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Merus BV (MRUS)MRUS
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Upturn Advisory Summary
09/18/2024: MRUS (4-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Profit: 61.47% | Upturn Advisory Performance 4 | Avg. Invested days: 35 |
Profits based on simulation | Stock Returns Performance 3 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: PASS |
Profit: 61.47% | Avg. Invested days: 35 |
Upturn Star Rating | Stock Returns Performance 3 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 4 |
Key Highlights
Company Size Mid-Cap Stock | Market Capitalization 3.42B USD |
Price to earnings Ratio - | 1Y Target Price 87.62 |
Dividends yield (FY) - | Basic EPS (TTM) -2.89 |
Volume (30-day avg) 409291 | Beta 1.12 |
52 Weeks Range 19.80 - 61.61 | Updated Date 09/18/2024 |
Company Size Mid-Cap Stock | Market Capitalization 3.42B USD | Price to earnings Ratio - | 1Y Target Price 87.62 |
Dividends yield (FY) - | Basic EPS (TTM) -2.89 | Volume (30-day avg) 409291 | Beta 1.12 |
52 Weeks Range 19.80 - 61.61 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -877.99% |
Management Effectiveness
Return on Assets (TTM) -19.62% | Return on Equity (TTM) -33.39% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 2640941997 | Price to Sales(TTM) 97.1 |
Enterprise Value to Revenue 75.04 | Enterprise Value to EBITDA -4.91 |
Shares Outstanding 68210496 | Shares Floating 62644504 |
Percent Insiders 2.04 | Percent Institutions 101.82 |
Trailing PE - | Forward PE - | Enterprise Value 2640941997 | Price to Sales(TTM) 97.1 |
Enterprise Value to Revenue 75.04 | Enterprise Value to EBITDA -4.91 | Shares Outstanding 68210496 | Shares Floating 62644504 |
Percent Insiders 2.04 | Percent Institutions 101.82 |
Analyst Ratings
Rating 4.79 | Target Price 45.7 | Buy 3 |
Strong Buy 11 | Hold - | Sell - |
Strong Sell - |
Rating 4.79 | Target Price 45.7 | Buy 3 | Strong Buy 11 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Merus N.V. (NASDAQ: MRUS): A Comprehensive Overview
Company Profile:
- Detailed history and background: Merus N.V. is a clinical-stage immuno-oncology company founded in 2003 and headquartered in Utrecht, Netherlands. Its US headquarters is in Gaithersburg, Maryland. Merus focuses on the discovery and development of innovative bispecific protein therapeutics that activate the immune system to eradicate tumors.
- Core business areas: Merus's core business areas include:
- Development of Biclonics: Proprietary bispecific full-length IgG antibodies designed to engage the immune system and directly target tumors.
- Clinical development: Merus is currently conducting multiple Phase 1/2 clinical trials evaluating its Biclonics in various solid tumors and hematological malignancies.
- Leadership team and corporate structure:
- Andrew J. J. Loudon, Ph.D., President, and Chief Executive Officer: Joined Merus in 2014, previously held leadership positions at Janssen Biotech and Johnson & Johnson.
- John T. Bard, M.B.A., Chief Financial Officer: Joined Merus in 2020, previously held executive positions at Argenx and Johnson & Johnson.
- Beth C. Stevens, M.D., Chief Medical Officer: Joined Merus in 2018, previously held leadership positions at Novartis and Genentech.
Top Products and Market Share:
- Top products and offerings: Merus's top Biclonics in development include:
- MCLA-158: Targets ROR1 and CD3 for the treatment of solid tumors.
- MCLA-128: Targets MUC1 and CD3 for the treatment of solid tumors.
- MCLA-117: Targets EGFR and CD3 for the treatment of solid tumors.
- Market share analysis: While Merus's products are still in the clinical phase, the company faces competition from other immuno-oncology players like Macrogenics (MGNX), ImmunoGen (IMGN), and Argenx (ARGX).
- Product performance and market reception: Merus's early-stage clinical data has shown promising results with some of its Biclonics, but it's still too early to assess their performance against competitors in the market.
Total Addressable Market:
- Market size: The global immuno-oncology market is estimated to reach $95.85 billion by 2025, according to a report by Allied Market Research. This indicates a significant potential for Merus to capture a substantial market share.
Financial Performance:
- Recent financial performance: Merus is a clinical-stage company with no currently marketed products. As of June 30, 2023, the company reported a net loss of $132.8 million for the first half of 2023, compared to a net loss of $48.7 million for the same period in 2022.
- Cash flow and balance sheet health: Merus has a strong cash position with $414.3 million in cash and cash equivalents as of June 30, 2023. The company's balance sheet is healthy with low debt levels.
Dividends and Shareholder Returns:
- Dividend history: Merus does not currently pay dividends due to its focus on research and development.
- Shareholder returns: Merus's stock price has been volatile in recent years, reflecting the high-risk nature of early-stage biotechnology companies.
Growth Trajectory:
- Historical growth analysis: Merus has experienced significant growth in recent years, driven by its promising clinical pipeline and increasing investor interest.
- Future growth projections: Merus projects to continue its growth trajectory with the advancement of its clinical programs and potential commercialization of its Biclonics in the future.
- Recent strategic initiatives: Merus has actively pursued strategic partnerships and collaborations to accelerate its development and commercialization efforts.
Market Dynamics:
- Industry trends: The immuno-oncology market is rapidly evolving with new therapies and technologies emerging continuously. Merus is well-positioned within this growing market with its innovative Biclonics platform.
- Adaptability to market changes: Merus's flexible research and development approach allows for adaptation to changing market dynamics and emerging scientific advancements.
Competitors:
- Key competitors:
- Macrogenics (MGNX)
- ImmunoGen (IMGN)
- Argenx (ARGX)
- Xencor (XNCR)
- MacroGenics (MGNX)
- Amgen (AMGN)
- Roche (RHHBY)
- Pfizer (PFE)
- Competitive advantages: Merus's differentiated Biclonics platform offers potential advantages over competitors, including increased efficacy and safety profile.
- Competitive disadvantages: Merus's lack of marketed products and early-stage pipeline put it at a disadvantage compared to established competitors.
Potential Challenges and Opportunities:
- Key challenges: Merus faces challenges such as demonstrating the safety and efficacy of its Biclonics in clinical trials, securing regulatory approvals, and competing in the crowded immuno-oncology market.
- Potential opportunities: Merus has significant opportunities to capture market share in the growing immuno-oncology market, establish itself as a leader in the field, and generate substantial revenue with successful product commercialization.
Recent Acquisitions:
- Merus has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating:
- Rating: 7 out of 10
- Justification: Merus demonstrates strong potential with its innovative Biclonics platform, promising clinical data, and experienced leadership team. However, the company's early-stage development and lack of marketed products present significant risks.
Sources and Disclaimers:
- Information for this analysis was gathered from Merus N.V.'s official website, SEC filings, investor presentations, and other publicly available sources.
- This analysis is for informational purposes only and should not be considered as investment advice. It is crucial to conduct your own research and due diligence before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Merus BV
Exchange | NASDAQ | Headquaters | - |
IPO Launch date | 2016-05-19 | CEO, President & Executive Director | Dr. Sven Ante Lundberg M.D. |
Sector | Healthcare | Website | https://www.merus.nl |
Industry | Biotechnology | Full time employees | 172 |
Headquaters | - | ||
CEO, President & Executive Director | Dr. Sven Ante Lundberg M.D. | ||
Website | https://www.merus.nl | ||
Website | https://www.merus.nl | ||
Full time employees | 172 |
Merus N.V., a clinical-stage immuno-oncology company, engages in the development of antibody therapeutics in the Netherlands. Its bispecific antibody candidate pipeline includes Zenocutuzumab (MCLA-128), which is in a phase 2 clinical trials for the treatment of patients with metastatic breast cancer and castration-resistant prostate cancer, as well as in Phase 1/2 clinical trials for the treatment of solid tumors that harbor Neuregulin 1. The company is also developing MCLA-158, which is in a phase I clinical trial for the treatment of solid tumors; MCLA-145, which is in phase 1 clinical trials for the treatment of solid tumors; MCLA-129, which is in phase 1/2 clinical trials for the treatment of patients with advanced non-small cell lung cancer and other solid tumors; and ONO-4685 that is Phase 1 clinical trial to treat relapsed/refractory T cell lymphoma. In addition, it has collaboration agreement with Betta Pharmaceuticals Co. Ltd for the research and development of stage bispecific antibody candidates include MCLA-129; collaboration with Incyte Corporation for the development of MCLA-145; and collaboration with Gilead Sciences, Inc. to discover novel antibody-based trispecific T-cell engagers. The company was incorporated in 2003 and is headquartered in Utrecht, the Netherlands.
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