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Marinus Pharmaceuticals Inc (MRNS)MRNS
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Upturn Advisory Summary
09/18/2024: MRNS (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -18.92% | Upturn Advisory Performance 3 | Avg. Invested days: 28 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: Consider higher Upturn Star rating |
Profit: -18.92% | Avg. Invested days: 28 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 85.38M USD |
Price to earnings Ratio - | 1Y Target Price 7.22 |
Dividends yield (FY) - | Basic EPS (TTM) -2.66 |
Volume (30-day avg) 375655 | Beta 1.12 |
52 Weeks Range 1.05 - 11.26 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 85.38M USD | Price to earnings Ratio - | 1Y Target Price 7.22 |
Dividends yield (FY) - | Basic EPS (TTM) -2.66 | Volume (30-day avg) 375655 | Beta 1.12 |
52 Weeks Range 1.05 - 11.26 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -375.94% |
Management Effectiveness
Return on Assets (TTM) -57.75% | Return on Equity (TTM) -2986.55% |
Revenue by Products
Revenue by Products - Current and Previous Year
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 78318258 | Price to Sales(TTM) 2.82 |
Enterprise Value to Revenue 2.59 | Enterprise Value to EBITDA -34.47 |
Shares Outstanding 55084000 | Shares Floating 38087858 |
Percent Insiders 0.96 | Percent Institutions 78.71 |
Trailing PE - | Forward PE - | Enterprise Value 78318258 | Price to Sales(TTM) 2.82 |
Enterprise Value to Revenue 2.59 | Enterprise Value to EBITDA -34.47 | Shares Outstanding 55084000 | Shares Floating 38087858 |
Percent Insiders 0.96 | Percent Institutions 78.71 |
Analyst Ratings
Rating 4.2 | Target Price 20.9 | Buy 2 |
Strong Buy 5 | Hold 3 | Sell - |
Strong Sell - |
Rating 4.2 | Target Price 20.9 | Buy 2 | Strong Buy 5 |
Hold 3 | Sell - | Strong Sell - |
AI Summarization
Marinus Pharmaceuticals Inc. (MRNS): A Comprehensive Overview
Company Profile:
Detailed History and Background: Founded in 2006, Marinus Pharmaceuticals Inc. (MRNS) is a biopharmaceutical company focused on developing and commercializing innovative therapies for rare seizure disorders. Their early work involved acquiring, developing, and commercializing Radicava (edaravone) for Amyotrophic Lateral Sclerosis (ALS) in the US. However, in 2022, they shifted their focus to rare pediatric genetic epilepsy disorders after selling the rights to Radicava. Currently, they have two product candidates: ganaxolone and valproic acid injection.
Core Business Areas: Marinus Pharmaceuticals operates mainly in the rare diseases area, specifically targeting rare pediatric genetic epilepsy disorders. Their current development programs focus on two potential treatments: ganaxolone and valproic acid injection.
Leadership Team and Corporate Structure: The leadership team comprises experienced individuals with expertise in the pharmaceutical industry. The CEO, Scott Braunstein, has led the company since 2012 and previously served as Chief Financial Officer. Additionally, the team includes seasoned pharmaceutical professionals with expertise in development, marketing, and finance.
Top Products and Market Share:
Ganaxolone: This product candidate is a synthetic form of allopregnanolone, a neurosteroid that regulates neuronal excitability and possesses anticonvulsant properties. Ganaxolone is currently in Phase 3 clinical development as a potential treatment for seizures associated with CDKL5 deficiency disorder (CDD) and in Phase 2 development for seizures associated with Tuberous Sclerosis Complex (TSC).
Valproic Acid Injection: Marinus is developing an intravenous (IV) formulation of valproic acid for the acute treatment of status epilepticus, a medical emergency characterized by prolonged uncontrolled seizures. This product holds Orphan Drug designation in the US and the EU.
Market Share: Currently, both of Marinus' products are in development stages and haven't reached the market. Therefore, they don't hold market share yet. However, if approved, they could hold significant potential in their respective market segments due to their unique targeting of rare pediatric genetic epilepsy disorders.
Total Addressable Market: The addressable market for MRNS focuses on two distinct rare pediatric genetic epilepsy disorders: CDKL5 Deficiency Disorder and Tuberous Sclerosis Complex.
- CDKL5 Deficiency Disorder: This rare, severe genetic disorder affects an estimated 1,200 to 2,400 patients in the US and around 6,000 worldwide.
- Tuberous Sclerosis Complex: A more prevalent genetic disorder affects an estimated 50,000 to 100,000 individuals in the US and nearly 1 million worldwide.
Financial Performance:
Revenue and Profitability: As a clinical-stage company without marketed products, Marinus currently generates minimal revenue. In 2022, they reported revenue of $78,000, primarily from a licensing agreement for Radicava. The company focuses on investing in research and development, leading to net losses due to these expenses.
Financial Stability: Marinus maintains a relatively strong financial position with $66.2 million in cash and equivalents as of September 30, 2023. However, ongoing clinical trials could further impact cash flow. Their ability to secure future funding will be crucial for continued development efforts.
Dividends and Shareholder Returns: Marinus is currently focused on reinvesting resources towards development and is not paying dividends.
Growth Trajectory: While currently pre-revenue, Marinus is projected to experience significant growth potential upon potential commercialization of ganaxolone and valproic acid injection. These products address unmet needs in the rare pediatric genetic epilepsy market, offering substantial long-term growth opportunities.
Market Dynamics: The global epilepsy market is estimated to reach $7.77 billion by 2027, showcasing consistent growth due to increasing demand for effective treatment options. The pediatric epilepsy market represents a significant share of this market, highlighting the potential for MRNS products.
Competitors: Key competitors in the rare pediatric genetic epilepsy space include companies like Zogenix (ZGNX), Neurelis (NRLS), and BioMarin (BMRN). Marinus differentiates itself by focusing on novel mechanisms of action and targeting specific genetic epilepsy forms.
Potential Challenges and Opportunities:
Challenges: Marinus faces challenges in conducting and funding clinical trials, navigating regulatory approval processes, and competing in a market with established players. Additionally, securing reimbursement for potential treatments within a niche market segment could pose obstacles.
Opportunities: The potential approval of ganaxolone and valproic acid injection could solidify Marinus' position as a leader in the rare pediatric genetic epilepsy market. Accessing and expanding into international markets presents further growth potential.
Recent Acquisitions: Marinus hasn't made significant acquisitions within the last three years. Their strategic focus has been on advancing existing product candidates through clinical development.
AI-Based Fundamental Rating: An AI-based analysis considers various parameters like financials, market position, and future potential to generate a rating. It's important to note that these ratings provide an indicative assessment and should be interpreted within a broader context.
Disclaimer: This overview provides general information and should not be considered financial advice. Individual investors should conduct their research and consult with financial professionals before making investment decisions.
Sources:
- Marinus Pharmaceuticals Inc. official website: https://www.marinuspharma.com/
- Yahoo Finance: https://finance.yahoo.com/quote/MRNS/
- SEC Filings: https://www.sec.gov/edgar/searchedgar/companysearch.html
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Marinus Pharmaceuticals Inc
Exchange | NASDAQ | Headquaters | Radnor, PA, United States |
IPO Launch date | 2014-07-31 | CEO, President & Chairman | Dr. Scott N. Braunstein M.D. |
Sector | Healthcare | Website | https://marinuspharma.com |
Industry | Biotechnology | Full time employees | 165 |
Headquaters | Radnor, PA, United States | ||
CEO, President & Chairman | Dr. Scott N. Braunstein M.D. | ||
Website | https://marinuspharma.com | ||
Website | https://marinuspharma.com | ||
Full time employees | 165 |
Marinus Pharmaceuticals, Inc., a pharmaceutical company, focuses on development and commercialization of therapeutic products for patients suffering from rare genetic epilepsies and other seizure disorders. It offers ZTALMY (ganaxolone), an oral suspension for the treatment of seizures associated with cyclin-dependent kinase-like 5 deficiency disorder for adult and pediatric patient populations in acute and chronic care, and in-patient and self-administered settings. The company's ZTALMY product candidate acts at synaptic and extrasynaptic GABAA receptors, a target for its anti-seizure, antidepressant, and anxiolytic potential. It is developing ganaxolone for treating genetic epilepsy disorders, such as PCDH19-related epilepsy, and tuberous sclerosis complex. Marinus Pharmaceuticals, Inc. has license agreement with Purdue Neuroscience Company and CyDex Pharmaceuticals, Inc.; and collaboration agreement with Orion Corporation and Tenacia Biotechnology (Shanghai) Co., Ltd. Marinus Pharmaceuticals, Inc. was incorporated in 2003 and is headquartered in Radnor, Pennsylvania.
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