primarily focused on R&D expenses and cash burn.
Dividends and Shareholder Returns:
Pyxis is not currently paying dividends and has not yet achieved profitability.
Growth Trajectory:
Pyxis is expected to experience significant growth as its lead product candidate, PYX-201, progresses through clinical trials and potentially receives regulatory approval.
Market Dynamics:
The oncology market is highly competitive and constantly evolving. Pyxis faces competition from established pharmaceutical companies and other biotech companies developing novel cancer therapies.
Competitors:
- Seattle Genetics (SGEN)
- Immunomedics (IMMU)
- ADC Therapeutics (ADCT)
- Daiichi Sankyo (OTCPK:DSKYF)
Potential Challenges and Opportunities:
Challenges:
- Demonstrating the efficacy and safety of its lead product candidate in clinical trials.
- Obtaining regulatory approval for its product candidates.
- Successfully commercializing its products in a competitive market.
Opportunities:
- Growing demand for innovative cancer therapies.
- Potential for partnerships with larger pharmaceutical companies.
- Expanding its product pipeline through internal research and development or acquisitions.
Recent Acquisitions:
Pyxis has not made any acquisitions in the last three years.
AI-Based Fundamental Rating:
Rating: 6/10
Justification:
Pyxis is a promising company with a strong pipeline of ADC-based cancer therapies. However, the company is still in the early stages of development and faces significant challenges in terms of clinical development, regulatory approval, and commercialization. The AI-based rating takes into account the company's financial health, market position, and future prospects.
Sources and Disclaimers:
- Information for this overview was gathered from Pyxis Oncology Inc.'s website, SEC filings, and other publicly available sources.
- This information is not intended as investment advice. Please consult with a financial professional before making any investment decisions.
Disclaimer: I am an AI chatbot and cannot provide financial advice.
About Pyxis Oncology Inc
Exchange NASDAQ | Headquaters Boston, MA, United States | ||
IPO Launch date 2021-10-08 | CEO, President & Director Dr. Lara S. Sullivan M.D., MBA | ||
Sector Healthcare | Industry Biotechnology | Full time employees 54 | Website https://www.pyxisoncology.com |
Full time employees 54 | Website https://www.pyxisoncology.com |
Pyxis Oncology, Inc., a clinical stage company, engages in the development of therapeutics to treat cancers. Its lead antibody-drug conjugates (ADC) product candidate is PYX-201, an investigational novel ADC consisting of human immunoglobulin G1 (IgG1), which is in Phase 1 clinical trial to treat patients with relapsed or refractory solid tumors; and lead immuno-oncology (IO) product candidate is PYX-106, an investigational fully human IgG1 Siglec-15-targeting antibody that is in Phase 1 clinical trial to treat patients with advanced solid tumors. The company is also developing PYX-107, a CD40 agonist with demonstrated anti-cancer activity in patients who previously progressed on PD-(L)1 inhibitors, which is in Phase 2 clinical trial for the treatment of solid tumors, such as soft tissue sarcomas, esophageal and gastroesophageal junction, cancers, and melanoma in combination with chemotherapy, radiation therapy, and immunotherapy. It has in-license agreement with Pfizer Inc. to develop and commercialize ADC product candidates directed to certain licensed targets, including PYX-201 and PYX-203, and products containing the ADC product candidates; and Biosion USA, Inc. for development, manufacture, and commercialization of PYX-106, an IO product candidate. Pyxis Oncology, Inc. was incorporated in 2018 and is headquartered in Boston, Massachusetts.
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