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Praxis Precision Medicines Inc (PRAX)



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Upturn Advisory Summary
04/07/2025: PRAX (2-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -17.65% | Avg. Invested days 34 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 658.33M USD | Price to earnings Ratio - | 1Y Target Price 99.27 |
Price to earnings Ratio - | 1Y Target Price 99.27 | ||
Volume (30-day avg) 616499 | Beta 2.68 | 52 Weeks Range 30.00 - 91.83 | Updated Date 04/6/2025 |
52 Weeks Range 30.00 - 91.83 | Updated Date 04/6/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -10.21 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -856.97% |
Management Effectiveness
Return on Assets (TTM) -43.82% | Return on Equity (TTM) -70.98% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 263704360 | Price to Sales(TTM) 76.97 |
Enterprise Value 263704360 | Price to Sales(TTM) 76.97 | ||
Enterprise Value to Revenue 30.83 | Enterprise Value to EBITDA -6.86 | Shares Outstanding 20163200 | Shares Floating 16083216 |
Shares Outstanding 20163200 | Shares Floating 16083216 | ||
Percent Insiders 0.46 | Percent Institutions 112.34 |
Analyst Ratings
Rating 4.5 | Target Price 162.6 | Buy 3 | Strong Buy 6 |
Buy 3 | Strong Buy 6 | ||
Hold 1 | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Praxis Precision Medicines Inc

Company Overview
History and Background
Praxis Precision Medicines, Inc. is a biopharmaceutical company focused on developing therapies for central nervous system (CNS) disorders. Founded in 2015, Praxis has advanced multiple programs into clinical development.
Core Business Areas
- Neurology: Development of therapies for epilepsy, including focal onset seizures and other rare epilepsies.
- Neuropsychiatry: Research and development of treatments for mood and anxiety disorders.
Leadership and Structure
The leadership team includes executives with experience in drug development and commercialization. The company operates with a structure focused on research and clinical development.
Top Products and Market Share
Key Offerings
- PRAX-19: An investigational antisense oligonucleotide targeting a specific subunit of the GABA-A receptor. Currently in clinical trials. Competitors: Multiple pharmaceutical companies developing antiseizure medications.
- PRAX-562: An investigational molecule targeting the neuronal hyperxcitability, or hyperexcitability, that causes neurological disorder symptoms. Currently in clinical trials. Competitors: Other pharmaceutical companies developing neurological disorder medications
Market Dynamics
Industry Overview
The pharmaceutical industry focused on CNS disorders is a large and competitive market with significant unmet medical needs.
Positioning
Praxis is positioned as a precision medicines company, targeting specific genetic and molecular drivers of CNS disorders. This personalized approach aims to improve treatment efficacy.
Total Addressable Market (TAM)
The TAM for CNS disorders is substantial. Praxis is positioned to address specific segments of this market with its targeted therapies.
Upturn SWOT Analysis
Strengths
- Precision medicine approach
- Experienced management team
- Diverse pipeline of drug candidates
- Focus on unmet medical needs
Weaknesses
- Clinical trial risks
- Limited commercialized products
- Reliance on partnerships and funding
- High R&D expenses
Opportunities
- Expansion of pipeline into new CNS disorders
- Partnerships with larger pharmaceutical companies
- Successful clinical trial outcomes
- Regulatory approvals and commercialization of products
Threats
- Clinical trial failures
- Competition from established pharmaceutical companies
- Changes in regulatory landscape
- Patent expirations
Competitors and Market Share
Key Competitors
- EPIX
- AZN
- GSK
Competitive Landscape
Praxis is a smaller player compared to established pharmaceutical giants. Its competitive advantage lies in its precision medicine approach and focus on specific patient populations.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Praxis' growth is measured by advancements in clinical trials and expansion of the pipeline.
Future Projections: Future growth projections rely on successful clinical trial results and regulatory approvals. Analyst estimates are based on potential product sales.
Recent Initiatives: Recent initiatives include advancing PRAX-19 and PRAX-562 through clinical development, and focusing on strategic pipeline expansion.
Summary
Praxis Precision Medicines is a clinical-stage biopharmaceutical company with a focus on CNS disorders. While the company is still in the development phase and faces significant clinical trial risks, it has a compelling precision medicine approach and an experienced team. Future success hinges on positive clinical trial outcomes and regulatory approvals. The company needs to maintain its cash runway and manage its R&D expenses effectively.
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Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Analyst Reports
- Market Research Reports
Disclaimers:
This analysis is for informational purposes only and should not be considered financial advice. The data provided is based on publicly available information, and its accuracy cannot be guaranteed.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Praxis Precision Medicines Inc
Exchange NASDAQ | Headquaters Boston, MA, United States | ||
IPO Launch date 2020-10-16 | President, CEO & Director Mr. Marcio Silva De'Souza M.B.A. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 116 | Website https://praxismedicines.com |
Full time employees 116 | Website https://praxismedicines.com |
Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. The company offers cerebrum, a small molecule platform for CNS small molecule therapies and solidus, an antisense oligonucleotide platform to discover and develop antisense oligonucleotide. It is developing ulixacaltamide, a small molecule inhibitor of T-type calcium channels that is in Phase III clinical trial for the treatment of essential tremor; vormatrigine, a small molecule targeting the hyperexcitable state of sodium-channels in the brain to treat focal onset epilepsy; relutrigine for the treatment of developmental and epileptic encephalopathies; PRAX-020; and PRAX-050. In addition, the company develops elsunersen, a clinical-stage ASO designed to regulate NaV1.2 expression for the treatment of SCN2A-DEE; PRAX-080; PRAX-090; and PRAX-100. It has a license agreement with RogCon Inc.; and research collaboration and license agreement with Ionis Pharmaceuticals, Inc. The company was incorporated in 2015 and is based in Boston, Massachusetts.
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