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Upturn stock ratingUpturn stock rating
OPK logo

Opko Health Inc (OPK)

Upturn stock ratingUpturn stock rating
$1.66
Delayed price
Profit since last BUY2.47%
upturn advisory
SELL
SELL since 1 day
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Upturn Advisory Summary

04/01/2025: OPK (1-star) is a SELL. SELL since 1 days. Profits (2.47%). Updated daily EoD!

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Analysis of Past Performance

Type Stock
Historic Profit -41.79%
Avg. Invested days 38
Today’s Advisory SELL
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/01/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.14B USD
Price to earnings Ratio -
1Y Target Price 3.99
Price to earnings Ratio -
1Y Target Price 3.99
Volume (30-day avg) 6735986
Beta 1.71
52 Weeks Range 1.15 - 2.04
Updated Date 04/1/2025
52 Weeks Range 1.15 - 2.04
Updated Date 04/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.08

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Revenue by Geography

Geography revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -7.46%
Operating Margin (TTM) -18.05%

Management Effectiveness

Return on Assets (TTM) -8.12%
Return on Equity (TTM) -3.86%

Valuation

Trailing PE -
Forward PE 64.52
Enterprise Value 1214143459
Price to Sales(TTM) 1.6
Enterprise Value 1214143459
Price to Sales(TTM) 1.6
Enterprise Value to Revenue 1.7
Enterprise Value to EBITDA 8.98
Shares Outstanding 671550016
Shares Floating 253987028
Shares Outstanding 671550016
Shares Floating 253987028
Percent Insiders 59.26
Percent Institutions 29.91

Analyst Ratings

Rating 4.33
Target Price 3.96
Buy 4
Strong Buy 2
Buy 4
Strong Buy 2
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Opko Health Inc

stock logo

Company Overview

overview logo History and Background

Opko Health Inc. was founded in 1991 as IVAX Corporation, which later merged with Teva Pharmaceutical Industries in 2006. The company was later renamed Opko Health Inc. and has focused on diagnostics, pharmaceuticals, and medical devices.

business area logo Core Business Areas

  • Pharmaceuticals: Focuses on developing and commercializing pharmaceutical products, including Rayaldee for secondary hyperparathyroidism.
  • Diagnostics: Develops and commercializes diagnostic tests, including 4Kscore test for prostate cancer risk.
  • Medical Devices: Involved in the research and development of medical devices.

leadership logo Leadership and Structure

Dr. Phillip Frost serves as the Chairman and CEO. The company has a typical corporate structure with various executive vice presidents overseeing different business segments.

Top Products and Market Share

overview logo Key Offerings

  • Rayaldee: Rayaldee is a treatment for secondary hyperparathyroidism (SHPT) in adults with chronic kidney disease (CKD). While specific market share data is difficult to obtain, its competitors include calcimimetics like Sensipar (Amgen) and other Vitamin D analogs. The most recent report indicates approximately $120 Million Revenue.
  • 4Kscore Test: The 4Kscore test is a blood test used to assess the risk of aggressive prostate cancer. The competitors include Prostate Health Index (PHI) and PCA3 tests. Market Share is relatively small.

Market Dynamics

industry overview logo Industry Overview

The healthcare industry is characterized by constant innovation, regulatory scrutiny, and significant competition. It is driven by aging populations, increasing prevalence of chronic diseases, and advancements in technology.

Positioning

Opko Health Inc. occupies a niche position with its focus on diagnostics and niche pharmaceutical products. Its competitive advantage is its 4Kscore test and Rayaldee product, although it faces competition from larger pharmaceutical companies.

Total Addressable Market (TAM)

The TAM for prostate cancer diagnostics and secondary hyperparathyroidism treatments is estimated to be in the billions of dollars. Opko is positioned to capture a small, but growing, percentage of this TAM.

Upturn SWOT Analysis

Strengths

  • Proprietary diagnostic tests (e.g., 4Kscore)
  • Established pharmaceutical product (Rayaldee)
  • Experienced leadership
  • Strategic acquisitions

Weaknesses

  • Reliance on key products
  • History of losses and negative cash flow
  • High debt levels
  • Litigation risks
  • Regulatory hurdles

Opportunities

  • Expansion of diagnostic testing services
  • Development of new pharmaceutical products
  • Strategic partnerships
  • Market growth in key therapeutic areas

Threats

  • Competition from larger pharmaceutical companies
  • Regulatory changes impacting drug pricing
  • Patent expirations
  • Economic downturn affecting healthcare spending
  • Clinical trial failures

Competitors and Market Share

competitor logo Key Competitors

  • AMGN
  • HOLX
  • PRGO

Competitive Landscape

Opko faces significant competition from larger, more established companies in the pharmaceutical and diagnostics industries. Its competitive advantage lies in its innovative products, but it needs to improve its financial performance to compete effectively.

Major Acquisitions

Bio-Reference Laboratories

  • Year: 2015
  • Acquisition Price (USD millions): 1470
  • Strategic Rationale: Expanded OPKO's diagnostics business significantly, providing a platform for growth in laboratory testing services.

Growth Trajectory and Initiatives

Historical Growth: Historical growth has been inconsistent due to product development challenges and market competition.

Future Projections: Analyst estimates vary widely, reflecting uncertainty about the company's future prospects and regulatory hurdles.

Recent Initiatives: Recent initiatives include focusing on growing sales of Rayaldee and expanding the availability of the 4Kscore test.

Summary

Opko Health is a company with promising diagnostic and pharmaceutical assets but faces significant financial challenges. While the 4Kscore test and Rayaldee offer growth potential, the company's high debt levels and history of losses are concerning. Opko needs to improve its profitability and demonstrate consistent growth to gain investor confidence and navigate competitive threats.

Similar Companies

  • AMGN
  • HOLX
  • PRGO
  • BRLI

Sources and Disclaimers

Data Sources:

  • Company Filings
  • Analyst Reports
  • Third-Party Market Research

Disclaimers:

The information provided is for informational purposes only and should not be considered investment advice. Market share data is approximate and may vary depending on the source.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Opko Health Inc

Exchange NASDAQ
Headquaters Miami, FL, United States
IPO Launch date 1995-11-02
Chairman & CEO Dr. Phillip Frost Ph.D.
Sector Healthcare
Industry Diagnostics & Research
Full time employees 2997
Full time employees 2997

OPKO Health, Inc., a healthcare company, engages in the diagnostics and pharmaceuticals businesses in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company's Diagnostics segment operates BioReference Laboratories that offers laboratory testing services for the detection, diagnosis, evaluation, monitoring, and treatment of diseases, including esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare to physician offices, clinics, hospitals, employers, and governmental units; and 4Kscore prostate cancer test. Its Pharmaceutical segment offers Rayaldee to treat secondary hyperparathyroidism in adults with stage 3 or 4 chronic kidney disease, and vitamin D insufficiency. This segment also develops multi-specific immune therapies focused on oncology, immunology, and infectious diseases; OPK88004, an orally administered selective androgen receptor modulator; OPK88003, a once-weekly administered peptide for the treatment of type 2 diabetes and related obesity; Somatrogon (hGH-CTP), a once-weekly human growth hormone injection; and Factor VIIa-CTP, a novel long-acting coagulation factor being developed to treat hemophilia. In addition, it develops and commercializes longer-acting proprietary versions of already approved therapeutic proteins or peptides; develops and produces specialty APIs; develops, manufactures, markets, and sells pharmaceutical, nutraceutical, veterinary, and ophthalmic products; commercializes food supplements and over the counter products; manufactures and sells products primarily in the generics market; and markets, distributes, and sells pharmaceutical products in a range of indications, including cardiovascular products, vaccines, antibiotics, gastro-intestinal products, hormones, and others. The company also operates pharmaceutical platforms in Spain, Ireland, Chile, and Mexico. The company was founded in 2007 and is headquartered in Miami, Florida.

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