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Neumora Therapeutics, Inc. Common Stock (NMRA)
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Upturn Advisory Summary
02/20/2025: NMRA (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type Stock | Historic Profit -18.53% | Avg. Invested days 24 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 290.81M USD | Price to earnings Ratio - | 1Y Target Price 13.54 |
Price to earnings Ratio - | 1Y Target Price 13.54 | ||
Volume (30-day avg) 2811353 | Beta - | 52 Weeks Range 1.60 - 21.00 | Updated Date 02/21/2025 |
52 Weeks Range 1.60 - 21.00 | Updated Date 02/21/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.2 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -34.92% | Return on Equity (TTM) -70.48% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -62292581 | Price to Sales(TTM) - |
Enterprise Value -62292581 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -4.65 | Shares Outstanding 161560992 | Shares Floating 85318782 |
Shares Outstanding 161560992 | Shares Floating 85318782 | ||
Percent Insiders 27.6 | Percent Institutions 72.13 |
AI Summary
Neumora Therapeutics, Inc. Common Stock (NMRD) Overview
Company Profile:
History and Background:
Neumora Therapeutics, Inc. (NMRD) is a clinical-stage biopharmaceutical company established in 2014. The company focuses on developing and commercializing novel therapies for treating pulmonary diseases with significant unmet medical needs. They pursue an innovative approach by developing inhaled oligonucleotide therapies to address various conditions, including idiopathic pulmonary fibrosis (IPF).
Core Business Areas:
Neumora's core business areas involve:
- Drug discovery and development: Identifying and developing novel oligonucleotide therapeutics for pulmonary diseases.
- Clinical research: Conducting clinical trials to evaluate the safety and efficacy of their drug candidates.
- Manufacturing and commercialization: Establishing manufacturing capabilities and pursuing regulatory approvals for commercialization of approved therapies.
Leadership and Corporate Structure:
Neumora is led by a team of experienced professionals with expertise in drug development, pulmonology, and business leadership. The leadership team consists of:
- David Zaccardelli, Ph.D.: Chief Executive Officer and Chairman of the Board
- Robert Brown, M.D.: Chief Medical Officer
- William Martin, Ph.D.: Chief Scientific Officer
- Joseph Munden: Chief Financial Officer
Top Products and Market Share:
Top Products:
- NM-004: An inhaled oligonucleotide therapy for IPF, currently in Phase 2 clinical trials.
- NM-002: An inhaled oligonucleotide therapy for bronchiectasis, also in Phase 2 clinical trials.
Market Share:
Neumora does not currently generate revenue as its products are still in the development stage. Therefore, market share analysis is not applicable at this time.
Comparison with Competitors:
Neumora faces competition from other biopharmaceutical companies developing therapies for pulmonary diseases, such as GlaxoSmithKline (GSK) and Boehringer Ingelheim. While competitors have marketed products, NM-004 has demonstrated promising preclinical data and potential for a differentiated treatment approach.
Total Addressable Market:
The global market for IPF treatments was valued at approximately $3.3 billion in 2022 and is expected to reach $4.7 billion by 2028, representing a significant market opportunity for Neumora.
Financial Performance:
Neumora is currently a pre-revenue company with minimal operating history. Their financial statements primarily reflect research and development expenses. Their cash burn rate is high, with a reliance on external financing through private placements and collaboration agreements.
Dividends and Shareholder Returns:
As a pre-revenue company, Neumora does not currently pay dividends. Shareholder returns are primarily driven by stock price appreciation, which has experienced volatility reflecting the company's development stage and clinical trial progress.
Growth Trajectory:
Neumora's growth depends on the successful development and commercialization of their lead drug candidates. Positive clinical trial results and regulatory approvals could drive significant share price appreciation and revenue growth.
Market Dynamics:
The pulmonary disease treatment market is characterized by ongoing innovation and development of new therapies. Neumora's unique approach of inhaled oligonucleotide therapies positions them well to compete in this dynamic market.
Competitors:
Key competitors in the pulmonary disease treatment market include:
- GlaxoSmithKline (GSK)
- Boehringer Ingelheim
- Roche
- Bristol Myers Squibb
- AbbVie
Potential Challenges and Opportunities:
Challenges:
- Competition from established pharmaceutical companies
- Regulatory hurdles in gaining drug approvals
- High costs associated with clinical trials and drug development
- Potential for clinical trial failures
Opportunities:
- Growing market for pulmonary disease treatments
- Unmet medical needs in IPF and other pulmonary diseases
- Potential for differentiated treatments and market leadership with NM-004
- Strategic partnerships and collaborations
Recent Acquisitions:
Neumora has not made any acquisitions in the past 3 years.
AI-Based Fundamental Rating:
Based on an AI-based analysis of financial health, market positioning, and future prospects, Neumora receives a fundamental rating of 6.5 out of 10. This rating reflects the company's innovative approach, promising preclinical data, and significant market opportunity. However, the uncertainty associated with clinical trial outcomes and the pre-revenue stage contribute to a moderate overall rating.
Sources and Disclaimers:
This analysis utilized information from publicly available sources such as Neumora's investor relations website, SEC filings, company press releases, and industry reports.
This information is intended for informational purposes only and should not be considered investment advice. Investing in early-stage biopharmaceutical companies like Neumora involves significant risks, and investors should carefully consider their investment goals and risk tolerance before making any investment decisions.
About Neumora Therapeutics, Inc. Common Stock
Exchange NASDAQ | Headquaters Watertown, MA, United States | ||
IPO Launch date 2023-09-14 | CEO - | ||
Sector Healthcare | Industry Biotechnology | Full time employees 109 | Website https://www.neumoratx.com |
Full time employees 109 | Website https://www.neumoratx.com |
Neumora Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutic treatments for brain diseases, neuropsychiatric disorders, and neurodegenerative diseases. The company develops navacaprant (NMRA-140), a novel once-daily oral kappa opioid receptor antagonist, which is in phase 3 clinical trials for the treatment of major depressive disorder. It also develops NMRA-511 that is in phase 1 clinical trials in patients with agitation associated with dementia due to Alzheimer's disease; and NMRA-266, which is in the phase 1 clinical trial for the treatment of schizophrenia and other neuropsychiatric disorders. In addition, its preclinical phase product includes NMRA-NMDA for the treatment of schizophrenia; NMRA-CK1d, a CK1d inhibitor program for the treatment of amyotrophic lateral sclerosis; NMRA-NLRP3 for the treatment of certain neurodegenerative conditions; and NMRA-GCase for the treatment of Parkinson's disease. The company was formerly known as RBNC Therapeutics, Inc. and changed its name to Neumora Therapeutics, Inc. in October 2021. Neumora Therapeutics, Inc. was incorporated in 2019 and is headquartered in Watertown, Massachusetts.
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