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ONC
Upturn stock ratingUpturn stock rating

BeiGene, Ltd. (ONC)

Upturn stock ratingUpturn stock rating
$262.6
Delayed price
Profit since last BUY18.17%
upturn advisory
Consider higher Upturn Star rating
BUY since 46 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
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Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
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Time period over
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Upturn Advisory Summary

03/27/2025: ONC (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

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Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

AI Based Fundamental Rating

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Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Analysis of Past Performance

Type Stock
Historic Profit 4.51%
Avg. Invested days 33
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 03/27/2025

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 28.48B USD
Price to earnings Ratio -
1Y Target Price 331.74
Price to earnings Ratio -
1Y Target Price 331.74
Volume (30-day avg) 556269
Beta 0.65
52 Weeks Range 126.97 - 287.88
Updated Date 03/27/2025
52 Weeks Range 126.97 - 287.88
Updated Date 03/27/2025
Dividends yield (FY) -
Basic EPS (TTM) -6.12

Earnings Date

Report Date 2025-02-27
When -
Estimate -1.0175
Actual -1.43

Profitability

Profit Margin -16.92%
Operating Margin (TTM) -6.31%

Management Effectiveness

Return on Assets (TTM) -6.07%
Return on Equity (TTM) -18.77%

Valuation

Trailing PE -
Forward PE 204.08
Enterprise Value 26930518296
Price to Sales(TTM) 7.47
Enterprise Value 26930518296
Price to Sales(TTM) 7.47
Enterprise Value to Revenue 7.07
Enterprise Value to EBITDA -
Shares Outstanding 98684704
Shares Floating 958920813
Shares Outstanding 98684704
Shares Floating 958920813
Percent Insiders 19.24
Percent Institutions 42.52

Analyst Ratings

Rating 4.48
Target Price 280.92
Buy 7
Strong Buy 12
Buy 7
Strong Buy 12
Hold 2
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

BeiGene, Ltd.

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Company Overview

History and Background

BeiGene, Ltd. was founded in 2010 as a biotechnology company focused on developing and commercializing innovative oncology medications. It has grown from a research-focused startup to a global company with operations in multiple countries and a portfolio of approved and investigational drugs.

Core Business Areas

  • Research and Development: Focused on discovering and developing novel cancer therapies, utilizing its internal research capabilities and collaborations.
  • Commercialization: Marketing and selling its approved drugs in various markets, including the United States, China, and Europe.
  • Manufacturing: Manufacturing capabilities to produce its own drugs and manage the supply chain effectively.

Leadership and Structure

BeiGene is led by a team of experienced executives in the pharmaceutical and biotechnology industries. The organizational structure includes research, development, commercial, and manufacturing departments, reflecting its integrated business model.

Top Products and Market Share

Key Offerings

  • Brukinsa (zanubrutinib): A BTK inhibitor approved for various hematological malignancies. It competes with Imbruvica (ibrutinib) and Calquence (acalabrutinib). While precise market share data is dynamic, Brukinsa is gaining traction in the BTK inhibitor market. Revenue has steadily increased, surpassing $1 billion in 2023. Competitors include AbbVie and AstraZeneca.
  • Tislelizumab: A PD-1 inhibitor approved in China for various solid tumors. Competition includes other PD-1 inhibitors from companies like Merck (Keytruda) and Bristol Myers Squibb (Opdivo). Tislelizumab holds a significant market share in China, but its global presence is still developing. Market share data is region-specific and varies. Competitors include Merck and Bristol Myers Squibb.

Market Dynamics

Industry Overview

The oncology drug market is characterized by high growth, intense competition, and rapid innovation. There is a strong demand for novel therapies with improved efficacy and safety profiles. Increasing cancer incidence and aging populations drive market expansion.

Positioning

BeiGene is positioned as a global biotechnology company focused on developing innovative and affordable cancer medicines. Its competitive advantage lies in its strong research capabilities, global presence, and commitment to addressing unmet medical needs in oncology.

Total Addressable Market (TAM)

The global oncology drug market is projected to reach $300 billion+ by 2028. BeiGene is positioned to capture a significant portion of this TAM through its portfolio of approved and investigational drugs, as well as through strategic collaborations.

Upturn SWOT Analysis

Strengths

  • Innovative oncology pipeline
  • Global presence with operations in key markets
  • Strong research and development capabilities
  • Experienced management team
  • Growing commercial infrastructure

Weaknesses

  • Reliance on a few key products
  • Limited profitability
  • Dependence on partnerships for certain markets
  • Competition from established pharmaceutical companies

Opportunities

  • Expanding into new markets
  • Acquiring or licensing complementary technologies
  • Developing new indications for existing drugs
  • Forging strategic collaborations to accelerate drug development
  • Increasing demand for biosimilars in the China market

Threats

  • Regulatory challenges and delays
  • Competition from biosimilars and generics
  • Unfavorable pricing and reimbursement policies
  • Clinical trial failures
  • Economic downturns impacting healthcare spending

Competitors and Market Share

Key Competitors

  • ABBV
  • AZN
  • MRK
  • BMY

Competitive Landscape

BeiGene faces intense competition from established pharmaceutical companies with larger resources and broader portfolios. Its competitive advantage lies in its innovative pipeline and focus on developing affordable cancer medicines.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: BeiGene has experienced rapid growth in revenue and R&D investment over the past decade.

Future Projections: Analysts project continued revenue growth for BeiGene as its approved drugs gain market share and new products are launched. Profitability is expected to improve over time.

Recent Initiatives: Recent initiatives include expanding its commercial infrastructure in key markets, advancing its pipeline of investigational drugs, and forging strategic partnerships.

Summary

BeiGene is a promising biotechnology company with a growing portfolio of oncology drugs and a strong research pipeline. While the company has yet to achieve sustained profitability, its revenue growth and commitment to innovation are encouraging. BeiGene faces significant competition from established pharmaceutical companies but is well-positioned to capitalize on the growing demand for novel cancer therapies. Key areas to watch include regulatory approvals, clinical trial results, and market share gains for its key products.

Similar Companies

  • ABBV
  • AZN
  • MRK
  • BMY
  • GILD

Sources and Disclaimers

Data Sources:

  • Company filings, Analyst reports, Industry publications, Market research reports

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. Market data and projections are subject to change and may not be accurate.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About BeiGene, Ltd.

Exchange NASDAQ
Headquaters -
IPO Launch date 2016-02-03
Co-Founder, Executive Chairman & CEO Mr. John V. Oyler
Sector Healthcare
Industry Biotechnology
Full time employees 11000
Full time employees 11000

BeiGene, Ltd., an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company's commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton's Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; and PARTRUVIX, a selective small molecule inhibitor of PARP1 and PARP2 enzymes that is being evaluated as a monotherapy and in combinations for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK-targeting chimeric degradation activation compound active against wild-type and mutant BTK; Ociperlimab (BGB-A1217), a TIGIT inhibitor; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. BeiGene, Ltd. was incorporated in 2010 and is based in Camana Bay, the Cayman Islands.

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