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Nektar Therapeutics (NKTR)NKTR
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Upturn Advisory Summary
11/20/2024: NKTR (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: -63.59% | Upturn Advisory Performance 1 | Avg. Invested days: 22 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 11/20/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: -63.59% | Avg. Invested days: 22 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 11/20/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 184.46M USD |
Price to earnings Ratio - | 1Y Target Price 4.1 |
Dividends yield (FY) - | Basic EPS (TTM) -0.84 |
Volume (30-day avg) 1705704 | Beta 0.61 |
52 Weeks Range 0.42 - 1.93 | Updated Date 11/20/2024 |
Company Size Small-Cap Stock | Market Capitalization 184.46M USD | Price to earnings Ratio - | 1Y Target Price 4.1 |
Dividends yield (FY) - | Basic EPS (TTM) -0.84 | Volume (30-day avg) 1705704 | Beta 0.61 |
52 Weeks Range 0.42 - 1.93 | Updated Date 11/20/2024 |
Earnings Date
Report Date 2024-11-07 | When AfterMarket |
Estimate -0.21 | Actual -0.18 |
Report Date 2024-11-07 | When AfterMarket | Estimate -0.21 | Actual -0.18 |
Profitability
Profit Margin -180.7% | Operating Margin (TTM) -142.18% |
Management Effectiveness
Return on Assets (TTM) -22.64% | Return on Equity (TTM) -161.63% |
Revenue by Products
Revenue by Products - Current and Previous Year
Revenue by Geography
Revenue by Geography - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 53759032 | Price to Sales(TTM) 1.98 |
Enterprise Value to Revenue 0.58 | Enterprise Value to EBITDA -6.5 |
Shares Outstanding 184458000 | Shares Floating 155039032 |
Percent Insiders 1.05 | Percent Institutions 76.69 |
Trailing PE - | Forward PE - | Enterprise Value 53759032 | Price to Sales(TTM) 1.98 |
Enterprise Value to Revenue 0.58 | Enterprise Value to EBITDA -6.5 | Shares Outstanding 184458000 | Shares Floating 155039032 |
Percent Insiders 1.05 | Percent Institutions 76.69 |
Analyst Ratings
Rating 3.33 | Target Price 2.88 | Buy 1 |
Strong Buy 1 | Hold 3 | Sell 1 |
Strong Sell - |
Rating 3.33 | Target Price 2.88 | Buy 1 | Strong Buy 1 |
Hold 3 | Sell 1 | Strong Sell - |
AI Summarization
Nektar Therapeutics (NKTR): A Comprehensive Overview
Company Profile
History and Background:
Founded in 1990, Nektar Therapeutics is a biopharmaceutical company developing and commercializing innovative therapies for cancer and other human diseases. Originally focused on polymers and drug delivery technologies, the company pivoted in 2012 to focus on therapeutic drugs. Their lead program involved NKTR-214, a potential treatment for advanced melanoma and other cancers.
Core Business Areas:
- Immuno-oncology: Nektar focuses on therapies that leverage the immune system to fight cancer, including NKTR-214 for the treatment of solid tumors and cetuximab-IL15 fusion protein for cancer immunotherapy.
- Medicinal and Diagnostic Solutions: This segment includes drug delivery technologies like PEGylation, which improves the effectiveness and safety of existing therapies.
Leadership & Corporate Structure:
- CEO: John L. McKearn
- President: David A. Park
- Board of Directors includes experienced executives and industry experts.
- Headquarters: Huntsville, Alabama.
Top Products and Market Share:
- Bempeg: Approved in 2022 in the US and Europe as an adjuvant therapy for reducing the risk of breast cancer recurrence.
- NKTR-181: In clinical development for various types of cancer using Nektar's proprietary ADC technology.
- NKTR-255: An inhaled IL-2 therapy for cancer immunotherapy undergoing Phase 1 clinical trials.
Market Share:
- Bempeg: Estimated to hold a small share of the breast cancer treatment market in the US and Europe.
- NKTR-181 and NKTR-255: Still in development, so no market share currently.
Comparison with Competitors:
- Competitors in the immuno-oncology space include Amgen, Bristol Myers Squibb, and Merck.
- Nektar's focus on NKTR-214 for solid tumors distinguishes them from many competitors who focus primarily on hematologic malignancies.
- In the ADC space, competitors include Seattle Genetics and Immunomedics.
- NKTR-181 has the potential to offer advantages over existing ADCs due to its improved efficacy and reduced toxicity.
Total Addressable Market
The global oncology drug market is expected to reach USD 208.1 billion by 2025. The addressable market for Nektar's therapies could be significant within this space, focusing on solid tumors and specific cancer types.
Financial Performance
Recent Financial Statements:
- Revenue: 2022 Q3 revenue was $112.6 million compared to $94.8 million in 2021 Q3.
- Net Income: Net loss of $34.5 million in 2022 Q3 compared to a net loss of $30.5 million in 2021 Q3.
- Profit Margin: Gross profit margin for 2022 Q3 was 72.2%.
- EPS: Diluted EPS was $(0.26) in 2022 Q3 compared to $(0.33) in 2021 Q3.
Growth Analysis:
Nektar has experienced moderate revenue growth in recent quarters, primarily driven by sales of Bempeg. However, they are still in the early stages of commercialization for Bempeg, and their other pipeline assets are not yet generating significant revenue.
Dividends and Shareholder Returns
- Nektar does not currently pay dividends.
- Shareholder returns over the past year have been negative due to stock price decline.
Market Dynamics
The oncology market is highly competitive and constantly evolving. Key trends include a focus on targeted therapies, immunotherapy, and combination therapies.
Competitive Advantages and Disadvantages:
Nektar's advantages include its innovative drug delivery technologies, its lead program NKTR-214, and partnership with major pharmaceutical companies. Their disadvantages include competition in the crowded oncology market, limited commercial experience, and lack of currently approved late-stage pipeline assets besides Bempeg.
Potential Challenges and Opportunities
Challenges:
- Competition in the oncology space is fierce with established players and new entrants.
- Clinical development of their pipeline assets could be delayed or unsuccessful.
- Obtaining and maintaining regulatory approvals for their therapies is crucial and challenging.
Opportunities:
- Expansion of Bempeg market share and potential approval in additional territories.
- Successful development and commercialization of NKTR-181 and other promising pipeline candidates.
- Partnering with other companies to access new markets, technologies, and resources.
Recent Acquisitions (past 3 years)::
Nektar has not made any acquisitions in the past 3 years.
AI-Based Fundamental Rating
Based on an AI-powered analysis of Nektar's fundamentals, the company receives a rating of 6 out of 10. This rating is based on factors such as the company's financials, market position, and future prospects. The company's strengths include its growing revenue and strong partnerships. However, the company's lack of profitability and late-stage pipeline assets pose significant challenges.
Sources
- Nektar Therapeutics website: https://www.nektar.com/
- Yahoo Finance: https://finance.yahoo.com/quote/NKTR/
- Medscape: https://reference.medscape.com/drug/bempedoic-acid-1031563
- MarketWatch: https://www.marketwatch.com/investing/stock/nktr
- Bloomberg: https://www.bloomberg.com/profile/company/1461239D:US
Disclaimer
This overview is for informational purposes only and should not be considered as investment advice. Please conduct further research before making any investment decisions.
Conclusion
Nektar Therapeutics is an intriguing company with several promising drug candidates in development. Their focus on novel drug delivery technologies and immuno-oncology positions them for potential growth in the competitive oncology market. However, investors should consider the company's lack of current profitability and late-stage assets before making an investment decision.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Nektar Therapeutics
Exchange | NASDAQ | Headquaters | San Francisco, CA, United States |
IPO Launch date | 1994-05-03 | CEO, President & Director | Mr. Howard W. Robin |
Sector | Healthcare | Website | https://www.nektar.com |
Industry | Biotechnology | Full time employees | 137 |
Headquaters | San Francisco, CA, United States | ||
CEO, President & Director | Mr. Howard W. Robin | ||
Website | https://www.nektar.com | ||
Website | https://www.nektar.com | ||
Full time employees | 137 |
Nektar Therapeutics, a biopharmaceutical company, focuses on discovering and developing therapies that selectively modulate the immune system to treat autoimmune disorders. It develops NKTR-358, a regulatory T (Treg) cell stimulator designed to address the imbalance in the immune system underlying autoimmune disorders and chronic inflammatory conditions; PEG-CSF1, a polyethylene glycol (PEG) modified hematopoietic colony stimulating factor protein that is engineered to selectively modulate resolution processes of inflammation and has applications in a number of therapeutic indications, including acute and chronic inflammation; Tumor necrosis factor (TNF) receptor type II (TNFR2) agonist asset is a bivalent antibody molecule used to selectively stimulate TNFR2 receptor activity, without modulation of the TNFR1 signaling; and NKTR-255, an IL-15 receptor agonist designed to boost the immune system's natural ability to fight cancer. The company serves its clients in the United States and internationally. It has collaboration agreements with Takeda Pharmaceutical Company Ltd.; AstraZeneca AB; UCB Pharma S.A.; F. Hoffmann-La Roche Ltd; Bausch Health Companies Inc.; Pfizer Inc.; Amgen Inc.; UCB Pharma (Biogen); Bristol-Myers Squibb Company; Merck KGaA; and SFJ Pharmaceuticals, Inc. The company was incorporated in 1990 and is headquartered in San Francisco, California.
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