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Predictive Oncology Inc (POAI)

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Upturn Advisory Summary
12/16/2025: POAI (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $3
1 Year Target Price $3
| 0 | Strong Buy |
| 0 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -3.82% | Avg. Invested days 27 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 20.19M USD | Price to earnings Ratio - | 1Y Target Price 3 |
Price to earnings Ratio - | 1Y Target Price 3 | ||
Volume (30-day avg) 1 | Beta 1.35 | 52 Weeks Range 3.88 - 32.10 | Updated Date 01/9/2026 |
52 Weeks Range 3.88 - 32.10 | Updated Date 01/9/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -141.32 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Revenue by Geography
Geography revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -90654.07% |
Management Effectiveness
Return on Assets (TTM) -128.8% | Return on Equity (TTM) -746.03% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 24649762 | Price to Sales(TTM) 12.13 |
Enterprise Value 24649762 | Price to Sales(TTM) 12.13 | ||
Enterprise Value to Revenue 14.81 | Enterprise Value to EBITDA -0.51 | Shares Outstanding 3393516 | Shares Floating 1833008 |
Shares Outstanding 3393516 | Shares Floating 1833008 | ||
Percent Insiders 4.92 | Percent Institutions 0.15 |
Upturn AI SWOT
Predictive Oncology Inc

Company Overview
History and Background
Predictive Oncology Inc. (formerly IntelliBio, Inc.) was founded with the goal of advancing personalized medicine. The company has undergone several name changes and strategic shifts, focusing on leveraging artificial intelligence and machine learning to analyze complex biological data for improved cancer treatment outcomes. Significant milestones include its rebranding and the development of its AI-powered platform.
Core Business Areas
- AI-Powered Drug Discovery and Development: Utilizing its proprietary AI platform, PEM (Predictive, Efficacy, and Mechanistic) systems, the company aims to accelerate the identification and validation of novel drug targets and therapeutic candidates for various cancers. This involves analyzing vast datasets to predict drug efficacy and patient response.
- Personalized Medicine Solutions: The company is focused on developing solutions that can predict a patient's response to specific therapies, enabling oncologists to make more informed treatment decisions. This includes leveraging genomic and proteomic data.
Leadership and Structure
Predictive Oncology Inc. is led by a management team with experience in biotechnology, AI, and business operations. The exact organizational structure is typical of a biotechnology company, with departments for research and development, clinical affairs, business development, and administration. Specific leadership roles and detailed organizational charts are typically found in their investor relations materials.
Top Products and Market Share
Key Offerings
- PEM Systems (Predictive, Efficacy, and Mechanistic): This is Predictive Oncology Inc.'s core AI platform. It is designed to analyze complex biological data to identify novel drug targets, predict drug efficacy, and understand the mechanistic basis of drug action. The platform aims to significantly reduce the time and cost associated with traditional drug discovery. Market share data for such a specialized platform in its early stages is not readily available. Competitors in the broader AI drug discovery space include companies like Atomwise, Recursion Pharmaceuticals, and BenevolentAI.
Market Dynamics
Industry Overview
The oncology market is characterized by a continuous need for more effective and personalized treatments. The drug discovery and development sector is undergoing a digital transformation, with increasing adoption of AI and machine learning to overcome the high failure rates and long timelines associated with traditional methods. The personalized medicine segment is growing rapidly due to advances in genomics and diagnostics.
Positioning
Predictive Oncology Inc. positions itself as a leader in AI-driven oncology solutions. Its competitive advantage lies in its proprietary PEM systems, which aim to provide deeper insights into drug efficacy and patient stratification. The company focuses on early-stage drug discovery and the development of predictive analytics for treatment selection.
Total Addressable Market (TAM)
The TAM for AI in drug discovery and personalized medicine is substantial and growing. Estimates vary widely, but the global AI in drug discovery market is projected to reach tens of billions of dollars in the coming years. Predictive Oncology Inc. is targeting segments within this large TAM, focusing on specific cancer indications and therapeutic areas where its AI platform can demonstrate significant value.
Upturn SWOT Analysis
Strengths
- Proprietary AI platform (PEM systems) for drug discovery and predictive analytics.
- Focus on a high-growth market segment (AI in oncology and personalized medicine).
- Potential to accelerate drug development timelines and reduce costs.
- Experienced management team with relevant industry backgrounds.
Weaknesses
- Early-stage company with a history of strategic pivots.
- Limited commercialized products and revenue streams.
- Reliance on significant future funding for research and development.
- Challenges in validating AI-driven predictions in real-world clinical settings.
Opportunities
- Increasing adoption of AI in pharmaceutical R&D.
- Growing demand for personalized cancer treatments.
- Potential for strategic partnerships with larger pharmaceutical companies.
- Expansion into new therapeutic areas and cancer types.
- Development of companion diagnostics based on predictive analytics.
Threats
- Intense competition from established pharmaceutical companies and other AI drug discovery startups.
- Regulatory hurdles for novel drug approvals.
- Data privacy and security concerns related to patient data.
- Technological obsolescence if AI advancements outpace the company's platform.
- Difficulty in securing consistent and sufficient funding.
Competitors and Market Share
Key Competitors
- Recursion Pharmaceuticals (RXRX)
- BenevolentAI (BNNLF)
- Atomwise (Private)
- Exscientia (EXAI)
Competitive Landscape
Predictive Oncology Inc. competes in a rapidly evolving and capital-intensive field. While its proprietary PEM systems offer a unique approach, it faces competition from well-funded companies with established research pipelines and larger data reserves. Its advantage lies in its specific focus on predictive efficacy and mechanistic understanding, aiming for a more targeted approach to drug discovery. However, it needs to demonstrate superior speed, accuracy, and cost-effectiveness compared to competitors.
Growth Trajectory and Initiatives
Historical Growth: Predictive Oncology Inc.'s historical growth has been characterized by technological development and strategic repositioning rather than consistent revenue growth. The company has been building its AI platform and seeking to establish its market presence in the AI-driven drug discovery space.
Future Projections: Future growth projections are contingent on the successful development and commercialization of its AI platform, securing partnerships, and potentially progressing drug candidates through clinical trials. Analyst estimates, if available, would reflect potential revenue streams from licensing agreements, collaborations, and future product sales. These projections are inherently speculative for early-stage biotech firms.
Recent Initiatives: Recent initiatives likely include further development and refinement of the PEM systems, forging strategic alliances with pharmaceutical or academic institutions, and exploring new applications for its AI technology in oncology. The company may also be focused on expanding its data sets for AI training and validation.
Summary
Predictive Oncology Inc. is an AI-driven biotechnology company focused on revolutionizing cancer treatment through advanced predictive analytics and drug discovery. Its core strength lies in its proprietary PEM platform, which aims to accelerate R&D and personalize medicine. However, as an early-stage entity, it faces significant challenges including intense competition, the need for substantial funding, and the inherent risks of drug development. Success hinges on validating its technology, securing strategic partnerships, and navigating the complex regulatory landscape.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company Investor Relations materials (SEC Filings - 10-K, 10-Q)
- Industry analysis reports (e.g., from market research firms)
- Financial news and data providers (e.g., Bloomberg, Refinitiv, Yahoo Finance)
Disclaimers:
This analysis is based on publicly available information and general industry knowledge. It is not intended as financial advice. Investors should conduct their own due diligence and consult with a qualified financial advisor before making any investment decisions. Market share data for early-stage companies and AI platforms is often proprietary or estimated. Competitors listed are based on their involvement in AI drug discovery and oncology.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Predictive Oncology Inc
Exchange NASDAQ | Headquaters Pittsburgh, PA, United States | ||
IPO Launch date 2018-01-29 | CEO & Chairman Mr. Raymond F. Vennare | ||
Sector Technology | Industry Software - Infrastructure | Full time employees 23 | Website https://predictive-oncology.com |
Full time employees 23 | Website https://predictive-oncology.com | ||
Predictive Oncology Inc., a knowledge and science-driven company, applies artificial intelligence (AI) to support the discovery and development of cancer therapies. It operates through two segments, Pittsburgh and Eagan. The Pittsburgh segment provides services that include the application of AI using its proprietary biobank of 150,000+ tumor samples. This segment also creates proprietary 3D culture models used in drug development. Its Eagan segment produces the FDA-cleared STREAMWAY System and associated products for automated medical fluid waste management and patient-to-drain medical fluid disposal. Predictive Oncology Inc. has a strategic collaboration with Every Cure to identify and prioritize drugs for repurposing. The company was formerly known as Precision Therapeutics Inc. and changed its name to Predictive Oncology Inc. in June 2019. Predictive Oncology Inc. was incorporated in 2002 and is headquartered in Pittsburgh, Pennsylvania.

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