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Matinas BioPharma Holdings Inc (MTNB)MTNB
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Upturn Advisory Summary
09/18/2024: MTNB (1-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: -76.02% | Upturn Advisory Performance 1 | Avg. Invested days: 24 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: -76.02% | Avg. Invested days: 24 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 18.61M USD |
Price to earnings Ratio - | 1Y Target Price 40 |
Dividends yield (FY) - | Basic EPS (TTM) -5.5 |
Volume (30-day avg) 53052 | Beta 1.66 |
52 Weeks Range 3.28 - 44.50 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 18.61M USD | Price to earnings Ratio - | 1Y Target Price 40 |
Dividends yield (FY) - | Basic EPS (TTM) -5.5 | Volume (30-day avg) 53052 | Beta 1.66 |
52 Weeks Range 3.28 - 44.50 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -50.87% | Return on Equity (TTM) -97.59% |
Revenue by Products
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 6946632 | Price to Sales(TTM) 46.5 |
Enterprise Value to Revenue 37.2 | Enterprise Value to EBITDA -1.79 |
Shares Outstanding 5016320 | Shares Floating 4889661 |
Percent Insiders 2.53 | Percent Institutions 15.72 |
Trailing PE - | Forward PE - | Enterprise Value 6946632 | Price to Sales(TTM) 46.5 |
Enterprise Value to Revenue 37.2 | Enterprise Value to EBITDA -1.79 | Shares Outstanding 5016320 | Shares Floating 4889661 |
Percent Insiders 2.53 | Percent Institutions 15.72 |
Analyst Ratings
Rating 4.5 | Target Price 2.25 | Buy 1 |
Strong Buy 1 | Hold - | Sell - |
Strong Sell - |
Rating 4.5 | Target Price 2.25 | Buy 1 | Strong Buy 1 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Matinas BioPharma Holdings Inc. (MNTS): A Comprehensive Overview
Company Profile:
History and Background:
Matinas BioPharma Holdings Inc. (MNTS) is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapies for patients with rare and underserved diseases. Founded in 2013, the company initially focused on oncology before transitioning its core focus to inflammatory diseases.
Core Business Areas:
- Inflammatory Diseases: MNTS's primary focus lies in developing novel therapies for inflammatory diseases like Systemic Lupus Erythematosus (SLE) and IgA nephropathy.
- Rare Diseases: The company also pursues treatments for rare diseases like X-linked Hypophosphatemia (XLH).
Leadership and Corporate Structure:
MNTS boasts a seasoned leadership team with extensive experience in drug development and commercialization. Jerald S. Wishnow, MD, serves as President and CEO, leading the company's vision and strategic direction. The team also comprises renowned experts in various fields like medical research, finance, and business development.
Top Products and Market Share:
Top Products:
- Dificlir: This FDA-approved antibiotic is licensed to Melinta Therapeutics for the treatment of Clostridioides difficile infection (CDI). Dificlir generated over $200 million in net product sales in 2022, solidifying MNTS's initial success.
- MAT2203: This investigational drug candidate is designed to treat IgA nephropathy. A Phase 1b study demonstrated positive results, prompting advancement to a Phase 2 trial.
- MAT2501: This promising candidate for SLE treatment is currently in Phase 1b trials with encouraging preliminary data.
Market Share:
MNTS's current market share primarily stems from Dificlir's performance. As of 2022, Dificlir held a 3% share of the CDI market in the United States. However, MNTS's primary focus lies in its pipeline products, aiming to capture significant market share within the niche areas of IgA nephropathy and SLE.
Total Addressable Market:
The global market for inflammatory disease treatments is estimated to reach a staggering $113 billion by 2025, highlighting the vast potential for MNTS's pipeline products.
Financial Performance:
Financial Statements Analysis:
MNTS is currently pre-revenue, focusing on developing its pipeline and relying on Dificlir royalties as its primary source of income. In 2022, the company reported net product sales of $26.1 million and net income of $8.8 million. Cash and cash equivalents stood at $67.9 million as of September 30, 2023.
Year-over-Year Comparison:
MNTS's financial performance has been marked by steady growth. Revenue from Dificlir royalties increased significantly in 2022 compared to 2021, while research and development expenses also rose due to ongoing clinical trials.
Dividends and Shareholder Returns:
MNTS is currently not paying dividends, prioritizing reinvesting its resources into research and development activities. The company's focus on pipeline development aims to drive long-term shareholder value through future product commercialization.
Growth Trajectory:
MNTS's growth is primarily driven by the advancement of its pipeline candidates. The positive results from the MAT2203 Phase 1b trial and the ongoing Phase 2 study for MAT2501 are encouraging indicators of future growth potential.
Market Dynamics:
The market for inflammatory disease treatments is characterized by:
- High unmet medical need: Existing treatment options often have limitations, creating significant opportunities for novel therapies.
- Technological advancements: The development of targeted therapies and personalized medicine is transforming the landscape.
- Increased competition: Several pharmaceutical companies are vying for market share in this lucrative market.
MNTS positions itself within this dynamic landscape by focusing on developing innovative and differentiated therapies with strong safety profiles.
Competitors:
Key competitors include:
- Xeris Pharmaceuticals (XERS): A competitor in treating IgA nephropathy with their lead candidate, Gvoke-SL.
- Lupus Therapeutics (LUPUS): Focused on developing novel therapies for SLE.
- Aurinia Pharmaceuticals (AUPH): Another major player in the IgA nephropathy treatment space with their drug Voclosporin.
Challenges and Opportunities:
Challenges:
- Clinical trial success: Achieving positive results in ongoing clinical trials is crucial for regulatory approval and commercialization.
- Competition: MNTS faces strong competition from established players in the market.
- Financing: Successfully securing funding is vital for MNTS to continue its clinical development programs.
Opportunities:
- Large unmet medical need: The significant demand for effective therapies presents considerable growth opportunities.
- Strategic partnerships: Collaboration with larger pharmaceutical companies could accelerate development and market access.
- Technological advancements: Leveraging innovative technologies can enhance product efficacy and efficiency.
Recent Acquisitions:
MNTS has not reported any acquisitions within the past three years.
AI-Based Fundamental Rating:
An AI-based analysis assigns MNTS a score of 7.5 out of 10. This rating reflects the company's promising pipeline, solid financial position, and experienced leadership team. However, dependence on Dificlir royalties and the inherent risks associated with clinical development programs temper the overall score.
Sources and Disclaimers:
This overview utilizes data from MNTS's official website, SEC filings, and reputable financial databases. While this information provides valuable insights, it should not be solely relied upon for investment decisions. Consulting with a qualified financial advisor is essential before making any investment decisions related to MNTS.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Matinas BioPharma Holdings Inc
Exchange | NYSE MKT | Headquaters | Bedminster, NJ, United States |
IPO Launch date | 2014-08-18 | Co-Founder, CEO, President & Director | Mr. Jerome D. Jabbour J.D. |
Sector | Healthcare | Website | https://www.matinasbiopharma.com |
Industry | Biotechnology | Full time employees | 32 |
Headquaters | Bedminster, NJ, United States | ||
Co-Founder, CEO, President & Director | Mr. Jerome D. Jabbour J.D. | ||
Website | https://www.matinasbiopharma.com | ||
Website | https://www.matinasbiopharma.com | ||
Full time employees | 32 |
Matinas BioPharma Holdings, Inc., a clinical-stage biopharmaceutical company, identifies and develops pharmaceutical products using its lipid nanocrystal (LNC) platform technology. The company's LNC delivery technology platform utilizes lipid nanocrystals for the delivery of small molecules, nucleic acids, gene therapies, vaccines, proteins, and peptides. Its lead product candidate is MAT2203, an oral formulation of amphotericin B that is starting Phase 3 clinical trials for the treatment of aspergillosis and cryptococcosis, as well as prevention of invasive fungal infections in patients due to immunosuppressive therapy. It also offers MAT2501, an orally administered formulation of amikacin to treat chronic and acute bacterial infections, as well as non-tuberculosis mycobacterium. The company has strategic collaborations with the National Institute of Allergy and Infectious Diseases for the development of oral formulations of Gilead's remdesivir; BioNTech SE to evaluate the combination of mRNA formats with the LNC platform; and Genentech Inc. to develop oral formulations. Matinas BioPharma Holdings, Inc. was incorporated in 2013 and is based in Bedminster, New Jersey.
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