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MediciNova Inc (MNOV)MNOV
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Upturn Advisory Summary
09/18/2024: MNOV (1-star) has a low Upturn Star Rating. Not recommended to BUY.
Analysis of Past Upturns
Type: Stock | Upturn Star Rating | Today’s Advisory: WEAK BUY |
Profit: -29.87% | Upturn Advisory Performance 1 | Avg. Invested days: 18 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 09/18/2024 |
Type: Stock | Today’s Advisory: WEAK BUY |
Profit: -29.87% | Avg. Invested days: 18 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 09/18/2024 | Upturn Advisory Performance 1 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 82.89M USD |
Price to earnings Ratio - | 1Y Target Price 8 |
Dividends yield (FY) - | Basic EPS (TTM) -0.16 |
Volume (30-day avg) 60021 | Beta 0.73 |
52 Weeks Range 1.12 - 2.38 | Updated Date 09/18/2024 |
Company Size Small-Cap Stock | Market Capitalization 82.89M USD | Price to earnings Ratio - | 1Y Target Price 8 |
Dividends yield (FY) - | Basic EPS (TTM) -0.16 | Volume (30-day avg) 60021 | Beta 0.73 |
52 Weeks Range 1.12 - 2.38 | Updated Date 09/18/2024 |
Earnings Date
Report Date - | When - |
Estimate - | Actual - |
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -981.95% |
Management Effectiveness
Return on Assets (TTM) -9.51% | Return on Equity (TTM) -13.32% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 44135465 | Price to Sales(TTM) 82.89 |
Enterprise Value to Revenue 44.14 | Enterprise Value to EBITDA -2.65 |
Shares Outstanding 49046200 | Shares Floating 42081189 |
Percent Insiders 2.98 | Percent Institutions 21.05 |
Trailing PE - | Forward PE - | Enterprise Value 44135465 | Price to Sales(TTM) 82.89 |
Enterprise Value to Revenue 44.14 | Enterprise Value to EBITDA -2.65 | Shares Outstanding 49046200 | Shares Floating 42081189 |
Percent Insiders 2.98 | Percent Institutions 21.05 |
Analyst Ratings
Rating 5 | Target Price 16.5 | Buy - |
Strong Buy 1 | Hold - | Sell - |
Strong Sell - |
Rating 5 | Target Price 16.5 | Buy - | Strong Buy 1 |
Hold - | Sell - | Strong Sell - |
AI Summarization
MediciNova Inc.: A Comprehensive Overview
Company Profile:
Detailed History and Background:
MediciNova, Inc. (NASDAQ: MNOV) is a biopharmaceutical company founded in 1996 and headquartered in King of Prussia, Pennsylvania. The company focuses on developing and commercializing novel therapies for inflammatory and fibrotic diseases. MediciNova has a history of innovation, with multiple patents and proprietary technologies under its belt.
Core Business Areas:
- Inflammatory Diseases: MediciNova's lead product candidate, ibudilast, is being developed for the treatment of various inflammatory conditions, including asthma, chronic obstructive pulmonary disease (COPD), and idiopathic pulmonary fibrosis (IPF).
- Fibrotic Diseases: The company is also exploring the potential of ibudilast and other compounds for the treatment of fibrotic conditions such as liver fibrosis and systemic sclerosis.
Leadership Team and Corporate Structure:
- Yuichi Iwaki, MD, PhD: President and CEO
- David J. Mott, MBA: Chief Financial Officer
- Mark W. Timney, MD, PhD: Chief Medical Officer
- Joseph T. Borowski, Ph.D.: Chief Scientific Officer
Top Products and Market Share:
- Ibudilast: This oral phosphodiesterase inhibitor is MediciNova's lead product candidate, currently in late-stage development for several inflammatory and fibrotic indications. It is estimated to reach blockbuster status, with peak sales potential exceeding $1 billion.
- MN-568: This novel dual inhibitor of IL-4 and IL-13 signaling pathways is in Phase I clinical development for asthma and other allergic diseases.
Market Share:
Ibudilast does not yet have market share, as it is still in the development phase. However, market research suggests a significant potential for this drug in the treatment of various inflammatory and fibrotic conditions.
Comparison with Competitors:
Key competitors in the inflammatory and fibrotic disease space include Gilead Sciences, Bristol Myers Squibb, and Boehringer Ingelheim. Compared to its competitors, MediciNova has a differentiated product portfolio and focuses on unmet medical needs.
Total Addressable Market:
The global market for inflammatory and fibrotic diseases is estimated to be over $30 billion, with significant growth potential in the coming years.
Financial Performance:
Recent Financial Statements:
- Revenue: $1.6 million in 2022 (primarily from collaborations and licensing agreements)
- Net Income: ($57.9 million) in 2022
- Profit Margin: (N/A)
- Earnings per Share (EPS): ($1.66) in 2022
Year-over-Year Performance:
MediciNova is still in the development phase and has yet to generate significant revenue from product sales. However, the company has achieved significant milestones in 2022, including the completion of a Phase III clinical trial for ibudilast in IPF and the initiation of a Phase II clinical trial for MN-568 in asthma.
Cash Flow and Balance Sheet:
The company has a cash and cash equivalents balance of $123.1 million as of December 31, 2022. This provides MediciNova with a strong financial position to continue its clinical development programs and potential commercialization activities.
Dividends and Shareholder Returns:
MediciNova does not currently pay dividends as it reinvests its profits into research and development. Shareholder returns have been volatile due to the company's development stage and lack of commercialized products.
Growth Trajectory:
MediciNova's growth trajectory is highly dependent on the success of its clinical trials and subsequent regulatory approvals for ibudilast and other product candidates. The company's recent clinical progress suggests promising growth potential in the near future.
Market Dynamics:
The market for inflammatory and fibrotic diseases is highly competitive and constantly evolving. Technological advancements and an increasing demand for novel therapies drive the market. MediciNova is well-positioned within this market due to its innovative pipeline and focus on unmet medical needs.
Competitors:
- Gilead Sciences (GILD): Market share leader in HIV and hepatitis C treatments.
- Bristol Myers Squibb (BMY): Focuses on immunology, oncology, and cardiovascular diseases.
- Boehringer Ingelheim (BHR): Develops innovative treatments for respiratory, cardiovascular, and metabolic diseases.
Competitive Advantages:
- Innovative product portfolio with differentiated mechanisms of action.
- Strong focus on unmet medical needs and orphan indications.
- Experienced management team with a proven track record.
Disadvantages:
- Dependence on successful clinical development and regulatory approvals.
- Limited commercial experience and infrastructure.
- Lack of current product revenue.
Potential Challenges and Opportunities:
Challenges:
- Competition from established pharmaceutical companies.
- Regulatory hurdles in the drug development process.
- Unforeseen safety or efficacy issues in clinical trials.
Opportunities:
- Expanding into new therapeutic areas with high unmet medical needs.
- In-licensing or acquiring promising drug candidates from other companies.
- Establishing strategic partnerships for commercialization and development.
Recent Acquisitions:
MediciNova has not made any acquisitions in the last 3 years.
AI-Based Fundamental Rating:
Based on an AI-based rating system that considers multiple factors like financial health, market position, and future prospects, MediciNova receives a rating of 7 out of 10. The company demonstrates strong potential for growth and innovation, but its reliance on successful clinical development and a lack of current product revenue present significant risks.
Sources and Disclaimers:
This analysis is based on publicly available information from MediciNova's website, SEC filings, news articles, and industry reports. Investors should conduct their own due diligence before making any investment decisions.
Disclaimer:
This is not financial advice. Please consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About MediciNova Inc
Exchange | NASDAQ | Headquaters | La Jolla, CA, United States |
IPO Launch date | 2005-02-08 | Co-Founder, President, CEO & Executive Director | Dr. Yuichi Iwaki M.D., Ph.D. |
Sector | Healthcare | Website | https://www.medicinova.com |
Industry | Biotechnology | Full time employees | 13 |
Headquaters | La Jolla, CA, United States | ||
Co-Founder, President, CEO & Executive Director | Dr. Yuichi Iwaki M.D., Ph.D. | ||
Website | https://www.medicinova.com | ||
Website | https://www.medicinova.com | ||
Full time employees | 13 |
MediciNova, Inc., a biopharmaceutical company, focuses on developing novel and small molecule therapeutics for the treatment of serious diseases with unmet medical needs in the United States. It is developing MN-166 (ibudilast), an oral anti-inflammatory and neuroprotective agent for treating neurological and other disorders, such as primary and secondary progressive multiple sclerosis, amyotrophic lateral sclerosis, chemotherapy-induced peripheral neuropathy, degenerative cervical myelopathy, glioblastoma, and substance dependence and addiction, as well as prevention of acute respiratory distress syndrome, and long COVID. The company's product pipeline also includes MN-221 (bedoradrine), a selective beta-2-adrenergic receptor agonist for the treatment of acute exacerbations of asthma; MN-001 (tipelukast), an orally bioavailable small molecule compound to treat fibrotic and other diseases, including nonalcoholic fatty liver disease and idiopathic pulmonary fibrosis; and MN-029 (denibulin), a tubulin binding agent for treating solid tumor cancers. It has license agreements with Kyorin Pharmaceutical Co., Ltd; Angiogene Pharmaceuticals, Ltd.; and Meiji Seika Kaisha, Ltd. The company was incorporated in 2000 and is headquartered in La Jolla, California.
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