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Protagonist Therapeutics Inc (PTGX)PTGX
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Upturn Advisory Summary
09/18/2024: PTGX (4-star) is a STRONG-BUY. BUY since 86 days. Profits (40.17%). Updated daily EoD!
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Strong Buy |
Profit: 269.93% | Upturn Advisory Performance 4 | Avg. Invested days: 61 |
Profits based on simulation | Stock Returns Performance 5 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Strong Buy |
Profit: 269.93% | Avg. Invested days: 61 |
Upturn Star Rating | Stock Returns Performance 5 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 4 |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 2.72B USD |
Price to earnings Ratio 16.51 | 1Y Target Price 50.67 |
Dividends yield (FY) - | Basic EPS (TTM) 2.72 |
Volume (30-day avg) 610522 | Beta 2.17 |
52 Weeks Range 13.72 - 48.00 | Updated Date 09/18/2024 |
Company Size Mid-Cap Stock | Market Capitalization 2.72B USD | Price to earnings Ratio 16.51 | 1Y Target Price 50.67 |
Dividends yield (FY) - | Basic EPS (TTM) 2.72 | Volume (30-day avg) 610522 | Beta 2.17 |
52 Weeks Range 13.72 - 48.00 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin 53.26% | Operating Margin (TTM) -930.96% |
Management Effectiveness
Return on Assets (TTM) 20.35% | Return on Equity (TTM) 40.69% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE 16.51 | Forward PE 25.84 |
Enterprise Value 2092378912 | Price to Sales(TTM) 8.53 |
Enterprise Value to Revenue 6.56 | Enterprise Value to EBITDA 13.45 |
Shares Outstanding 58904600 | Shares Floating 43684818 |
Percent Insiders 1.18 | Percent Institutions 102.43 |
Trailing PE 16.51 | Forward PE 25.84 | Enterprise Value 2092378912 | Price to Sales(TTM) 8.53 |
Enterprise Value to Revenue 6.56 | Enterprise Value to EBITDA 13.45 | Shares Outstanding 58904600 | Shares Floating 43684818 |
Percent Insiders 1.18 | Percent Institutions 102.43 |
Analyst Ratings
Rating 4.5 | Target Price 40.75 | Buy 3 |
Strong Buy 3 | Hold - | Sell - |
Strong Sell - |
Rating 4.5 | Target Price 40.75 | Buy 3 | Strong Buy 3 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Protagonist Therapeutics Inc.: A Comprehensive Overview
Company Profile
History and Background:
Protagonist Therapeutics Inc. (PTX) is a clinical-stage biopharmaceutical company founded in 2009 and headquartered in New York City. PTX focuses on the development of innovative peptide-based therapies for patients with severe gastrointestinal (GI) diseases.
Core Business Areas:
- Gastrointestinal (GI) Diseases: PTX's primary focus is developing oral therapies for GI diseases with high unmet medical needs. Their pipeline includes treatments for inflammatory bowel disease (IBD), short bowel syndrome (SBS), and eosinophilic esophagitis (EoE).
- Peptide-based Therapeutics: PTX's drug development platform utilizes novel peptide technologies to improve the delivery and efficacy of therapeutic molecules. They engineer peptides to overcome the limitations of traditional oral medications, such as poor absorption and degradation.
Leadership and Corporate Structure:
- Management Team: PTX is led by industry veterans with extensive experience in drug development and commercialization. The leadership team includes:
- Dinesh V. Patel, Ph.D., President and Chief Executive Officer
- Michael K. Baker, Chief Operating Officer and Chief Financial Officer
- Michael H. Cohen, M.D., Ph.D., Chief Medical Officer
- David J. Smith, Ph.D., Chief Scientific Officer
- Board of Directors: The board comprises experts in biopharmaceutical development, finance, and law.
Top Products and Market Share:
- Top Products:
- PTG-100: A long-acting glucagon-like peptide-2 (GLP-2) analog for the treatment of SBS. Phase 3 clinical trials are ongoing.
- PTG-200: A once-daily oral peptide for the treatment of IBD. Phase 2 clinical trials are ongoing.
- PTG-300: A novel peptide for the treatment of EoE. Phase 1 clinical trials are ongoing.
- Market Share: PTX's products are still in the development stage and do not have any market share yet. However, the company targets markets with significant unmet needs, offering potential for future market leadership.
Total Addressable Market:
The global market for GI drugs is estimated to be worth over $200 billion and is expected to grow significantly in the coming years. PTX's target markets, such as IBD and SBS, represent a substantial portion of this market with high unmet needs.
Financial Performance:
- Revenue: PTX is currently a pre-commercial stage company with no product sales.
- Net Income: PTX has not yet achieved profitability.
- Profit Margins: N/A
- Earnings per Share (EPS): N/A
- Financial Health: PTX has a strong cash position with approximately $175 million in cash and equivalents as of June 30, 2023. They have raised significant capital through public offerings and partnerships.
Year-over-Year Financial Performance:
- Revenue and net income are not applicable as PTX has no commercialized products.
- Operating expenses are increasing as the company progresses through clinical trials.
Dividends and Shareholder Returns:
- Dividend History: PTX does not currently pay dividends.
- Shareholder Returns: PTX stock has experienced volatility in recent years, reflecting the company's development stage and clinical trial progress.
Growth Trajectory:
- Historical Growth: PTX has achieved significant progress in its clinical development programs, advancing multiple candidates into Phase 2 and 3 trials.
- Future Growth Projections: Analysts expect PTX to achieve significant revenue growth upon commercialization of its lead product candidates.
- Recent Developments: PTX recently announced positive top-line results from a Phase 2b trial of PTG-200 for induction of remission in moderately to severely active ulcerative colitis.
Market Dynamics:
- Industry Trends: The GI market is characterized by increasing demand for innovative therapies with improved efficacy and safety profiles.
- Demand-Supply Scenarios: There is a significant unmet need for effective treatments in PTX's target markets.
- Technological Advancements: PTX is at the forefront of peptide-based drug development, offering potential advantages over traditional therapies.
Competitive Landscape:
- Key Competitors: PTX competes with several pharmaceutical companies developing treatments for GI diseases, including AbbVie, Pfizer, and Takeda.
- Market Share Comparison: PTX does not have market share yet, but their product candidates have the potential to compete effectively in their respective markets.
- Competitive Advantages: PTX's differentiated peptide-based platform and focus on high-unmet-need indications provide potential competitive advantages.
Potential Challenges and Opportunities:
- Challenges: PTX faces challenges common to emerging biopharmaceutical companies, including navigating the complex regulatory landscape and achieving commercial success.
- Opportunities: PTX has the potential to establish itself as a leader in the GI market with its innovative therapies and strong clinical development pipeline.
Recent Acquisitions (last 3 years):
Protagonist
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Protagonist Therapeutics Inc
Exchange | NASDAQ | Headquaters | Newark, CA, United States |
IPO Launch date | 2016-08-11 | CEO, President, Secretary & Director | Dr. Dinesh V. Patel Ph.D. |
Sector | Healthcare | Website | https://www.protagonist-inc.com |
Industry | Biotechnology | Full time employees | 125 |
Headquaters | Newark, CA, United States | ||
CEO, President, Secretary & Director | Dr. Dinesh V. Patel Ph.D. | ||
Website | https://www.protagonist-inc.com | ||
Website | https://www.protagonist-inc.com | ||
Full time employees | 125 |
Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide-based drugs for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide (PTG-300), an injectable hepcidin mimetic that completed phase 2 clinical trials for the treatment of polycythemia vera and other blood disorders; and JNJ-2113, an orally delivered investigational drug to block biological pathways that completed phase 2b clinical trials for the treatment of moderate-to-severe plaque psoriasis; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company has a license and collaboration agreement with Takeda to commercialize rusfertide; and JNJ Innovative Medicines to co-develop Interleukin-23 receptor antagonist compound JNJ-2113. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.
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