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Vaxcyte Inc (PCVX)



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Upturn Advisory Summary
04/01/2025: PCVX (2-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit 17.21% | Avg. Invested days 46 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 4.15B USD | Price to earnings Ratio - | 1Y Target Price 128.44 |
Price to earnings Ratio - | 1Y Target Price 128.44 | ||
Volume (30-day avg) 1868179 | Beta 1.02 | 52 Weeks Range 30.12 - 121.06 | Updated Date 04/1/2025 |
52 Weeks Range 30.12 - 121.06 | Updated Date 04/1/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -3.8 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -14.47% | Return on Equity (TTM) -20.41% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 3191091311 | Price to Sales(TTM) - |
Enterprise Value 3191091311 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -14.43 | Shares Outstanding 128762000 | Shares Floating 119166306 |
Shares Outstanding 128762000 | Shares Floating 119166306 | ||
Percent Insiders 0.5 | Percent Institutions 111.76 |
Analyst Ratings
Rating 4.82 | Target Price 149.89 | Buy 2 | Strong Buy 9 |
Buy 2 | Strong Buy 9 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
Vaxcyte Inc

Company Overview
History and Background
Vaxcyte, Inc. was founded in 2013. The company focuses on developing novel and improved vaccines to prevent or treat infectious diseases. The company became public in 2020 via an IPO.
Core Business Areas
- Vaccine Development: Vaxcyte focuses on developing conjugated and multi-valent vaccines to address unmet needs in infectious disease prevention. Their focus is on the prevention of invasive pneumococcal disease.
Leadership and Structure
Grant Pickering is the CEO. The company has a board of directors and operates with a typical biotech structure focused on research and development.
Top Products and Market Share
Key Offerings
- PCV (Pneumococcal Conjugate Vaccine) Pipeline: Vaxcyte's lead product candidates are next-generation pneumococcal conjugate vaccines (PCVs) targeting broader coverage of serotypes than currently available vaccines. VAX-24 is designed to cover 24 serotypes. Competitors include Pfizer (Prevnar 20), and Merck.
Market Dynamics
Industry Overview
The vaccine market is characterized by high barriers to entry, significant regulatory oversight, and a growing demand for preventative healthcare solutions. It is dominated by a few large players but has room for innovation.
Positioning
Vaxcyte is positioning itself as an innovator in the vaccine space, focusing on creating vaccines with broader coverage and improved immunogenicity compared to existing products.
Total Addressable Market (TAM)
The global pneumococcal vaccine market is significant, estimated to be in the billions of dollars annually. Vaxcyte aims to capture a substantial portion of this TAM with its next-generation vaccines.
Upturn SWOT Analysis
Strengths
- Novel vaccine technology platform
- Strong pipeline of vaccine candidates
- Experienced management team
- Targeting a large unmet need
Weaknesses
- Limited commercialized products
- Reliance on clinical trial success
- Cash burn rate associated with R&D
- Dependence on partnerships for manufacturing and distribution
Opportunities
- Positive clinical trial results leading to regulatory approvals
- Partnerships with larger pharmaceutical companies
- Expansion into new vaccine targets
- Increasing global demand for vaccines
Threats
- Clinical trial failures
- Regulatory hurdles
- Competition from established vaccine manufacturers
- Patent disputes
Competitors and Market Share
Key Competitors
- PFE
- MRK
Competitive Landscape
Vaxcyte faces competition from established players like Pfizer and Merck, but aims to differentiate itself with broader serotype coverage and improved immunogenicity. The market is very competitive.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historically, growth is measured by pipeline advancement, clinical trial progress, and capital raising activities rather than revenue generation.
Future Projections: Future growth depends on successful clinical trial outcomes, regulatory approvals, and potential commercialization of their vaccine candidates. Analyst estimates are highly dependent on these factors.
Recent Initiatives: Recent initiatives include ongoing clinical trials for VAX-24 and other pipeline candidates, expansion of manufacturing capabilities, and collaborations with research institutions.
Summary
Vaxcyte is a development-stage biotech company with a promising pipeline of novel vaccines. Its success hinges on positive clinical trial results and securing regulatory approvals. The company's ability to compete with larger, established players depends on demonstrating superior efficacy and safety of its vaccine candidates. Investors should watch cash burn and efficacy data closely.
Similar Companies
- MRNA
- BNTX
- NVAX
- PFE
- MRK
Sources and Disclaimers
Data Sources:
- Company filings
- Analyst reports
- Industry publications
Disclaimers:
This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be based on individual research and consultation with a qualified financial advisor. Market share estimates are approximate and may vary depending on the source.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Vaxcyte Inc
Exchange NASDAQ | Headquaters San Carlos, CA, United States | ||
IPO Launch date 2020-06-12 | Co-Founder, CEO & Director Mr. Grant E. Pickering M.B.A. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 414 | Website https://vaxcyte.com |
Full time employees 414 | Website https://vaxcyte.com |
Vaxcyte, Inc., a clinical-stage biotechnology vaccine company, develops conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent carrier-sparing investigational pneumococcal conjugate vaccine (PCV) for the prevention of invasive pneumococcal disease (IPD). The company also develops VAX-31, a 31-valent, carrier-sparing investigational PCV being developed for the prevention of IPD in adults and children. VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting the keystone pathogen responsible for periodontitis; and VAX-GI to prevent dysentery and shigellosis. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.
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