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OptiNose (OPTN)



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Upturn Advisory Summary
04/01/2025: OPTN (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Performance
Type Stock | Historic Profit -30.28% | Avg. Invested days 29 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 92.64M USD | Price to earnings Ratio - | 1Y Target Price 18 |
Price to earnings Ratio - | 1Y Target Price 18 | ||
Volume (30-day avg) 124478 | Beta -0.3 | 52 Weeks Range 4.82 - 21.45 | Updated Date 04/1/2025 |
52 Weeks Range 4.82 - 21.45 | Updated Date 04/1/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.12 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date 2025-03-05 | When Before Market | Estimate -0.84 | Actual -0.03 |
Profitability
Profit Margin -27.54% | Operating Margin (TTM) 1.58% |
Management Effectiveness
Return on Assets (TTM) -8.63% | Return on Equity (TTM) -1050.5% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 137011928 | Price to Sales(TTM) 1.18 |
Enterprise Value 137011928 | Price to Sales(TTM) 1.18 | ||
Enterprise Value to Revenue 1.75 | Enterprise Value to EBITDA -4.33 | Shares Outstanding 10124300 | Shares Floating 6924275 |
Shares Outstanding 10124300 | Shares Floating 6924275 | ||
Percent Insiders 7.12 | Percent Institutions 72.16 |
Analyst Ratings
Rating 4.5 | Target Price 30.75 | Buy 2 | Strong Buy 2 |
Buy 2 | Strong Buy 2 | ||
Hold - | Sell - | Strong Sell - | |
Strong Sell - |
Upturn AI SWOT
OptiNose

Company Overview
History and Background
OptiNose was founded in 2000. The company focuses on developing and commercializing products for patients treated by ear, nose, and throat (ENT) specialists and allergists. Its key milestones include FDA approval and commercial launch of its XHANCE product.
Core Business Areas
- Pharmaceuticals: Develops and commercializes pharmaceutical products using its bi-directional nasal delivery technology.
Leadership and Structure
OptiNose's leadership team includes key executives responsible for research and development, commercialization, and finance. The organizational structure is typical of a publicly traded pharmaceutical company.
Top Products and Market Share
Key Offerings
- XHANCE: XHANCE is a nasal spray approved for the treatment of nasal polyps. Competitors include nasal steroids from companies like GSK (GSK), Teva (TEVA), and Regeneron/Sanofi (REGN/SNY). Market share data is dynamic and depends on prescription data and competitive dynamics, it is estimated around 25% in its class based on number of prescriptions.
Market Dynamics
Industry Overview
The pharmaceutical industry focused on ENT and allergy treatments is competitive, with several players developing and marketing nasal sprays and other medications.
Positioning
OptiNose is positioned as a specialty pharmaceutical company focused on innovative nasal drug delivery. Its competitive advantage lies in its bi-directional nasal delivery technology.
Total Addressable Market (TAM)
The TAM for nasal polyp treatment is estimated to be billions of dollars. OptiNose, with its XHANCE product, aims to capture a significant share of this market.
Upturn SWOT Analysis
Strengths
- Proprietary bi-directional nasal delivery technology
- Approved product (XHANCE)
- Focus on underserved ENT market
Weaknesses
- Reliance on single product (XHANCE) for revenue
- Limited financial resources compared to larger pharmaceutical companies
- Dependence on successful commercialization of XHANCE
Opportunities
- Expanding indications for XHANCE
- Developing new products using bi-directional nasal delivery technology
- Partnering with larger pharmaceutical companies
Threats
- Competition from existing and new nasal sprays
- Pricing pressures from insurance companies
- Regulatory challenges
Competitors and Market Share
Key Competitors
- GSK
- TEVA
- REGN
- SNY
Competitive Landscape
OptiNose's advantages include its novel drug delivery technology and focus on the ENT market. Disadvantages include its smaller size and limited resources compared to larger pharmaceutical companies.
Major Acquisitions
Growth Trajectory and Initiatives
Historical Growth: Historical growth data would be populated here if available.
Future Projections: Future growth projections depend on analyst estimates and would be populated here if available.
Recent Initiatives: Recent strategic initiatives include expanding the sales force for XHANCE and exploring new indications for the product.
Summary
OptiNose is a specialty pharmaceutical company with a focus on ENT. It has a unique delivery system in XHANCE, which helps with market penetration. The company's biggest weakness is its dependence on only one product. Optinose should look out for competitive pressure and pricing strategies from insurance companies.
Similar Companies
- GSK
- TEVA
- REGN
- SNY
Sources and Disclaimers
Data Sources:
- Company reports, SEC filings, market research reports, analyst estimates
Disclaimers:
This analysis is based on available information and is not financial advice. Market conditions and company performance can change.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About OptiNose
Exchange NASDAQ | Headquaters Yardley, PA, United States | ||
IPO Launch date 2017-10-13 | CEO & Director Dr. Ramy A. Mahmoud M.D., M.P.H. | ||
Sector Healthcare | Industry Drug Manufacturers - Specialty & Generic | Full time employees 127 | Website https://www.optinose.com |
Full time employees 127 | Website https://www.optinose.com |
OptiNose, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of products for patients treated by ear, nose, throat, and allergy specialists in the United States. The company offers XHANCE, a therapeutic product utilizing its proprietary exhalation delivery system (EDS) that delivers a topically acting corticosteroid for the treatment of chronic rhinosinusitis with nasal polyps, as well as is in Phase IIIb clinical trial for treatment of chronic sinusitis; and Onzetra Xsail, a powder EDS device. It has a license agreement with Currax Pharmaceuticals LLC for the commercialization of Onzetra Xsail. The company was founded in 2000 and is headquartered in Yardley, Pennsylvania.
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